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Protein

Protein BMH1

Gene

BMH1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in growth regulation.

Miscellaneous

Present with 158000 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • DNA replication origin binding Source: SGD
  • phosphoserine residue binding Source: SGD
  • protein domain specific binding Source: InterPro
  • RNA polymerase II activating transcription factor binding Source: SGD

GO - Biological processi

Enzyme and pathway databases

BioCyciYEAST:G3O-30336-MONOMER
ReactomeiR-SCE-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-SCE-3371453 Regulation of HSF1-mediated heat shock response
R-SCE-3371511 HSF1 activation
R-SCE-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
R-SCE-5625740 RHO GTPases activate PKNs
R-SCE-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
R-SCE-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex

Names & Taxonomyi

Protein namesi
Recommended name:
Protein BMH1
Gene namesi
Name:BMH1
Ordered Locus Names:YER177W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome V

Organism-specific databases

EuPathDBiFungiDB:YER177W
SGDiS000000979 BMH1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000587152 – 267Protein BMH1Add BLAST266

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserine1 Publication1
Cross-linki76Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)Combined sources
Modified residuei89PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQBiP29311
PaxDbiP29311
PRIDEiP29311
TopDownProteomicsiP29311

2D gel databases

COMPLUYEAST-2DPAGEiP29311
SWISS-2DPAGEiP29311

PTM databases

iPTMnetiP29311

Interactioni

Subunit structurei

Interacts with FIN1.1 Publication

Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

BioGridi36930, 486 interactors
DIPiDIP-4313N
IntActiP29311, 139 interactors
MINTiP29311
STRINGi4932.YER177W

Structurei

Secondary structure

1267
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP29311
SMRiP29311
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 14-3-3 family.Curated

Phylogenomic databases

GeneTreeiENSGT00760000119116
HOGENOMiHOG000240379
InParanoidiP29311
KOiK06630
OMAiKKQQMGR
OrthoDBiEOG092C46UY

Family and domain databases

Gene3Di1.20.190.20, 1 hit
InterProiView protein in InterPro
IPR000308 14-3-3
IPR023409 14-3-3_CS
IPR036815 14-3-3_dom_sf
IPR023410 14-3-3_domain
PANTHERiPTHR18860 PTHR18860, 1 hit
PfamiView protein in Pfam
PF00244 14-3-3, 1 hit
PIRSFiPIRSF000868 14-3-3, 1 hit
PRINTSiPR00305 1433ZETA
SMARTiView protein in SMART
SM00101 14_3_3, 1 hit
SUPFAMiSSF48445 SSF48445, 1 hit
PROSITEiView protein in PROSITE
PS00796 1433_1, 1 hit
PS00797 1433_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P29311-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSTSREDSVY LAKLAEQAER YEEMVENMKT VASSGQELSV EERNLLSVAY
60 70 80 90 100
KNVIGARRAS WRIVSSIEQK EESKEKSEHQ VELICSYRSK IETELTKISD
110 120 130 140 150
DILSVLDSHL IPSATTGESK VFYYKMKGDY HRYLAEFSSG DAREKATNAS
160 170 180 190 200
LEAYKTASEI ATTELPPTHP IRLGLALNFS VFYYEIQNSP DKACHLAKQA
210 220 230 240 250
FDDAIAELDT LSEESYKDST LIMQLLRDNL TLWTSDMSES GQAEDQQQQQ
260
QHQQQQPPAA AEGEAPK
Length:267
Mass (Da):30,091
Last modified:January 23, 2007 - v4
Checksum:i0A234167E313688B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti197A → R in CAA50656 (PubMed:1378790).Curated1
Sequence conflicti197A → R in CAA46959 (Ref. 2) Curated1
Sequence conflicti263 – 267GEAPK → VKHQSKYSDKSKEKLLKKRK KKERGCNNL in CAA50656 (PubMed:1378790).Curated5

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X71664 Genomic DNA Translation: CAA50656.1
X66206 Genomic DNA Translation: CAA46959.1
U18922 Genomic DNA Translation: AAB64704.1
BK006939 Genomic DNA Translation: DAA07840.1
PIRiS30863
RefSeqiNP_011104.3, NM_001179067.3

Genome annotation databases

EnsemblFungiiYER177W; YER177W; YER177W
GeneIDi856924
KEGGisce:YER177W

Similar proteinsi

Entry informationi

Entry nameiBMH1_YEAST
AccessioniPrimary (citable) accession number: P29311
Secondary accession number(s): D3DM86, Q06854
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: January 23, 2007
Last modified: September 12, 2018
This is version 180 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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