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UniProtKB - P27659 (RL3_MOUSE)

Entry version 170 (29 Sep 2021)
Sequence version 3 (27 Jul 2011)
Previous versions | rss
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Protein

60S ribosomal protein L3

Gene

Rpl3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

The L3 protein is a component of the large subunit of cytoplasmic ribosomes.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-MMU-1799339, SRP-dependent cotranslational protein targeting to membrane
R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-MMU-72689, Formation of a pool of free 40S subunits
R-MMU-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-MMU-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-MMU-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
60S ribosomal protein L3
Alternative name(s):
J1 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Rpl3
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1351605, Rpl3

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000060036

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000772291 – 40360S ribosomal protein L3Add BLAST403

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei13PhosphoserineCombined sources1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki39Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei136N6-acetyllysineCombined sources1
Cross-linki224Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki226Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei245Tele-methylhistidineBy similarity1
Modified residuei286N6-acetyllysine; alternateCombined sources1
Cross-linki286Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Modified residuei294N6-acetyllysine; alternateBy similarity1
Cross-linki294Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Modified residuei304PhosphoserineBy similarity1
Modified residuei366N6-acetyllysine; alternateBy similarity1
Cross-linki366Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Modified residuei373N6-acetyllysineCombined sources1
Cross-linki386Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki393Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki399Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Constitutively monomethylated at His-245 by METTL18. Regulates the function of RPL3 in the dynamics of pre-rRNA processing, ribosome biogenesis, and translation. It is not required for incorporation of RPL3 into ribosomes.By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P27659

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P27659

MaxQB - The MaxQuant DataBase

More...MaxQBi		P27659

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P27659

PeptideAtlas

More...PeptideAtlasi		P27659

PRoteomics IDEntifications database

More...PRIDEi		P27659

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		299902

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		P27659

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		P27659

SwissPalm database of S-palmitoylation events

More...SwissPalmi		P27659

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000060036, Expressed in ventricular zone and 102 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		P27659, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		P27659, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the large ribosomal subunit.

Interacts with DHX33 (PubMed:26100019).

By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		205174, 88 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-5262, 60S cytosolic large ribosomal subunit

CORUM comprehensive resource of mammalian protein complexes

More...CORUMi		P27659

Protein interaction database and analysis system

More...IntActi		P27659, 3 interactors

Molecular INTeraction database

More...MINTi		P27659

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000080354

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		P27659, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P27659

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 36DisorderedSequence analysisAdd BLAST36

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the universal ribosomal protein uL3 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0746, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000017606

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_033361_2_1_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P27659

Identification of Orthologs from Complete Genome Data

More...OMAi		HQRTEYN

Database of Orthologous Groups

More...OrthoDBi		793191at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		P27659

TreeFam database of animal gene trees

More...TreeFami		TF300555

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000597, Ribosomal_L3
IPR019926, Ribosomal_L3_CS
IPR009000, Transl_B-barrel_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00297, Ribosomal_L3, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50447, SSF50447, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00474, RIBOSOMAL_L3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

P27659-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDASKP VHLTAFLGYK 
        60         70         80         90        100
AGMTHIVREV DRPGSKVNKK EVVEAVTIVE TPPMVVVGIV GYVETPRGLR 
       110        120        130        140        150
TFKTVFAEHI SDECKRRFYK NWHKSKKKAF TKYCKKWQDD TGKKQLEKDF 
       160        170        180        190        200
NSMKKYCQVI RIIAHTQMRL LPLRQKKAHL MEIQVNGGTV AEKLDWARER 
       210        220        230        240        250
LEQQVPVNQV FGQDEMIDVI GVTKGKGYKG VTSRWHTKKL PRKTHRGLRK 
       260        270        280        290        300
VACIGAWHPA RVAFSVARAG QKGYHHRTEI NKKIYKIGQG YLIKDGKLIK 
       310        320        330        340        350
NNASTDYDLS DKSINPLGGF VHYGEVTNDF IMLKGCVVGT KKRVLTLRKS 
       360        370        380        390        400
LLVQTKRRAL EKIDLKFIDT TSKFGHGRFQ TMEEKKAFMG PLKKDRIAKE 

EGA
Length:403
Mass (Da):46,110
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i87AA82D9B2A8481E
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WNS0A0A087WNS0_MOUSE
60S ribosomal protein L3
Rpl3
180Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WQK0A0A087WQK0_MOUSE
60S ribosomal protein L3
Rpl3
188Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8VHN4A0A2R8VHN4_MOUSE
60S ribosomal protein L3
Rpl3
134Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti265S → T in CAA68370 (PubMed:2628163).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
Y00225 mRNA Translation: CAA68370.1
U89417 mRNA Translation: AAC36524.1
AK088993 mRNA Translation: BAC40691.1
AK144518 mRNA Translation: BAE25922.1
AK144816 mRNA Translation: BAE26078.1
AK146502 mRNA Translation: BAE27217.1
AK149494 mRNA Translation: BAE28917.1
AK151596 mRNA Translation: BAE30536.1
AK166433 mRNA Translation: BAE38773.1
AK166825 mRNA Translation: BAE39049.1
AK167787 mRNA Translation: BAE39818.1
AK167947 mRNA Translation: BAE39950.1
AK168040 mRNA Translation: BAE40022.1
AK168059 mRNA Translation: BAE40037.1
AK168126 mRNA Translation: BAE40095.1
AK168128 mRNA Translation: BAE40097.1
AK168224 mRNA Translation: BAE40178.1
AK168744 mRNA Translation: BAE40585.1
AK169060 mRNA Translation: BAE40848.1
AK169235 mRNA Translation: BAE41003.1
AK169321 mRNA Translation: BAE41075.1
AK170819 mRNA Translation: BAE42051.1
CH466550 Genomic DNA Translation: EDL04616.1
BC009655 mRNA Translation: AAH09655.1
BC083134 mRNA Translation: AAH83134.1
BC094059 mRNA Translation: AAH94059.1
BC158039 mRNA Translation: AAI58040.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS37144.1

NCBI Reference Sequences

More...RefSeqi		NP_038790.2, NM_013762.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000081650; ENSMUSP00000080354; ENSMUSG00000060036

Database of genes from NCBI RefSeq genomes

More...GeneIDi		27367

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:27367

UCSC genome browser

More...UCSCi		uc007wvb.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y00225 mRNA Translation: CAA68370.1
U89417 mRNA Translation: AAC36524.1
AK088993 mRNA Translation: BAC40691.1
AK144518 mRNA Translation: BAE25922.1
AK144816 mRNA Translation: BAE26078.1
AK146502 mRNA Translation: BAE27217.1
AK149494 mRNA Translation: BAE28917.1
AK151596 mRNA Translation: BAE30536.1
AK166433 mRNA Translation: BAE38773.1
AK166825 mRNA Translation: BAE39049.1
AK167787 mRNA Translation: BAE39818.1
AK167947 mRNA Translation: BAE39950.1
AK168040 mRNA Translation: BAE40022.1
AK168059 mRNA Translation: BAE40037.1
AK168126 mRNA Translation: BAE40095.1
AK168128 mRNA Translation: BAE40097.1
AK168224 mRNA Translation: BAE40178.1
AK168744 mRNA Translation: BAE40585.1
AK169060 mRNA Translation: BAE40848.1
AK169235 mRNA Translation: BAE41003.1
AK169321 mRNA Translation: BAE41075.1
AK170819 mRNA Translation: BAE42051.1
CH466550 Genomic DNA Translation: EDL04616.1
BC009655 mRNA Translation: AAH09655.1
BC083134 mRNA Translation: AAH83134.1
BC094059 mRNA Translation: AAH94059.1
BC158039 mRNA Translation: AAI58040.1
CCDSiCCDS37144.1
RefSeqiNP_038790.2, NM_013762.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6SWAelectron microscopy3.10B1-403[»]
SMRiP27659
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi205174, 88 interactors
ComplexPortaliCPX-5262, 60S cytosolic large ribosomal subunit
CORUMiP27659
IntActiP27659, 3 interactors
MINTiP27659
STRINGi10090.ENSMUSP00000080354

PTM databases

iPTMnetiP27659
PhosphoSitePlusiP27659
SwissPalmiP27659

Proteomic databases

EPDiP27659
jPOSTiP27659
MaxQBiP27659
PaxDbiP27659
PeptideAtlasiP27659
PRIDEiP27659
ProteomicsDBi299902

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		1245, 285 antibodies

The DNASU plasmid repository

More...DNASUi		27367

Genome annotation databases

EnsembliENSMUST00000081650; ENSMUSP00000080354; ENSMUSG00000060036
GeneIDi27367
KEGGimmu:27367
UCSCiuc007wvb.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		6122
MGIiMGI:1351605, Rpl3
VEuPathDBiHostDB:ENSMUSG00000060036

Phylogenomic databases

eggNOGiKOG0746, Eukaryota
GeneTreeiENSGT00390000017606
HOGENOMiCLU_033361_2_1_1
InParanoidiP27659
OMAiHQRTEYN
OrthoDBi793191at2759
PhylomeDBiP27659
TreeFamiTF300555

Enzyme and pathway databases

ReactomeiR-MMU-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-MMU-1799339, SRP-dependent cotranslational protein targeting to membrane
R-MMU-6791226, Major pathway of rRNA processing in the nucleolus and cytosol
R-MMU-72689, Formation of a pool of free 40S subunits
R-MMU-72706, GTP hydrolysis and joining of the 60S ribosomal subunit
R-MMU-975956, Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
R-MMU-975957, Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		27367, 22 hits in 42 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Rpl3, mouse

Protein Ontology

More...PROi		PR:P27659
RNActiP27659, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000060036, Expressed in ventricular zone and 102 other tissues
ExpressionAtlasiP27659, baseline and differential
GenevisibleiP27659, MM

Family and domain databases

InterProiView protein in InterPro
IPR000597, Ribosomal_L3
IPR019926, Ribosomal_L3_CS
IPR009000, Transl_B-barrel_sf
PfamiView protein in Pfam
PF00297, Ribosomal_L3, 1 hit
SUPFAMiSSF50447, SSF50447, 1 hit
PROSITEiView protein in PROSITE
PS00474, RIBOSOMAL_L3, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL3_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P27659
Secondary accession number(s): O89071, Q91VJ6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: July 27, 2011
Last modified: September 29, 2021
This is version 170 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
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