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UniProtKB - P30314 (DPOL_BPSP1)
Protein
DNA polymerase
Gene
31
Organism
Bacillus phage SP01 (Bacteriophage SP01)
Status
Functioni
Replicates viral genomic DNA. This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'-5' direction.
By similarityCatalytic activityi
- EC:2.7.7.7
GO - Molecular functioni
- 3'-5' exonuclease activity Source: InterPro
- DNA binding Source: UniProtKB-KW
- DNA-directed DNA polymerase activity Source: UniProtKB-KW
GO - Biological processi
- DNA-dependent DNA replication Source: InterPro
- viral DNA genome replication Source: UniProtKB-KW
Keywordsi
Molecular function | DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase |
Biological process | DNA replication, Viral DNA replication |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:31 |
Organismi | Bacillus phage SP01 (Bacteriophage SP01) |
Taxonomic identifieri | 10685 [NCBI] |
Taxonomic lineagei | Viruses › Duplodnaviria › Heunggongvirae › Uroviricota › Caudoviricetes › Caudovirales › Herelleviridae › Spounavirinae › Okubovirus |
Virus hosti | Bacillus subtilis [TaxID: 1423] |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000101265 | 1 – 924 | DNA polymeraseAdd BLAST | 924 |
Proteomic databases
PRIDEi | P30314 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 235 – 386 | 3'-5' exonucleaseSequence analysisAdd BLAST | 152 |
Sequence similaritiesi
Belongs to the DNA polymerase type-A family.Curated
Family and domain databases
Gene3Di | 3.30.420.10, 1 hit 3.40.470.10, 1 hit |
InterProi | View protein in InterPro IPR002562, 3'-5'_exonuclease_dom IPR019760, DNA-dir_DNA_pol_A_CS IPR001098, DNA-dir_DNA_pol_A_palm_dom IPR043502, DNA/RNA_pol_sf IPR002298, DNA_polymerase_A IPR012337, RNaseH-like_sf IPR036397, RNaseH_sf IPR005122, Uracil-DNA_glycosylase-like IPR036895, Uracil-DNA_glycosylase-like_sf |
PANTHERi | PTHR10133, PTHR10133, 1 hit |
Pfami | View protein in Pfam PF00476, DNA_pol_A, 1 hit PF01612, DNA_pol_A_exo1, 1 hit PF03167, UDG, 1 hit |
PRINTSi | PR00868, DNAPOLI |
SMARTi | View protein in SMART SM00474, 35EXOc, 1 hit SM00482, POLAc, 1 hit |
SUPFAMi | SSF52141, SSF52141, 1 hit SSF53098, SSF53098, 1 hit SSF56672, SSF56672, 1 hit |
PROSITEi | View protein in PROSITE PS00447, DNA_POLYMERASE_A, 1 hit |
i Sequence
Sequence statusi: Complete.
P30314-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGSALDTLKE FNPKPMKGQG SKKARIIIVQ ENPFDYEYRK KKYMTGKAGK
60 70 80 90 100
LLKFGLAEVG IDPDEDVYYT SIVKYPTPEN RLPTPDEIKE SMDYMWAEIE
110 120 130 140 150
VIDPDIIIPT GNLSLKFLTK MTAITKVRGK LYEIEGRKFF PMIHPNTVLK
160 170 180 190 200
QPKYQDFFIK DLEILASLLE GKTPKNVLAF TKERRYCDTF EDAIDEIKRY
210 220 230 240 250
LELPAGSRVV IDLETVKTNP FIEKVTMKKT TLEAYPMSQQ PKIVGIGLSD
260 270 280 290 300
RSGYGCAIPL YHRENLMKGN QIGTIVKFLR KLLEREDLEF IAHNGKFDIR
310 320 330 340 350
WLRASLDIYL DISIWDTMLI HIIDYRGERY SWSKRLAWLE TDMGGYDDAL
360 370 380 390 400
DGEKPKGEDE GNYDLIPWDI LKVYLADDCD VTFRLSEKYI PLVEENEEKK
410 420 430 440 450
WLWENIMVPG YYTLLDIEMD GIHVDREWLE VLRVSYEKEI SRLEDKMREF
460 470 480 490 500
PEGVAMEREM RDKWKERVMI GNIKSANRTP EQQDKFKKYK KYDPSKGGDK
510 520 530 540 550
INFGSTKQLG ELLFERMGLE TVIFTDKGAP STNDDSLKFM GSQSDFVKVL
560 570 580 590 600
MEFRKANHLY NNFVSKLSLM IDPDNIVHPS YNIHGTVTGR LSSNEPNAQQ
610 620 630 640 650
FPRKVNTPTL FQYNFEIKKM FNSRFGDGGV IVQFDYSQLE LRILVCYYSR
660 670 680 690 700
PYTIDLYRSG ADLHKAVASD AFGVAIEEVS KDQRTASKKI QFGIVYQESA
710 720 730 740 750
RGLSEDLRAE GITMSEDECE IFIKKYFKRF PKVSKWIRDT KKHVKDISTV
760 770 780 790 800
KTLTGATRNL PDIDSIDQSK ANEAERQAVN TPIQGTGSDC TLMSLILINQ
810 820 830 840 850
WLRESGLRSR ICITVHDSIV LDCPKDEVLE VAKKVKHIME NLGEYNEFYK
860 870 880 890 900
FLGDVPILSE MEIGRNYGDA FEATIEDIEE HGVDGFIEMK EKEKLEKDMK
910 920
EFTKIIEDGG SIPDYARIYW ENIS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M84415 Unassigned DNA Translation: AAA03732.1 Sequence problems. M37686 Genomic DNA Translation: AAA64535.1 |
PIRi | JC1269 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M84415 Unassigned DNA Translation: AAA03732.1 Sequence problems. M37686 Genomic DNA Translation: AAA64535.1 |
PIRi | JC1269 |
3D structure databases
SMRi | P30314 |
ModBasei | Search... |
Proteomic databases
PRIDEi | P30314 |
Family and domain databases
Gene3Di | 3.30.420.10, 1 hit 3.40.470.10, 1 hit |
InterProi | View protein in InterPro IPR002562, 3'-5'_exonuclease_dom IPR019760, DNA-dir_DNA_pol_A_CS IPR001098, DNA-dir_DNA_pol_A_palm_dom IPR043502, DNA/RNA_pol_sf IPR002298, DNA_polymerase_A IPR012337, RNaseH-like_sf IPR036397, RNaseH_sf IPR005122, Uracil-DNA_glycosylase-like IPR036895, Uracil-DNA_glycosylase-like_sf |
PANTHERi | PTHR10133, PTHR10133, 1 hit |
Pfami | View protein in Pfam PF00476, DNA_pol_A, 1 hit PF01612, DNA_pol_A_exo1, 1 hit PF03167, UDG, 1 hit |
PRINTSi | PR00868, DNAPOLI |
SMARTi | View protein in SMART SM00474, 35EXOc, 1 hit SM00482, POLAc, 1 hit |
SUPFAMi | SSF52141, SSF52141, 1 hit SSF53098, SSF53098, 1 hit SSF56672, SSF56672, 1 hit |
PROSITEi | View protein in PROSITE PS00447, DNA_POLYMERASE_A, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | DPOL_BPSP1 | |
Accessioni | P30314Primary (citable) accession number: P30314 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1993 |
Last sequence update: | February 1, 1994 | |
Last modified: | February 23, 2022 | |
This is version 101 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |