CHI4

Functionⁱ

Defense against chitin-containing fungal pathogens.

Catalytic activityⁱ

Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Active siteⁱ	132	Proton donorBy similarity		1

GO - Molecular functionⁱ

chitinase activity Source: UniProtKB-EC
chitin binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell wall macromolecule catabolic process Source: InterPro
chitin catabolic process Source: UniProtKB-KW
defense response Source: UniProtKB-KW
polysaccharide catabolic process Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Glycosidase, Hydrolase
Biological process	Carbohydrate metabolism, Chitin degradation, Plant defense, Polysaccharide degradation
Ligand	Chitin-binding

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	CBM18 Carbohydrate-Binding Module Family 18 GH19 Glycoside Hydrolase Family 19

CAZyⁱ

CBM18 Carbohydrate-Binding Module Family 18
GH19 Glycoside Hydrolase Family 19

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Endochitinase PR4 (EC:3.2.1.14)
Gene namesⁱ	Name:CHI4
Organismⁱ	Phaseolus vulgaris (Kidney bean) (French bean)
Taxonomic identifierⁱ	3885 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Streptophytina › Embryophyta › Tracheophyta › Euphyllophyta › Spermatophyta › Magnoliophyta › Mesangiospermae › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Fabales › Fabaceae › Papilionoideae › 50 kb inversion clade › NPAAA clade › indigoferoid/millettioid clade › Phaseoleae › Phaseolus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 23	Sequence analysisAdd BLAST		23
ChainⁱPRO_0000005315	24 – 270	Endochitinase PR4Add BLAST		247

Amino acid modifications

Feature key	Position(s)	DescriptionActions
Disulfide bondⁱ	26 ↔ 34	PROSITE-ProRule annotation
Disulfide bondⁱ	28 ↔ 40	PROSITE-ProRule annotation
Disulfide bondⁱ	33 ↔ 47	PROSITE-ProRule annotation
Disulfide bondⁱ	51 ↔ 56	PROSITE-ProRule annotation
Disulfide bondⁱ	88 ↔ 137	PROSITE-ProRule annotation
Disulfide bondⁱ	150 ↔ 160	PROSITE-ProRule annotation
Disulfide bondⁱ	238 ↔ 270	PROSITE-ProRule annotation

Keywords - PTMⁱ

Disulfide bond

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	P27054
SMRⁱ	P27054
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	24 – 58	Chitin-binding type-1PROSITE-ProRule annotationAdd BLAST		35

Sequence similaritiesⁱ

Belongs to the glycosyl hydrolase 19 family. Chitinase class I subfamily.Curated

Keywords - Domainⁱ

Signal

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00325 chitinase_glyco_hydro_19, 1 hit
Gene3Dⁱ	3.30.60.10, 1 hit
InterProⁱ	View protein in InterPro IPR001002 Chitin-bd_1 IPR018371 Chitin-binding_1_CS IPR036861 Endochitinase-like_sf IPR016283 Glyco_hydro_19 IPR000726 Glyco_hydro_19_cat IPR023346 Lysozyme-like_dom_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00187 Chitin_bind_1, 1 hit PF00182 Glyco_hydro_19, 2 hits
PIRSFⁱ	PIRSF001060 Endochitinase, 1 hit
PRINTSⁱ	PR00451 CHITINBINDNG
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD000609 Chitin_bd_1, 1 hit
SMARTⁱ	View protein in SMART SM00270 ChtBD1, 1 hit
SUPFAMⁱ	SSF53955 SSF53955, 1 hit SSF57016 SSF57016, 1 hit
PROSITEⁱ	View protein in PROSITE PS00026 CHIT_BIND_I_1, 1 hit PS50941 CHIT_BIND_I_2, 1 hit PS00773 CHITINASE_19_1, 1 hit PS00774 CHITINASE_19_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

