UniProtKB - P29311 (BMH1_YEAST)
Protein
Protein BMH1
Gene
BMH1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
Involved in growth regulation.
Miscellaneous
Present with 158000 molecules/cell in log phase SD medium.1 Publication
GO - Molecular functioni
- DNA replication origin binding Source: SGD
- phosphoserine residue binding Source: SGD
- RNA polymerase II activating transcription factor binding Source: SGD
GO - Biological processi
- aggresome assembly Source: SGD
- ascospore formation Source: SGD
- DNA damage checkpoint Source: SGD
- fungal-type cell wall chitin biosynthetic process Source: SGD
- mitotic spindle orientation checkpoint Source: SGD
- negative regulation of apoptotic process Source: SGD
- negative regulation of transcription by RNA polymerase II Source: SGD
- negative regulation of ubiquitin protein ligase activity Source: SGD
- pseudohyphal growth Source: SGD
- Ras protein signal transduction Source: SGD
- regulation of glycogen metabolic process Source: SGD
- signal transduction involved in filamentous growth Source: SGD
Names & Taxonomyi
Protein namesi | Recommended name: Protein BMH1 |
Gene namesi | Name:BMH1 Ordered Locus Names:YER177W |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:YER177W |
SGDi | S000000979, BMH1 |
Subcellular locationi
Nucleus
- nucleus Source: SGD
Plasma Membrane
- plasma membrane Source: SGD
Other locations
- cytoplasm Source: SGD
- cytoplasmic stress granule Source: SGD
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed1 Publication | |||
ChainiPRO_0000058715 | 2 – 267 | Protein BMH1Add BLAST | 266 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 2 | N-acetylserine1 Publication | 1 | |
Cross-linki | 76 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)Combined sources | ||
Modified residuei | 89 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
MaxQBi | P29311 |
PaxDbi | P29311 |
PRIDEi | P29311 |
TopDownProteomicsi | P29311 |
2D gel databases
COMPLUYEAST-2DPAGEi | P29311 |
SWISS-2DPAGEi | P29311 |
PTM databases
iPTMneti | P29311 |
Interactioni
Subunit structurei
Interacts with FIN1.
1 PublicationBinary interactionsi
Hide detailsP29311
With | #Exp. | IntAct |
---|---|---|
BMH2 [P34730] | 7 | EBI-3661,EBI-3672 |
NTH1 [P32356] | 7 | EBI-3661,EBI-19509 |
AKT1S1 [Q96B36] from Homo sapiens. | 3 | EBI-3661,EBI-720593 |
GO - Molecular functioni
- phosphoserine residue binding Source: SGD
- RNA polymerase II activating transcription factor binding Source: SGD
Protein-protein interaction databases
BioGRIDi | 36930, 671 interactors |
DIPi | DIP-4313N |
IntActi | P29311, 141 interactors |
MINTi | P29311 |
STRINGi | 4932.YER177W |
Miscellaneous databases
RNActi | P29311, protein |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P29311 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the 14-3-3 family.Curated
Phylogenomic databases
eggNOGi | KOG0841, Eukaryota |
GeneTreei | ENSGT01010000222256 |
HOGENOMi | CLU_058290_0_0_1 |
InParanoidi | P29311 |
OMAi | PPTDPMR |
Family and domain databases
Gene3Di | 1.20.190.20, 1 hit |
InterProi | View protein in InterPro IPR000308, 14-3-3 IPR023409, 14-3-3_CS IPR036815, 14-3-3_dom_sf IPR023410, 14-3-3_domain |
PANTHERi | PTHR18860, PTHR18860, 1 hit |
Pfami | View protein in Pfam PF00244, 14-3-3, 1 hit |
PIRSFi | PIRSF000868, 14-3-3, 1 hit |
PRINTSi | PR00305, 1433ZETA |
SMARTi | View protein in SMART SM00101, 14_3_3, 1 hit |
SUPFAMi | SSF48445, SSF48445, 1 hit |
