TACR3

Functionⁱ

This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K > substance K > substance P.

GO - Molecular functionⁱ

tachykinin receptor activity
Source: ProtInc
Traceable author statementⁱ
- 8990205

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

aging Source: Ensembl
G-protein coupled receptor signaling pathway Source: Reactome
hyperosmotic salinity response Source: Ensembl
positive regulation of blood pressure Source: Ensembl
positive regulation of flagellated sperm motility
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 17437961
positive regulation of heart rate Source: Ensembl
positive regulation of uterine smooth muscle contraction Source: Ensembl
regulation of dopamine metabolic process Source: Ensembl
regulation of feeding behavior Source: Ensembl
response to cocaine Source: Ensembl
response to estradiol Source: Ensembl
response to morphine Source: Ensembl
tachykinin receptor signaling pathway
Source: ProtInc
Traceable author statementⁱ
- 8990205

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	G-protein coupled receptor, Receptor, Transducer

Molecular function

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

Reactomeⁱ	R-HSA-380095 Tachykinin receptors bind tachykinins R-HSA-416476 G alpha (q) signalling events

Reactomeⁱ

R-HSA-380095 Tachykinin receptors bind tachykinins
R-HSA-416476 G alpha (q) signalling events

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Neuromedin-K receptor Short name: NKR Alternative name(s): NK-3 receptor Short name: NK-3R Neurokinin B receptor Tachykinin receptor 3
Gene namesⁱ	Name:TACR3 Synonyms:NK3R, TAC3R
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 4

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000169836.4
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:11528 TACR3
MIMⁱ	162332 gene
neXtProtⁱ	NX_P29371

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 84	ExtracellularSequence analysisAdd BLAST	84
Transmembraneⁱ	85 – 107	Helical; Name=1Sequence analysisAdd BLAST	23
Topological domainⁱ	108 – 117	CytoplasmicSequence analysis	10
Transmembraneⁱ	118 – 139	Helical; Name=2Sequence analysisAdd BLAST	22
Topological domainⁱ	140 – 159	ExtracellularSequence analysisAdd BLAST	20
Transmembraneⁱ	160 – 181	Helical; Name=3Sequence analysisAdd BLAST	22
Topological domainⁱ	182 – 201	CytoplasmicSequence analysisAdd BLAST	20
Transmembraneⁱ	202 – 222	Helical; Name=4Sequence analysisAdd BLAST	21
Topological domainⁱ	223 – 245	ExtracellularSequence analysisAdd BLAST	23
Transmembraneⁱ	246 – 270	Helical; Name=5Sequence analysisAdd BLAST	25
Topological domainⁱ	271 – 299	CytoplasmicSequence analysisAdd BLAST	29
Transmembraneⁱ	300 – 321	Helical; Name=6Sequence analysisAdd BLAST	22
Topological domainⁱ	322 – 334	ExtracellularSequence analysisAdd BLAST	13
Transmembraneⁱ	335 – 359	Helical; Name=7Sequence analysisAdd BLAST	25
Topological domainⁱ	360 – 465	CytoplasmicSequence analysisAdd BLAST	106

Keywords - Cellular componentⁱ

Cell membrane, Membrane

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Hypogonadotropic hypogonadism 11 with or without anosmia (HH11)3 Publications

The disease is caused by mutations affecting distinct genetic loci, including the gene represented in this entry. The genetics of hypogonadotropic hypogonadism involves various modes of transmission. Oligogenic inheritance has been reported in some patients carrying mutations in TACR3 as well as in other HH-associated genes including FGFR1, SPRY4 and KAL1 (PubMed:23643382).1 Publication

Disease descriptionA disorder characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. In some cases, it is associated with non-reproductive phenotypes, such as anosmia, cleft palate, and sensorineural hearing loss. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. In the presence of anosmia, idiopathic hypogonadotropic hypogonadism is referred to as Kallmann syndrome, whereas in the presence of a normal sense of smell, it has been termed normosmic idiopathic hypogonadotropic hypogonadism (nIHH).

