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Protein

Tropomodulin-1

Gene

TMOD1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • actin binding Source: UniProtKB
  • actin filament binding Source: InterPro
  • tropomyosin binding Source: GO_Central

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-390522 Striated Muscle Contraction

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tropomodulin-1
Alternative name(s):
Erythrocyte tropomodulin
Short name:
E-Tmod
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TMOD1
Synonyms:D9S57E, TMOD
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000136842.13

Human Gene Nomenclature Database

More...
HGNCi
HGNC:11871 TMOD1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
190930 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P28289

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
7111

Open Targets

More...
OpenTargetsi
ENSG00000136842

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA36572

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TMOD1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
135922

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001861281 – 359Tropomodulin-1Add BLAST359

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P28289

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P28289

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P28289

PeptideAtlas

More...
PeptideAtlasi
P28289

PRoteomics IDEntifications database

More...
PRIDEi
P28289

ProteomicsDB human proteome resource

More...
ProteomicsDBi
54457

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P28289

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P28289

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in the erythrocyte, heart and skeletal muscle.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000136842 Expressed in 203 organ(s), highest expression level in type B pancreatic cell

CleanEx database of gene expression profiles

More...
CleanExi
HS_TMOD1

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P28289 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA051202

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to the N-terminus of isoforms 2/3 of TPM3 and to actin.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
112966, 53 interactors

Protein interaction database and analysis system

More...
IntActi
P28289, 48 interactors

Molecular INTeraction database

More...
MINTi
P28289

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000259365

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1359
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P28289

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P28289

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni39 – 138Tropomyosin-bindingSequence analysisAdd BLAST100

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the tropomodulin family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3735 Eukaryota
ENOG410YAHM LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158695

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000261624

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG056172

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P28289

KEGG Orthology (KO)

More...
KOi
K10370

Identification of Orthologs from Complete Genome Data

More...
OMAi
RGKIWVP

Database of Orthologous Groups

More...
OrthoDBi
EOG091G0C3H

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P28289

TreeFam database of animal gene trees

More...
TreeFami
TF315841

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR032675 LRR_dom_sf
IPR004934 TMOD
IPR030135 TMOD1

The PANTHER Classification System

More...
PANTHERi
PTHR10901 PTHR10901, 1 hit
PTHR10901:SF8 PTHR10901:SF8, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03250 Tropomodulin, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: P28289-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSYRRELEKY RDLDEDEILG ALTEEELRTL ENELDELDPD NALLPAGLRQ
60 70 80 90 100
KDQTTKAPTG PFKREELLDH LEKQAKEFKD REDLVPYTGE KRGKVWVPKQ
110 120 130 140 150
KPLDPVLESV TLEPELEEAL ANASDAELCD IAAILGMHTL MSNQQYYQAL
160 170 180 190 200
SSSSIMNKEG LNSVIKPTQY KPVPDEEPNS TDVEETLERI KNNDPKLEEV
210 220 230 240 250
NLNNIRNIPI PTLKAYAEAL KENSYVKKFS IVGTRSNDPV AYALAEMLKE
260 270 280 290 300
NKVLKTLNVE SNFISGAGIL RLVEALPYNT SLVEMKIDNQ SQPLGNKVEM
310 320 330 340 350
EIVSMLEKNA TLLKFGYHFT QQGPRLRASN AMMNNNDLVR KRRLADLTGP

IIPKCRSGV
Length:359
Mass (Da):40,569
Last modified:December 1, 1992 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i732B7D7798B88A48
GO
Isoform 2 (identifier: P28289-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-6: MSYRRE → MSQVLS
     7-133: Missing.

Note: No experimental confirmation available.
Show »
Length:232
Mass (Da):26,014
Checksum:i80DEC95EB154DF1F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti17E → K in AAH02660 (PubMed:15489334).Curated1
Sequence conflicti76K → E in BAG37124 (PubMed:14702039).Curated1
Sequence conflicti289N → S in BAG37124 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0568631 – 6MSYRRE → MSQVLS in isoform 2. 1 Publication6
Alternative sequenceiVSP_0568647 – 133Missing in isoform 2. 1 PublicationAdd BLAST127

