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Entry version 199 (17 Jun 2020)
Sequence version 1 (01 Aug 1992)
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Protein

Transcription elongation factor SPT5

Gene

SPT5

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.5 Publications

Miscellaneous

It is phosphorylated in a PKA-dependent manner in vitro.
Present with 2340 molecules/cell in log phase SD medium.1 Publication

Caution

Was originally thought to be involved in the transcription initiation step.Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA processing, Transcription

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
YEAST:G3O-32614-MONOMER

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SCE-113418 Formation of the Early Elongation Complex
R-SCE-674695 RNA Polymerase II Pre-transcription Events
R-SCE-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-SCE-72086 mRNA Capping
R-SCE-75955 RNA Polymerase II Transcription Elongation
R-SCE-77075 RNA Pol II CTD phosphorylation and interaction with CE

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Transcription elongation factor SPT5
Alternative name(s):
Chromatin elongation factor SPT5
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SPT5
Ordered Locus Names:YML010W
ORF Names:YM9571.08
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome XIII

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
FungiDB:YML010W

Saccharomyces Genome Database

More...
SGDi
S000004470 SPT5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002084771 – 1063Transcription elongation factor SPT5Add BLAST1063

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei35PhosphothreonineCombined sources1
Modified residuei133PhosphothreonineCombined sources1
Modified residuei136PhosphoserineCombined sources1
Modified residuei188PhosphoserineCombined sources1
Modified residuei219PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P27692

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P27692

PRoteomics IDEntifications database

More...
PRIDEi
P27692

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P27692

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the SPT4-SPT5 complex.

Interacts with RNA polymerase II.

Interacts with SHE2.

2 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
35159, 198 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1661 SPT4-SPT5 transcription elongation factor complex

Database of interacting proteins

More...
DIPi
DIP-6621N

Protein interaction database and analysis system

More...
IntActi
P27692, 94 interactors

Molecular INTeraction database

More...
MINTi
P27692

STRING: functional protein association networks

More...
STRINGi
4932.YML010W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P27692 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11063
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P27692

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P27692

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini382 – 415KOW 1Add BLAST34
Domaini533 – 560KOW 2Add BLAST28
Domaini584 – 615KOW 3Add BLAST32
Domaini799 – 832KOW 4Add BLAST34
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati931 – 93616
Repeati937 – 94226
Repeati948 – 95336
Repeati958 – 96346
Repeati969 – 97456
Repeati975 – 98066
Repeati981 – 98676
Repeati987 – 99286
Repeati1000 – 100596
Repeati1009 – 1014106
Repeati1015 – 1020116
Repeati1032 – 1037126
Repeati1043 – 1048136
Repeati1052 – 1057146
Repeati1058 – 1063156

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni931 – 106315 X 6 AA tandem repeats of S-[TA]-W-G-G-[AQ]Add BLAST133

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi148 – 167Asp/Glu-rich (acidic)Add BLAST20
Compositional biasi189 – 199Asp/Glu-rich (acidic)Add BLAST11

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The carboxy-terminal repeats are critical for activity.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SPT5 family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00440000037640

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_003537_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P27692

KEGG Orthology (KO)