Keywords - Diseaseⁱ

Disease mutation, Hypogonadotropic hypogonadism

Organism-specific databases

DisGeNET More...DisGeNETⁱ	6870
GeneReviewsⁱ	TACR3
MalaCards human disease database More...MalaCardsⁱ	TACR3
MIMⁱ	614840 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000169836
Orphanetⁱ	478 Kallmann syndrome 432 Normosmic congenital hypogonadotropic hypogonadism
PharmGKBⁱ	PA36304

Chemistry databases

ChEMBLⁱ	CHEMBL4429
Drug and drug target database More...DrugBankⁱ	DB04872 Osanetant
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	362

Polymorphism and mutation databases

BioMutaⁱ	TACR3
DMDMⁱ	128364

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000069899	1 – 465	Neuromedin-K receptorAdd BLAST		465

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Glycosylationⁱ	23	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	50	N-linked (GlcNAc...) asparagineSequence analysis	1
Glycosylationⁱ	73	N-linked (GlcNAc...) asparagineSequence analysis	1
Disulfide bondⁱ	158 ↔ 233	PROSITE-ProRule annotation
Lipidationⁱ	374	S-palmitoyl cysteineSequence analysis	1

Post-translational modificationⁱ

The anchoring of this receptor to the plasma membrane is probably mediated by the palmitoylation of a cysteine residue.

Keywords - PTMⁱ

Disulfide bond, Glycoprotein, Lipoprotein, Palmitate

Proteomic databases

PaxDbⁱ	P29371
PRIDEⁱ	P29371
ProteomicsDBⁱ	54552
TopDownProteomicsⁱ	P29371

PTM databases

iPTMnetⁱ	P29371
PhosphoSitePlusⁱ	P29371

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000169836
CleanExⁱ	HS_TACR3
Genevisibleⁱ	P29371 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA009418

HPAⁱ

HPA009418

Interactionⁱ

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
TAC3	Q9UHF0	2	EBI-6655576,EBI-6655626

With

Entry

#Exp.

IntAct

Notes

TAC3

Q9UHF0

2

EBI-6655576,EBI-6655626

Protein-protein interaction databases

BioGridⁱ	112733, 72 interactors
IntActⁱ	P29371, 1 interactor
STRINGⁱ	9606.ENSP00000303325

Chemistry databases

BindingDBⁱ

P29371

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P29371
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG4219 Eukaryota ENOG410XSC5 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000148949
HOGENOMⁱ	HOG000013018
HOVERGENⁱ	HBG103412
InParanoidⁱ	P29371
KEGG Orthology (KO) More...KOⁱ	K04224
OMAⁱ	VMTFAIC
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0WYG
PhylomeDBⁱ	P29371
TreeFamⁱ	TF315303

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR001681 Neurokn_rcpt IPR001013 NK3_rcpt
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR01026 NEUROKININ3R PR00244 NEUROKININR
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P29371-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MATLPAAETW IDGGGGVGAD AVNLTASLAA GAATGAVETG WLQLLDQAGN 
        60         70         80         90        100
LSSSPSALGL PVASPAPSQP WANLTNQFVQ PSWRIALWSL AYGVVVAVAV 
       110        120        130        140        150
LGNLIVIWII LAHKRMRTVT NYFLVNLAFS DASMAAFNTL VNFIYALHSE 
       160        170        180        190        200
WYFGANYCRF QNFFPITAVF ASIYSMTAIA VDRYMAIIDP LKPRLSATAT 
       210        220        230        240        250
KIVIGSIWIL AFLLAFPQCL YSKTKVMPGR TLCFVQWPEG PKQHFTYHII 
       260        270        280        290        300
VIILVYCFPL LIMGITYTIV GITLWGGEIP GDTCDKYHEQ LKAKRKVVKM 
       310        320        330        340        350
MIIVVMTFAI CWLPYHIYFI LTAIYQQLNR WKYIQQVYLA SFWLAMSSTM 
       360        370        380        390        400
YNPIIYCCLN KRFRAGFKRA FRWCPFIKVS SYDELELKTT RFHPNRQSSM 
       410        420        430        440        450
YTVTRMESMT VVFDPNDADT TRSSRKKRAT PRDPSFNGCS RRNSKSASAT 
       460 
SSFISSPYTS VDEYS

