UniProtKB - P28704 (RXRB_MOUSE)

BLAST

>sp|P28704|RXRB_MOUSE Retinoic acid receptor RXR-beta OS=Mus musculus OX=10090 GN=Rxrb PE=1 SV=2
MSWATRPPFLPPRHAAGQCGPVGVRKEMHCGVASRWRRRRPWLDPAAAAAAAGEQQALEP
EPGEAGRDGMGDSGRDSRSPDSSSPNPLSQGIRPSSPPGPPLTPSAPPPPMPPPPLGSPF
PVISSSMGSPGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPP
PPGGPGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQ
RNRCQYCRYQKCLATGMKREAVQEERQRGKDKDGDGDGAGGAPEEMPVDRILEAELAVEQ
KSDQGVEGPGATGGGGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVILLR
AGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMRM
DKTELGCLRAIILFNPDAKGLSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRL
PALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQLA

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History
Entry version 183 (07 Nov 2018)
Sequence version 2 (01 Feb 1996)
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Protein

Retinoic acid receptor RXR-beta

Gene

Rxrb

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).2 Publications

Regions

Feature key	Position(s)	DescriptionActions	Length
DNA bindingⁱ	192 – 257	Nuclear receptorPROSITE-ProRule annotationAdd BLAST	66
Zinc fingerⁱ	192 – 212	NR C4-typePROSITE-ProRule annotationAdd BLAST	21
Zinc fingerⁱ	228 – 252	NR C4-typePROSITE-ProRule annotationAdd BLAST	25

GO - Molecular functionⁱ

9-cis retinoic acid receptor activity
Source: MGI
Inferred from direct assayⁱ
- 1312497
DNA-binding transcription activator activity, RNA polymerase II-specific Source: MGI
nuclear receptor activity Source: MGI
protein heterodimerization activity Source: MGI
protein homodimerization activity
Source: MGI
Inferred from direct assayⁱ
- 7831303
retinoic acid receptor binding Source: MGI
RNA polymerase II distal enhancer sequence-specific DNA binding
Source: MGI
Inferred from direct assayⁱ
- 2554307
RNA polymerase II regulatory region sequence-specific DNA binding
Source: MGI
Inferred from direct assayⁱ
- 7831303
sequence-specific DNA binding
Source: MGI
Inferred from genetic interactionⁱ
- 7823919
steroid hormone receptor activity Source: InterPro
thyroid hormone receptor binding Source: MGI
thyroid hormone receptor coactivator activity Source: MGI
transcription regulatory region DNA binding
Source: UniProtKB
Inferred from direct assayⁱ
- 18922886
vitamin D receptor binding Source: MGI
zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cardiac muscle cell proliferation
Source: MGI
Inferred from genetic interactionⁱ
- 9428411
cellular response to retinoic acid
Source: UniProtKB
Inferred from direct assayⁱ
- 18922886
in utero embryonic development
Source: MGI
Inferred from genetic interactionⁱ
- 9892670
maternal placenta development
Source: MGI
Inferred from genetic interactionⁱ
- 9892670
positive regulation of transcription by RNA polymerase II
Source: MGI
Inferred from genetic interactionⁱ
- 7823919
regulation of myelination Source: MGI
retinoic acid receptor signaling pathway
Source: MGI
Inferred from direct assayⁱ
- 1312497
ventricular cardiac muscle cell differentiation
Source: MGI
Inferred from mutant phenotypeⁱ
- 9428411

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding, Receptor
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Enzyme and pathway databases

Reactomeⁱ	R-MMU-383280 Nuclear Receptor transcription pathway R-MMU-5362517 Signaling by Retinoic Acid

Reactomeⁱ

R-MMU-383280 Nuclear Receptor transcription pathway
R-MMU-5362517 Signaling by Retinoic Acid

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Retinoic acid receptor RXR-beta Alternative name(s): MHC class I regulatory element-binding protein H-2RIIBP Nuclear receptor subfamily 2 group B member 2 Retinoid X receptor beta
Gene namesⁱ	Name:Rxrb Synonyms:Nr2b2
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 17

Organism-specific databases

MGIⁱ	MGI:98215 Rxrb

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Chemistry databases

ChEMBLⁱ	CHEMBL4047
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	611

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000053573	1 – 520	Retinoic acid receptor RXR-betaAdd BLAST		520

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	25	Omega-N-methylarginineBy similarity		1

Keywords - PTMⁱ

Methylation

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	P28704
PaxDbⁱ	P28704
PeptideAtlas More...PeptideAtlasⁱ	P28704
PRIDEⁱ	P28704

