UniProtKB - P26039 (TLN1_MOUSE)
Talin-1
Tln1
Functioni
GO - Molecular functioni
- actin filament binding Source: InterPro
- integrin binding Source: CAFA
- LIM domain binding Source: MGI
- phosphatidylinositol binding Source: CAFA
- phosphatidylserine binding Source: CAFA
- structural constituent of cytoskeleton Source: InterPro
- vinculin binding Source: MGI
GO - Biological processi
- cell adhesion Source: InterPro
- cell-substrate junction assembly Source: MGI
- cortical actin cytoskeleton organization Source: MGI
- cytoskeletal anchoring at plasma membrane Source: InterPro
- integrin activation Source: CAFA
- integrin-mediated signaling pathway Source: CAFA
Enzyme and pathway databases
Reactomei | R-MMU-114608 Platelet degranulation R-MMU-354192 Integrin alphaIIb beta3 signaling R-MMU-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins R-MMU-372708 p130Cas linkage to MAPK signaling for integrins R-MMU-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-MMU-445355 Smooth Muscle Contraction R-MMU-5674135 MAP2K and MAPK activation |
Names & Taxonomyi
Protein namesi | Recommended name: Talin-1 |
Gene namesi | Name:Tln1 Synonyms:Tln |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1099832 Tln1 |
Subcellular locationi
Cytoskeleton
- cytoskeleton By similarity
Plasma membrane
- ruffle membrane By similarity; Peripheral membrane protein By similarity; Cytoplasmic side By similarity
Other locations
- Cell surface 1 Publication
- focal adhesion 1 Publication
Note: Colocalizes with LAYN at the membrane ruffles (By similarity). Localized preferentially in focal adhesions than fibrillar adhesions.By similarity
Cytoskeleton
- cytoskeleton Source: UniProtKB-SubCell
Plasma Membrane
- ruffle membrane Source: UniProtKB-SubCell
Other locations
- cell Source: GOC
- cell surface Source: UniProtKB-SubCell
- cytoplasm Source: UniProtKB-KW
- focal adhesion Source: MGI
- ruffle Source: HGNC-UCL
Keywords - Cellular componenti
Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000219429 | 1 – 2541 | Talin-1Add BLAST | 2541 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 167 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 405 | PhosphoserineBy similarity | 1 | |
Modified residuei | 425 | PhosphoserineCombined sources | 1 | |
Modified residuei | 446 | PhosphoserineCombined sources | 1 | |
Modified residuei | 620 | PhosphoserineCombined sources | 1 | |
Modified residuei | 729 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1021 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1116 | PhosphotyrosineCombined sources | 1 | |
Modified residuei | 1142 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 1201 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1225 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1263 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 1323 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1328 | PhosphoserineCombined sources | 1 | |
Modified residuei | 1544 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 1849 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1855 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 1878 | PhosphoserineCombined sources | 1 | |
Modified residuei | 2031 | N6-acetyllysineBy similarity | 1 | |
Modified residuei | 2040 | PhosphoserineCombined sources | 1 | |
Modified residuei | 2115 | N6-acetyllysineBy similarity | 1 |
Keywords - PTMi
Acetylation, PhosphoproteinProteomic databases
CPTACi | non-CPTAC-3676 |
EPDi | P26039 |
jPOSTi | P26039 |
MaxQBi | P26039 |
PaxDbi | P26039 |
PeptideAtlasi | P26039 |
PRIDEi | P26039 |
PTM databases
iPTMneti | P26039 |
PhosphoSitePlusi | P26039 |
SwissPalmi | P26039 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000028465 Expressed in 301 organ(s), highest expression level in bone marrow |
ExpressionAtlasi | P26039 baseline and differential |
Genevisiblei | P26039 MM |
Interactioni
Subunit structurei
Interacts with NRAP and LAYN (By similarity).
Interacts with SYNM (By similarity).
