UniProtKB - P28366 (SECA_BACSU)

BLAST

>sp|P28366|SECA_BACSU Protein translocase subunit SecA OS=Bacillus subtilis (strain 168) OX=224308 GN=secA PE=1 SV=1
MLGILNKMFDPTKRTLNRYEKIANDIDAIRGDYENLSDDALKHKTIEFKERLEKGATTDD
LLVEAFAVVREASRRVTGMFPFKVQLMGGVALHDGNIAEMKTGEGKTLTSTLPVYLNALT
GKGVHVVTVNEYLASRDAEQMGKIFEFLGLTVGLNLNSMSKDEKREAYAADITYSTNNEL
GFDYLRDNMVLYKEQMVQRPLHFAVIDEVDSILIDEARTPLIISGQAAKSTKLYVQANAF
VRTLKAEKDYTYDIKTKAVQLTEEGMTKAEKAFGIDNLFDVKHVALNHHINQALKAHVAM
QKDVDYVVEDGQVVIVDSFTGRLMKGRRYSEGLHQAIEAKEGLEIQNESMTLATITFQNY
FRMYEKLAGMTGTAKTEEEEFRNIYNMQVVTIPTNRPVVRDDRPDLIYRTMEGKFKAVAE
DVAQRYMTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGAV
TIATNMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLS
MEDELMRRFGAERTMAMLDRFGMDDSTPIQSKMVSRAVESSQKRVEGNNFDSRKQLLQYD
DVLRQQREVIYKQRFEVIDSENLREIVENMIKSSLERAIAAYTPREELPEEWKLDGLVDL
INTTYLDEGALEKSDIFGKEPDEMLELIMDRIITKYNEKEEQFGKEQMREFEKVIVLRAV
DSKWMDHIDAMDQLRQGIHLRAYAQTNPLREYQMEGFAMFEHMIESIEDEVAKFVMKAEI
ENNLEREEVVQGQTTAHQPQEGDDNKKAKKAPVRKVVDIGRNAPCHCGSGKKYKNCCGRT
E

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History
Entry version 160 (10 Oct 2018)
Sequence version 1 (01 Dec 1992)
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Protein

Protein translocase subunit SecA

Gene

secA

Organism

Bacillus subtilis (strain 168)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.UniRule annotation

Cofactorⁱ

Zn²⁺UniRule annotationNote: May bind 1 zinc ion per subunit.UniRule annotation

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	825	ZincUniRule annotation	1
Metal bindingⁱ	827	ZincUniRule annotation	1
Metal bindingⁱ	836	ZincUniRule annotation	1
Metal bindingⁱ	837	ZincUniRule annotation	1

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	100 – 107	ATPUniRule annotation		8

GO - Molecular functionⁱ

ATPase-coupled protein transmembrane transporter activity Source: GO_Central
ATP binding Source: GO_Central
metal ion binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

intracellular protein transmembrane transport Source: UniProtKB-UniRule
protein import Source: InterPro
protein targeting Source: UniProtKB-UniRule
protein transport by the Sec complex Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Biological process	Protein transport, Translocation, Transport
Ligand	ATP-binding, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCycⁱ	BSUB:BSU35300-MONOMER
BRENDAⁱ	3.6.3.B1 658

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Protein translocase subunit SecAUniRule annotation
Gene namesⁱ	Name:secAUniRule annotation Synonyms:div+ Ordered Locus Names:BSU35300
Organismⁱ	Bacillus subtilis (strain 168)
Taxonomic identifierⁱ	224308 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus subtilis group › Bacillus subtilis › Bacillus subtilis subsp. subtilis
Proteomesⁱ	UP000001570 Componentⁱ: Chromosome

Subcellular locationⁱ

Cell membrane
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_01382
; Peripheral membrane protein
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_01382
; Cytoplasmic side
UniRule annotation
Manual assertion according to rulesⁱ
- HAMAP-Rule:MF_01382
Cytoplasm

Note:

Distribution is 50-50.UniRule annotation

GO - Cellular componentⁱ

cell envelope Sec protein transport complex Source: GO_Central
cytosol Source: GO_Central
integral component of plasma membrane Source: GO_Central

View the complete GO annotation on QuickGO ...