PTM databases

iPTMnetⁱ	P28704
PhosphoSitePlusⁱ	P28704

Expressionⁱ

Tissue specificityⁱ

In all tissues tested, including brain, thymus, spleen and liver.2 Publications

Gene expression databases

Bgeeⁱ	ENSMUSG00000039656 Expressed in 306 organ(s), highest expression level in embryo
CleanExⁱ	MM_RXRB
ExpressionAtlasⁱ	P28704 baseline and differential
Genevisibleⁱ	P28704 MM

Interactionⁱ

Subunit structureⁱ

GO - Molecular functionⁱ

protein heterodimerization activity Source: MGI
protein homodimerization activity
Source: MGI
Inferred from direct assayⁱ
- 7831303
retinoic acid receptor binding Source: MGI
thyroid hormone receptor binding Source: MGI
vitamin D receptor binding Source: MGI

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	203039, 2 interactors
ComplexPortalⁱ	CPX-706 RXRbeta-LXRbeta nuclear hormone receptor complex CPX-717 RXRbeta-LXRalpha nuclear hormone receptor complex CPX-872 RXRbeta-VDR nuclear hormone receptor complex
IntActⁱ	P28704, 1 interactor
STRINGⁱ	10090.ENSMUSP00000036585

Chemistry databases

BindingDBⁱ

P28704

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P28704
SMRⁱ	P28704
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	283 – 516	NR LBDPROSITE-ProRule annotationAdd BLAST		234

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	1 – 191	ModulatingBy similarityAdd BLAST		191
Regionⁱ	258 – 382	HingeAdd BLAST		125

Domainⁱ

Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.1 Publication

Sequence similaritiesⁱ

Belongs to the nuclear hormone receptor family. NR2 subfamily.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	192 – 212	NR C4-typePROSITE-ProRule annotationAdd BLAST		21
Zinc fingerⁱ	228 – 252	NR C4-typePROSITE-ProRule annotationAdd BLAST		25

Keywords - Domainⁱ

Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG3575 Eukaryota ENOG410XRZC LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118948
HOGENOMⁱ	HOG000260821
HOVERGENⁱ	HBG005606
InParanoidⁱ	P28704
KEGG Orthology (KO) More...KOⁱ	K08525
OMAⁱ	KMNDRSV
PhylomeDBⁱ	P28704

Family and domain databases

Gene3Dⁱ	3.30.50.10, 1 hit
InterProⁱ	View protein in InterPro IPR035500 NHR_like_dom_sf IPR000536 Nucl_hrmn_rcpt_lig-bd IPR001723 Nuclear_hrmn_rcpt IPR000003 Retinoid-X_rcpt/HNF4 IPR001628 Znf_hrmn_rcpt IPR013088 Znf_NHR/GATA
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00104 Hormone_recep, 1 hit PF00105 zf-C4, 1 hit
PRINTSⁱ	PR00545 RETINOIDXR PR00398 STRDHORMONER PR00047 STROIDFINGER
SMARTⁱ	View protein in SMART SM00430 HOLI, 1 hit SM00399 ZnF_C4, 1 hit
SUPFAMⁱ	SSF48508 SSF48508, 1 hit
PROSITEⁱ	View protein in PROSITE PS51843 NR_LBD, 1 hit PS00031 NUCLEAR_REC_DBD_1, 1 hit PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

Note: Additional isoforms seem to exist.

This entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show all Align All

Isoform Long (identifier: P28704-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSWATRPPFL PPRHAAGQCG PVGVRKEMHC GVASRWRRRR PWLDPAAAAA 
        60         70         80         90        100
AAGEQQALEP EPGEAGRDGM GDSGRDSRSP DSSSPNPLSQ GIRPSSPPGP 
       110        120        130        140        150
PLTPSAPPPP MPPPPLGSPF PVISSSMGSP GLPPPAPPGF SGPVSSPQIN 
       160        170        180        190        200
STVSLPGGGS GPPEDVKPPV LGVRGLHCPP PPGGPGAGKR LCAICGDRSS 
       210        220        230        240        250
GKHYGVYSCE GCKGFFKRTI RKDLTYSCRD NKDCTVDKRQ RNRCQYCRYQ 
       260        270        280        290        300
KCLATGMKRE AVQEERQRGK DKDGDGDGAG GAPEEMPVDR ILEAELAVEQ 
       310        320        330        340        350
KSDQGVEGPG ATGGGGSSPN DPVTNICQAA DKQLFTLVEW AKRIPHFSSL 
       360        370        380        390        400
PLDDQVILLR AGWNELLIAS FSHRSIDVRD GILLATGLHV HRNSAHSAGV 
       410        420        430        440        450
GAIFDRVLTE LVSKMRDMRM DKTELGCLRA IILFNPDAKG LSNPGEVEIL 
       460        470        480        490        500
REKVYASLET YCKQKYPEQQ GRFAKLLLRL PALRSIGLKC LEHLFFFKLI 
       510        520
GDTPIDTFLM EMLEAPHQLA

Length:520

Mass (Da):55,866

Last modified:February 1, 1996 - v2

Checksum:ⁱ71FAEAEC0D2DB505

Isoform Short (identifier: P28704-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-110: Missing.

« Hide

        10         20         30         40         50
MPPPPLGSPF PVISSSMGSP GLPPPAPPGF SGPVSSPQIN STVSLPGGGS 
        60         70         80         90        100
GPPEDVKPPV LGVRGLHCPP PPGGPGAGKR LCAICGDRSS GKHYGVYSCE 
       110        120        130        140        150
GCKGFFKRTI RKDLTYSCRD NKDCTVDKRQ RNRCQYCRYQ KCLATGMKRE 
       160        170        180        190        200
AVQEERQRGK DKDGDGDGAG GAPEEMPVDR ILEAELAVEQ KSDQGVEGPG 
       210        220        230        240        250
ATGGGGSSPN DPVTNICQAA DKQLFTLVEW AKRIPHFSSL PLDDQVILLR 
       260        270        280        290        300
AGWNELLIAS FSHRSIDVRD GILLATGLHV HRNSAHSAGV GAIFDRVLTE 
       310        320        330        340        350
LVSKMRDMRM DKTELGCLRA IILFNPDAKG LSNPGEVEIL REKVYASLET 
       360        370        380        390        400
YCKQKYPEQQ GRFAKLLLRL PALRSIGLKC LEHLFFFKLI GDTPIDTFLM 
       410
EMLEAPHQLA

Show »

Length:410

Mass (Da):44,396

Checksum:ⁱ76353141EEA68AB0

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q3TWJ1	Q3TWJ1_MOUSE	Retinoic acid receptor RXR-beta Retinoic acid receptor RXR-beta	Rxrb	524	Annotation score:
Q8VCR0	Q8VCR0_MOUSE	Retinoic acid receptor RXR-beta Retinoic acid receptor RXR-beta (Rxrb protein)	Rxrb	414	Annotation score:
G3UXP8	G3UXP8_MOUSE	Retinoic acid receptor RXR-beta Retinoic acid receptor RXR-beta	Rxrb	459	Annotation score:
G3UZ09	G3UZ09_MOUSE	Retinoic acid receptor RXR-beta Retinoic acid receptor RXR-beta	Rxrb	150	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	73 – 75	SGR → MGP in AAA40081 (PubMed:1310259).Curated	3
Sequence conflictⁱ	75 – 77	RDS → EFP in AAA37772 (PubMed:2554307).Curated	3
Sequence conflictⁱ	433	L → M in AAA40081 (PubMed:1310259).Curated	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_003678	1 – 110	Missing in isoform Short. CuratedAdd BLAST		110

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D21831 Genomic DNA Translation: BAA04858.1 D21831 Genomic DNA Translation: BAA04859.1 AF100956 Genomic DNA Translation: AAC69904.1 BC049773 mRNA Translation: AAH49773.1 M84818 mRNA Translation: AAA40081.2 M26804 mRNA Translation: AAA37772.1 X66224 mRNA Translation: CAA46963.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS57068.1 [P28704-2]
PIRⁱ	A34418 D41727 I84718 S26669
NCBI Reference Sequences More...RefSeqⁱ	NP_001192145.1, NM_001205216.1 [P28704-2] NP_035436.1, NM_011306.4 [P28704-1]
UniGeneⁱ	Mm.1243

Genome annotation databases

Ensemblⁱ	ENSMUST00000116612; ENSMUSP00000112311; ENSMUSG00000039656 [P28704-2]
GeneIDⁱ	20182
KEGGⁱ	mmu:20182
UCSC genome browser More...UCSCⁱ	uc008cax.2 mouse [P28704-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
P28704	Retinoic acid receptor RXR-beta	)	HUMAN		533	UniRef90_P28702
Retinoic acid receptor RXR-beta		CANLF		533
RXRB isoform 1		PANTR		533
Uncharacterized protein		PAPAN		533
Uncharacterized protein		RHIRO		542
+216

Protein	Similar proteins		Species	Score	Length	Source
P28704	Retinoic acid receptor RXR-beta	)	HUMAN		533	UniRef50_P28702
Retinoic acid receptor RXR-beta		CANLF		533
RXRB isoform 1		PANTR		533
Uncharacterized protein		PAPAN		533
Uncharacterized protein		RHIRO		542
+337

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D21831 Genomic DNA Translation: BAA04858.1 D21831 Genomic DNA Translation: BAA04859.1 AF100956 Genomic DNA Translation: AAC69904.1 BC049773 mRNA Translation: AAH49773.1 M84818 mRNA Translation: AAA40081.2 M26804 mRNA Translation: AAA37772.1 X66224 mRNA Translation: CAA46963.1
CCDSⁱ	CCDS57068.1 [P28704-2]
PIRⁱ	A34418 D41727 I84718 S26669
RefSeqⁱ	NP_001192145.1, NM_001205216.1 [P28704-2] NP_035436.1, NM_011306.4 [P28704-1]
UniGeneⁱ	Mm.1243

3D structure databases

ProteinModelPortalⁱ	P28704
SMRⁱ	P28704
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	203039, 2 interactors
ComplexPortalⁱ	CPX-706 RXRbeta-LXRbeta nuclear hormone receptor complex CPX-717 RXRbeta-LXRalpha nuclear hormone receptor complex CPX-872 RXRbeta-VDR nuclear hormone receptor complex
IntActⁱ	P28704, 1 interactor
STRINGⁱ	10090.ENSMUSP00000036585

Chemistry databases

BindingDBⁱ	P28704
ChEMBLⁱ	CHEMBL4047
GuidetoPHARMACOLOGYⁱ	611

PTM databases

iPTMnetⁱ	P28704
PhosphoSitePlusⁱ	P28704

Proteomic databases

MaxQBⁱ	P28704
PaxDbⁱ	P28704
PeptideAtlasⁱ	P28704
PRIDEⁱ	P28704

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000116612; ENSMUSP00000112311; ENSMUSG00000039656 [P28704-2]
GeneIDⁱ	20182
KEGGⁱ	mmu:20182
UCSCⁱ	uc008cax.2 mouse [P28704-1]

Organism-specific databases

CTDⁱ	6257
MGIⁱ	MGI:98215 Rxrb

Phylogenomic databases

eggNOGⁱ	KOG3575 Eukaryota ENOG410XRZC LUCA
GeneTreeⁱ	ENSGT00760000118948
HOGENOMⁱ	HOG000260821
HOVERGENⁱ	HBG005606
InParanoidⁱ	P28704
KOⁱ	K08525
OMAⁱ	KMNDRSV
PhylomeDBⁱ	P28704

Enzyme and pathway databases

Reactomeⁱ	R-MMU-383280 Nuclear Receptor transcription pathway R-MMU-5362517 Signaling by Retinoic Acid

Reactomeⁱ

R-MMU-383280 Nuclear Receptor transcription pathway
R-MMU-5362517 Signaling by Retinoic Acid

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:P28704
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000039656 Expressed in 306 organ(s), highest expression level in embryo
CleanExⁱ	MM_RXRB
ExpressionAtlasⁱ	P28704 baseline and differential
Genevisibleⁱ	P28704 MM

Family and domain databases

Gene3Dⁱ	3.30.50.10, 1 hit
InterProⁱ	View protein in InterPro IPR035500 NHR_like_dom_sf IPR000536 Nucl_hrmn_rcpt_lig-bd IPR001723 Nuclear_hrmn_rcpt IPR000003 Retinoid-X_rcpt/HNF4 IPR001628 Znf_hrmn_rcpt IPR013088 Znf_NHR/GATA
Pfamⁱ	View protein in Pfam PF00104 Hormone_recep, 1 hit PF00105 zf-C4, 1 hit
PRINTSⁱ	PR00545 RETINOIDXR PR00398 STRDHORMONER PR00047 STROIDFINGER
SMARTⁱ	View protein in SMART SM00430 HOLI, 1 hit SM00399 ZnF_C4, 1 hit
SUPFAMⁱ	SSF48508 SSF48508, 1 hit
PROSITEⁱ	View protein in PROSITE PS51843 NR_LBD, 1 hit PS00031 NUCLEAR_REC_DBD_1, 1 hit PS51030 NUCLEAR_REC_DBD_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RXRB_MOUSE
Accessionⁱ	P28704Primary (citable) accession number: P28704 Secondary accession number(s): P33243
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
	Last sequence update:	February 1, 1996
	Last modified:	November 7, 2018
	This is version 183 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P28704 (RXRB_MOUSE)

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Retinoic acid receptor RXR-beta

Rxrb

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