Length:465

Mass (Da):52,202

Last modified:December 1, 1992 - v1

Checksum:ⁱ98E88D4BC9DBD315

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	3	T → I in AAB21706 (PubMed:1312036).Curated	1
Sequence conflictⁱ	63	A → R in AAB21706 (PubMed:1312036).Curated	1
Sequence conflictⁱ	439	C → F in CAA46291 (PubMed:1312928).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_069177	93	G → D in HH11; unequivocal evidence of impaired receptor signaling. 1 PublicationCorresponds to variant dbSNP:rs121918124EnsemblClinVar.	1
Natural variantⁱVAR_072976	137	F → V in HH11. 1 Publication	1
Natural variantⁱVAR_049422	286	K → R Polymorphism that may contribute to hypogonadotropic hypogonadism in patients carrying disease-causing mutations in FGFR1. 1 PublicationCorresponds to variant dbSNP:rs2276973EnsemblClinVar.	1
Natural variantⁱVAR_072977	346	M → V in HH11. 1 PublicationCorresponds to variant dbSNP:rs200148989Ensembl.	1
Natural variantⁱVAR_069178	353	P → S in HH11; unequivocal evidence of impaired receptor signaling. 1 PublicationCorresponds to variant dbSNP:rs121918125EnsemblClinVar.	1
Natural variantⁱVAR_069963	364	R → Q in HH11; the patient also carries a mutation in FGFR1. 1 PublicationCorresponds to variant dbSNP:rs150288991Ensembl.	1
Natural variantⁱVAR_049423	449	A → T Polymorphism that may contribute to hypogonadotropic hypogonadism in patients carrying disease-causing mutations in SPRY4 or KAL1. 1 PublicationCorresponds to variant dbSNP:rs17033889EnsemblClinVar.	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M89473 mRNA Translation: AAA36366.1 S86392 , S86371, S86382, S86388, S86390 Genomic DNA Translation: AAB21706.1 X65172 , X65173, X65174, X65175, X65176 Genomic DNA Translation: CAA46291.1 AY462099 mRNA Translation: AAR23926.1 BC121806 mRNA Translation: AAI21807.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS3664.1
PIRⁱ	JQ1517
NCBI Reference Sequences More...RefSeqⁱ	NP_001050.1, NM_001059.2
UniGeneⁱ	Hs.942

Genome annotation databases

Ensemblⁱ	ENST00000304883; ENSP00000303325; ENSG00000169836
GeneIDⁱ	6870
KEGGⁱ	hsa:6870
UCSC genome browser More...UCSCⁱ	uc003hxe.2 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
P29371	Neuromedin-K receptor		RABIT		467
Tachykinin receptor 3		LOXAF		467
UPI00032B1924		OCHPR		467
UPI0003F12715		CHRAS		466
Tachykinin receptor		HUMAN		465
+47

Protein	Similar proteins		Species	Score	Length
P29371	Substance-P receptor		RAT		407
UPI0004BE1FCF		EQUPR		414
UPI0002C65DF5		southern white rhinoceros		412
Tachykinin receptor 1		OTOGA		408
UPI00046BA1C7		EPTFU		407
+272

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	M89473 mRNA Translation: AAA36366.1 S86392 , S86371, S86382, S86388, S86390 Genomic DNA Translation: AAB21706.1 X65172 , X65173, X65174, X65175, X65176 Genomic DNA Translation: CAA46291.1 AY462099 mRNA Translation: AAR23926.1 BC121806 mRNA Translation: AAI21807.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS3664.1
PIRⁱ	JQ1517
NCBI Reference Sequences More...RefSeqⁱ	NP_001050.1, NM_001059.2
UniGeneⁱ	Hs.942