PROSITEi | View protein in PROSITE PS00796, 1433_1, 1 hit PS00797, 1433_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P29311-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTSREDSVY LAKLAEQAER YEEMVENMKT VASSGQELSV EERNLLSVAY
60 70 80 90 100
KNVIGARRAS WRIVSSIEQK EESKEKSEHQ VELICSYRSK IETELTKISD
110 120 130 140 150
DILSVLDSHL IPSATTGESK VFYYKMKGDY HRYLAEFSSG DAREKATNAS
160 170 180 190 200
LEAYKTASEI ATTELPPTHP IRLGLALNFS VFYYEIQNSP DKACHLAKQA
210 220 230 240 250
FDDAIAELDT LSEESYKDST LIMQLLRDNL TLWTSDMSES GQAEDQQQQQ
260
QHQQQQPPAA AEGEAPK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 197 | A → R in CAA50656 (PubMed:1378790).Curated | 1 | |
Sequence conflicti | 197 | A → R in CAA46959 (Ref. 2) Curated | 1 | |
Sequence conflicti | 263 – 267 | GEAPK → VKHQSKYSDKSKEKLLKKRK KKERGCNNL in CAA50656 (PubMed:1378790).Curated | 5 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X71664 Genomic DNA Translation: CAA50656.1 X66206 Genomic DNA Translation: CAA46959.1 U18922 Genomic DNA Translation: AAB64704.1 BK006939 Genomic DNA Translation: DAA07840.1 |
PIRi | S30863 |
RefSeqi | NP_011104.3, NM_001179067.3 |
Genome annotation databases
EnsemblFungii | YER177W_mRNA; YER177W; YER177W |
GeneIDi | 856924 |
KEGGi | sce:YER177W |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X71664 Genomic DNA Translation: CAA50656.1 X66206 Genomic DNA Translation: CAA46959.1 U18922 Genomic DNA Translation: AAB64704.1 BK006939 Genomic DNA Translation: DAA07840.1 |
PIRi | S30863 |
RefSeqi | NP_011104.3, NM_001179067.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5N6N | X-ray | 2.29 | A/B | 1-236 | [»] | |
6QK8 | X-ray | 2.92 | A/B/C/D | 1-236 | [»] | |
SMRi | P29311 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 36930, 671 interactors |
DIPi | DIP-4313N |
IntActi | P29311, 141 interactors |
MINTi | P29311 |
STRINGi | 4932.YER177W |
PTM databases
iPTMneti | P29311 |
2D gel databases
COMPLUYEAST-2DPAGEi | P29311 |
SWISS-2DPAGEi | P29311 |
Proteomic databases
MaxQBi | P29311 |
PaxDbi | P29311 |
PRIDEi | P29311 |
TopDownProteomicsi | P29311 |
Genome annotation databases
EnsemblFungii | YER177W_mRNA; YER177W; YER177W |
GeneIDi | 856924 |
KEGGi | sce:YER177W |
Organism-specific databases
EuPathDBi | FungiDB:YER177W |
SGDi | S000000979, BMH1 |
Phylogenomic databases
eggNOGi | KOG0841, Eukaryota |
GeneTreei | ENSGT01010000222256 |
HOGENOMi | CLU_058290_0_0_1 |
InParanoidi | P29311 |
OMAi | PPTDPMR |
Miscellaneous databases
PROi | PR:P29311 |
RNActi | P29311, protein |
Family and domain databases
Gene3Di | 1.20.190.20, 1 hit |
InterProi | View protein in InterPro IPR000308, 14-3-3 IPR023409, 14-3-3_CS IPR036815, 14-3-3_dom_sf IPR023410, 14-3-3_domain |
PANTHERi | PTHR18860, PTHR18860, 1 hit |
Pfami | View protein in Pfam PF00244, 14-3-3, 1 hit |
PIRSFi | PIRSF000868, 14-3-3, 1 hit |
PRINTSi | PR00305, 1433ZETA |
SMARTi | View protein in SMART SM00101, 14_3_3, 1 hit |
SUPFAMi | SSF48445, SSF48445, 1 hit |
PROSITEi | View protein in PROSITE PS00796, 1433_1, 1 hit PS00797, 1433_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | BMH1_YEAST | |
Accessioni | P29311Primary (citable) accession number: P29311 Secondary accession number(s): D3DM86, Q06854 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 1, 1992 |
Last sequence update: | January 23, 2007 | |
Last modified: | December 2, 2020 | |
This is version 198 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Yeast chromosome V
Yeast (Saccharomyces cerevisiae) chromosome V: entries and gene names - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD