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Entry version 153 (16 Oct 2019)
Sequence version 3 (09 Jan 2007)
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Protein

Murinoglobulin-1

Gene

Mug1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

A proteinase activates the inhibitor by specific proteolysis in the bait region, which, by an unknown mechanism leads to reaction at the cysteinyl-glutamyl internal thiol ester site and to a conformational change, whereby the proteinase is trapped and/or covalently bound to the inhibitor. While in the tetrameric proteinase inhibitors steric inhibition is sufficiently strong, monomeric forms need a covalent linkage between the activated glutamyl residue of the original thiol ester and a terminal amino group of a lysine or another nucleophilic group on the proteinase, for inhibition to be effective.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

  • embryo implantation Source: MGI

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPS protease database

More...
MEROPSi
I39.004

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Murinoglobulin-1
Short name:
MuG1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mug1
Synonyms:Mug-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:99837 Mug1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 271 PublicationAdd BLAST27
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000005928 – 1476Murinoglobulin-1Add BLAST1449

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi48 ↔ 86By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi55N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi251 ↔ 276By similarity
Disulfide bondi269 ↔ 288By similarity
Glycosylationi294N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi313N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi461 ↔ 555By similarity
Glycosylationi500N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi587 ↔ 773By similarity
Disulfide bondi634 ↔ 680By similarity
Glycosylationi749N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi776N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi849 ↔ 885By similarity
Glycosylationi871N-linked (GlcNAc...) asparagine1 Publication1
Disulfide bondi923 ↔ 1323By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki974 ↔ 977Isoglutamyl cysteine thioester (Cys-Gln)By similarity
Glycosylationi993N-linked (GlcNAc...) asparagine2 Publications1
Disulfide bondi1081 ↔ 1129By similarity
Glycosylationi1142N-linked (GlcNAc...) asparagine2 Publications1
Glycosylationi1180N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1354 ↔ 1469By similarity
Glycosylationi1426N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein, Thioester bond

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
non-CPTAC-3658

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
P28665

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P28665

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P28665

PeptideAtlas

More...
PeptideAtlasi
P28665

PRoteomics IDEntifications database

More...
PRIDEi
P28665

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
P28665

GlyConnect protein glycosylation platform

More...
GlyConnecti
747

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P28665

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P28665

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P28665

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Plasma.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000059908 Expressed in 17 organ(s), highest expression level in liver

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P28665 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Monomer.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
201613, 1 interactor

Protein interaction database and analysis system

More...
IntActi
P28665, 3 interactors

Molecular INTeraction database

More...
MINTi
P28665

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000032228

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni677 – 734Bait regionAdd BLAST58

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Bait region, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IMYI Eukaryota
COG2373 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164557

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000220939

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P28665

Identification of Orthologs from Complete Genome Data

More...
OMAi
QLLYKHD

Database of Orthologous Groups

More...
OrthoDBi
354230at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P28665

TreeFam database of animal gene trees

More...
TreeFami
TF313285

Family and domain databases

Conserved Domains Database

More...
CDDi
cd02897 A2M_2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 2 hits
2.60.40.690, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009048 A-macroglobulin_rcpt-bd
IPR036595 A-macroglobulin_rcpt-bd_sf
IPR011625 A2M_N_BRD
IPR041813 A2M_TED
IPR011626 Alpha-macroglobulin_TED
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR001599 Macroglobln_a2
IPR019742 MacrogloblnA2_CS
IPR002890 MG2
IPR041555 MG3
IPR040839 MG4
IPR008930 Terpenoid_cyclase/PrenylTrfase
IPR010916 TonB_box_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00207 A2M, 1 hit
PF07703 A2M_BRD, 1 hit
PF07677 A2M_recep, 1 hit
PF01835 MG2, 1 hit
PF17791 MG3, 1 hit
PF17789 MG4, 1 hit
PF07678 TED_complement, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01360 A2M, 1 hit
SM01359 A2M_N_2, 1 hit
SM01361 A2M_recep, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48239 SSF48239, 1 hit
SSF49410 SSF49410, 1 hit
SSF81296 SSF81296, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00477 ALPHA_2_MACROGLOBULIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P28665-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWKSRRAQLC LFSVLLAFLH SASLLNGDSK YMVLVPSQLY TETPEKICLH
60 70 80 90 100
LYQLNETVTV TASLVSQSGR KNLFDELVLD KDLFQCVSFI IPRLSSSDEE
110 120 130 140 150
DFLYVDIKGP THEFSKRKAV LVKNKESVVF VQTDKPVYKP GQSVKFRVVS
160 170 180 190 200
MDKMLRPLNE LLPLAYIEDP KKNRIMQWRD IKTENGLKQM SFSLAAEPIQ
210 220 230 240 250
GPYKIVVHKE SGEKEEHSFT VMEFVLPRFN VDLKVPNAMS VNDEVLSVTA
260 270 280 290 300
CGKYTYGKPV PGHVKINVCR ETETGCREVN SQLDNNGCST QEVNITELQS
310 320 330 340 350
KKRNYEVQLF HVNATVTEEG TGLEFSRSGT TKIERITNKL IFLKADSHFR
360 370 380 390 400
HGIPFFVKVR LVDIKGDPIP NEKVFIKAQE LSYTSATTTD QHGLAEFSID
410 420 430 440 450
TTCISGSSLH IKVNHKEEDS CSYFYCMEER HASAKHVAYA VYSLSKSYIY
460 470 480 490 500
LDTETSSILP CNQIHTVQAH FILKGDLGVL KELIFYYLVM AQGSIIQTGN
510 520 530 540 550
HTHQVEPGEA PVKGKFALEI PVEFSMVPMA KMLIYTILPD GEVIADSVNF
560 570 580 590 600
EIEKCLRNKV DLRFSTSQSL PASQTRLQVT ASPQSLCGLR AVDQSVLLLK
610 620 630 640 650
PESELSPSWI YNLPGMQQNK FVPSSRLSED QEDCILYSSW LAEKHTNLVP
660 670 680 690 700
HGTEKDVYRY VEDMGLTAFT NLMIKLPIIC FDYGMVPISA PRVEFDLAFT
710 720 730 740 750
PEISWSLRTT LSKRPEEPPR KDPSSNDPLT ETIRKYFPET WVWDIVTVNS
760 770 780 790 800
TGLAEVEMTV PDTITEWKAG ALCLSNDTGL GLSSVVPLQA FKPFFVEVSL
810 820 830 840 850
PYSVVRGEAF MLKATVMNYL PTSMQMSVQL EASPDFTAVP VGDDQDSYCL
860 870 880 890 900
SANGRHTSSW LVTPKSLGNV NFSVSAEAQQ SSEPCGSEVA TVPETGRKDT
910 920 930 940 950
VVKVLIVEPE GIKQEHTFSS LFCASDAEIS EKMSLVLPPT VVKDSARAHF
960 970 980 990 1000
SVMGDILSSA IRNTQNLLHM PYGCGEQNMV LFAPNIYVLK YLNETQQLTQ
1010 1020 1030 1040 1050
KIKTKALGFL RAGYQRELNY KHKDGSYSAF GDQNGEREGN TWLTAFVLKS
1060 1070 1080 1090 1100
FAQARAFIFI DESHITHAFT WLSQKQKDNG CFRSSGSLFN NAMKGGVDDE
1110 1120 1130 1140 1150
MTLSAYITMA LLESSLPATH PVVSKALSCL ESSWKTIEQE RNASFVYTKA
1160 1170 1180 1190 1200
LMAYAFALAG NQNKRDEILK SLDEEAIKEN NSIHWKRPQK SRKSEHHLYK
1210 1220 1230 1240 1250
PQASSAEVEM NAYVVLARLT AQPAPSPEDL TLSMSTIMWL TKQQNSNGGF
1260 1270 1280 1290 1300
SSTQDTVVAL DALSKYGAVT FSRSQKTTLV TIQSTGSFSQ KFQVENSNRL
1310 1320 1330 1340 1350
LLQQVALPDI PGDYTISVSG EGCVYAQTML RYNMHLEKQL SAFAIWVQTV
1360 1370 1380 1390 1400
PLTCNNPKGH NSFQISLEIS YTGSRPASNM VIADVKMLSG FIPLKPTVKK
1410 1420 1430 1440 1450
LERLEHVSRT EVSNNNVLIY LDQVTNQTLA FSFIIQQDIP VRNLQPAIVK
1460 1470
VYDYYETDEM AFAEYSSPCS TDKQNV
Length:1,476
Mass (Da):165,298
Last modified:January 9, 2007 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAA43460E473096E1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti894E → A in AAA73048 (PubMed:1840592).Curated1
Sequence conflicti935 – 937LVL → SGP in AAA73048 (PubMed:1840592).Curated3
Sequence conflicti967L → P in AAA73048 (PubMed:1840592).Curated1
Sequence conflicti1034N → S in BAE25800 (PubMed:16141072).Curated1
Sequence conflicti1407V → E in BAE25800 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M65736 mRNA Translation: AAA73048.1
AK144255 mRNA Translation: BAE25800.1
AK144541 mRNA Translation: BAE25930.1
BC051037 mRNA Translation: AAH51037.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS39618.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A41185