3D structure databases

ProteinModelPortalⁱ	P29371
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	112733, 72 interactors
IntActⁱ	P29371, 1 interactor
STRINGⁱ	9606.ENSP00000303325

Chemistry databases

BindingDBⁱ	P29371
ChEMBLⁱ	CHEMBL4429
Drug and drug target database More...DrugBankⁱ	DB04872 Osanetant
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	362

Protein family/group databases

GPCRDBⁱ	Search...

GPCRDBⁱ

Search...

PTM databases

iPTMnetⁱ	P29371
PhosphoSitePlusⁱ	P29371

Polymorphism and mutation databases

BioMutaⁱ	TACR3
DMDMⁱ	128364

Proteomic databases

PaxDbⁱ	P29371
PRIDEⁱ	P29371
ProteomicsDBⁱ	54552
TopDownProteomicsⁱ	P29371

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000304883; ENSP00000303325; ENSG00000169836
GeneIDⁱ	6870
KEGGⁱ	hsa:6870
UCSC genome browser More...UCSCⁱ	uc003hxe.2 human

Organism-specific databases

CTDⁱ	6870
DisGeNET More...DisGeNETⁱ	6870
EuPathDBⁱ	HostDB:ENSG00000169836.4
GeneCardsⁱ	TACR3
GeneReviewsⁱ	TACR3
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:11528 TACR3
Human Protein Atlas More...HPAⁱ	HPA009418
MalaCards human disease database More...MalaCardsⁱ	TACR3
MIMⁱ	162332 gene 614840 phenotype
neXtProtⁱ	NX_P29371
Open Targets More...OpenTargetsⁱ	ENSG00000169836
Orphanetⁱ	478 Kallmann syndrome 432 Normosmic congenital hypogonadotropic hypogonadism
PharmGKBⁱ	PA36304
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG4219 Eukaryota ENOG410XSC5 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00920000148949
HOGENOMⁱ	HOG000013018
HOVERGENⁱ	HBG103412
InParanoidⁱ	P29371
KEGG Orthology (KO) More...KOⁱ	K04224
OMAⁱ	VMTFAIC
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0WYG
PhylomeDBⁱ	P29371
TreeFamⁱ	TF315303

Enzyme and pathway databases

Reactomeⁱ	R-HSA-380095 Tachykinin receptors bind tachykinins R-HSA-416476 G alpha (q) signalling events

Reactomeⁱ

R-HSA-380095 Tachykinin receptors bind tachykinins
R-HSA-416476 G alpha (q) signalling events

Miscellaneous databases

GeneWikiⁱ	Tachykinin_receptor_3
GenomeRNAiⁱ	6870
Protein Ontology More...PROⁱ	PR:P29371
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000169836
CleanExⁱ	HS_TACR3
Genevisibleⁱ	P29371 HS

Family and domain databases

InterProⁱ	View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR001681 Neurokn_rcpt IPR001013 NK3_rcpt
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00001 7tm_1, 1 hit
PRINTSⁱ	PR00237 GPCRRHODOPSN PR01026 NEUROKININ3R PR00244 NEUROKININR
PROSITEⁱ	View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	NK3R_HUMAN
Accessionⁱ	P29371Primary (citable) accession number: P29371 Secondary accession number(s): Q0P510
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
	Last sequence update:	December 1, 1992
	Last modified:	June 20, 2018
	This is version 154 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries
Human chromosome 4
Human chromosome 4: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
SIMILARITY comments
Index of protein domains and families

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UniProtKB - P29371 (NK3R_HUMAN)

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Neuromedin-K receptor

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Plasma membrane

Nucleus

Plasma Membrane

Other locations

Topology

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