Sstr2

Functionⁱ

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.2 Publications

GO - Molecular functionⁱ

neuropeptide binding Source: GO_Central
PDZ domain binding Source: MGI
somatostatin receptor activity
Source: MGI
Inferred from direct assayⁱ
- 7929134
- 1346068

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
Source: MGI
Inferred from direct assayⁱ
- 9166719
cellular response to estradiol stimulus Source: GO_Central
cellular response to glucocorticoid stimulus Source: GO_Central
cerebellum development Source: Ensembl
forebrain development Source: Ensembl
G-protein coupled receptor signaling pathway
Source: MGI
Inferred from mutant phenotypeⁱ
- 7929134
negative regulation of cell proliferation Source: GO_Central
neuropeptide signaling pathway
Source: MGI
Inferred from direct assayⁱ
- 9166719
peristalsis Source: MGI
regulation of muscle contraction Source: MGI
response to starvation Source: Ensembl
spermatogenesis Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptor, Receptor, Transducer

Molecular function

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactomeⁱ	R-MMU-375276 Peptide ligand-binding receptors R-MMU-418594 G alpha (i) signalling events

Reactomeⁱ

R-MMU-375276 Peptide ligand-binding receptors
R-MMU-418594 G alpha (i) signalling events

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Somatostatin receptor type 2 Short name: SS-2-R Short name: SS2-R Short name: SS2R Alternative name(s): SRIF-1
Gene namesⁱ	Name:Sstr2 Synonyms:Smstr2, Sst2
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 11

Organism-specific databases

MGIⁱ	MGI:98328 Sstr2

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 43	ExtracellularSequence analysisAdd BLAST	43
Transmembraneⁱ	44 – 67	Helical; Name=1Sequence analysisAdd BLAST	24
Topological domainⁱ	68 – 78	CytoplasmicSequence analysisAdd BLAST	11
Transmembraneⁱ	79 – 103	Helical; Name=2Sequence analysisAdd BLAST	25
Topological domainⁱ	104 – 118	ExtracellularSequence analysisAdd BLAST	15
Transmembraneⁱ	119 – 138	Helical; Name=3Sequence analysisAdd BLAST	20
Topological domainⁱ	139 – 161	CytoplasmicSequence analysisAdd BLAST	23
Transmembraneⁱ	162 – 181	Helical; Name=4Sequence analysisAdd BLAST	20
Topological domainⁱ	182 – 207	ExtracellularSequence analysisAdd BLAST	26
Transmembraneⁱ	208 – 229	Helical; Name=5Sequence analysisAdd BLAST	22
Topological domainⁱ	230 – 253	CytoplasmicSequence analysisAdd BLAST	24
Transmembraneⁱ	254 – 278	Helical; Name=6Sequence analysisAdd BLAST	25
Topological domainⁱ	279 – 288	ExtracellularSequence analysis	10
Transmembraneⁱ	289 – 303	Helical; Name=7Sequence analysisAdd BLAST	15
Topological domainⁱ	304 – 369	CytoplasmicSequence analysisAdd BLAST	66

Keywords - Cellular componentⁱ

Cell membrane, Cytoplasm, Membrane

Pathology & Biotechⁱ

Chemistry databases

ChEMBLⁱ	CHEMBL3207
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	356

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000070121	1 – 369	Somatostatin receptor type 2Add BLAST		369

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	9	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	22	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	29	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	32	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	115 ↔ 193	PROSITE-ProRule annotation
Lipidationⁱ	328	S-palmitoyl cysteineSequence analysis	1
Modified residueⁱ	341	PhosphoserineBy similarity	1
Modified residueⁱ	343	PhosphoserineBy similarity	1
Modified residueⁱ	348	PhosphoserineBy similarity	1
Modified residueⁱ	353	PhosphothreonineBy similarity	1
Modified residueⁱ	354	PhosphothreonineBy similarity	1

Post-translational modificationⁱ

Phosphorylated on serine and threonine residues in response to agonist stimulation, leading to receptor desensitization and rapid internalization. Phosphorylated to a greater extent on serine than threonine residues. Threonine phosphorylation is required for arrestin binding and receptor endocytosis but is not necessary for desensitization (By similarity).By similarity

Keywords - PTMⁱ

Disulfide bond, Glycoprotein, Lipoprotein, Palmitate, Phosphoprotein

Proteomic databases

PaxDbⁱ	P30875
PRIDEⁱ	P30875

PTM databases

iPTMnetⁱ	P30875
PhosphoSitePlusⁱ	P30875
SwissPalmⁱ	P30875

Expressionⁱ

Tissue specificityⁱ

Cerebrum and kidney.