Interacts with ITGB1; the interaction is prevented by competitive binding of ITGB1BP1 (By similarity). Binds with high affinity to VCL and with low affinity to integrins (PubMed:23389036, PubMed:20610383, PubMed:15642262, PubMed:15272303).
Interacts with APBB1IP; this inhibits VCL binding (PubMed:23389036).
Interacts with PTK2/FAK1 (PubMed:7622520).
Interacts with PIP5K1C (PubMed:15623515).
Interacts with F-actin (PubMed:20610383).
By similarity6 PublicationsBinary interactionsi
GO - Molecular functioni
- actin filament binding Source: InterPro
- integrin binding Source: CAFA
- LIM domain binding Source: MGI
- vinculin binding Source: MGI
Protein-protein interaction databases
BioGridi | 204222, 8 interactors |
DIPi | DIP-647N |
IntActi | P26039, 22 interactors |
MINTi | P26039 |
STRINGi | 10090.ENSMUSP00000030187 |
Structurei
Secondary structure
3D structure databases
SMRi | P26039 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P26039 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 86 – 403 | FERMPROSITE-ProRule annotationAdd BLAST | 318 | |
Domaini | 2293 – 2533 | I/LWEQPROSITE-ProRule annotationAdd BLAST | 241 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 280 – 435 | Interaction with LAYNBy similarityAdd BLAST | 156 | |
Regioni | 1327 – 1948 | Interaction with SYNMBy similarityAdd BLAST | 622 | |
Regioni | 1359 – 1659 | Interaction with VCL and F-actin1 PublicationAdd BLAST | 301 |
Phylogenomic databases
eggNOGi | KOG4261 Eukaryota ENOG410XQ0V LUCA |
GeneTreei | ENSGT00940000157006 |
InParanoidi | P26039 |
KOi | K06271 |
OMAi | ISMETLH |
OrthoDBi | 9839at2759 |
TreeFami | TF314677 |
Family and domain databases
CDDi | cd14473 FERM_B-lobe, 1 hit cd12150 talin-RS, 1 hit |
DisProti | DP00653 |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR036723 Alpha-catenin/vinculin-like_sf IPR019749 Band_41_domain IPR014352 FERM/acyl-CoA-bd_prot_sf IPR035963 FERM_2 IPR019748 FERM_central IPR019747 FERM_CS IPR000299 FERM_domain IPR032425 FERM_f0 IPR018979 FERM_N IPR035964 I/LWEQ_dom_sf IPR002558 ILWEQ_dom IPR011993 PH-like_dom_sf IPR037438 Talin1/2-RS IPR015224 Talin_cent IPR036476 Talin_cent_sf IPR029071 Ubiquitin-like_domsf IPR015009 Vinculin-bd_dom |
Pfami | View protein in Pfam PF16511 FERM_f0, 1 hit PF00373 FERM_M, 1 hit PF09379 FERM_N, 1 hit PF01608 I_LWEQ, 1 hit PF09141 Talin_middle, 1 hit PF08913 VBS, 1 hit |
SMARTi | View protein in SMART SM00295 B41, 1 hit SM00307 ILWEQ, 1 hit |