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M77016 mRNA Translation: AAA61224.1
AF288155
, AF288147, AF288148, AF288149, AF288150, AF288151, AF288152, AF288153, AF288154 Genomic DNA Translation: AAG30124.1
AK095748 mRNA Translation: BAG53119.1
AK314533 mRNA Translation: BAG37124.1
AL162385 Genomic DNA No translation available.
BC002660 mRNA Translation: AAH02660.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS6726.1 [P28289-1]

Protein sequence database of the Protein Information Resource

More...
PIRi
A42336

NCBI Reference Sequences

More...
RefSeqi
NP_001159588.1, NM_001166116.1 [P28289-1]
NP_003266.1, NM_003275.3 [P28289-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.404289
Hs.723236

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000259365; ENSP00000259365; ENSG00000136842 [P28289-1]
ENST00000375175; ENSP00000364318; ENSG00000136842 [P28289-2]
ENST00000395211; ENSP00000378637; ENSG00000136842 [P28289-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
7111

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:7111

UCSC genome browser

More...
UCSCi
uc004axk.3 human [P28289-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M77016 mRNA Translation: AAA61224.1
AF288155
, AF288147, AF288148, AF288149, AF288150, AF288151, AF288152, AF288153, AF288154 Genomic DNA Translation: AAG30124.1
AK095748 mRNA Translation: BAG53119.1
AK314533 mRNA Translation: BAG37124.1
AL162385 Genomic DNA No translation available.
BC002660 mRNA Translation: AAH02660.1
CCDSiCCDS6726.1 [P28289-1]
PIRiA42336
RefSeqiNP_001159588.1, NM_001166116.1 [P28289-1]
NP_003266.1, NM_003275.3 [P28289-1]
UniGeneiHs.404289
Hs.723236

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4PKGX-ray1.80G50-101[»]
4PKHX-ray2.15B/E/G/J50-101[»]
4PKIX-ray2.30G160-349[»]
4Z8GX-ray2.10A163-228[»]
4Z94X-ray2.40G160-228[»]
ProteinModelPortaliP28289
SMRiP28289
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi112966, 53 interactors
IntActiP28289, 48 interactors
MINTiP28289
STRINGi9606.ENSP00000259365

PTM databases

iPTMnetiP28289
PhosphoSitePlusiP28289

Polymorphism and mutation databases

BioMutaiTMOD1
DMDMi135922

Proteomic databases

EPDiP28289
MaxQBiP28289
PaxDbiP28289
PeptideAtlasiP28289
PRIDEiP28289
ProteomicsDBi54457

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
7111
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000259365; ENSP00000259365; ENSG00000136842 [P28289-1]
ENST00000375175; ENSP00000364318; ENSG00000136842 [P28289-2]
ENST00000395211; ENSP00000378637; ENSG00000136842 [P28289-1]
GeneIDi7111
KEGGihsa:7111
UCSCiuc004axk.3 human [P28289-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7111
DisGeNETi7111
EuPathDBiHostDB:ENSG00000136842.13

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TMOD1
HGNCiHGNC:11871 TMOD1
HPAiHPA051202
MIMi190930 gene
neXtProtiNX_P28289
OpenTargetsiENSG00000136842
PharmGKBiPA36572

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG3735 Eukaryota
ENOG410YAHM LUCA
GeneTreeiENSGT00940000158695
HOGENOMiHOG000261624
HOVERGENiHBG056172
InParanoidiP28289
KOiK10370
OMAiRGKIWVP
OrthoDBiEOG091G0C3H
PhylomeDBiP28289
TreeFamiTF315841

Enzyme and pathway databases

ReactomeiR-HSA-390522 Striated Muscle Contraction

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TMOD1 human

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
TMOD1

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
7111

Protein Ontology

More...
PROi
PR:P28289

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000136842 Expressed in 203 organ(s), highest expression level in type B pancreatic cell
CleanExiHS_TMOD1
GenevisibleiP28289 HS

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR032675 LRR_dom_sf
IPR004934 TMOD
IPR030135 TMOD1
PANTHERiPTHR10901 PTHR10901, 1 hit
PTHR10901:SF8 PTHR10901:SF8, 1 hit
PfamiView protein in Pfam
PF03250 Tropomodulin, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTMOD1_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P28289
Secondary accession number(s): B2RB77, Q5T7W3, Q9BUF1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: December 5, 2018
This is version 160 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 9
    Human chromosome 9: entries, gene names and cross-references to MIM
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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