CPN60I

Functionⁱ

Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.

GO - Molecular functionⁱ

ATPase binding
Source: AgBase
Inferred from physical interactionⁱ
- 1973526
ATP binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

protein folding
Source: AgBase
Traceable author statementⁱ
- 1973526
protein refolding Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Chaperone
Biological process	Stress response
Ligand	ATP-binding, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Chaperonin CPN60-1, mitochondrial Alternative name(s): HSP60-1
Gene namesⁱ	Name:CPN60I Synonyms:CPNA
Organismⁱ	Zea mays (Maize)
Taxonomic identifierⁱ	4577 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Mesangiospermae › Liliopsida › Petrosaviidae › commelinids › Poales › Poaceae › PACMAD clade › Panicoideae › Andropogonodae › Andropogoneae › Tripsacinae › Zea
Proteomesⁱ	UP000007305 Componentⁱ: Chromosome 5

Organism-specific databases

MaizeGDBⁱ	65669

MaizeGDBⁱ

65669

Keywords - Cellular componentⁱ

Mitochondrion

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transit peptideⁱ	1 – 34	Mitochondrion1 PublicationAdd BLAST		34
ChainⁱPRO_0000005014	35 – 577	Chaperonin CPN60-1, mitochondrialAdd BLAST		543

Proteomic databases

PRIDEⁱ	P29185

PRIDEⁱ

P29185

Expressionⁱ

Inductionⁱ

By heat shock.

Gene expression databases

ExpressionAtlasⁱ	P29185 differential

ExpressionAtlasⁱ

P29185 differential

Interactionⁱ

GO - Molecular functionⁱ

ATPase binding
Source: AgBase
Inferred from physical interactionⁱ
- 1973526

View the complete GO annotation on QuickGO ...

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P29185
SMRⁱ	P29185
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the chaperonin (HSP60) family.Curated

Keywords - Domainⁱ

Transit peptide

Phylogenomic databases

eggNOGⁱ	KOG0356 Eukaryota COG0459 LUCA
HOGENOMⁱ	HOG000076290
KEGG Orthology (KO) More...KOⁱ	K04077

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03344 GroEL, 1 hit
Gene3Dⁱ	1.10.560.10, 2 hits 3.30.260.10, 2 hits 3.50.7.10, 1 hit
HAMAPⁱ	MF_00600 CH60, 1 hit
InterProⁱ	View protein in InterPro IPR018370 Chaperonin_Cpn60_CS IPR001844 Chaprnin_Cpn60 IPR002423 Cpn60/TCP-1 IPR027409 GroEL-like_apical_dom_sf IPR027413 GROEL-like_equatorial_sf IPR027410 TCP-1-like_intermed_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00118 Cpn60_TCP1, 1 hit
PRINTSⁱ	PR00298 CHAPERONIN60
SUPFAMⁱ	SSF48592 SSF48592, 2 hits SSF52029 SSF52029, 1 hit SSF54849 SSF54849, 1 hit
TIGRFAMsⁱ	TIGR02348 GroEL, 1 hit
PROSITEⁱ	View protein in PROSITE PS00296 CHAPERONINS_CPN60, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P29185-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MYRAAASLAS KARQAGNSLA TRQVGSRLAW SRNYAAKDIK FGVEARALML 
        60         70         80         90        100
RGVEELADAV KVTMGPKGRN VVIEQSFGAP KVTKDGVTVA KSIEFKDRVK 
       110        120        130        140        150
NVGASLVKQV ANATNDTAGD GTTCATVLTK AIFTEGCKSV AAGMNAMDLR 
       160        170        180        190        200
RGISMAVDAV VTNLKGMARM ISTSEEIAQV GTISANGERE IGELIAKAME 
       210        220        230        240        250
KVGKEGVITI ADGNTLYNEL EVVEGMKLDR GYISPYFITN SKTQKCELED 
       260        270        280        290        300
PLILIHDKKV TNMHAVVKVL EMALKKQKPL LIVAEDVESE ALGTLIINKL 
       310        320        330        340        350
RAGIKVCAVK APGFGENRKA NLQDLAILTG GEVITEELGM NLENFEPHML 
       360        370        380        390        400
GTCKKVTVSK DDTVILDGAG DKKSIEERAE QIRSAIENST SDYDKEKLQE 
       410        420        430        440        450
RLAKLSGGVA VLKIGGASEA EVGEKKDRVT DALNATKAAV EEGIVPGGGV 
       460        470        480        490        500
ALLYASKELD KLQTANFDQK IGVQIIQNAL KTPVHTIASN AGVEGAVVVG 
       510        520        530        540        550
KLLEQENTDL GYDAAKGEYV DMVKTGIIDP LKVIRTALVD AASVSSLMTT 
       560        570 
TESIIVEIPK EEAPAPAMGG GMGGMDY