P27054-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MGNKLVLVLV AVALVMGPKN VSAQNCGCAE GLCCSQYGYC GTGEDYCGTG 
        60         70         80         90        100
CQQGPCTTAS PPPSNNVNAD ILTADFLNGI IDQADSGCAG KNFYTRDAFL 
       110        120        130        140        150
SALNSYTDFG RVGSEDDSKR EIAAAFAHFT HETGHFCYIE EIDGASKDYC 
       160        170        180        190        200
DEESIAQYPC SSSKGYHGRG PIQLSWNFNY GPAGSANNFD GLGAPETVSN 
       210        220        230        240        250
DVVVSFKTAL WYWMQHVRPV INQGFGATIR AINGALECDG ANPTTVQARV 
       260        270
NYYTEYCRQL GVATGDNLTC

Length:270

Mass (Da):28,834

Last modified:August 1, 1992 - v1

Checksum:ⁱ033ECF32904622C1

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X57187 mRNA Translation: CAA40474.1
PIRⁱ	S16579

Protein	Similar proteins		Species	Score	Length	Source
P27054	Uncharacterized protein		PHAVU		271	UniRef90_P27054
endochitinase PR4		VIGRR		270
Uncharacterized protein		PHAAN		270
Chitinase class 4 (Fragment)		VIGUN		249

Protein	Similar proteins		Species	Score	Length	Source
P27054	Chitinase 6		ORYSJ		271	UniRef50_Q6K8R2
Uncharacterized protein		ORYGL		271
Uncharacterized protein		ORYRU		271
Uncharacterized protein		ORYNI		271
Uncharacterized protein		ORYSI		271
+220

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X57187 mRNA Translation: CAA40474.1
PIRⁱ	S16579

3D structure databases

ProteinModelPortalⁱ	P27054
SMRⁱ	P27054
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein family/group databases

CAZyⁱ	CBM18 Carbohydrate-Binding Module Family 18 GH19 Glycoside Hydrolase Family 19

CAZyⁱ

CBM18 Carbohydrate-Binding Module Family 18
GH19 Glycoside Hydrolase Family 19

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Family and domain databases

CDDⁱ	cd00325 chitinase_glyco_hydro_19, 1 hit
Gene3Dⁱ	3.30.60.10, 1 hit
InterProⁱ	View protein in InterPro IPR001002 Chitin-bd_1 IPR018371 Chitin-binding_1_CS IPR036861 Endochitinase-like_sf IPR016283 Glyco_hydro_19 IPR000726 Glyco_hydro_19_cat IPR023346 Lysozyme-like_dom_sf
Pfamⁱ	View protein in Pfam PF00187 Chitin_bind_1, 1 hit PF00182 Glyco_hydro_19, 2 hits
PIRSFⁱ	PIRSF001060 Endochitinase, 1 hit
PRINTSⁱ	PR00451 CHITINBINDNG
ProDomⁱ	View protein in ProDom or Entries sharing at least one domain PD000609 Chitin_bd_1, 1 hit
SMARTⁱ	View protein in SMART SM00270 ChtBD1, 1 hit
SUPFAMⁱ	SSF53955 SSF53955, 1 hit SSF57016 SSF57016, 1 hit
PROSITEⁱ	View protein in PROSITE PS00026 CHIT_BIND_I_1, 1 hit PS50941 CHIT_BIND_I_2, 1 hit PS00773 CHITINASE_19_1, 1 hit PS00774 CHITINASE_19_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CHI4_PHAVU
Accessionⁱ	P27054Primary (citable) accession number: P27054
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	August 1, 1992
	Last sequence update:	August 1, 1992
	Last modified:	October 10, 2018
	This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Plant Protein Annotation Program

Miscellaneousⁱ

Documents

Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries
SIMILARITY comments
Index of protein domains and families

UniProtKB - P27054 (CHI4_PHAVU)

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Endochitinase PR4

Select a section on the left to see content.

Functionⁱ

Catalytic activityⁱ

Sites

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Protein family/group databases

Names & Taxonomyⁱ

PTM / Processingⁱ

Molecule processing

Amino acid modifications

Keywords - PTMⁱ

Structureⁱ

3D structure databases

Family & Domainsⁱ

Domains and Repeats

Sequence similaritiesⁱ

Keywords - Domainⁱ

Family and domain databases

Sequenceⁱ

Sequence databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Documents

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - P27054 (CHI4_PHAVU)

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Endochitinase PR4

CHI4

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Family and domain databases

Sequence databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein family/group databases

Protocols and materials databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