Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60 kDa chaperonin

Gene

groL

Organism
Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciAGRO:ATU0682-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
60 kDa chaperoninUniRule annotation
Alternative name(s):
GroEL proteinUniRule annotation
Protein Cpn60UniRule annotation
Gene namesi
Name:groLUniRule annotation
Synonyms:groELUniRule annotation, mopA
Ordered Locus Names:Atu0682
ORF Names:AGR_C_1220
OrganismiAgrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58))
Taxonomic identifieri176299 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupAgrobacteriumAgrobacterium tumefaciens complex
Proteomesi
  • UP000000813 Componenti: Chromosome circular

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000632561 – 54460 kDa chaperoninAdd BLAST544

Proteomic databases

PRIDEiP30779

Interactioni

Subunit structurei

Oligomer of 14 subunits composed of two stacked rings of 7 subunits.UniRule annotation

Protein-protein interaction databases

STRINGi176299.Atu0682

Structurei

3D structure databases

ProteinModelPortaliP30779
SMRiP30779
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chaperonin (HSP60) family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CJ9 Bacteria
COG0459 LUCA
HOGENOMiHOG000076290
KOiK04077
OMAiTDTDKME

Family and domain databases

CDDicd03344 GroEL, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
HAMAPiMF_00600 CH60, 1 hit
InterProiView protein in InterPro
IPR018370 Chaperonin_Cpn60_CS
IPR001844 Chaprnin_Cpn60
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00298 CHAPERONIN60
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 1 hit
TIGRFAMsiTIGR02348 GroEL, 1 hit
PROSITEiView protein in PROSITE
PS00296 CHAPERONINS_CPN60, 1 hit

Sequencei

Sequence statusi: Complete.

P30779-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAKEVKFGR SAREKMLKGV DILADAVKVT LGPKGRNVVI DKSFGAPRIT
60 70 80 90 100
KDGVSVAKEI ELEDKFENMG AQLVREVASK TNDIAGDGTT TATVLAQAIV
110 120 130 140 150
REGAKAVAAG MNPMDLKRGI DLAVAEVVKD LQAKAKKINT SEEVAQVGTI
160 170 180 190 200
SANGERQIGL DIAEAMQRVG NEGVITVEEA KTAETELEVV EGMQFDRGYL
210 220 230 240 250
SPYFVTNPEK MVADLEDAYI LLHEKKLSNL QAMLPVLEAV VQTGKPLVII
260 270 280 290 300
AEDVEGEALA TLVVNKLRGG LKIAAVKAPG FGDRRKAMLE DIAILTGGTV
310 320 330 340 350
ISEDLGIKLE SVTLDMLGKS KKVSISKENT TIVDGAGQKS DIEGRVAQIK
360 370 380 390 400
AQIEETTSDY DREKLQERLA KLAGGVAVIR VGGSTEVEVK EKKDRIDDAL
410 420 430 440 450
NATRAAVQEG IVPGGGVALL RSSTKITVKG VNDDQEAGIN IVRKALQSLV
460 470 480 490 500
RQIAENAGDE ASIVVGKILD KNEDNYGYNA QTGEYGDLIA LGIVDPVKVV
510 520 530 540
RTALQNAASV ASLLITTEAM IAELPKKESA MPQMPGGGMG GMDF
Length:544
Mass (Da):57,670
Last modified:March 27, 2002 - v2
Checksum:iB408D16FD9650046
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti8F → P (PubMed:8098329).Curated1
Sequence conflicti10R → A (PubMed:8098329).Curated1
Sequence conflicti48R → P in CAA48331 (PubMed:8098329).Curated1
Sequence conflicti258A → R in CAA48331 (PubMed:8098329).Curated1
Sequence conflicti513L → V in CAA48331 (PubMed:8098329).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X68263 Genomic DNA Translation: CAA48331.1
AE007869 Genomic DNA Translation: AAK86491.1
PIRiAD2660
B97442
S23918
RefSeqiNP_353706.1, NC_003062.2
WP_006313163.1, NC_003062.2

Genome annotation databases

EnsemblBacteriaiAAK86491; AAK86491; Atu0682
GeneIDi1132720
KEGGiatu:Atu0682
PATRICifig|176299.10.peg.678

Similar proteinsi

Entry informationi

Entry nameiCH60_AGRFC
AccessioniPrimary (citable) accession number: P30779
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1993
Last sequence update: March 27, 2002
Last modified: May 23, 2018
This is version 118 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health