Keywords - Cellular componentⁱ

Cell membrane, Cytoplasm, Membrane

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Length
Mutagenesisⁱ	587	G → C: Forms position 587-750 dimers upon oxidation in vitro; when associated with C-750. Does not form position 587-587 dimers (homodimers). 1 Publication	1
Mutagenesisⁱ	588	N → C: Forms position 588-588 dimers upon oxidation in vitro (homodimers). 1 Publication	1
Mutagenesisⁱ	750	R → C: Forms position 587-750 dimers upon oxidation in vitro; when associated with C-587. Also forms position 750-750 dimers (homodimers). 1 Publication	1

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000109576	1 – 841	Protein translocase subunit SecAAdd BLAST		841

Proteomic databases

PaxDbⁱ	P28366
PRIDEⁱ	P28366

Interactionⁱ

Subunit structureⁱ

Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may be involved. Monomer and many different homodimers can be isolated (PubMed:16989859), some of which are not formed in the presence of a synthetic signal peptide. A single SecA monomer interacts with SecY in the channel.2 Publications

Protein-protein interaction databases

Database of interacting proteins More...DIPⁱ	DIP-59805N
IntActⁱ	P28366, 7 interactors
Molecular INTeraction database More...MINTⁱ	P28366
STRINGⁱ	224308.Bsubs1_010100019096

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	1 – 6	Combined sources	6
Beta strandⁱ	12 – 14	Combined sources	3
Helixⁱ	18 – 28	Combined sources	11
Helixⁱ	31 – 34	Combined sources	4
Helixⁱ	38 – 53	Combined sources	16
Helixⁱ	58 – 77	Combined sources	20
Helixⁱ	83 – 93	Combined sources	11
Beta strandⁱ	96 – 99	Combined sources	4
Helixⁱ	106 – 118	Combined sources	13
Turnⁱ	119 – 122	Combined sources	4
Beta strandⁱ	124 – 130	Combined sources	7
Helixⁱ	131 – 147	Combined sources	17
Beta strandⁱ	152 – 154	Combined sources	3
Beta strandⁱ	157 – 159	Combined sources	3
Helixⁱ	161 – 169	Combined sources	9
Beta strandⁱ	170 – 176	Combined sources	7
Helixⁱ	177 – 187	Combined sources	11
Helixⁱ	193 – 195	Combined sources	3
Beta strandⁱ	203 – 207	Combined sources	5
Helixⁱ	209 – 213	Combined sources	5
Turnⁱ	214 – 218	Combined sources	5
Beta strandⁱ	220 – 228	Combined sources	9
Helixⁱ	232 – 241	Combined sources	10
Turnⁱ	242 – 244	Combined sources	3
Beta strandⁱ	246 – 250	Combined sources	5
Beta strandⁱ	254 – 256	Combined sources	3
Beta strandⁱ	258 – 261	Combined sources	4
Helixⁱ	263 – 272	Combined sources	10
Turnⁱ	275 – 277	Combined sources	3
Beta strandⁱ	278 – 280	Combined sources	3
Helixⁱ	281 – 283	Combined sources	3
Helixⁱ	284 – 298	Combined sources	15
Turnⁱ	302 – 304	Combined sources	3
Beta strandⁱ	305 – 309	Combined sources	5
Beta strandⁱ	312 – 316	Combined sources	5
Turnⁱ	318 – 320	Combined sources	3
Helixⁱ	330 – 332	Combined sources	3
Helixⁱ	333 – 340	Combined sources	8
Beta strandⁱ	349 – 356	Combined sources	8
Helixⁱ	357 – 361	Combined sources	5
Beta strandⁱ	364 – 372	Combined sources	9
Helixⁱ	375 – 377	Combined sources	3
Helixⁱ	378 – 385	Combined sources	8
Beta strandⁱ	389 – 391	Combined sources	3
Beta strandⁱ	399 – 402	Combined sources	4
Beta strandⁱ	406 – 410	Combined sources	5
Helixⁱ	411 – 427	Combined sources	17
Beta strandⁱ	432 – 437	Combined sources	6
Helixⁱ	439 – 450	Combined sources	12
Turnⁱ	451 – 453	Combined sources	3
Beta strandⁱ	457 – 459	Combined sources	3
Beta strandⁱ	461 – 463	Combined sources	3
Helixⁱ	464 – 471	Combined sources	8
Turnⁱ	472 – 475	Combined sources	4
Beta strandⁱ	480 – 484	Combined sources	5
Turnⁱ	485 – 490	Combined sources	6
Turnⁱ	497 – 499	Combined sources	3
Helixⁱ	500 – 502	Combined sources	3
Beta strandⁱ	504 – 511	Combined sources	8
Helixⁱ	516 – 523	Combined sources	8
Helixⁱ	528 – 530	Combined sources	3
Beta strandⁱ	533 – 540	Combined sources	8
Helixⁱ	545 – 547	Combined sources	3
Helixⁱ	550 – 561	Combined sources	12
Beta strandⁱ	565 – 567	Combined sources	3
Helixⁱ	572 – 618	Combined sources	47
Beta strandⁱ	621 – 623	Combined sources	3
Helixⁱ	624 – 641	Combined sources	18
Beta strandⁱ	645 – 648	Combined sources	4
Helixⁱ	649 – 651	Combined sources	3
Helixⁱ	657 – 662	Combined sources	6
Turnⁱ	663 – 665	Combined sources	3
Beta strandⁱ	668 – 671	Combined sources	4
Beta strandⁱ	672 – 675	Combined sources	4
Helixⁱ	681 – 702	Combined sources	22
Turnⁱ	704 – 706	Combined sources	3
Helixⁱ	707 – 736	Combined sources	30
Helixⁱ	738 – 740	Combined sources	3
Beta strandⁱ	744 – 746	Combined sources	3
Helixⁱ	748 – 776	Combined sources	29
Beta strandⁱ	794 – 797	Combined sources	4

