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UniProtKB - P29185 (CH61_MAIZE)
Protein
Chaperonin CPN60-1, mitochondrial
Gene
CPN60I
Organism
Zea mays (Maize)
Status
Functioni
Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
GO - Molecular functioni
- ATPase binding Source: AgBase
- ATP binding Source: UniProtKB-KW
- ATP hydrolysis activity Source: InterPro
GO - Biological processi
- protein folding Source: GO_Central
- protein refolding Source: InterPro
Keywordsi
Molecular function | Chaperone |
Biological process | Stress response |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Chaperonin CPN60-1, mitochondrialAlternative name(s): HSP60-1 |
Gene namesi | Name:CPN60I Synonyms:CPNA |
Organismi | Zea mays (Maize) |
Taxonomic identifieri | 4577 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › PACMAD clade › Panicoideae › Andropogonodae › Andropogoneae › Tripsacinae › Zea |
Proteomesi |
|
Organism-specific databases
MaizeGDBi | 65669 |
Subcellular locationi
Mitochondrion
Mitochondrion
- mitochondrial matrix Source: AgBase
- mitochondrion Source: GO_Central
Keywords - Cellular componenti
MitochondrionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 34 | Mitochondrion1 PublicationAdd BLAST | 34 | |
ChainiPRO_0000005014 | 35 – 577 | Chaperonin CPN60-1, mitochondrialAdd BLAST | 543 |
Proteomic databases
PRIDEi | P29185 |
Expressioni
Inductioni
By heat shock.
Gene expression databases
ExpressionAtlasi | P29185, baseline and differential |
Family & Domainsi
Sequence similaritiesi
Belongs to the chaperonin (HSP60) family.Curated
Keywords - Domaini
Transit peptidePhylogenomic databases
OMAi | TDTDKME |
OrthoDBi | 415781at2759 |
Family and domain databases
CDDi | cd03344, GroEL, 1 hit |
Gene3Di | 1.10.560.10, 1 hit 3.30.260.10, 1 hit 3.50.7.10, 1 hit |
HAMAPi | MF_00600, CH60, 1 hit |
InterProi | View protein in InterPro IPR018370, Chaperonin_Cpn60_CS IPR001844, Chaprnin_Cpn60 IPR002423, Cpn60/TCP-1 IPR027409, GroEL-like_apical_dom_sf IPR027413, GROEL-like_equatorial_sf IPR027410, TCP-1-like_intermed_sf |
Pfami | View protein in Pfam PF00118, Cpn60_TCP1, 1 hit |
PRINTSi | PR00298, CHAPERONIN60 |
SUPFAMi | SSF48592, SSF48592, 1 hit SSF52029, SSF52029, 1 hit SSF54849, SSF54849, 1 hit |
TIGRFAMsi | TIGR02348, GroEL, 1 hit |
PROSITEi | View protein in PROSITE PS00296, CHAPERONINS_CPN60, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
P29185-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MYRAAASLAS KARQAGNSLA TRQVGSRLAW SRNYAAKDIK FGVEARALML
60 70 80 90 100
RGVEELADAV KVTMGPKGRN VVIEQSFGAP KVTKDGVTVA KSIEFKDRVK
110 120 130 140 150
NVGASLVKQV ANATNDTAGD GTTCATVLTK AIFTEGCKSV AAGMNAMDLR
160 170 180 190 200
RGISMAVDAV VTNLKGMARM ISTSEEIAQV GTISANGERE IGELIAKAME
210 220 230 240 250
KVGKEGVITI ADGNTLYNEL EVVEGMKLDR GYISPYFITN SKTQKCELED
260 270 280 290 300
PLILIHDKKV TNMHAVVKVL EMALKKQKPL LIVAEDVESE ALGTLIINKL
310 320 330 340 350
RAGIKVCAVK APGFGENRKA NLQDLAILTG GEVITEELGM NLENFEPHML
360 370 380 390 400
GTCKKVTVSK DDTVILDGAG DKKSIEERAE QIRSAIENST SDYDKEKLQE
410 420 430 440 450
RLAKLSGGVA VLKIGGASEA EVGEKKDRVT DALNATKAAV EEGIVPGGGV
460 470 480 490 500