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KOi
K15172

Identification of Orthologs from Complete Genome Data

More...
OMAi
GYMNTPS

Family and domain databases

Conserved Domains Database

More...
CDDi
cd06081 KOW_Spt5_1, 1 hit
cd06082 KOW_Spt5_2, 1 hit
cd06083 KOW_Spt5_3, 1 hit
cd06084 KOW_Spt5_4, 1 hit
cd06085 KOW_Spt5_5, 1 hit
cd09888 NGN_Euk, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.30.30, 3 hits
3.30.70.940, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005824 KOW
IPR041973 KOW_Spt5_1
IPR041975 KOW_Spt5_2
IPR041976 KOW_Spt5_3
IPR041977 KOW_Spt5_4
IPR041978 KOW_Spt5_5
IPR005100 NGN-domain
IPR006645 NGN_dom
IPR036735 NGN_dom_sf
IPR039385 NGN_Euk
IPR014722 Rib_L2_dom2
IPR039659 SPT5
IPR024945 Spt5_C_dom
IPR022581 Spt5_N
IPR017071 TF_Spt5_eukaryote
IPR008991 Translation_prot_SH3-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11125 PTHR11125, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03439 Spt5-NGN, 1 hit
PF11942 Spt5_N, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036945 Spt5, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01104 CTD, 1 hit
SM00739 KOW, 4 hits
SM00738 NGN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50104 SSF50104, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P27692-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDNSDTNVS MQDHDQQFAD PVVVPQSTDT KDENTSDKDT VDSGNVTTTE
60 70 80 90 100
STERAESTSN IPPLDGEEKE AKSEPQQPED NAETAATEQV SSSNGPATDD
110 120 130 140 150
AQATLNTDSS EANEIVKKEE GSDERKRPRE EDTKNSDGDT KDEGDNKDED
160 170 180 190 200
DDEDDDDDDD DEDDDDEAPT KRRRQERNRF LDIEAEVSDD EDEDEDEEDS
210 220 230 240 250
ELVREGFITH GDDEDDEASA PGARRDDRLH RQLDQDLNKT SEEDAQRLAK
260 270 280 290 300
ELRERYGRSS SKQYRAAAQD GYVPQRFLLP SVDTATIWGV RCRPGKEKEL
310 320 330 340 350
IRKLLKKKFN LDRAMGKKKL KILSIFQRDN YTGRIYIEAP KQSVIEKFCN
360 370 380 390 400
GVPDIYISQK LLIPVQELPL LLKPNKSDDV ALEEGSYVRI KRGIYKGDLA
410 420 430 440 450
MVDQISENNL EVMLKIVPRL DYGKFDEIDP TTQQRKSRRP TFAHRAPPQL
460 470 480 490 500
FNPTMALRLD QANLYKRDDR HFTYKNEDYI DGYLYKSFRI QHVETKNIQP
510 520 530 540 550
TVEELARFGS KEGAVDLTSV SQSIKKAQAA KVTFQPGDRI EVLNGEQRGS
560 570 580 590 600
KGIVTRTTKD IATIKLNGFT TPLEFPISTL RKIFEPGDHV TVINGEHQGD
610 620 630 640 650
AGLVLMVEQG QVTFMSTQTS REVTITANNL SKSIDTTATS SEYALHDIVE
660 670 680 690 700
LSAKNVACII QAGHDIFKVI DETGKVSTIT KGSILSKINT ARARVSSVDA
710 720 730 740 750
NGNEIKIGDT IVEKVGSRRE GQVLYIQTQQ IFVVSKKIVE NAGVFVVNPS
760 770 780 790 800
NVEAVASKDN MLSNKMDLSK MNPEIISKMG PPSSKTFQQP IQSRGGREVA
810 820 830 840 850
LGKTVRIRSA GYKGQLGIVK DVNGDKATVE LHSKNKHITI DKHKLTYYNR
860 870 880 890 900
EGGEGITYDE LVNRRGRVPQ ARMGPSYVSA PRNMATGGIA AGAAATSSGL
910 920 930 940 950
SGGMTPGWSS FDGGKTPAVN AHGGSGGGGV SSWGGASTWG GQGNGGASAW
960 970 980 990 1000
GGAGGGASAW GGQGTGATST WGGASAWGNK SSWGGASTWA SGGESNGAMS
1010 1020 1030 1040 1050
TWGGTGDRSA YGGASTWGGN NNNKSTRDGG ASAWGNQDDG NRSAWNNQGN
1060
KSNYGGNSTW GGH
Length:1,063
Mass (Da):115,650
Last modified:August 1, 1992 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE4324DB6B1E4721A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M62882 Genomic DNA Translation: AAA35085.1
Z49810 Genomic DNA Translation: CAA89942.1
BK006946 Genomic DNA Translation: DAA09888.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A40253