Gene expression databases

Bgeeⁱ	ENSMUSG00000047904
CleanExⁱ	MM_SSTR2
Genevisibleⁱ	P30875 MM

Interactionⁱ

Subunit structureⁱ

Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain) (By similarity).By similarity

GO - Molecular functionⁱ

PDZ domain binding Source: MGI

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

IntActⁱ	P30875, 2 interactors
Molecular INTeraction database More...MINTⁱ	P30875
STRINGⁱ	10090.ENSMUSP00000068578

Chemistry databases

BindingDBⁱ

P30875

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P30875
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118797
HOGENOMⁱ	HOG000230485
HOVERGENⁱ	HBG106919
InParanoidⁱ	P30875
KEGG Orthology (KO) More...KOⁱ	K04218
OMAⁱ	CGIVWPE
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HEN
PhylomeDBⁱ	P30875
TreeFamⁱ	TF315737

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd15971 7tmA_SSTR2, 1 hit
InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000586 Somatstn_rcpt IPR002074 Somatstn_rcpt_2
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR00246 SOMATOSTATNR PR00588 SOMATOSTTN2R
SMARTⁱ	View protein in SMART SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequences (2)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform A (identifier: P30875-1) [UniParc]FASTA Add to basket

Also known as: SS2RA

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MEMSSEQLNG SQVWVSSPFD LNGSLGPSNG SNQTEPYYDM TSNAVLTFIY 
        60         70         80         90        100
FVVCVVGLCG NTLVIYVILR YAKMKTITNI YILNLAIADE LFMLGLPFLA 
       110        120        130        140        150
MQVALVHWPF GKAICRVVMT VDGINQFTSI FCLTVMSIDR YLAVVHPIKS 
       160        170        180        190        200
AKWRRPRTAK MINVAVWCVS LLVILPIMIY AGLRSNQWGR SSCTINWPGE 
       210        220        230        240        250
SGAWYTGFII YAFILGFLVP LTIICLCYLF IIIKVKSSGI RVGSSKRKKS 
       260        270        280        290        300
EKKVTRMVSI VVAVFIFCWL PFYIFNVSSV SVAISPTPAL KGMFDFVVIL 
       310        320        330        340        350
TYANSCANPI LYAFLSDNFK KSFQNVLCLV KVSGTEDGER SDSKQDKSRL 
       360 
NETTETQRTL LNGDLQTSI

Length:369

Mass (Da):41,222

Last modified:July 1, 1993 - v1

Checksum:ⁱA78845AF74823039

GO

Isoform B (identifier: P30875-2) [UniParc]FASTA Add to basket

Also known as: SS2RB

The sequence of this isoform differs from the canonical sequence as follows:
332-369: VSGTEDGERSDSKQDKSRLNETTETQRTLLNGDLQTSI → ADNSQSGAEDIIAWV

« Hide

        10         20         30         40         50
MEMSSEQLNG SQVWVSSPFD LNGSLGPSNG SNQTEPYYDM TSNAVLTFIY 
        60         70         80         90        100
FVVCVVGLCG NTLVIYVILR YAKMKTITNI YILNLAIADE LFMLGLPFLA 
       110        120        130        140        150
MQVALVHWPF GKAICRVVMT VDGINQFTSI FCLTVMSIDR YLAVVHPIKS 
       160        170        180        190        200
AKWRRPRTAK MINVAVWCVS LLVILPIMIY AGLRSNQWGR SSCTINWPGE 
       210        220        230        240        250
SGAWYTGFII YAFILGFLVP LTIICLCYLF IIIKVKSSGI RVGSSKRKKS 
       260        270        280        290        300
EKKVTRMVSI VVAVFIFCWL PFYIFNVSSV SVAISPTPAL KGMFDFVVIL 
       310        320        330        340 
TYANSCANPI LYAFLSDNFK KSFQNVLCLV KADNSQSGAE DIIAWV

Show »

Length:346

Mass (Da):38,587

Checksum:ⁱD7A20AEC1371C400

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	179	I → L in CAA48766 (PubMed:1397330).Curated		1
Sequence conflictⁱ	305	S → T in CAA48766 (PubMed:1397330).Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_001923	332 – 369	VSGTE…LQTSI → ADNSQSGAEDIIAWV in isoform B. CuratedAdd BLAST		38

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M81832 Genomic DNA Translation: AAA58256.1 X68951 mRNA Translation: CAA48766.1 AF008914 Genomic DNA Translation: AAD01419.1 AF008914 Genomic DNA Translation: AAD01420.1 S71756 mRNA Translation: AAP20804.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS25598.1 [P30875-2] CCDS59571.1 [P30875-1]
PIRⁱ	D41795 S29248
NCBI Reference Sequences More...RefSeqⁱ	NP_001036071.1, NM_001042606.2 [P30875-1] NP_033243.2, NM_009217.4 [P30875-2]

