UniProtKB - P29515 (TBB7_ARATH)
Protein
Tubulin beta-7 chain
Gene
TUBB7
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
Miscellaneous
There are nine genes coding for beta-tubulin.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 140 – 146 | GTPSequence analysis | 7 |
GO - Molecular functioni
- GTPase activity Source: InterPro
- GTP binding Source: GO_Central
- mRNA binding Source: TAIR
- structural constituent of cytoskeleton Source: TAIR
GO - Biological processi
- microtubule-based process Source: TAIR
- microtubule cytoskeleton organization Source: GO_Central
- mitotic cell cycle Source: GO_Central
- response to cadmium ion Source: TAIR
Keywordsi
Ligand | GTP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Tubulin beta-7 chainAlternative name(s): Beta-7-tubulin |
Gene namesi | Name:TUBB7 Synonyms:TUB7 Ordered Locus Names:At2g29550 ORF Names:F16P2.7 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G29550 |
TAIRi | locus:2043082, AT2G29550 |
Subcellular locationi
Cytoskeleton
Cell Wall
- cell wall Source: TAIR
Cytoskeleton
- microtubule Source: GO_Central
- tubulin complex Source: TAIR
Cytosol
- cytosol Source: TAIR
Golgi apparatus
- Golgi apparatus Source: TAIR
Peroxisome
- peroxisome Source: TAIR
Plasma Membrane
- plasma membrane Source: TAIR
Vacuole
- vacuole Source: TAIR
Other locations
- cytoplasm Source: GO_Central
- plasmodesma Source: TAIR
Keywords - Cellular componenti
Cytoplasm, Cytoskeleton, MicrotubulePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000048326 | 1 – 449 | Tubulin beta-7 chainAdd BLAST | 449 |
Proteomic databases
PaxDbi | P29515 |
PRIDEi | P29515 |
ProteomicsDBi | 234246 |
Expressioni
Gene expression databases
ExpressionAtlasi | P29515, baseline and differential |
Genevisiblei | P29515, AT |
Interactioni
Subunit structurei
Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
Protein-protein interaction databases
BioGRIDi | 2854, 5 interactors |
IntActi | P29515, 1 interactor |
MINTi | P29515 |
STRINGi | 3702.AT2G29550.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the tubulin family.Curated
Phylogenomic databases
eggNOGi | KOG1375, Eukaryota |
HOGENOMi | CLU_015718_1_1_1 |
InParanoidi | P29515 |
OMAi | FWEVVNL |
OrthoDBi | 962471at2759 |
PhylomeDBi | P29515 |
Family and domain databases
Gene3Di | 1.10.287.600, 1 hit 3.30.1330.20, 1 hit 3.40.50.1440, 1 hit |
InterProi | View protein in InterPro IPR013838, Beta-tubulin_BS IPR002453, Beta_tubulin IPR008280, Tub_FtsZ_C IPR000217, Tubulin IPR018316, Tubulin/FtsZ_2-layer-sand-dom IPR037103, Tubulin/FtsZ_C_sf IPR036525, Tubulin/FtsZ_GTPase_sf IPR023123, Tubulin_C IPR017975, Tubulin_CS IPR003008, Tubulin_FtsZ_GTPase |
PANTHERi | PTHR11588, PTHR11588, 1 hit |
Pfami | View protein in Pfam PF00091, Tubulin, 1 hit PF03953, Tubulin_C, 1 hit |
PRINTSi | PR01163, BETATUBULIN PR01161, TUBULIN |
SMARTi | View protein in SMART SM00864, Tubulin, 1 hit SM00865, Tubulin_C, 1 hit |
SUPFAMi | SSF52490, SSF52490, 1 hit SSF55307, SSF55307, 1 hit |
PROSITEi | View protein in PROSITE PS00227, TUBULIN, 1 hit PS00228, TUBULIN_B_AUTOREG, 1 hit |
i Sequence
Sequence statusi: Complete.
