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UniProtKB - P27309 (NUSG_STRVG)
Protein
Transcription termination/antitermination protein NusG
Gene
nusG
Organism
Streptomyces virginiae
Status
Functioni
Participates in transcription elongation, termination and antitermination.
UniRule annotationGO - Biological processi
- DNA-templated transcription, elongation Source: UniProtKB-UniRule
- DNA-templated transcription, termination Source: UniProtKB-UniRule
- regulation of DNA-templated transcription, elongation Source: InterPro
- transcription antitermination Source: UniProtKB-UniRule
Keywordsi
Biological process | Transcription, Transcription antitermination, Transcription regulation, Transcription termination |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription termination/antitermination protein NusGUniRule annotationAlternative name(s): Butanolide receptor |
Gene namesi | Name:nusGUniRule annotation Synonyms:vbrA |
Organismi | Streptomyces virginiae |
Taxonomic identifieri | 1961 [NCBI] |
Taxonomic lineagei | Bacteria › Actinobacteria › Streptomycetales › Streptomycetaceae › Streptomyces › Streptomyces virginiae group |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000113963 | 1 – 299 | Transcription termination/antitermination protein NusGAdd BLAST | 299 |
Post-translational modificationi
The N-terminus is blocked.
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 46 – 49 | 1 | 4 | |
Repeati | 70 – 73 | 2 | 4 | |
Repeati | 80 – 83 | 3; approximate | 4 | |
Repeati | 84 – 87 | 4 | 4 | |
Domaini | 248 – 276 | KOWUniRule annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 30 – 96 | DisorderedSequence analysisAdd BLAST | 67 | |
Regioni | 46 – 87 | 4 X 4 AA repeats of E-E-A-AAdd BLAST | 42 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 51 – 89 | Acidic residuesSequence analysisAdd BLAST | 39 |
Sequence similaritiesi
Belongs to the NusG family.UniRule annotation
Keywords - Domaini
RepeatFamily and domain databases
Gene3Di | 2.30.30.30, 1 hit 3.30.70.940, 1 hit |
HAMAPi | MF_00948, NusG, 1 hit |
InterProi | View protein in InterPro IPR005824, KOW IPR006645, NGN_dom IPR036735, NGN_dom_sf IPR043425, NusG-like IPR014722, Rib_L2_dom2 IPR001062, Transcrpt_antiterm_NusG IPR015869, Transcrpt_antiterm_NusG_bac_CS IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR30265, PTHR30265, 1 hit PTHR30265:SF2, PTHR30265:SF2, 1 hit |
Pfami | View protein in Pfam PF02357, NusG, 1 hit |
PRINTSi | PR00338, NUSGTNSCPFCT |
SMARTi | View protein in SMART SM00739, KOW, 1 hit SM00738, NGN, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit SSF82679, SSF82679, 1 hit |
TIGRFAMsi | TIGR00922, nusG, 1 hit |
PROSITEi | View protein in PROSITE PS01014, NUSG, 1 hit |
i Sequence
Sequence statusi: Complete.
P27309-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDPNLNASH DSVESVEDEL DIVEAADAVD PDEAELADAE AGAPAEEAAL
60 70 80 90 100
HVESDEDEDE ADVEVDAAVE EAADDAEVAE EEAEEAAPVE PAEPVDPIQA
110 120 130 140 150
LREELRLLPG EWYVIHTYAG YEKRVKANLE QRAVSLNVEE FIYQAEVPEE
160 170 180 190 200
EIVQIKNGER KNVRQNKLPG YVLVRMDLTN ESWGVVRNTP GVTGFVGNAY
210 220 230 240 250
DPYPLTLDEI VKMLAPEAQE KAAKAAAEEA GLPAPAVKRT IEVLDFEVGD
260 270 280 290
SVTVTDGPFA TLQATINEIN PDSKKVKGLV EIFGRETPVE LSFDQIQKN
Sequence cautioni
The sequence BAA01261 differs from that shown. Reason: Erroneous initiation.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D10468 Genomic DNA Translation: BAA01261.1 Different initiation. D50624 Genomic DNA Translation: BAA09301.1 |
PIRi | A41773 |
RefSeqi | WP_033225042.1, NZ_JNYC01000038.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D10468 Genomic DNA Translation: BAA01261.1 Different initiation. D50624 Genomic DNA Translation: BAA09301.1 |
PIRi | A41773 |
RefSeqi | WP_033225042.1, NZ_JNYC01000038.1 |
3D structure databases
SMRi | P27309 |
ModBasei | Search... |
Family and domain databases
Gene3Di | 2.30.30.30, 1 hit 3.30.70.940, 1 hit |
HAMAPi | MF_00948, NusG, 1 hit |
InterProi | View protein in InterPro IPR005824, KOW IPR006645, NGN_dom IPR036735, NGN_dom_sf IPR043425, NusG-like IPR014722, Rib_L2_dom2 IPR001062, Transcrpt_antiterm_NusG IPR015869, Transcrpt_antiterm_NusG_bac_CS IPR008991, Translation_prot_SH3-like_sf |
PANTHERi | PTHR30265, PTHR30265, 1 hit PTHR30265:SF2, PTHR30265:SF2, 1 hit |
Pfami | View protein in Pfam PF02357, NusG, 1 hit |
PRINTSi | PR00338, NUSGTNSCPFCT |
SMARTi | View protein in SMART SM00739, KOW, 1 hit SM00738, NGN, 1 hit |
SUPFAMi | SSF50104, SSF50104, 1 hit SSF82679, SSF82679, 1 hit |
TIGRFAMsi | TIGR00922, nusG, 1 hit |
PROSITEi | View protein in PROSITE PS01014, NUSG, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NUSG_STRVG | |
Accessioni | P27309Primary (citable) accession number: P27309 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 1, 1992 |
Last sequence update: | October 1, 1996 | |
Last modified: | September 29, 2021 | |
This is version 93 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencingDocuments
- SIMILARITY comments
Index of protein domains and families