Show more details

3D structure databases

ProteinModelPortalⁱ	P28366
SMRⁱ	P28366
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	P28366

EvolutionaryTraceⁱ

P28366

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the SecA family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	COG0653 LUCA
HOGENOMⁱ	HOG000218169
InParanoidⁱ	P28366
KEGG Orthology (KO) More...KOⁱ	K03070
OMAⁱ	FEYDEVM
PhylomeDBⁱ	P28366

Family and domain databases

HAMAPⁱ	MF_01382 SecA, 1 hit
InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR004027 SEC_C_motif IPR000185 SecA IPR020937 SecA_CS IPR011115 SecA_DEAD IPR014018 SecA_motor_DEAD IPR011130 SecA_preprotein_X-link_dom IPR011116 SecA_Wing/Scaffold IPR036266 SecA_Wing/Scaffold_sf IPR036670 SecA_X-link_sf
PANTHERⁱ	PTHR30612 PTHR30612, 2 hits
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF02810 SEC-C, 1 hit PF07517 SecA_DEAD, 1 hit PF01043 SecA_PP_bind, 1 hit PF07516 SecA_SW, 1 hit
PRINTSⁱ	PR00906 SECA
SMARTⁱ	View protein in SMART SM00957 SecA_DEAD, 1 hit SM00958 SecA_PP_bind, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 3 hits SSF81767 SSF81767, 1 hit SSF81886 SSF81886, 2 hits
TIGRFAMsⁱ	TIGR00963 secA, 1 hit
PROSITEⁱ	View protein in PROSITE PS01312 SECA, 1 hit PS51196 SECA_MOTOR_DEAD, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