ALLYASKELD KLQTANFDQK IGVQIIQNAL KTPVHTIASN AGVEGAVVVG
510 520 530 540 550
KLLEQENTDL GYDAAKGEYV DMVKTGIIDP LKVIRTALVD AASVSSLMTT
560 570
TESIIVEIPK EEAPAPAMGG GMGGMDY
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A804PAZ7 | A0A804PAZ7_MAIZE | Uncharacterized protein | 542736 | 473 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 21 | T → A in CAA78100 (Ref. 3) Curated | 1 | |
Sequence conflicti | 108 – 109 | KQ → NR in CAA77645 (PubMed:1349837).Curated | 2 | |
Sequence conflicti | 125 | A → D in CAA77645 (PubMed:1349837).Curated | 1 | |
Sequence conflicti | 148 | D → N in CAA77645 (PubMed:1349837).Curated | 1 | |
Sequence conflicti | 241 | S → P in CAA78100 (Ref. 3) Curated | 1 | |
Sequence conflicti | 328 | L → F in CAA77645 (PubMed:1349837).Curated | 1 | |
Sequence conflicti | 382 | I → L in CAA77645 (PubMed:1349837).Curated | 1 | |
Sequence conflicti | 403 | A → P in AAA33450 (Ref. 2) Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z11546 mRNA Translation: CAA77645.1 L21007 Genomic DNA Translation: AAA33450.1 Z12114 mRNA Translation: CAA78100.1 |
PIRi | S20875 S26582 |
RefSeqi | NP_001105716.1, NM_001112246.1 |
Genome annotation databases
EnsemblPlantsi | Zm00001eb222300_T002; Zm00001eb222300_P002; Zm00001eb222300 |
GeneIDi | 542736 |
Gramenei | Zm00001eb222300_T002; Zm00001eb222300_P002; Zm00001eb222300 |
KEGGi | zma:542736 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z11546 mRNA Translation: CAA77645.1 L21007 Genomic DNA Translation: AAA33450.1 Z12114 mRNA Translation: CAA78100.1 |
PIRi | S20875 S26582 |
RefSeqi | NP_001105716.1, NM_001112246.1 |
3D structure databases
SMRi | P29185 |
ModBasei | Search... |
Proteomic databases
PRIDEi | P29185 |
Genome annotation databases
EnsemblPlantsi | Zm00001eb222300_T002; Zm00001eb222300_P002; Zm00001eb222300 |
GeneIDi | 542736 |
Gramenei | Zm00001eb222300_T002; Zm00001eb222300_P002; Zm00001eb222300 |
KEGGi | zma:542736 |
Organism-specific databases
MaizeGDBi | 65669 |
Phylogenomic databases
OMAi | TDTDKME |
OrthoDBi | 415781at2759 |
Gene expression databases
ExpressionAtlasi | P29185, baseline and differential |
Family and domain databases
CDDi | cd03344, GroEL, 1 hit |
Gene3Di | 1.10.560.10, 1 hit 3.30.260.10, 1 hit 3.50.7.10, 1 hit |
HAMAPi | MF_00600, CH60, 1 hit |
InterProi | View protein in InterPro IPR018370, Chaperonin_Cpn60_CS IPR001844, Chaprnin_Cpn60 IPR002423, Cpn60/TCP-1 IPR027409, GroEL-like_apical_dom_sf IPR027413, GROEL-like_equatorial_sf IPR027410, TCP-1-like_intermed_sf |
Pfami | View protein in Pfam PF00118, Cpn60_TCP1, 1 hit |
PRINTSi | PR00298, CHAPERONIN60 |
SUPFAMi | SSF48592, SSF48592, 1 hit SSF52029, SSF52029, 1 hit SSF54849, SSF54849, 1 hit |
TIGRFAMsi | TIGR02348, GroEL, 1 hit |
PROSITEi | View protein in PROSITE PS00296, CHAPERONINS_CPN60, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CH61_MAIZE | |
Accessioni | P29185Primary (citable) accession number: P29185 Secondary accession number(s): Q43251, Q43252 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 1, 1992 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 23, 2022 | |
This is version 122 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families