UniProtKB - P29383 (AGL3_ARATH)
Protein
Agamous-like MADS-box protein AGL3
Gene
AGL3
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Probable transcription factor that binds specifically to the CArG box DNA sequence 5'-CC (A/T)6 GG-3' (PubMed:7632923, PubMed:25183521). Plays an important role in the determination of flower meristem identity. Involved in the specification of sepal identity. Contributes to the development of petals, stamens and carpels (PubMed:15530395).3 Publications
GO - Molecular functioni
- DNA-binding transcription factor activity Source: TAIR
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- protein dimerization activity Source: InterPro
- RNA polymerase II transcription regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: GO_Central
- transcription factor binding Source: GO_Central
- transcription regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- carpel development Source: TAIR
- cell differentiation Source: UniProtKB-KW
- maintenance of floral meristem identity Source: TAIR
- petal development Source: TAIR
- positive regulation of transcription by RNA polymerase II Source: InterPro
- sepal development Source: TAIR
- stamen development Source: TAIR
Keywordsi
Molecular function | Developmental protein, DNA-binding |
Biological process | Differentiation, Flowering, Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Agamous-like MADS-box protein AGL3Alternative name(s): Protein SEPALLATA 41 Publication |
Gene namesi | Name:AGL3 Synonyms:SEP41 Publication Ordered Locus Names:At2g03710 ORF Names:F19B11.16 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G03710 |
TAIRi | locus:2044259, AT2G03710 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000199458 | 1 – 258 | Agamous-like MADS-box protein AGL3Add BLAST | 258 |
Proteomic databases
PaxDbi | P29383 |
PRIDEi | P29383 |
ProteomicsDBi | 244886 [P29383-1] |
Expressioni
Tissue specificityi
Expressed in aerial vegetative organs and flowers, but not in roots (PubMed:7632923). Expressed in flower primordia (PubMed:15530395).2 Publications
Gene expression databases
ExpressionAtlasi | P29383, baseline and differential |
Genevisiblei | P29383, AT |
Interactioni
Subunit structurei
Binary interactionsi
P29383
With | #Exp. | IntAct |
---|---|---|
SCL23 [Q9FHZ1] | 3 | EBI-622036,EBI-1238460 |
GO - Molecular functioni
- protein dimerization activity Source: InterPro
- transcription factor binding Source: GO_Central
Protein-protein interaction databases
BioGRIDi | 299, 20 interactors |
DIPi | DIP-33748N |
IntActi | P29383, 19 interactors |
STRINGi | 3702.AT2G03710.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 3 – 57 | MADS-boxPROSITE-ProRule annotationAdd BLAST | 55 | |
Domaini | 88 – 178 | K-boxPROSITE-ProRule annotationAdd BLAST | 91 |
Phylogenomic databases
eggNOGi | KOG0014, Eukaryota |
HOGENOMi | CLU_053053_0_2_1 |
InParanoidi | P29383 |
OMAi | NLQHPRF |
PhylomeDBi | P29383 |
Family and domain databases
CDDi | cd00265, MADS_MEF2_like, 1 hit |
Gene3Di | 3.40.1810.10, 1 hit |
InterProi | View protein in InterPro IPR033896, MADS_MEF2-like IPR002487, TF_Kbox IPR002100, TF_MADSbox IPR036879, TF_MADSbox_sf |
Pfami | View protein in Pfam PF01486, K-box, 1 hit PF00319, SRF-TF, 1 hit |
PRINTSi | PR00404, MADSDOMAIN |
SMARTi | View protein in SMART SM00432, MADS, 1 hit |
SUPFAMi | SSF55455, SSF55455, 1 hit |
PROSITEi | View protein in PROSITE PS51297, K_BOX, 1 hit PS00350, MADS_BOX_1, 1 hit PS50066, MADS_BOX_2, 1 hit |
s (3)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketIsoform 1 (identifier: P29383-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MGRGKVELKR IENKINRQVT FAKRRNGLLK KAYELSVLCD AEIALLIFSN
60 70 80 90 100
RGKLYEFCSS PSGMARTVDK YRKHSYATMD PNQSAKDLQD KYQDYLKLKS
110 120 130 140 150
RVEILQHSQR HLLGEELSEM DVNELEHLER QVDASLRQIR STKARSMLDQ
160 170 180 190 200