NCBI Reference Sequences

More...
RefSeqi
NP_032671.2, NM_008645.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000032228; ENSMUSP00000032228; ENSMUSG00000059908

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
17836

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:17836

UCSC genome browser

More...
UCSCi
uc009dor.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M65736 mRNA Translation: AAA73048.1
AK144255 mRNA Translation: BAE25800.1
AK144541 mRNA Translation: BAE25930.1
BC051037 mRNA Translation: AAH51037.1
CCDSiCCDS39618.1
PIRiA41185
RefSeqiNP_032671.2, NM_008645.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi201613, 1 interactor
IntActiP28665, 3 interactors
MINTiP28665
STRINGi10090.ENSMUSP00000032228

Protein family/group databases

MEROPSiI39.004

PTM databases

CarbonylDBiP28665
GlyConnecti747
iPTMnetiP28665
PhosphoSitePlusiP28665
SwissPalmiP28665

Proteomic databases

CPTACinon-CPTAC-3658
jPOSTiP28665
MaxQBiP28665
PaxDbiP28665
PeptideAtlasiP28665
PRIDEiP28665

Genome annotation databases

EnsembliENSMUST00000032228; ENSMUSP00000032228; ENSMUSG00000059908
GeneIDi17836
KEGGimmu:17836
UCSCiuc009dor.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
17836
MGIiMGI:99837 Mug1

Phylogenomic databases

eggNOGiENOG410IMYI Eukaryota
COG2373 LUCA
GeneTreeiENSGT00940000164557
HOGENOMiHOG000220939
InParanoidiP28665
OMAiQLLYKHD
OrthoDBi354230at2759
PhylomeDBiP28665
TreeFamiTF313285

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Mug1 mouse

Protein Ontology

More...
PROi
PR:P28665

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000059908 Expressed in 17 organ(s), highest expression level in liver
GenevisibleiP28665 MM

Family and domain databases

CDDicd02897 A2M_2, 1 hit
Gene3Di2.60.40.10, 2 hits
2.60.40.690, 1 hit
InterProiView protein in InterPro
IPR009048 A-macroglobulin_rcpt-bd
IPR036595 A-macroglobulin_rcpt-bd_sf
IPR011625 A2M_N_BRD
IPR041813 A2M_TED
IPR011626 Alpha-macroglobulin_TED
IPR013783 Ig-like_fold
IPR014756 Ig_E-set
IPR001599 Macroglobln_a2
IPR019742 MacrogloblnA2_CS
IPR002890 MG2
IPR041555 MG3
IPR040839 MG4
IPR008930 Terpenoid_cyclase/PrenylTrfase
IPR010916 TonB_box_CS
PfamiView protein in Pfam
PF00207 A2M, 1 hit
PF07703 A2M_BRD, 1 hit
PF07677 A2M_recep, 1 hit
PF01835 MG2, 1 hit
PF17791 MG3, 1 hit
PF17789 MG4, 1 hit
PF07678 TED_complement, 1 hit
SMARTiView protein in SMART
SM01360 A2M, 1 hit
SM01359 A2M_N_2, 1 hit
SM01361 A2M_recep, 1 hit
SUPFAMiSSF48239 SSF48239, 1 hit
SSF49410 SSF49410, 1 hit
SSF81296 SSF81296, 1 hit
PROSITEiView protein in PROSITE
PS00477 ALPHA_2_MACROGLOBULIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMUG1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P28665
Secondary accession number(s): Q3UNE7, Q80XE6
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: January 9, 2007
Last modified: October 16, 2019
This is version 153 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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