P28366-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MLGILNKMFD PTKRTLNRYE KIANDIDAIR GDYENLSDDA LKHKTIEFKE 
        60         70         80         90        100
RLEKGATTDD LLVEAFAVVR EASRRVTGMF PFKVQLMGGV ALHDGNIAEM 
       110        120        130        140        150
KTGEGKTLTS TLPVYLNALT GKGVHVVTVN EYLASRDAEQ MGKIFEFLGL 
       160        170        180        190        200
TVGLNLNSMS KDEKREAYAA DITYSTNNEL GFDYLRDNMV LYKEQMVQRP 
       210        220        230        240        250
LHFAVIDEVD SILIDEARTP LIISGQAAKS TKLYVQANAF VRTLKAEKDY 
       260        270        280        290        300
TYDIKTKAVQ LTEEGMTKAE KAFGIDNLFD VKHVALNHHI NQALKAHVAM 
       310        320        330        340        350
QKDVDYVVED GQVVIVDSFT GRLMKGRRYS EGLHQAIEAK EGLEIQNESM 
       360        370        380        390        400
TLATITFQNY FRMYEKLAGM TGTAKTEEEE FRNIYNMQVV TIPTNRPVVR 
       410        420        430        440        450
DDRPDLIYRT MEGKFKAVAE DVAQRYMTGQ PVLVGTVAVE TSELISKLLK 
       460        470        480        490        500
NKGIPHQVLN AKNHEREAQI IEEAGQKGAV TIATNMAGRG TDIKLGEGVK 
       510        520        530        540        550
ELGGLAVVGT ERHESRRIDN QLRGRSGRQG DPGITQFYLS MEDELMRRFG 
       560        570        580        590        600
AERTMAMLDR FGMDDSTPIQ SKMVSRAVES SQKRVEGNNF DSRKQLLQYD 
       610        620        630        640        650
DVLRQQREVI YKQRFEVIDS ENLREIVENM IKSSLERAIA AYTPREELPE 
       660        670        680        690        700
EWKLDGLVDL INTTYLDEGA LEKSDIFGKE PDEMLELIMD RIITKYNEKE 
       710        720        730        740        750
EQFGKEQMRE FEKVIVLRAV DSKWMDHIDA MDQLRQGIHL RAYAQTNPLR 
       760        770        780        790        800
EYQMEGFAMF EHMIESIEDE VAKFVMKAEI ENNLEREEVV QGQTTAHQPQ 
       810        820        830        840 
EGDDNKKAKK APVRKVVDIG RNAPCHCGSG KKYKNCCGRT E

Length:841

Mass (Da):95,531

Last modified:December 1, 1992 - v1

Checksum:ⁱ9AAC3630139F5EFF

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	126	V → I in CAA43977 (PubMed:1832735).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D10279 Genomic DNA Translation: BAA01122.1 U56901 Genomic DNA Translation: AAC44957.1 AL009126 Genomic DNA Translation: CAB15547.1 X62035 Genomic DNA Translation: CAA43977.1
PIRⁱ	JQ0647
NCBI Reference Sequences More...RefSeqⁱ	NP_391410.1, NC_000964.3 WP_003228033.1, NZ_JNCM01000033.1

Genome annotation databases

EnsemblBacteriaⁱ	CAB15547; CAB15547; BSU35300
GeneIDⁱ	936711
KEGGⁱ	bsu:BSU35300
PATRICⁱ	fig\|224308.179.peg.3820

Protein	Similar proteins		Species	Score	Length	Source
P28366	Protein translocase subunit SecA		Bacillus sp. DM2		841	UniRef100_P28366
Protein translocase subunit SecA		BACIU		841
Protein translocase subunit SecA		Bacillus sp. EGD-AK10		841
Protein translocase subunit SecA		Bacillus subtilis subsp. subtilis str. SC-8		841
Protein translocase subunit SecA		Bacillus subtilis BEST7613		841
+8

Protein	Similar proteins		Species	Score	Length	Source
P28366	Protein translocase subunit SecA		BACLD		841	UniRef90_P28366
Protein translocase subunit SecA		BACVZ		841
Protein translocase subunit SecA		Bacillus sp. DM2		841
Protein translocase subunit SecA		BACIU		841
Protein translocase subunit SecA		Bacillus sp. EGD-AK10		841
+147

Protein	Similar proteins		Species	Score	Length	Source
P28366	Protein translocase subunit SecA		BACVZ		841	UniRef50_P28366
Protein translocase subunit SecA		BACLD		841
Protein translocase subunit SecA 1		BACAN		835
Protein translocase subunit SecA		BACC2		835
Protein translocase subunit SecA		BACC4		835
+2533

