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Protein

Aspartate ammonia-lyase

Gene

ansB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-aspartate = fumarate + NH3.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei104SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase

Enzyme and pathway databases

BioCyciBSUB:BSU23570-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Aspartate ammonia-lyase (EC:4.3.1.1)
Short name:
Aspartase
Gene namesi
Name:ansB
Ordered Locus Names:BSU23570
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001613361 – 475Aspartate ammonia-lyaseAdd BLAST475

Proteomic databases

PaxDbiP26899
PRIDEiP26899

Interactioni

Subunit structurei

Homotetramer.

Protein-protein interaction databases

IntActiP26899, 2 interactors
STRINGi224308.Bsubs1_010100012936

Structurei

3D structure databases

ProteinModelPortaliP26899
SMRiP26899
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni143 – 145Substrate bindingBy similarity3

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4108IJ0 Bacteria
COG1027 LUCA
HOGENOMiHOG000061737
InParanoidiP26899
KOiK01744
OMAiEICENYV
PhylomeDBiP26899

Family and domain databases

Gene3Di1.10.275.10, 1 hit
InterProiView protein in InterPro
IPR004708 ApsA
IPR024083 Fumarase/histidase_N
IPR018951 Fumarase_C_C
IPR020557 Fumarate_lyase_CS
IPR000362 Fumarate_lyase_fam
IPR022761 Fumarate_lyase_N
IPR008948 L-Aspartase-like
PfamiView protein in Pfam
PF10415 FumaraseC_C, 1 hit
PF00206 Lyase_1, 1 hit
PRINTSiPR00149 FUMRATELYASE
SUPFAMiSSF48557 SSF48557, 1 hit
TIGRFAMsiTIGR00839 aspA, 1 hit
PROSITEiView protein in PROSITE
PS00163 FUMARATE_LYASES, 1 hit

Sequencei

Sequence statusi: Complete.

P26899-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNGQKEYRV EKDFLGEKQI EADVYYGIQT LRASENFPIT GYKIHEEMIN
60 70 80 90 100
ALAIVKKAAA LANMDVKRLY EGIGQAIVQA ADEILEGKWH DQFIVDPIQG
110 120 130 140 150
GAGTSMNMNA NEVIGNRALE IMGHKKGDYI HLSPNTHVNM SQSTNDVFPT
160 170 180 190 200
AIHISTLKLL EKLLKTMEDM HSVFKQKAQE FDSVIKMGRT HLQDAVPIRL
210 220 230 240 250
GQEFEAYSRV LERDIKRIKQ SRQHLYEVNM GATAVGTGLN ADPEYIKQVV
260 270 280 290 300
KHLADISGLP LVGADHLVDA TQNTDAYTEV SASLKVCMMN MSKIANDLRL
310 320 330 340 350
MASGPRAGLA EISLPARQPG SSIMPGKVNP VMAELINQIA FQVIGNDNTI
360 370 380 390 400
CLASEAGQLE LNVMEPVLVF NLLQSISIMN NGFRSFTDNC LKGIEANEKR
410 420 430 440 450
MKQYVEKSAG VITAVNPHLG YEAAARIARE AIMTGQSVRD LCLQHDVLTE
460 470
EELDIILNPY EMTKPGIAGK ELLEK
Length:475
Mass (Da):52,504
Last modified:July 7, 2009 - v2
Checksum:iF3E847DC83A81460
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti144T → Q in AAA22244 (PubMed:1711029).Curated1
Sequence conflicti144T → Q in BAA12643 (PubMed:8969508).Curated1
Sequence conflicti182D → H in AAA22244 (PubMed:1711029).Curated1
Sequence conflicti182D → H in BAA12643 (PubMed:8969508).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63264 Genomic DNA Translation: AAA22244.1
D84432 Genomic DNA Translation: BAA12643.1
AL009126 Genomic DNA Translation: CAB14289.2
PIRiB39440 UFBSD
RefSeqiNP_390238.2, NC_000964.3
WP_003230430.1, NZ_JNCM01000036.1

Genome annotation databases

EnsemblBacteriaiCAB14289; CAB14289; BSU23570
GeneIDi938721
KEGGibsu:BSU23570
PATRICifig|224308.179.peg.2569

Similar proteinsi

Entry informationi

Entry nameiASPA_BACSU
AccessioniPrimary (citable) accession number: P26899
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: July 7, 2009
Last modified: May 23, 2018
This is version 119 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

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