SUPFAMi | SSF109880 SSF109880, 1 hit SSF109885 SSF109885, 4 hits SSF47031 SSF47031, 1 hit SSF47220 SSF47220, 5 hits SSF54236 SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS00660 FERM_1, 1 hit PS00661 FERM_2, 1 hit PS50057 FERM_3, 1 hit PS50945 I_LWEQ, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
10 20 30 40 50
MVALSLKISI GNVVKTMQFE PSTMVYDACR MIRERIPEAL AGPPNDFGLF
60 70 80 90 100
LSDDDPKKGI WLEAGKALDY YMLRNGDTME YRKKQRPLKI RMLDGTVKTI
110 120 130 140 150
MVDDSKTVTD MLMTICARIG ITNHDEYSLV RELMEEKKDE GTGTLRKDKT
160 170 180 190 200
LLRDEKKMEK LKQKLHTDDE LNWLDHGRTL REQGVEEHET LLLRRKFFYS
210 220 230 240 250
DQNVDSRDPV QLNLLYVQAR DDILNGSHPV SFDKACEFAG FQCQIQFGPH
260 270 280 290 300
NEQKHKAGFL DLKDFLPKEY VKQKGERKIF QAHKNCGQMS EIEAKVRYVK
310 320 330 340 350
LARSLKTYGV SFFLVKEKMK GKNKLVPRLL GITKECVMRV DEKTKEVIQE
360 370 380 390 400
WSLTNIKRWA ASPKSFTLDF GDYQDGYYSV QTTEGEQIAQ LIAGYIDIIL
410 420 430 440 450
KKKKSKDHFG LEGDEESTML EDSVSPKKST VLQQQYNRVG KVEHGSVALP
460 470 480 490 500
AIMRSGASGP ENFQVGSMPP AQQQITSGQM HRGHMPPLTS AQQALTGTIN
510 520 530 540 550
SSMQAVQAAQ ATLDDFETLP PLGQDAASKA WRKNKMDESK HEIHSQVDAI
560 570 580 590 600
TAGTASVVNL TAGDPAETDY TAVGCAVTTI SSNLTEMSRG VKLLAALLED
610 620 630 640 650
EGGNGRPLLQ AAKGLAGAVS ELLRSAQPAS AEPRQNLLQA AGNVGQASGE
660 670 680 690 700
LLQQIGESDT DPHFQDVLMQ LAKAVASAAA ALVLKAKSVA QRTEDSGLQT
710 720 730 740 750
QVIAAATQCA LSTSQLVACT KVVAPTISSP VCQEQLVEAG RLVAKAVEGC
760 770 780 790 800
VSASQAATED GQLLRGVGAA ATAVTQALNE LLQHVKAHAT GAGPAGRYDQ
810 820 830 840 850
ATDTILTVTE NIFSSMGDAG EMVRQARILA QATSDLVNAI KADAEGESDL
860 870 880 890 900
ENSRKLLSAA KILADATAKM VEAAKGAAAH PDSEEQQQRL REAAEGLRMA
910 920 930 940 950
TNAAAQNAIK KKLVQRLEHA AKQAAASATQ TIAAAQHAAS APKASAGPQP
960 970 980 990 1000
LLVQSCKAVA EQIPLLVQGV RGSQAQPDSP SAQLALIAAS QSFLQPGGKM
1010 1020 1030 1040 1050
VAAAKASVPT IQDQASAMQL SQCAKNLGTA LAELRTAAQK AQEACGPLEM
1060 1070 1080 1090 1100
DSALSVVQNL EKDLQEIKAA ARDGKLKPLP GETMEKCTQD LGNSTKAVSS
1110 1120 1130 1140 1150
AIAKLLGEIA QGNENYAGIA ARDVAGGLRS LAQAARGVAA LTSDPAVQAI
1160 1170 1180 1190 1200
VLDTASDVLD KASSLIEEAK KASGHPGDPE SQQRLAQVAK AVTQALNRCV
1210 1220 1230 1240 1250
SCLPGQRDVD NALRAVGDAS KRLLSDSLPP STGTFQEAQS RLNEAAAGLN
1260 1270 1280 1290 1300
QAATELVQAS RGTPQDLARA SGRFGQDFST FLEAGVEMAG QAPSQEDRAQ
1310 1320 1330 1340 1350
VVSNLKGISM SSSKLLLAAK ALSTDPASPN LKSQLAAAAR AVTDSINQLI
1360 1370 1380 1390 1400
TMCTQQAPGQ KECDNALRQL ETVRELLENP VQPINDMSYF GCLDSVMENS
1410 1420 1430 1440 1450
KVLGEAMTGI SQNAKNGNLP EFGDAIATAS KALCGFTEAA AQAAYLVGVS
1460 1470 1480 1490 1500
DPNSQAGQQG LVEPTQFARA NQAIQMACQS LGEPGCTQAQ VLSAATIVAK
1510 1520 1530 1540 1550
HTSALCNSCR LASARTANPT AKRQFVQSAK EVANSTANLV KTIKALDGDF