NCBI Reference Sequences

More...
RefSeqi
NP_013703.1, NM_001182366.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YML010W_mRNA; YML010W; YML010W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
854999

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YML010W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M62882 Genomic DNA Translation: AAA35085.1
Z49810 Genomic DNA Translation: CAA89942.1
BK006946 Genomic DNA Translation: DAA09888.1
PIRiA40253
RefSeqiNP_013703.1, NM_001182366.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2EXUX-ray2.23A285-375[»]
4YTKX-ray1.09A382-511[»]
4YTLX-ray1.60A/B534-632[»]
SMRiP27692
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi35159, 198 interactors
ComplexPortaliCPX-1661 SPT4-SPT5 transcription elongation factor complex
DIPiDIP-6621N
IntActiP27692, 94 interactors
MINTiP27692
STRINGi4932.YML010W

PTM databases

iPTMnetiP27692

Proteomic databases

MaxQBiP27692
PaxDbiP27692
PRIDEiP27692

Genome annotation databases

EnsemblFungiiYML010W_mRNA; YML010W; YML010W
GeneIDi854999
KEGGisce:YML010W

Organism-specific databases

EuPathDBiFungiDB:YML010W
SGDiS000004470 SPT5

Phylogenomic databases

GeneTreeiENSGT00440000037640
HOGENOMiCLU_003537_1_0_1
InParanoidiP27692
KOiK15172
OMAiGYMNTPS

Enzyme and pathway databases

BioCyciYEAST:G3O-32614-MONOMER
ReactomeiR-SCE-113418 Formation of the Early Elongation Complex
R-SCE-674695 RNA Polymerase II Pre-transcription Events
R-SCE-6796648 TP53 Regulates Transcription of DNA Repair Genes
R-SCE-72086 mRNA Capping
R-SCE-75955 RNA Polymerase II Transcription Elongation
R-SCE-77075 RNA Pol II CTD phosphorylation and interaction with CE

Miscellaneous databases

EvolutionaryTraceiP27692

Protein Ontology

More...
PROi
PR:P27692
RNActiP27692 protein

Family and domain databases

CDDicd06081 KOW_Spt5_1, 1 hit
cd06082 KOW_Spt5_2, 1 hit
cd06083 KOW_Spt5_3, 1 hit
cd06084 KOW_Spt5_4, 1 hit
cd06085 KOW_Spt5_5, 1 hit
cd09888 NGN_Euk, 1 hit
Gene3Di2.30.30.30, 3 hits
3.30.70.940, 1 hit
InterProiView protein in InterPro
IPR005824 KOW
IPR041973 KOW_Spt5_1
IPR041975 KOW_Spt5_2
IPR041976 KOW_Spt5_3
IPR041977 KOW_Spt5_4
IPR041978 KOW_Spt5_5
IPR005100 NGN-domain
IPR006645 NGN_dom
IPR036735 NGN_dom_sf
IPR039385 NGN_Euk
IPR014722 Rib_L2_dom2
IPR039659 SPT5
IPR024945 Spt5_C_dom
IPR022581 Spt5_N
IPR017071 TF_Spt5_eukaryote
IPR008991 Translation_prot_SH3-like_sf
PANTHERiPTHR11125 PTHR11125, 1 hit
PfamiView protein in Pfam
PF03439 Spt5-NGN, 1 hit
PF11942 Spt5_N, 1 hit
PIRSFiPIRSF036945 Spt5, 1 hit
SMARTiView protein in SMART
SM01104 CTD, 1 hit
SM00739 KOW, 4 hits
SM00738 NGN, 1 hit
SUPFAMiSSF50104 SSF50104, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSPT5_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P27692
Secondary accession number(s): D6VZG4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: August 1, 1992
Last modified: June 17, 2020
This is version 199 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names
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