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Protein

Auracyanin-B

Gene

Caur_1950

Organism
Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probably a soluble electron acceptor for the integral membrane protein electron transfer alternative complex III (ACIII).1 Publication

Cofactori

Cu cationNote: Binds 1 copper ion per subunit.

Redox potential

E0 is +190 mV at pH 9, +215 mV at pH 7 and +240 mV at pH 4.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi152Copper1
Metal bindingi217Copper1
Metal bindingi222Copper1
Metal bindingi227Copper1

GO - Molecular functioni

  • copper ion binding Source: UniProtKB
  • electron transfer activity Source: InterPro

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport
LigandCopper, Metal-binding

Enzyme and pathway databases

BioCyciCAUR324602:G1GAO-1977-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Auracyanin-B
Short name:
Ac-B
Cleaved into the following 2 chains:
Gene namesi
Ordered Locus Names:Caur_1950
OrganismiChloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
Taxonomic identifieri324602 [NCBI]
Taxonomic lineageiBacteriaChloroflexiChloroflexiaChloroflexalesChloroflexineaeChloroflexaceaeChloroflexus
Proteomesi
  • UP000002008 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 56Sequence analysisAdd BLAST56
PropeptideiPRO_000000284657 – 801 PublicationAdd BLAST24
ChainiPRO_000000284781 – 235Auracyanin-B-1Add BLAST155
ChainiPRO_000000284889 – 235Auracyanin-B-2Add BLAST147

Post-translational modificationi

Glycosylated.1 Publication

Keywords - PTMi

Glycoprotein

Expressioni

Inductioni

Present in both photosynthetically (anaerobically) and dark (aerobic respiration) grown cells (at protein level) (PubMed:19190939). A later paper showed this protein to be present in both chemoheterotrophically (dark) and photoheterotrophically (light) grown cells, but with more protein present in light grown cells (PubMed:22249883). The second report is thought to be correct (PubMed:23357331).3 Publications

Interactioni

Protein-protein interaction databases

STRINGi324602.Caur_1950

Structurei

Secondary structure

1235
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP27197
SMRiP27197
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP27197

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini111 – 235Plastocyanin-likeAdd BLAST125

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105UTB Bacteria
COG3241 LUCA
HOGENOMiHOG000034233
InParanoidiP27197
OMAiHNWVLVN
OrthoDBiPOG091H0LOW

Family and domain databases

Gene3Di2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR000923 BlueCu_1
IPR028871 BlueCu_1_BS
IPR033138 Cu_oxidase_CS
IPR008972 Cupredoxin
PfamiView protein in Pfam
PF00127 Copper-bind, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
PROSITEiView protein in PROSITE
PS00196 COPPER_BLUE, 1 hit
PS00079 MULTICOPPER_OXIDASE1, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P27197-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSWRGSGRSN FRSRSSSNGG STFSGGSAGG PPLIVMMGLA FGAGLIMLIV
60 70 80 90 100
MIASNATAGG FVAATPRPTA TPRPTAAPAP TQPPAAQPTT APATQAANAP
110 120 130 140 150
GGSNVVNETP AQTVEVRAAP DALAFAQTSL SLPANTVVRL DFVNQNNLGV
160 170 180 190 200
QHNWVLVNGG DDVAAAVNTA AQNNADALFV PPPDTPNALA WTAMLNAGES
210 220 230
GSVTFRTPAP GTYLYICTFP GHYLAGMKGT LTVTP
Length:235
Mass (Da):23,716
Last modified:November 1, 1997 - v2
Checksum:i845186230C072521
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti183P → G AA sequence (PubMed:1313011).Curated1
Sequence conflicti186P → A AA sequence (PubMed:1313011).Curated1
Sequence conflicti219F → G AA sequence (PubMed:1313011).Curated1
Sequence conflicti223 – 226YLAG → TPI AA sequence (PubMed:1313011).Curated4

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78046 Genomic DNA Translation: AAB38318.1
CP000909 Genomic DNA Translation: ABY35165.1
RefSeqiWP_012257819.1, NC_010175.1
YP_001635554.1, NC_010175.1

Genome annotation databases

EnsemblBacteriaiABY35165; ABY35165; Caur_1950
GeneIDi5826401
KEGGicau:Caur_1950
PATRICifig|324602.8.peg.2219

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U78046 Genomic DNA Translation: AAB38318.1
CP000909 Genomic DNA Translation: ABY35165.1
RefSeqiWP_012257819.1, NC_010175.1
YP_001635554.1, NC_010175.1

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1OV8X-ray1.90A/B/C/D96-235[»]
1QHQX-ray1.55A96-235[»]
ProteinModelPortaliP27197
SMRiP27197
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi324602.Caur_1950

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABY35165; ABY35165; Caur_1950
GeneIDi5826401
KEGGicau:Caur_1950
PATRICifig|324602.8.peg.2219

Phylogenomic databases

eggNOGiENOG4105UTB Bacteria
COG3241 LUCA
HOGENOMiHOG000034233
InParanoidiP27197
OMAiHNWVLVN
OrthoDBiPOG091H0LOW

Enzyme and pathway databases

BioCyciCAUR324602:G1GAO-1977-MONOMER

Miscellaneous databases

EvolutionaryTraceiP27197

Family and domain databases

Gene3Di2.60.40.420, 1 hit
InterProiView protein in InterPro
IPR000923 BlueCu_1
IPR028871 BlueCu_1_BS
IPR033138 Cu_oxidase_CS
IPR008972 Cupredoxin
PfamiView protein in Pfam
PF00127 Copper-bind, 1 hit
SUPFAMiSSF49503 SSF49503, 1 hit
PROSITEiView protein in PROSITE
PS00196 COPPER_BLUE, 1 hit
PS00079 MULTICOPPER_OXIDASE1, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiAURB_CHLAA
AccessioniPrimary (citable) accession number: P27197
Secondary accession number(s): A9WE06, P94610
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: November 1, 1997
Last modified: February 28, 2018
This is version 122 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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