1560 1570 1580 1590 1600
TEENRAQCRA ATAPLLEAVD NLSAFASNPE FSSVPAQISP EGRAAMEPIV
1610 1620 1630 1640 1650
ISAKTMLESA GGLIQTARAL AVNPRDPPRW SVLAGHSRTV SDSIKKLITS
1660 1670 1680 1690 1700
MRDKAPGQLE CETAIAALNS CLRDLDQASL AAVSQQLAPR EGISQEALHT
1710 1720 1730 1740 1750
QMLTAVQEIS HLIEPLASAA RAEASQLGHK VSQMAQYFEP LTLAAVGAAS
1760 1770 1780 1790 1800
KTLSHPQQMA LLDQTKTLAE SALQLLYTAK EAGGNPKQAA HTQEALEEAV
1810 1820 1830 1840 1850
QMMTEAVEDL TTTLNEAASA AGVVGGMVDS ITQAINQLDE GPMGDPEGSF
1860 1870 1880 1890 1900
VDYQTTMVRT AKAIAVTVQE MVTKSNTSPE ELGPLANQLT SDYGRLASQA
1910 1920 1930 1940 1950
KPAAVAAENE EIGAHIKHRV QELGHGCSAL VTKAGALQCS PSDVYTKKEL
1960 1970 1980 1990 2000
IECARRVSEK VSHVLAALQA GNRGTQACIT AASAVSGIIA DLDTTIMFAT
2010 2020 2030 2040 2050
AGTLNREGAE TFADHREGIL KTAKVLVEDT KVLVQNAAGS QEKLAQAAQS
2060 2070 2080 2090 2100
SVATITRLAD VVKLGAASLG AEDPETQVVL INAVKDVAKA LGDLISATKA
2110 2120 2130 2140 2150
AAGKVGDDPA VWQLKNSAKV MVTNVTSLLK TVKAVEDEAT KGTRALEATT
2160 2170 2180 2190 2200
EHIRQELAVF CSPEPPAKTS TPEDFIRMTK GITMATAKAV AAGNSCRQED
2210 2220 2230 2240 2250
VIATANLSRR AIADMLRACK EAAFHPEVAP DVRLRALHYG RECANGYLEL
2260 2270 2280 2290 2300
LDHVLLTLQK PNPDLKQQLT GHSKRVAGSV TELIQAAEAM KGTEWVDPED
2310 2320 2330 2340 2350
PTVIAENELL GAAAAIEAAA KKLEQLKPRA KPKEADESLN FEEQILEAAK
2360 2370 2380 2390 2400
SIAAATSALV KAASAAQREL VAQGKVGAIP ANALDDGQWS QGLISAARMV
2410 2420 2430 2440 2450
AAATNNLCEA ANAAVQGHAS QEKLISSAKQ VAASTAQLLV ACKVKADQDS
2460 2470 2480 2490 2500
EAMKRLQAAG NAVKRASDNL VKAAQKAAAF EDQENETVVV KEKMVGGIAQ
2510 2520 2530 2540
IIAAQEEMLR KERELEEARK KLAQIRQQQY KFLPSELRDE H
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF6SX70 | F6SX70_MOUSE | Talin-1 | Tln1 | 279 | Annotation score: | ||
A2AIM2 | A2AIM2_MOUSE | Talin-1 | Tln1 | 241 | Annotation score: | ||
F6S1V7 | F6S1V7_MOUSE | Talin-1 | Tln1 | 122 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 673 | K → N in CAA39588 (PubMed:2120593).Curated | 1 | |
Sequence conflicti | 1227 | S → L in CAA39588 (PubMed:2120593).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural varianti | 1105 | L → P. | 1 | |
Natural varianti | 2180 | K → M. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X56123 mRNA Translation: CAA39588.1 AL732506 Genomic DNA No translation available. BC018557 mRNA Translation: AAH18557.1 BC150810 mRNA Translation: AAI50811.1 |
CCDSi | CCDS18101.1 |
PIRi | S11661 |
RefSeqi | NP_035732.2, NM_011602.5 XP_006537832.2, XM_006537769.3 |
Genome annotation databases
Ensembli | ENSMUST00000030187; ENSMUSP00000030187; ENSMUSG00000028465 |
