Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Metallothionein

Gene

smtA

Organism
Synechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in essential metal ion homeostasis (especially zinc homeostasis) and resistance to certain non-essential metal ions. Metallothioneins have a high content of cysteine residues that bind various heavy metals.

GO - Molecular functioni

Keywordsi

LigandCadmium, Copper, Mercury, Metal-binding, Metal-thiolate cluster, Zinc

Enzyme and pathway databases

BioCyciSYNEL:SYNPCC7942_1290-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Metallothionein
Short name:
MT
Gene namesi
Name:smtA
Ordered Locus Names:Synpcc7942_1290
OrganismiSynechococcus elongatus (strain PCC 7942) (Anacystis nidulans R2)
Taxonomic identifieri1140 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaSynechococcalesSynechococcaceaeSynechococcus
Proteomesi
  • UP000002717 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved
ChainiPRO_00001973712 – 56MetallothioneinAdd BLAST55

Proteomic databases

PRIDEiP30331

Expressioni

Inductioni

Upon exposure to a range of metals, particularly cadmium, zinc, copper and mercury.

Interactioni

Protein-protein interaction databases

STRINGi1140.Synpcc7942_1290

Structurei

Secondary structure

156
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP30331
SMRiP30331
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP30331

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4106DI1 Bacteria
ENOG410Y0GM LUCA
HOGENOMiHOG000032800
KOiK21904
OrthoDBiPOG091H0SC6

Family and domain databases

InterProiView protein in InterPro
IPR017854 Metalthion_dom_sf
IPR000518 Metalthion_fam14_prok
PfamiView protein in Pfam
PF02069 Metallothio_Pro, 1 hit
PRINTSiPR00859 MTPROKARYOTE
ProDomiView protein in ProDom or Entries sharing at least one domain
PD019076 Metallthion_Pro, 1 hit
SUPFAMiSSF57868 SSF57868, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P30331-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTSTTLVKCA CEPCLCNVDP SKAIDRNGLY YCSEACADGH TGGSKGCGHT

GCNCHG
Length:56
Mass (Da):5,741
Last modified:January 23, 2007 - v2
Checksum:iE76846D6086F2524
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X64585 Genomic DNA Translation: CAA45873.1
CP000100 Genomic DNA Translation: ABB57320.1
PIRiS31198
RefSeqiWP_011377964.1, NC_007604.1

Genome annotation databases

EnsemblBacteriaiABB57320; ABB57320; Synpcc7942_1290
KEGGisyf:Synpcc7942_1290

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X64585 Genomic DNA Translation: CAA45873.1
CP000100 Genomic DNA Translation: ABB57320.1
PIRiS31198
RefSeqiWP_011377964.1, NC_007604.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1JJDNMR-A2-56[»]
ProteinModelPortaliP30331
SMRiP30331
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi1140.Synpcc7942_1290

Proteomic databases

PRIDEiP30331

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABB57320; ABB57320; Synpcc7942_1290
KEGGisyf:Synpcc7942_1290

Phylogenomic databases

eggNOGiENOG4106DI1 Bacteria
ENOG410Y0GM LUCA
HOGENOMiHOG000032800
KOiK21904
OrthoDBiPOG091H0SC6

Enzyme and pathway databases

BioCyciSYNEL:SYNPCC7942_1290-MONOMER

Miscellaneous databases

EvolutionaryTraceiP30331

Family and domain databases

InterProiView protein in InterPro
IPR017854 Metalthion_dom_sf
IPR000518 Metalthion_fam14_prok
PfamiView protein in Pfam
PF02069 Metallothio_Pro, 1 hit
PRINTSiPR00859 MTPROKARYOTE
ProDomiView protein in ProDom or Entries sharing at least one domain
PD019076 Metallthion_Pro, 1 hit
SUPFAMiSSF57868 SSF57868, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiMT_SYNE7
AccessioniPrimary (citable) accession number: P30331
Secondary accession number(s): Q31NP9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 1, 1993
Last sequence update: January 23, 2007
Last modified: November 22, 2017
This is version 103 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Metallothioneins
    Classification of metallothioneins and list of entries
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again