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Protein

Maltoporin

Gene

lamB

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in the transport of maltose and maltodextrins. Does not act as a receptor for phages.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei31Greasy slide, important in sugar transport1 Publication1
Sitei66Greasy slide, important in sugar transport1 Publication1
Sitei99Greasy slide, important in sugar transport1 Publication1
Sitei143Important in sugar transport1 Publication1
Sitei252Greasy slide, important in sugar transport1 Publication1
Sitei393Greasy slide, important in sugar transport1 Publication1
Sitei451Greasy slide, important in sugar transport1 Publication1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionPorin
Biological processIon transport, Sugar transport, Transport

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-4273-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Maltoporin
Alternative name(s):
Maltose-inducible porin
Gene namesi
Name:lamB
Synonyms:malL1 Publication
Ordered Locus Names:STM4231
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini26Periplasmic1 Publication1
Transmembranei27 – 35Beta stranded1 Publication9
Topological domaini36 – 64Extracellular1 PublicationAdd BLAST29
Transmembranei65 – 78Beta stranded1 PublicationAdd BLAST14
Topological domaini79 – 80Periplasmic1 Publication2
Transmembranei81 – 93Beta stranded1 PublicationAdd BLAST13
Topological domaini94 – 104Extracellular1 PublicationAdd BLAST11
Transmembranei105 – 115Beta stranded1 PublicationAdd BLAST11
Topological domaini116 – 122Periplasmic1 Publication7
Transmembranei123 – 130Beta stranded1 Publication8
Topological domaini131 – 148Extracellular1 PublicationAdd BLAST18
Transmembranei149 – 159Beta stranded1 PublicationAdd BLAST11
Topological domaini160 – 161Periplasmic1 Publication2
Transmembranei162 – 173Beta stranded1 PublicationAdd BLAST12
Topological domaini174 – 191Extracellular1 PublicationAdd BLAST18
Transmembranei192 – 205Beta stranded1 PublicationAdd BLAST14
Topological domaini206 – 209Periplasmic1 Publication4
Transmembranei210 – 222Beta stranded1 PublicationAdd BLAST13
Topological domaini223 – 234Extracellular1 PublicationAdd BLAST12
Transmembranei235 – 248Beta stranded1 PublicationAdd BLAST14
Topological domaini249 – 250Periplasmic1 Publication2
Transmembranei251 – 263Beta stranded1 PublicationAdd BLAST13
Topological domaini264 – 300Extracellular1 PublicationAdd BLAST37
Transmembranei301 – 315Beta stranded1 PublicationAdd BLAST15
Topological domaini316 – 317Periplasmic1 Publication2
Transmembranei318 – 333Beta stranded1 PublicationAdd BLAST16
Topological domaini334 – 336Extracellular1 Publication3
Transmembranei337 – 351Beta stranded1 PublicationAdd BLAST15
Topological domaini352 – 353Periplasmic1 Publication2
Transmembranei354 – 369Beta stranded1 PublicationAdd BLAST16
Topological domaini370 – 372Extracellular1 Publication3
Transmembranei373 – 388Beta stranded1 PublicationAdd BLAST16
Topological domaini389 – 395Periplasmic1 Publication7
Transmembranei396 – 410Beta stranded1 PublicationAdd BLAST15
Topological domaini411 – 436Extracellular1 PublicationAdd BLAST26
Transmembranei437 – 451Beta stranded1 PublicationAdd BLAST15
Topological domaini452Periplasmic1 Publication1

GO - Cellular componenti

Keywords - Cellular componenti

Cell outer membrane, Membrane

Pathology & Biotechi

Chemistry databases

DrugBankiDB02379 Beta-D-Glucose

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Add BLAST25
ChainiPRO_000002518026 – 452MaltoporinAdd BLAST427

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi47 ↔ 631 Publication

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiP26466
PRIDEiP26466

Expressioni

Inductioni

By maltose.Curated

Interactioni

Subunit structurei

Homotrimer formed of three 18-stranded antiparallel beta-barrels, containing three independent channels.1 Publication

Protein-protein interaction databases

STRINGi99287.STM4231

Structurei

Secondary structure

1452
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliP26466
SMRiP26466
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP26466

