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Entry version 130 (08 May 2019)
Sequence version 5 (01 Mar 2004)
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Protein

Putative transporter svop-1

Gene

svop-1

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processTransport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative transporter svop-1Curated
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:svop-1Imported
ORF Names:ZK637.1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegans
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

WormBase

More...
WormBasei
ZK637.1 ; CE32291 ; WBGene00014021 ; svop-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 85CytoplasmicSequence analysisAdd BLAST85
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei86 – 106Helical; Name=1Sequence analysisAdd BLAST21
Topological domaini107 – 120ExtracellularSequence analysisAdd BLAST14
Transmembranei121 – 141Helical; Name=2Sequence analysisAdd BLAST21
Topological domaini142 – 157CytoplasmicSequence analysisAdd BLAST16
Transmembranei158 – 178Helical; Name=3Sequence analysisAdd BLAST21
Topological domaini179ExtracellularSequence analysis1
Transmembranei180 – 200Helical; Name=4Sequence analysisAdd BLAST21
Topological domaini201 – 208CytoplasmicSequence analysis8
Transmembranei209 – 229Helical; Name=5Sequence analysisAdd BLAST21
Topological domaini230 – 237ExtracellularSequence analysis8
Transmembranei238 – 258Helical; Name=6Sequence analysisAdd BLAST21
Topological domaini259 – 319CytoplasmicSequence analysisAdd BLAST61
Transmembranei320 – 340Helical; Name=7Sequence analysisAdd BLAST21
Topological domaini341 – 372ExtracellularSequence analysisAdd BLAST32
Transmembranei373 – 393Helical; Name=8Sequence analysisAdd BLAST21
Topological domaini394 – 410CytoplasmicSequence analysisAdd BLAST17
Transmembranei411 – 431Helical; Name=9Sequence analysisAdd BLAST21
Topological domaini432 – 434ExtracellularSequence analysis3
Transmembranei435 – 455Helical; Name=10Sequence analysisAdd BLAST21
Topological domaini456 – 461CytoplasmicSequence analysis6
Transmembranei462 – 487Helical; Name=11Sequence analysisAdd BLAST26
Topological domaini488 – 489ExtracellularSequence analysis2
Transmembranei490 – 509Helical; Name=12Sequence analysisAdd BLAST20
Topological domaini510 – 520CytoplasmicSequence analysisAdd BLAST11

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000504661 – 520Putative transporter svop-1CuratedAdd BLAST520

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P30638

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P30638

PeptideAtlas

More...
PeptideAtlasi
P30638

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00014021 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.ZK637.1

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG0253 Eukaryota
ENOG410ZVDQ LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155403

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000114543

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P30638

Identification of Orthologs from Complete Genome Data

More...
OMAi
EYVLIMT

Database of Orthologous Groups

More...
OrthoDBi
1430447at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P30638

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06174 MFS, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR004749 Orgcat_transp/SVOP

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00083 Sugar_tr, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF103473 SSF103473, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00898 2A0119, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50850 MFS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P30638-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDKAILTEV LEASNLTEAY VDLTAKQLIK EIRHVGDDFA VRYSNLDDRT
60 70 80 90 100
ELGEPTDQRS PDSEKTFTVD EAVEALGFGR FQLKLSILTG MAWMADAMEM
110 120 130 140 150
MLLSLISPAL ACEWGISSVQ QALVTTCVFS GMMLSSTFWG KICDRFGRRK
160 170 180 190 200
GLTFSTLVAC IMGVISGMSP HFYVLLFFRG LTGFGIGGVP QSVTLYAEFL
210 220 230 240 250
PTAQRAKCVV LIESFWAIGA VFEALLAYFV MESFGWRALM FLSSLPLGIF
260 270 280 290 300
AVASFWLPES ARFDMASGHP ERALETLQAA ARMNRVQLPT GRLVSSTKAG
310 320 330 340 350
SESRGDIANL LSPDLRKTTI LLWCIWAITA FSYYGMVLFT TVLFQSHDEC
360 370 380 390 400
HGGLFSNGTQ MEVCQPLTRS DYFDLLSTTL AEFPGLIITV LIIEWFGRKK
410 420 430 440 450
TMALEYAVFA IFTFLLYFCL DRFTVTVLIF VARAFISGAF QCAYVYTPEV
460 470 480 490 500
YPTTLRAVGL GTCSAMARIG AIVTPFIAQV ASEKSLSLPI GIYGTAAILG
510 520
LIASLSLPIE TKGRQMMDSH
Length:520
Mass (Da):57,203
Last modified:March 1, 2004 - v5
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i203CC886A79343E1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
Z11115, Z22175 Genomic DNA Translation: CAA77460.2

Protein sequence database of the Protein Information Resource

More...
PIRi
S15786
T23190

NCBI Reference Sequences

More...
RefSeqi
NP_498960.2, NM_066559.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
ZK637.1.1; ZK637.1.1; WBGene00014021
ZK637.1.2; ZK637.1.2; WBGene00014021

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
176250

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_ZK637.1

UCSC genome browser

More...
UCSCi
ZK637.1.1 c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z11115, Z22175 Genomic DNA Translation: CAA77460.2
PIRiS15786
T23190
RefSeqiNP_498960.2, NM_066559.5

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi6239.ZK637.1

Proteomic databases

EPDiP30638
PaxDbiP30638
PeptideAtlasiP30638

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiZK637.1.1; ZK637.1.1; WBGene00014021
ZK637.1.2; ZK637.1.2; WBGene00014021
GeneIDi176250
KEGGicel:CELE_ZK637.1
UCSCiZK637.1.1 c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
176250
WormBaseiZK637.1 ; CE32291 ; WBGene00014021 ; svop-1

Phylogenomic databases

eggNOGiKOG0253 Eukaryota
ENOG410ZVDQ LUCA
GeneTreeiENSGT00940000155403
HOGENOMiHOG000114543
InParanoidiP30638
OMAiEYVLIMT
OrthoDBi1430447at2759
PhylomeDBiP30638

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P30638

Gene expression databases

BgeeiWBGene00014021 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR020846 MFS_dom
IPR005828 MFS_sugar_transport-like
IPR036259 MFS_trans_sf
IPR004749 Orgcat_transp/SVOP
PfamiView protein in Pfam
PF00083 Sugar_tr, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
TIGRFAMsiTIGR00898 2A0119, 1 hit
PROSITEiView protein in PROSITE
PS50850 MFS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSVOP_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P30638
Secondary accession number(s): Q21101
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: March 1, 2004
Last modified: May 8, 2019
This is version 130 of the entry and version 5 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
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