P29515-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MREILHIQGG QCGNQIGSKF WEVVNLEHGI DQTGRYVGDS ELQLERVNVY
60 70 80 90 100
YNEASCGRYV PRAVLMDLEP GTMDSVRSGP YGQIFRPDNF VFGQSGAGNN
110 120 130 140 150
WAKGHYTEGA ELIDSVLDVV RKEAENCDCL QGFQVCHSLG GGTGSGMGTL
160 170 180 190 200
LISKIREEYP DRMMMTFSVF PSPKVSDTVV EPYNATLSVH QLVENADECM
210 220 230 240 250
VLDNEALYDI CFRTLKLSTP SFGDLNHLIS ATMSGVTCCL RFPGQLNSDL
260 270 280 290 300
RKLAVNLIPF PRLHFFMVGF APLTSRGSQQ YRNLTVPELT QQMWDAKNMM
310 320 330 340 350
CAADPRHGRY LTASAMFRGK MSTKEVDEQM LNVQNKNSSY FVEWIPNNVK
360 370 380 390 400
STVCDIPPTG LKMASTFIGN STSIQEMFRR VSEQFTAMFR RKAFLHWYTG
410 420 430 440
EGMDEMEFTE AESNMNDLVS EYQQYQDATA DEEGEYEEEE AEYEQEETY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M84704 Genomic DNA Translation: AAA32885.1 AC004561 Genomic DNA Translation: AAC95184.1 CP002685 Genomic DNA Translation: AEC08272.1 AF370568 mRNA Translation: AAK49574.1 AY090345 mRNA Translation: AAL91251.1 BT001121 mRNA Translation: AAN64512.1 AY085710 mRNA Translation: AAM62928.1 |
PIRi | JQ1591 |
RefSeqi | NP_180515.1, NM_128508.3 |
Genome annotation databases
EnsemblPlantsi | AT2G29550.1; AT2G29550.1; AT2G29550 |
GeneIDi | 817504 |
Gramenei | AT2G29550.1; AT2G29550.1; AT2G29550 |
KEGGi | ath:AT2G29550 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M84704 Genomic DNA Translation: AAA32885.1 AC004561 Genomic DNA Translation: AAC95184.1 CP002685 Genomic DNA Translation: AEC08272.1 AF370568 mRNA Translation: AAK49574.1 AY090345 mRNA Translation: AAL91251.1 BT001121 mRNA Translation: AAN64512.1 AY085710 mRNA Translation: AAM62928.1 |
PIRi | JQ1591 |
RefSeqi | NP_180515.1, NM_128508.3 |
3D structure databases
SMRi | P29515 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 2854, 5 interactors |
IntActi | P29515, 1 interactor |
MINTi | P29515 |
STRINGi | 3702.AT2G29550.1 |
Proteomic databases
PaxDbi | P29515 |
PRIDEi | P29515 |
ProteomicsDBi | 234246 |
Genome annotation databases
EnsemblPlantsi | AT2G29550.1; AT2G29550.1; AT2G29550 |
GeneIDi | 817504 |
Gramenei | AT2G29550.1; AT2G29550.1; AT2G29550 |
KEGGi | ath:AT2G29550 |
Organism-specific databases
Araporti | AT2G29550 |
TAIRi | locus:2043082, AT2G29550 |
Phylogenomic databases
eggNOGi | KOG1375, Eukaryota |
HOGENOMi | CLU_015718_1_1_1 |
InParanoidi | P29515 |
OMAi | FWEVVNL |
OrthoDBi | 962471at2759 |
PhylomeDBi | P29515 |
Miscellaneous databases
PROi | PR:P29515 |
Gene expression databases
ExpressionAtlasi | P29515, baseline and differential |
Genevisiblei | P29515, AT |
Family and domain databases
Gene3Di | 1.10.287.600, 1 hit 3.30.1330.20, 1 hit 3.40.50.1440, 1 hit |
InterProi | View protein in InterPro IPR013838, Beta-tubulin_BS IPR002453, Beta_tubulin IPR008280, Tub_FtsZ_C IPR000217, Tubulin IPR018316, Tubulin/FtsZ_2-layer-sand-dom IPR037103, Tubulin/FtsZ_C_sf IPR036525, Tubulin/FtsZ_GTPase_sf IPR023123, Tubulin_C IPR017975, Tubulin_CS IPR003008, Tubulin_FtsZ_GTPase |
PANTHERi | PTHR11588, PTHR11588, 1 hit |
Pfami | View protein in Pfam PF00091, Tubulin, 1 hit PF03953, Tubulin_C, 1 hit |
PRINTSi | PR01163, BETATUBULIN PR01161, TUBULIN |
SMARTi | View protein in SMART SM00864, Tubulin, 1 hit SM00865, Tubulin_C, 1 hit |
SUPFAMi | SSF52490, SSF52490, 1 hit SSF55307, SSF55307, 1 hit |
PROSITEi | View protein in PROSITE PS00227, TUBULIN, 1 hit PS00228, TUBULIN_B_AUTOREG, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TBB7_ARATH | |
Accessioni | P29515Primary (citable) accession number: P29515 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 1, 1993 |
Last sequence update: | April 1, 1993 | |
Last modified: | December 2, 2020 | |
This is version 152 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families