Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ferric enterobactin transport protein FepE

Gene

fepE

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the ferric enterobactin transport system.

GO - Molecular functioni

  • ferric-enterobactin transmembrane transporter activity Source: EcoCyc

GO - Biological processi

  • ferric-enterobactin transport Source: EcoCyc
  • iron ion homeostasis Source: UniProtKB-KW
  • lipopolysaccharide biosynthetic process Source: InterPro

Keywordsi

Biological processIon transport, Iron transport, Transport
LigandIron

Enzyme and pathway databases

BioCyciEcoCyc:EG10297-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ferric enterobactin transport protein FepE
Gene namesi
Name:fepE
Ordered Locus Names:b0587, JW0579
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10297 fepE

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 41CytoplasmicSequence analysisAdd BLAST41
Transmembranei42 – 62HelicalSequence analysisAdd BLAST21
Topological domaini63 – 338PeriplasmicSequence analysisAdd BLAST276
Transmembranei339 – 359HelicalSequence analysisAdd BLAST21
Topological domaini360 – 377CytoplasmicSequence analysisAdd BLAST18

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000872251 – 377Ferric enterobactin transport protein FepEAdd BLAST377

Proteomic databases

PaxDbiP26266
PRIDEiP26266

Expressioni

Inductioni

Repressed by H-NS, induced by LeuO. A monocistronic operon.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4259898, 146 interactors
DIPiDIP-9596N
IntActiP26266, 9 interactors
STRINGi316385.ECDH10B_0655

Structurei

3D structure databases

ProteinModelPortaliP26266
SMRiP26266
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the WzzB/Cld/Rol family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4108QY5 Bacteria
COG3765 LUCA
HOGENOMiHOG000117856
InParanoidiP26266
OMAiRKQDAVM
PhylomeDBiP26266

Family and domain databases

InterProiView protein in InterPro
IPR003856 LPS_length_determ_N_term
PfamiView protein in Pfam
PF02706 Wzz, 1 hit

Sequencei

Sequence statusi: Complete.

P26266-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSLNIKQGS DAHFPDYPLA SPSNNEIDLL NLISVLWRAK KTVMAVVFAF
60 70 80 90 100
ACAGLLISFI LPQKWTSAAV VTPPEPVQWQ ELEKSFTKLR VLDLDIKIDR
110 120 130 140 150
TEAFNLFIKK FQSVSLLEEY LRSSPYVMDQ LKEAKIDELD LHRAIVALSE
160 170 180 190 200
KMKAVDDNAS KKKDEPSLYT SWTLSFTAPT SEEAQTVLSG YIDYISTLVV
210 220 230 240 250
KESLENVRNK LEIKTQFEKE KLAQDRIKTK NQLDANIQRL NYSLDIANAA
260 270 280 290 300
GIKKPVYSNG QAVKDDPDFS ISLGADGIER KLEIEKAVTD VAELNGELRN
310 320 330 340 350
RQYLVEQLTK AHVNDVNFTP FKYQLSPSLP VKKDGPGKAI IVILSALIGG
360 370
MVACGGVLLR YAMASRKQDA MMADHLV
Length:377
Mass (Da):42,100
Last modified:October 1, 1993 - v2
Checksum:i1C81D51BBFC3A499
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74129 Genomic DNA Translation: CAA52226.1
U82598 Genomic DNA Translation: AAB40786.1
U00096 Genomic DNA Translation: AAC73688.1
AP009048 Genomic DNA Translation: BAE76342.1
M60177 Genomic DNA No translation available.
PIRiS34703
RefSeqiNP_415119.1, NC_000913.3
WP_000096692.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC73688; AAC73688; b0587
BAE76342; BAE76342; BAE76342
GeneIDi945180
KEGGiecj:JW0579
eco:b0587
PATRICifig|1411691.4.peg.1682

Entry informationi

Entry nameiFEPE_ECOLI
AccessioniPrimary (citable) accession number: P26266
Secondary accession number(s): Q2MBL4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: October 1, 1993
Last modified: March 28, 2018
This is version 124 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health