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni134 – 143Substrate1 Publication10

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane beta strand

Phylogenomic databases

eggNOGiENOG4108KDD Bacteria
COG4580 LUCA
HOGENOMiHOG000218083
KOiK02024
OMAiDYGRANA
PhylomeDBiP26466

Family and domain databases

CDDicd01346 Maltoporin-like, 1 hit
Gene3Di2.40.170.10, 1 hit
HAMAPiMF_01301 LamB, 1 hit
InterProiView protein in InterPro
IPR023738 Maltoporin
IPR003192 Porin_LamB
IPR036998 Porin_LamB_sf
PfamiView protein in Pfam
PF02264 LamB, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD008788 Porin_LamB, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P26466-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMITLRKLPL AVAVAAGVMS AQAMAVDFHG YARSGIGWTG SGGEQQCFQA
60 70 80 90 100
TGAQSKYRLG NECETYAELK LGQEVWKEGD KSFYFDTNVA YSVNQQNDWE
110 120 130 140 150
STDPAFREAN VQGKNLIEWL PGSTIWAGKR FYQRHDVHMI DFYYWDISGP
160 170 180 190 200
GAGIENIDLG FGKLSLAATR STEAGGSYTF SSQNIYDEVK DTANDVFDVR
210 220 230 240 250
LAGLQTNPDG VLELGVDYGR ANTTDGYKLA DGASKDGWMF TAEHTQSMLK
260 270 280 290 300
GYNKFVVQYA TDAMTTQGKG QARGSDGSSS FTEELSDGTK INYANKVINN
310 320 330 340 350
NGNMWRILDH GAISLGDKWD LMYVGMYQNI DWDNNLGTEW WTVGVRPMYK
360 370 380 390 400
WTPIMSTLLE VGYDNVKSQQ TGDRNNQYKI TLAQQWQAGD SIWSRPAIRI
410 420 430 440 450
FATYAKWDEK WGYIKDGDNI SRYAAATNSG ISTNSRGDSD EWTFGAQMEI

WW
Length:452
Mass (Da):50,549
Last modified:November 1, 1997 - v2
Checksum:iE5148050ECABF063
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54292 Genomic DNA Translation: CAA38187.1
AE006468 Genomic DNA Translation: AAL23055.1
PIRiA60177
RefSeqiNP_463096.1, NC_003197.2
WP_000973645.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaiAAL23055; AAL23055; STM4231
GeneIDi1255757
KEGGistm:STM4231
PATRICifig|99287.12.peg.4451

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X54292 Genomic DNA Translation: CAA38187.1
AE006468 Genomic DNA Translation: AAL23055.1
PIRiA60177
RefSeqiNP_463096.1, NC_003197.2
WP_000973645.1, NC_003197.2

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1MPRX-ray2.80A/B/C26-452[»]
2MPRX-ray2.40A/B/C26-452[»]
ProteinModelPortaliP26466
SMRiP26466
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM4231

Chemistry databases

DrugBankiDB02379 Beta-D-Glucose

Proteomic databases

PaxDbiP26466
PRIDEiP26466

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL23055; AAL23055; STM4231
GeneIDi1255757
KEGGistm:STM4231
PATRICifig|99287.12.peg.4451

Phylogenomic databases

eggNOGiENOG4108KDD Bacteria
COG4580 LUCA
HOGENOMiHOG000218083
KOiK02024
OMAiDYGRANA
PhylomeDBiP26466

Enzyme and pathway databases

BioCyciSENT99287:G1FZD-4273-MONOMER

Miscellaneous databases

EvolutionaryTraceiP26466

Family and domain databases

CDDicd01346 Maltoporin-like, 1 hit
Gene3Di2.40.170.10, 1 hit
HAMAPiMF_01301 LamB, 1 hit
InterProiView protein in InterPro
IPR023738 Maltoporin
IPR003192 Porin_LamB
IPR036998 Porin_LamB_sf
PfamiView protein in Pfam
PF02264 LamB, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD008788 Porin_LamB, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiLAMB_SALTY
AccessioniPrimary (citable) accession number: P26466
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1992
Last sequence update: November 1, 1997
Last modified: February 28, 2018
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
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Main funding by: National Institutes of Health

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