UniProtKB - P30799 (DDH_ZYMMO)
Protein
2-hydroxyacid dehydrogenase homolog
Gene
ddh
Organism
Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 236 | By similarity | 1 | |
Binding sitei | 260 | NADBy similarity | 1 | |
Active sitei | 265 | By similarity | 1 | |
Active sitei | 297 | Proton donorBy similarity | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 154 – 155 | NADBy similarity | 2 | |
Nucleotide bindingi | 234 – 236 | NADBy similarity | 3 | |
Nucleotide bindingi | 297 – 300 | NADBy similarity | 4 |
GO - Molecular functioni
- NAD binding Source: InterPro
- oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
Keywordsi
Molecular function | Oxidoreductase |
Ligand | NAD |
Enzyme and pathway databases
BioCyci | ZMOB264203:G1FZK-1123-MONOMER |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:ddh Synonyms:ldhA Ordered Locus Names:ZMO1237 |
Organismi | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) |
Taxonomic identifieri | 264203 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Sphingomonadales › Sphingomonadaceae › Zymomonas › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000076020 | 1 – 331 | 2-hydroxyacid dehydrogenase homologAdd BLAST | 331 |
Structurei
3D structure databases
ProteinModelPortali | P30799 |
SMRi | P30799 |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.Curated
Phylogenomic databases
HOGENOMi | HOG000136695 |
KOi | K03778 |
OMAi | THKAYNR |
OrthoDBi | 1638924at2 |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR029752 D-isomer_DH_CS1 IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00065 D_2_HYDROXYACID_DH_1, 1 hit PS00670 D_2_HYDROXYACID_DH_2, 1 hit PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
i Sequence
Sequence statusi: Complete.
P30799-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRVAIFSSKN YDHHSIEKEN EHYGHDLVFL NERLTKETAE KAKDAEAVCI
60 70 80 90 100
FVNDEANAEV LEILAGLGIK LVALRCAGYN NVDLDAAKKL NIKVVRVPAY
110 120 130 140 150
SPYSVAEYAV GMLLTLNRQI SRGLKRVREN NFSLEGLIGL DVHDKTVGII
160 170 180 190 200
GVGHIGSVFA HIMTHGFGAN VIAYKPHPDP ELAKKVGFRF TSLDEVIETS
210 220 230 240 250
DIISLHCPLT PENHHMINEE TLARAKKGFY LVNTSRGGLV DTKAVIKSLK
260 270 280 290 300
AKHLGGYAAD VYEEEGPLFF ENHADDIIED DILERLIAFP NVVFTGHQAF
310 320 330
LTKEALSNIA HSILQDISDA EAGKEMPDAL V
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 184 | K → E in AAA71934 (PubMed:8320209).Curated | 1 | |
Sequence conflicti | 219 | E → G in AAA71934 (PubMed:8320209).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L09650 Genomic DNA Translation: AAA71934.1 L09651 Unassigned DNA Translation: AAA71938.1 AE008692 Genomic DNA Translation: AAV89861.1 |
PIRi | D40649 |
RefSeqi | WP_011241053.1, NZ_CP023715.1 |
Genome annotation databases
EnsemblBacteriai | AAV89861; AAV89861; ZMO1237 |
GeneIDi | 33072570 |
KEGGi | zmo:ZMO1237 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L09650 Genomic DNA Translation: AAA71934.1 L09651 Unassigned DNA Translation: AAA71938.1 AE008692 Genomic DNA Translation: AAV89861.1 |
PIRi | D40649 |
RefSeqi | WP_011241053.1, NZ_CP023715.1 |
3D structure databases
ProteinModelPortali | P30799 |
SMRi | P30799 |
ModBasei | Search... |
MobiDBi | Search... |
Protocols and materials databases
Structural Biology Knowledgebase | Search... |
Genome annotation databases
EnsemblBacteriai | AAV89861; AAV89861; ZMO1237 |
GeneIDi | 33072570 |
KEGGi | zmo:ZMO1237 |
Phylogenomic databases
HOGENOMi | HOG000136695 |
KOi | K03778 |
OMAi | THKAYNR |
OrthoDBi | 1638924at2 |
Enzyme and pathway databases
BioCyci | ZMOB264203:G1FZK-1123-MONOMER |
Family and domain databases
InterProi | View protein in InterPro IPR006139 D-isomer_2_OHA_DH_cat_dom IPR029753 D-isomer_DH_CS IPR029752 D-isomer_DH_CS1 IPR006140 D-isomer_DH_NAD-bd IPR036291 NAD(P)-bd_dom_sf |
Pfami | View protein in Pfam PF00389 2-Hacid_dh, 1 hit PF02826 2-Hacid_dh_C, 1 hit |
SUPFAMi | SSF51735 SSF51735, 1 hit |
PROSITEi | View protein in PROSITE PS00065 D_2_HYDROXYACID_DH_1, 1 hit PS00670 D_2_HYDROXYACID_DH_2, 1 hit PS00671 D_2_HYDROXYACID_DH_3, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | DDH_ZYMMO | |
Accessioni | P30799Primary (citable) accession number: P30799 Secondary accession number(s): Q5NN49 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 1, 1993 |
Last sequence update: | February 15, 2005 | |
Last modified: | January 16, 2019 | |
This is version 108 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families