LSDLKTKEEM LLETNRDLRR KLEDSDAALT QSFWGSSAAE QQQQHQQQQQ
210 220 230 240 250
GMSSYQSNPP IQEAGFFKPL QGNVALQMSS HYNHNPANAT NSATTSQNVN
GFFPGWMV
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 58 – 92 | Missing (PubMed:1672119).CuratedAdd BLAST | 35 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_008908 | 172 – 258 | LEDSD…PGWMV → VAIGIFYRKKLKPFVI in isoform 2. 1 PublicationAdd BLAST | 87 | |
Alternative sequenceiVSP_041587 | 229 | Missing in isoform 3. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U81369 mRNA Translation: AAB38975.1 AY141229 mRNA Translation: AAN52793.1 AC006836 Genomic DNA Translation: AAD20073.1 CP002685 Genomic DNA Translation: AEC05738.1 CP002685 Genomic DNA Translation: AEC05739.1 CP002685 Genomic DNA Translation: AEC05740.1 AY063894 mRNA Translation: AAL36250.1 AY096386 mRNA Translation: AAM20027.1 |
PIRi | S57793 |
RefSeqi | NP_178466.1, NM_126418.2 [P29383-1] NP_849930.1, NM_179599.2 [P29383-3] NP_973411.1, NM_201682.3 [P29383-2] |
Genome annotation databases
EnsemblPlantsi | AT2G03710.1; AT2G03710.1; AT2G03710 [P29383-1] AT2G03710.2; AT2G03710.2; AT2G03710 [P29383-3] AT2G03710.3; AT2G03710.3; AT2G03710 [P29383-2] |
GeneIDi | 814898 |
Gramenei | AT2G03710.1; AT2G03710.1; AT2G03710 [P29383-1] AT2G03710.2; AT2G03710.2; AT2G03710 [P29383-3] AT2G03710.3; AT2G03710.3; AT2G03710 [P29383-2] |
KEGGi | ath:AT2G03710 |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U81369 mRNA Translation: AAB38975.1 AY141229 mRNA Translation: AAN52793.1 AC006836 Genomic DNA Translation: AAD20073.1 CP002685 Genomic DNA Translation: AEC05738.1 CP002685 Genomic DNA Translation: AEC05739.1 CP002685 Genomic DNA Translation: AEC05740.1 AY063894 mRNA Translation: AAL36250.1 AY096386 mRNA Translation: AAM20027.1 |
PIRi | S57793 |
RefSeqi | NP_178466.1, NM_126418.2 [P29383-1] NP_849930.1, NM_179599.2 [P29383-3] NP_973411.1, NM_201682.3 [P29383-2] |
3D structure databases
SMRi | P29383 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 299, 20 interactors |
DIPi | DIP-33748N |
IntActi | P29383, 19 interactors |
STRINGi | 3702.AT2G03710.1 |
Proteomic databases
PaxDbi | P29383 |
PRIDEi | P29383 |
ProteomicsDBi | 244886 [P29383-1] |
Genome annotation databases
EnsemblPlantsi | AT2G03710.1; AT2G03710.1; AT2G03710 [P29383-1] AT2G03710.2; AT2G03710.2; AT2G03710 [P29383-3] AT2G03710.3; AT2G03710.3; AT2G03710 [P29383-2] |
GeneIDi | 814898 |
Gramenei | AT2G03710.1; AT2G03710.1; AT2G03710 [P29383-1] AT2G03710.2; AT2G03710.2; AT2G03710 [P29383-3] AT2G03710.3; AT2G03710.3; AT2G03710 [P29383-2] |
KEGGi | ath:AT2G03710 |
Organism-specific databases
Araporti | AT2G03710 |
TAIRi | locus:2044259, AT2G03710 |
Phylogenomic databases
eggNOGi | KOG0014, Eukaryota |
HOGENOMi | CLU_053053_0_2_1 |
InParanoidi | P29383 |
OMAi | NLQHPRF |
PhylomeDBi | P29383 |
Miscellaneous databases
PROi | PR:P29383 |
Gene expression databases
ExpressionAtlasi | P29383, baseline and differential |
Genevisiblei | P29383, AT |
Family and domain databases
CDDi | cd00265, MADS_MEF2_like, 1 hit |
Gene3Di | 3.40.1810.10, 1 hit |
InterProi | View protein in InterPro IPR033896, MADS_MEF2-like IPR002487, TF_Kbox IPR002100, TF_MADSbox IPR036879, TF_MADSbox_sf |
Pfami | View protein in Pfam PF01486, K-box, 1 hit PF00319, SRF-TF, 1 hit |
PRINTSi | PR00404, MADSDOMAIN |
SMARTi | View protein in SMART SM00432, MADS, 1 hit |
SUPFAMi | SSF55455, SSF55455, 1 hit |
PROSITEi | View protein in PROSITE PS51297, K_BOX, 1 hit PS00350, MADS_BOX_1, 1 hit PS50066, MADS_BOX_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | AGL3_ARATH | |
Accessioni | P29383Primary (citable) accession number: P29383 Secondary accession number(s): O04729 Q8VZR9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 1, 1992 |
Last sequence update: | December 15, 1998 | |
Last modified: | February 10, 2021 | |
This is version 169 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names