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	D10279 Genomic DNA Translation: BAA01122.1 U56901 Genomic DNA Translation: AAC44957.1 AL009126 Genomic DNA Translation: CAB15547.1 X62035 Genomic DNA Translation: CAA43977.1
PIRⁱ	JQ0647
RefSeqⁱ	NP_391410.1, NC_000964.3 WP_003228033.1, NZ_JNCM01000033.1

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1M6N	X-ray	2.70	A	1-802	[»]
	1M74	X-ray	3.00	A	1-802	[»]
	1TF2	X-ray	2.90	A	1-841	[»]
	1TF5	X-ray	2.18	A	1-841	[»]
	2IBM	X-ray	3.20	A/B	1-780	[»]
	3DL8	X-ray	7.50	A/B	1-779	[»]
	3IQM	X-ray	3.40	A	1-802	[»]
	3IQY	X-ray	3.30	A	1-841	[»]
	3JV2	X-ray	2.50	A/B	1-780	[»]
	5EUL	X-ray	3.70	A	1-780	[»]
ProteinModelPortalⁱ	P28366
SMRⁱ	P28366
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

DIPⁱ	DIP-59805N
IntActⁱ	P28366, 7 interactors
MINTⁱ	P28366
STRINGⁱ	224308.Bsubs1_010100019096

Proteomic databases

PaxDbⁱ	P28366
PRIDEⁱ	P28366

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	CAB15547; CAB15547; BSU35300
GeneIDⁱ	936711
KEGGⁱ	bsu:BSU35300
PATRICⁱ	fig\|224308.179.peg.3820

Phylogenomic databases

eggNOGⁱ	COG0653 LUCA
HOGENOMⁱ	HOG000218169
InParanoidⁱ	P28366
KOⁱ	K03070
OMAⁱ	FEYDEVM
PhylomeDBⁱ	P28366

Enzyme and pathway databases

BioCycⁱ	BSUB:BSU35300-MONOMER
BRENDAⁱ	3.6.3.B1 658

Miscellaneous databases

EvolutionaryTraceⁱ	P28366

EvolutionaryTraceⁱ

P28366

Family and domain databases

HAMAPⁱ	MF_01382 SecA, 1 hit
InterProⁱ	View protein in InterPro IPR027417 P-loop_NTPase IPR004027 SEC_C_motif IPR000185 SecA IPR020937 SecA_CS IPR011115 SecA_DEAD IPR014018 SecA_motor_DEAD IPR011130 SecA_preprotein_X-link_dom IPR011116 SecA_Wing/Scaffold IPR036266 SecA_Wing/Scaffold_sf IPR036670 SecA_X-link_sf
PANTHERⁱ	PTHR30612 PTHR30612, 2 hits
Pfamⁱ	View protein in Pfam PF02810 SEC-C, 1 hit PF07517 SecA_DEAD, 1 hit PF01043 SecA_PP_bind, 1 hit PF07516 SecA_SW, 1 hit
PRINTSⁱ	PR00906 SECA
SMARTⁱ	View protein in SMART SM00957 SecA_DEAD, 1 hit SM00958 SecA_PP_bind, 1 hit
SUPFAMⁱ	SSF52540 SSF52540, 3 hits SSF81767 SSF81767, 1 hit SSF81886 SSF81886, 2 hits
TIGRFAMsⁱ	TIGR00963 secA, 1 hit
PROSITEⁱ	View protein in PROSITE PS01312 SECA, 1 hit PS51196 SECA_MOTOR_DEAD, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SECA_BACSU
Accessionⁱ	P28366Primary (citable) accession number: P28366
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 1, 1992
	Last sequence update:	December 1, 1992
	Last modified:	October 10, 2018
	This is version 160 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Prokaryotic Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Bacillus subtilis
Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

UniProtKB

UniParc

Help

UniRef

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Annotation systems

Supporting data

UniProtKB - P28366 (SECA_BACSU)

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Protein translocase subunit SecA

secA

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