GeneIDi | 21894 |
KEGGi | mmu:21894 |
UCSCi | uc008sqe.2 mouse |
Keywords - Coding sequence diversityi
PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X56123 mRNA Translation: CAA39588.1 AL732506 Genomic DNA No translation available. BC018557 mRNA Translation: AAH18557.1 BC150810 mRNA Translation: AAI50811.1 |
CCDSi | CCDS18101.1 |
PIRi | S11661 |
RefSeqi | NP_035732.2, NM_011602.5 XP_006537832.2, XM_006537769.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1SJ7 | X-ray | 2.50 | A/B/C | 482-655 | [»] | |
1SJ8 | X-ray | 2.60 | A | 482-789 | [»] | |
1T01 | X-ray | 2.06 | B | 605-628 | [»] | |
1U89 | NMR | - | A | 755-889 | [»] | |
1XWX | model | - | A | 486-889 | [»] | |
1Y19 | X-ray | 2.60 | B/D/F/H/J/L | 209-410 | [»] | |
1ZW3 | X-ray | 3.30 | B | 1628-1652 | [»] | |
2B0H | NMR | - | A | 1843-1973 | [»] | |
2G35 | NMR | - | A | 305-404 | [»] | |
2JSW | NMR | - | A | 2300-2482 | [»] | |
2KBB | NMR | - | A | 1655-1822 | [»] | |
2KC1 | NMR | - | A | 1-85 | [»] | |
2KC2 | NMR | - | A | 86-202 | [»] | |
2KGX | NMR | - | A | 1655-1822 | [»] | |
B | 311-401 | [»] | ||||
2KMA | NMR | - | A | 1-202 | [»] | |
2KVP | NMR | - | A | 1815-1973 | [»] | |
2L10 | NMR | - | A | 1206-1357 | [»] | |
2L7A | NMR | - | A | 787-911 | [»] | |
2L7N | NMR | - | A | 1046-1207 | [»] | |
2LQG | NMR | - | A | 913-1044 | [»] | |
2QDQ | X-ray | 2.20 | A/B | 2494-2541 | [»] | |
2X0C | X-ray | 2.00 | A | 1359-1659 | [»] | |
3DYJ | X-ray | 1.85 | A/B | 1974-2293 | [»] | |
3IVF | X-ray | 1.94 | A | 1-400 | [»] | |
3S90 | X-ray | 1.97 | C/D | 1512-1546 | [»] | |
4F7G | X-ray | 2.05 | A | 206-405 | [»] | |
B | 1654-1847 | [»] | ||||
4W8P | X-ray | 1.50 | A | 1357-1657 | [»] | |
5FZT | X-ray | 2.10 | A | 1359-1659 | [»] | |
5IC0 | X-ray | 1.97 | A | 1357-1822 | [»] | |
5IC1 | X-ray | 2.20 | A | 1357-1822 | [»] | |
5NL1 | X-ray | 2.50 | A/B/C/D/E/F | 480-635 | [»] | |
6BA6 | NMR | - | A | 1-86 | [»] | |
6MFS | X-ray | 2.85 | A | 1-136 | [»] | |
A | 169-400 | [»] | ||||
SMRi | P26039 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGridi | 204222, 8 interactors |
DIPi | DIP-647N |
IntActi | P26039, 22 interactors |
MINTi | P26039 |
STRINGi | 10090.ENSMUSP00000030187 |
PTM databases
iPTMneti | P26039 |
PhosphoSitePlusi | P26039 |
SwissPalmi | P26039 |
Proteomic databases
CPTACi | non-CPTAC-3676 |
EPDi | P26039 |
jPOSTi | P26039 |
MaxQBi | P26039 |
PaxDbi | P26039 |
PeptideAtlasi | P26039 |
PRIDEi | P26039 |
Genome annotation databases
Ensembli | ENSMUST00000030187; ENSMUSP00000030187; ENSMUSG00000028465 |
GeneIDi | 21894 |
KEGGi | mmu:21894 |
