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Protein

Tyrosine-protein phosphatase 4

Gene

STY-4

Organism
Styela plicata (Wrinkled sea squirt) (Ascidia plicata)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei78SubstrateSequence analysis1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine-protein phosphatase 4 (EC:3.1.3.48)
Gene namesi
Name:STY-4
OrganismiStyela plicata (Wrinkled sea squirt) (Ascidia plicata)
Taxonomic identifieri7726 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaStyelidaeStyela

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_0000094892‹1 – ›109Tyrosine-protein phosphatase 4Add BLAST›109

Structurei

3D structure databases

ProteinModelPortaliP28196
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini‹1 – ›109Tyrosine-protein phosphatasePROSITE-ProRule annotationAdd BLAST›109

Sequence similaritiesi

Family and domain databases

Gene3Di3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR027262 Tyr_Pase_rcpt_alpha
PANTHERiPTHR19134:SF433 PTHR19134:SF433, 1 hit
PfamiView protein in Pfam
PF00102 Y_phosphatase, 1 hit
SUPFAMiSSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS50055 TYR_PHOSPHATASE_PTP, 1 hit

Sequencei

Sequence statusi: Fragment.

P28196-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
SKSASIVMLT ELVERGQAKC AQYWPNDGIL TFGDIEVEFL SVNESEDYSE
60 70 80 90 100
RDFKVSNRSD NNGSQLIVKQ FHYHGWPEVG APVSGYSMIE LVEDVQKQQQ

NSGNHPIVI
Length:109
Mass (Da):12,262
Last modified:December 1, 1992 - v1
Checksum:i5D5681534B7C8090
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei11
Non-terminal residuei1091

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37989 mRNA Translation: AAA29822.1

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37989 mRNA Translation: AAA29822.1

3D structure databases

ProteinModelPortaliP28196
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR027262 Tyr_Pase_rcpt_alpha
PANTHERiPTHR19134:SF433 PTHR19134:SF433, 1 hit
PfamiView protein in Pfam
PF00102 Y_phosphatase, 1 hit
SUPFAMiSSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS50055 TYR_PHOSPHATASE_PTP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPTP4_STYPL
AccessioniPrimary (citable) accession number: P28196
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 1992
Last sequence update: December 1, 1992
Last modified: June 20, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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