Genome annotation databases

Ensemblⁱ	ENSMUST00000067591; ENSMUSP00000068578; ENSMUSG00000047904 [P30875-2] ENSMUST00000106630; ENSMUSP00000102241; ENSMUSG00000047904 [P30875-2] ENSMUST00000146390; ENSMUSP00000138101; ENSMUSG00000047904 [P30875-1]
GeneIDⁱ	20606
KEGGⁱ	mmu:20606
UCSC genome browser More...UCSCⁱ	uc007mep.2 mouse [P30875-2] uc011yha.2 mouse [P30875-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
P30875	Somatostatin receptor type 2		HUMAN		369
SSTR2 isoform 1		PANTR		369
Somatostatin receptor 2		PANPA		369
Somatostatin receptor type 2-like protein		CAMFR		438
UPI00093E7482		great roundleaf bat		372
+106
P30875-2	Somatostatin sst2B receptor (Fragment)		RAT		144
UPI00034F7E08		HETGA		405
UPI000344601C		MUSPF		347
somatostatin receptor type 2 isoform X2		MESAU		346
UPI00042AD7B7		PERMB		346
+7

Protein	Similar proteins		Species	Score	Length
P30875	Somatostatin receptor type 2		HUMAN		369
SSTR2 isoform 1		PANTR		369
Somatostatin receptor 2		PANPA		369
Somatostatin receptor type 2-like protein		CAMFR		438
UPI00093E7482		great roundleaf bat		372
+210
P30875-2	Somatostatin sst2B receptor (Fragment)		RAT		144
UPI00034F7E08		HETGA		405
UPI000344601C		MUSPF		347
somatostatin receptor type 2 isoform X2		MESAU		346
UPI00042AD7B7		PERMB		346
+172

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M81832 Genomic DNA Translation: AAA58256.1 X68951 mRNA Translation: CAA48766.1 AF008914 Genomic DNA Translation: AAD01419.1 AF008914 Genomic DNA Translation: AAD01420.1 S71756 mRNA Translation: AAP20804.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS25598.1 [P30875-2] CCDS59571.1 [P30875-1]
PIRⁱ	D41795 S29248
NCBI Reference Sequences More...RefSeqⁱ	NP_001036071.1, NM_001042606.2 [P30875-1] NP_033243.2, NM_009217.4 [P30875-2]

3D structure databases

ProteinModelPortalⁱ	P30875
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	P30875, 2 interactors
Molecular INTeraction database More...MINTⁱ	P30875
STRINGⁱ	10090.ENSMUSP00000068578

Chemistry databases

BindingDBⁱ	P30875
ChEMBLⁱ	CHEMBL3207
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	356

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

PTM databases

iPTMnetⁱ	P30875
PhosphoSitePlusⁱ	P30875
SwissPalmⁱ	P30875

Proteomic databases

PaxDbⁱ	P30875
PRIDEⁱ	P30875

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	20606
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000067591; ENSMUSP00000068578; ENSMUSG00000047904 [P30875-2] ENSMUST00000106630; ENSMUSP00000102241; ENSMUSG00000047904 [P30875-2] ENSMUST00000146390; ENSMUSP00000138101; ENSMUSG00000047904 [P30875-1]
GeneIDⁱ	20606
KEGGⁱ	mmu:20606
UCSC genome browser More...UCSCⁱ	uc007mep.2 mouse [P30875-2] uc011yha.2 mouse [P30875-1]

Organism-specific databases

CTDⁱ	6752
MGIⁱ	MGI:98328 Sstr2

Phylogenomic databases

eggNOGⁱ	KOG3656 Eukaryota ENOG410XRW9 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118797
HOGENOMⁱ	HOG000230485
HOVERGENⁱ	HBG106919
InParanoidⁱ	P30875
KEGG Orthology (KO) More...KOⁱ	K04218
OMAⁱ	CGIVWPE
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HEN
PhylomeDBⁱ	P30875
TreeFamⁱ	TF315737

Enzyme and pathway databases

Reactomeⁱ	R-MMU-375276 Peptide ligand-binding receptors R-MMU-418594 G alpha (i) signalling events

Reactomeⁱ

R-MMU-375276 Peptide ligand-binding receptors
R-MMU-418594 G alpha (i) signalling events

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P30875
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000047904
CleanExⁱ	MM_SSTR2
Genevisibleⁱ	P30875 MM

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd15971 7tmA_SSTR2, 1 hit
InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000586 Somatstn_rcpt IPR002074 Somatstn_rcpt_2
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR00246 SOMATOSTATNR PR00588 SOMATOSTTN2R
SMARTⁱ	View protein in SMART SM01381 7TM_GPCR_Srsx, 1 hit
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SSR2_MOUSE
Accessionⁱ	P30875Primary (citable) accession number: P30875 Secondary accession number(s): P30934, Q91Y73
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 1, 1993
	Last sequence update:	July 1, 1993
	Last modified:	June 20, 2018
	This is version 162 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
SIMILARITY comments
Index of protein domains and families

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UniProtKB - P30875 (SSR2_MOUSE)

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Somatostatin receptor type 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Other locations

Cytosol

Plasma Membrane

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

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3D structure databases

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Chemistry databases

Protein family/group databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