Length:577

Mass (Da):61,211

Last modified:November 1, 1997 - v2

Checksum:ⁱ31D3BFFD46701C0B

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	21	T → A in CAA78100 (Ref. 3) Curated	1
Sequence conflictⁱ	108 – 109	KQ → NR in CAA77645 (PubMed:1349837).Curated	2
Sequence conflictⁱ	125	A → D in CAA77645 (PubMed:1349837).Curated	1
Sequence conflictⁱ	148	D → N in CAA77645 (PubMed:1349837).Curated	1
Sequence conflictⁱ	241	S → P in CAA78100 (Ref. 3) Curated	1
Sequence conflictⁱ	328	L → F in CAA77645 (PubMed:1349837).Curated	1
Sequence conflictⁱ	382	I → L in CAA77645 (PubMed:1349837).Curated	1
Sequence conflictⁱ	403	A → P in AAA33450 (Ref. 2) Curated	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Z11546 mRNA Translation: CAA77645.1 L21007 Genomic DNA Translation: AAA33450.1 Z12114 mRNA Translation: CAA78100.1
PIRⁱ	S20875 S26582
NCBI Reference Sequences More...RefSeqⁱ	NP_001105716.1, NM_001112246.1
UniGeneⁱ	Zm.2489

Genome annotation databases

EnsemblPlantsⁱ	Zm00001d014090_T001; Zm00001d014090_P001; Zm00001d014090 Zm00001d014090_T002; Zm00001d014090_P002; Zm00001d014090
GeneIDⁱ	542736
Grameneⁱ	Zm00001d014090_T001; Zm00001d014090_P001; Zm00001d014090 Zm00001d014090_T002; Zm00001d014090_P002; Zm00001d014090
KEGGⁱ	zma:542736

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length
P29185	Chaperonin 1		MAIZE		577
Uncharacterized protein		MAIZE		352

Protein	Similar proteins		Species	Score	Length
P29185	Chaperonin 1		MAIZE		577
Uncharacterized protein		ORYNI		677
Chaperonin CPN60-1, mitochondrial, putative, expressed		ORYSJ		577
Uncharacterized protein		ORYGL		577
Uncharacterized protein		ORYSI		577
+31

Protein	Similar proteins		Species	Score	Length
P29185	Chaperonin 1		MAIZE		577
Uncharacterized protein		ORYNI		677
Chaperonin CPN60-1, mitochondrial, putative, expressed		ORYSJ		577
Uncharacterized protein		ORYGL		577
Uncharacterized protein		ORYSI		577
+32

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Z11546 mRNA Translation: CAA77645.1 L21007 Genomic DNA Translation: AAA33450.1 Z12114 mRNA Translation: CAA78100.1
PIRⁱ	S20875 S26582
NCBI Reference Sequences More...RefSeqⁱ	NP_001105716.1, NM_001112246.1
UniGeneⁱ	Zm.2489

3D structure databases

ProteinModelPortalⁱ	P29185
SMRⁱ	P29185
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Proteomic databases

PRIDEⁱ	P29185

PRIDEⁱ

P29185

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblPlantsⁱ	Zm00001d014090_T001; Zm00001d014090_P001; Zm00001d014090 Zm00001d014090_T002; Zm00001d014090_P002; Zm00001d014090
GeneIDⁱ	542736
Grameneⁱ	Zm00001d014090_T001; Zm00001d014090_P001; Zm00001d014090 Zm00001d014090_T002; Zm00001d014090_P002; Zm00001d014090
KEGGⁱ	zma:542736

Organism-specific databases

MaizeGDBⁱ	65669

MaizeGDBⁱ

65669

Phylogenomic databases

eggNOGⁱ	KOG0356 Eukaryota COG0459 LUCA
HOGENOMⁱ	HOG000076290
KEGG Orthology (KO) More...KOⁱ	K04077

Gene expression databases

ExpressionAtlasⁱ	P29185 differential

ExpressionAtlasⁱ

P29185 differential

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd03344 GroEL, 1 hit
Gene3Dⁱ	1.10.560.10, 2 hits 3.30.260.10, 2 hits 3.50.7.10, 1 hit
HAMAPⁱ	MF_00600 CH60, 1 hit
InterProⁱ	View protein in InterPro IPR018370 Chaperonin_Cpn60_CS IPR001844 Chaprnin_Cpn60 IPR002423 Cpn60/TCP-1 IPR027409 GroEL-like_apical_dom_sf IPR027413 GROEL-like_equatorial_sf IPR027410 TCP-1-like_intermed_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00118 Cpn60_TCP1, 1 hit
PRINTSⁱ	PR00298 CHAPERONIN60
SUPFAMⁱ	SSF48592 SSF48592, 2 hits SSF52029 SSF52029, 1 hit SSF54849 SSF54849, 1 hit
TIGRFAMsⁱ	TIGR02348 GroEL, 1 hit
PROSITEⁱ	View protein in PROSITE PS00296 CHAPERONINS_CPN60, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CH61_MAIZE
Accessionⁱ	P29185Primary (citable) accession number: P29185 Secondary accession number(s): Q43251, Q43252
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
	Last sequence update:	November 1, 1997
	Last modified:	May 23, 2018
	This is version 108 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Plant Protein Annotation Program

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P29185 (CH61_MAIZE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

Chaperonin CPN60-1, mitochondrial

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Mitochondrion

Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