UCSCi | uc008sqe.2 mouse |
Organism-specific databases
CTDi | 7094 |
MGIi | MGI:1099832 Tln1 |
Phylogenomic databases
eggNOGi | KOG4261 Eukaryota ENOG410XQ0V LUCA |
GeneTreei | ENSGT00940000157006 |
InParanoidi | P26039 |
KOi | K06271 |
OMAi | ISMETLH |
OrthoDBi | 9839at2759 |
TreeFami | TF314677 |
Enzyme and pathway databases
Reactomei | R-MMU-114608 Platelet degranulation R-MMU-354192 Integrin alphaIIb beta3 signaling R-MMU-354194 GRB2:SOS provides linkage to MAPK signaling for Integrins R-MMU-372708 p130Cas linkage to MAPK signaling for integrins R-MMU-399955 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion R-MMU-445355 Smooth Muscle Contraction R-MMU-5674135 MAP2K and MAPK activation |
Miscellaneous databases
ChiTaRSi | Tln1 mouse |
EvolutionaryTracei | P26039 |
PROi | PR:P26039 |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000028465 Expressed in 301 organ(s), highest expression level in bone marrow |
ExpressionAtlasi | P26039 baseline and differential |
Genevisiblei | P26039 MM |
Family and domain databases
CDDi | cd14473 FERM_B-lobe, 1 hit cd12150 talin-RS, 1 hit |
DisProti | DP00653 |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR036723 Alpha-catenin/vinculin-like_sf IPR019749 Band_41_domain IPR014352 FERM/acyl-CoA-bd_prot_sf IPR035963 FERM_2 IPR019748 FERM_central IPR019747 FERM_CS IPR000299 FERM_domain IPR032425 FERM_f0 IPR018979 FERM_N IPR035964 I/LWEQ_dom_sf IPR002558 ILWEQ_dom IPR011993 PH-like_dom_sf IPR037438 Talin1/2-RS IPR015224 Talin_cent IPR036476 Talin_cent_sf IPR029071 Ubiquitin-like_domsf IPR015009 Vinculin-bd_dom |
Pfami | View protein in Pfam PF16511 FERM_f0, 1 hit PF00373 FERM_M, 1 hit PF09379 FERM_N, 1 hit PF01608 I_LWEQ, 1 hit PF09141 Talin_middle, 1 hit PF08913 VBS, 1 hit |
SMARTi | View protein in SMART SM00295 B41, 1 hit SM00307 ILWEQ, 1 hit |
SUPFAMi | SSF109880 SSF109880, 1 hit SSF109885 SSF109885, 4 hits SSF47031 SSF47031, 1 hit SSF47220 SSF47220, 5 hits SSF54236 SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS00660 FERM_1, 1 hit PS00661 FERM_2, 1 hit PS50057 FERM_3, 1 hit PS50945 I_LWEQ, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TLN1_MOUSE | |
Accessioni | P26039Primary (citable) accession number: P26039 Secondary accession number(s): A2AIM8, Q8VEF0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1992 |
Last sequence update: | July 27, 2011 | |
Last modified: | November 13, 2019 | |
This is version 197 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Complete proteome, Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references