We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - P27242 (WAAU_ECOLI)
Protein
Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
Gene
waaU
Organism
Escherichia coli (strain K12)
Status
Functioni
Adds the terminal N-acetyl-D-glucosamine group on the glucose(II) group of LPS.
Catalytic activityi
- UDP-N-acetyl-alpha-D-glucosamine + [lipopolysaccharide] = UDP + N-acetyl-alpha-D-glucosaminyl-[lipopolysaccharide]. EC:2.4.1.56
: LPS core biosynthesis Pathwayi
This protein is involved in the pathway LPS core biosynthesis, which is part of Bacterial outer membrane biogenesis.View all proteins of this organism that are known to be involved in the pathway LPS core biosynthesis and in Bacterial outer membrane biogenesis.
GO - Molecular functioni
- ADP-heptose-lipopolysaccharide heptosyltransferase activity Source: GO_Central
- lipopolysaccharide N-acetylglucosaminyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- lipopolysaccharide biosynthetic process Source: EcoCyc
- lipopolysaccharide core region biosynthetic process Source: GO_Central
Keywordsi
Molecular function | Glycosyltransferase, Transferase |
Biological process | Lipopolysaccharide biosynthesis |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11423-MONOMER |
UniPathwayi | UPA00958 |
Protein family/group databases
CAZyi | GT9, Glycosyltransferase Family 9 |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:waaU Synonyms:rfaK, waaK Ordered Locus Names:b3623, JW3598 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000097283 | 1 – 357 | Lipopolysaccharide 1,2-N-acetylglucosaminetransferaseAdd BLAST | 357 |
Proteomic databases
jPOSTi | P27242 |
PaxDbi | P27242 |
PRIDEi | P27242 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4263305, 249 interactors |
DIPi | DIP-10672N |
IntActi | P27242, 7 interactors |
STRINGi | 511145.b3623 |
Family & Domainsi
Phylogenomic databases
eggNOGi | COG0859, Bacteria |
HOGENOMi | CLU_056162_2_0_6 |
InParanoidi | P27242 |
PhylomeDBi | P27242 |
Family and domain databases
CDDi | cd03789, GT9_LPS_heptosyltransferase, 1 hit |
InterProi | View protein in InterPro IPR002201, Glyco_trans_9 |
Pfami | View protein in Pfam PF01075, Glyco_transf_9, 1 hit |
i Sequence
Sequence statusi: Complete.
P27242-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MRLGTFHKKK RFYINKIKIN FLSFLFRNKI NNQITDPAQV KSCLIIHDNN
60 70 80 90 100
KLGDLIVLSS IYRELYSKGV KITLLTNRKG GEFLSNNKNI FEFCIKESTG
110 120 130 140 150
FLEMLTLCKH LRDLQFDIVL DPFETMPSFK HSLILSSLKD SYILGFDHWY
160 170 180 190 200
KRYYSFYHPH DECLKEHMST RAIEILKHIY GEGKFSTNYD LHLPVDVEDK
210 220 230 240 250
IKEFIGDTRI VIINPLGAKK ICRLTFEQIK VIYQEVKTHF ENYRIIFTGL
260 270 280 290 300
PQDLLTIPIL EIETLPFDEF IYTVALTKYS DFVISVDTAL VHIAAAYHKP
310 320 330 340 350
TLAFYPNSRT PEYPSHLIWS PNHHKSIQIV SPTYTVKDID TETLTNSVKR
LSCIDKK
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 293 | I → M in AAA24523 (PubMed:1624462).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M95398 Genomic DNA Translation: AAA24523.1 U00039 Genomic DNA Translation: AAB18600.1 U00096 Genomic DNA Translation: AAC76647.1 AP009048 Genomic DNA Translation: BAE77669.1 |
PIRi | A65163 |
RefSeqi | NP_418080.1, NC_000913.3 WP_001236433.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC76647; AAC76647; b3623 BAE77669; BAE77669; BAE77669 |
GeneIDi | 948147 |
KEGGi | ecj:JW3598 eco:b3623 |
PATRICi | fig|511145.12.peg.3743 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M95398 Genomic DNA Translation: AAA24523.1 U00039 Genomic DNA Translation: AAB18600.1 U00096 Genomic DNA Translation: AAC76647.1 AP009048 Genomic DNA Translation: BAE77669.1 |
PIRi | A65163 |
RefSeqi | NP_418080.1, NC_000913.3 WP_001236433.1, NZ_LN832404.1 |
3D structure databases
SMRi | P27242 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 4263305, 249 interactors |
DIPi | DIP-10672N |
IntActi | P27242, 7 interactors |
STRINGi | 511145.b3623 |
Protein family/group databases
CAZyi | GT9, Glycosyltransferase Family 9 |
Proteomic databases
jPOSTi | P27242 |
PaxDbi | P27242 |
PRIDEi | P27242 |
Genome annotation databases
EnsemblBacteriai | AAC76647; AAC76647; b3623 BAE77669; BAE77669; BAE77669 |
GeneIDi | 948147 |
KEGGi | ecj:JW3598 eco:b3623 |
PATRICi | fig|511145.12.peg.3743 |
Organism-specific databases
EchoBASEi | EB1393 |
Phylogenomic databases
eggNOGi | COG0859, Bacteria |
HOGENOMi | CLU_056162_2_0_6 |
InParanoidi | P27242 |
PhylomeDBi | P27242 |
Enzyme and pathway databases
UniPathwayi | UPA00958 |
BioCyci | EcoCyc:EG11423-MONOMER |
Miscellaneous databases
PROi | PR:P27242 |
Family and domain databases
CDDi | cd03789, GT9_LPS_heptosyltransferase, 1 hit |
InterProi | View protein in InterPro IPR002201, Glyco_trans_9 |
Pfami | View protein in Pfam PF01075, Glyco_transf_9, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | WAAU_ECOLI | |
Accessioni | P27242Primary (citable) accession number: P27242 Secondary accession number(s): Q2M7T7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 1, 1992 |
Last sequence update: | October 1, 1994 | |
Last modified: | February 23, 2022 | |
This is version 145 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways