UniProtKB - P27844 (RARD_ECOLI)
Protein
Protein RarD
Gene
rarD
Organism
Escherichia coli (strain K12)
Status
Functioni
Keywordsi
Biological process | Transport |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11466-MONOMER |
Protein family/group databases
TCDBi | 2.A.7.7.2, the drug/metabolite transporter (dmt) superfamily |
Names & Taxonomyi
Protein namesi | Recommended name: Protein RarD |
Gene namesi | Name:rarD Ordered Locus Names:b3819, JW5589 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
Plasma Membrane
- integral component of plasma membrane Source: InterPro
- plasma membrane Source: EcoCyc
Other locations
- integral component of membrane Source: EcoCyc
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 11 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 12 – 34 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 35 – 37 | PeriplasmicSequence analysis | 3 | |
Transmembranei | 38 – 60 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 61 – 72 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 73 – 95 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 96 – 99 | PeriplasmicSequence analysis | 4 | |
Transmembranei | 100 – 122 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 123 – 128 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 129 – 146 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 147 – 149 | PeriplasmicSequence analysis | 3 | |
Transmembranei | 150 – 167 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 168 – 179 | CytoplasmicSequence analysisAdd BLAST | 12 | |
Transmembranei | 180 – 197 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 198 – 211 | PeriplasmicSequence analysisAdd BLAST | 14 | |
Transmembranei | 212 – 234 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 235 – 238 | CytoplasmicSequence analysis | 4 | |
Transmembranei | 239 – 261 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 262 – 270 | PeriplasmicSequence analysis | 9 | |
Transmembranei | 271 – 290 | HelicalSequence analysisAdd BLAST | 20 | |
Topological domaini | 291 – 296 | CytoplasmicSequence analysis | 6 |
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000108152 | 1 – 296 | Protein RarDAdd BLAST | 296 |
Proteomic databases
PaxDbi | P27844 |
PRIDEi | P27844 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4261790, 13 interactors |
IntActi | P27844, 1 interactor |
STRINGi | 511145.b3819 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 18 – 145 | EamAAdd BLAST | 128 |
Sequence similaritiesi
Belongs to the EamA transporter family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2962, Bacteria |
HOGENOMi | CLU_054508_1_0_6 |
InParanoidi | P27844 |
PhylomeDBi | P27844 |
Family and domain databases
InterProi | View protein in InterPro IPR000620, EamA_dom IPR004626, RarD |
PANTHERi | PTHR22911:SF114, PTHR22911:SF114, 1 hit |
Pfami | View protein in Pfam PF00892, EamA, 2 hits |
TIGRFAMsi | TIGR00688, rarD, 1 hit |
i Sequence
Sequence statusi: Complete.
P27844-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDAKQTRQGV LLALAAYFIW GIAPAYFKLI YYVPADEILT HRVIWSFFFM
60 70 80 90 100
VVLMSICRQW SYLKTLIQTP QKIFMLAVSA VLIGGNWLLF IWAVNNHHML
110 120 130 140 150
EASLGYFINP LVNIVLGMIF LGERFRRMQW LAVILAICGV LVQLWTFGSL
160 170 180 190 200
PIIALGLAFS FAFYGLVRKK IAVEAQTGML IETMWLLPVA AIYLFAIADS
210 220 230 240 250
STSHMGQNPM SLNLLLIAAG IVTTVPLLCF TAAATRLRLS TLGFFQYIGP
260 270 280 290
TLMFLLAVTF YGEKPGADKM VTFAFIWVAL AIFVMDAIYT QRRTSK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 102 | A → R in AAA67615 (PubMed:1379743).Curated | 1 | |
Sequence conflicti | 123 – 124 | ER → DG in AAA67615 (PubMed:1379743).Curated | 2 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L02122 Genomic DNA Translation: AAD15041.1 M87049 Genomic DNA Translation: AAA67615.1 U00096 Genomic DNA Translation: AAT48220.1 AP009048 Genomic DNA Translation: BAE77482.1 |
PIRi | S30709 S30746 |
RefSeqi | WP_000339104.1, NZ_STEB01000021.1 YP_026262.1, NC_000913.3 |
Genome annotation databases
EnsemblBacteriai | AAT48220; AAT48220; b3819 BAE77482; BAE77482; BAE77482 |
GeneIDi | 57730191 948330 |
KEGGi | ecj:JW5589 eco:b3819 |
PATRICi | fig|1411691.4.peg.2888 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L02122 Genomic DNA Translation: AAD15041.1 M87049 Genomic DNA Translation: AAA67615.1 U00096 Genomic DNA Translation: AAT48220.1 AP009048 Genomic DNA Translation: BAE77482.1 |
PIRi | S30709 S30746 |
RefSeqi | WP_000339104.1, NZ_STEB01000021.1 YP_026262.1, NC_000913.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4261790, 13 interactors |
IntActi | P27844, 1 interactor |
STRINGi | 511145.b3819 |
Protein family/group databases
TCDBi | 2.A.7.7.2, the drug/metabolite transporter (dmt) superfamily |
Proteomic databases
PaxDbi | P27844 |
PRIDEi | P27844 |
Genome annotation databases
EnsemblBacteriai | AAT48220; AAT48220; b3819 BAE77482; BAE77482; BAE77482 |
GeneIDi | 57730191 948330 |
KEGGi | ecj:JW5589 eco:b3819 |
PATRICi | fig|1411691.4.peg.2888 |
Organism-specific databases
EchoBASEi | EB1434 |
Phylogenomic databases
eggNOGi | COG2962, Bacteria |
HOGENOMi | CLU_054508_1_0_6 |
InParanoidi | P27844 |
PhylomeDBi | P27844 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11466-MONOMER |
Miscellaneous databases
PROi | PR:P27844 |
Family and domain databases
InterProi | View protein in InterPro IPR000620, EamA_dom IPR004626, RarD |
PANTHERi | PTHR22911:SF114, PTHR22911:SF114, 1 hit |
Pfami | View protein in Pfam PF00892, EamA, 2 hits |
TIGRFAMsi | TIGR00688, rarD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | RARD_ECOLI | |
Accessioni | P27844Primary (citable) accession number: P27844 Secondary accession number(s): Q2M8C4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 1, 1992 |
Last sequence update: | April 1, 1993 | |
Last modified: | February 10, 2021 | |
This is version 144 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families