UniProtKB - P26010 (ITB7_HUMAN)
Integrin beta-7
ITGB7
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 159 | Magnesium; MIDAS motifBy similarity | 1 | |
Metal bindingi | 161 | Magnesium; MIDAS motifBy similarity | 1 | |
Metal bindingi | 163 | Magnesium; MIDAS motifBy similarity | 1 | |
Metal bindingi | 166 | Magnesium or calcium; ADMIDAS motifBy similarity | 1 | |
Metal bindingi | 167 | Magnesium or calcium; ADMIDAS motifBy similarity | 1 | |
Metal bindingi | 198 | Magnesium; LIMBS motifBy similarity | 1 | |
Metal bindingi | 254 | Magnesium; LIMBS motifBy similarity | 1 | |
Metal bindingi | 256 | Magnesium; LIMBS motifBy similarity | 1 | |
Metal bindingi | 259 | Magnesium; LIMBS motifBy similarity | 1 | |
Metal bindingi | 289 | Magnesium; MIDAS motifBy similarity | 1 |
GO - Molecular functioni
- cell adhesion molecule binding Source: UniProtKB
- integrin binding Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- signaling receptor activity Source: InterPro
- virus receptor activity Source: UniProtKB-KW
GO - Biological processi
- cell adhesion Source: ProtInc
- cell adhesion mediated by integrin Source: GO_Central
- cell-matrix adhesion Source: UniProtKB
- cell-matrix adhesion involved in ameboidal cell migration Source: UniProtKB
- cell migration Source: GO_Central
- extracellular matrix organization Source: Reactome
- heterotypic cell-cell adhesion Source: UniProtKB
- integrin-mediated signaling pathway Source: UniProtKB
- leukocyte tethering or rolling Source: UniProtKB
- receptor clustering Source: UniProtKB
- regulation of immune response Source: Reactome
- substrate adhesion-dependent cell spreading Source: UniProtKB
- T cell migration Source: Ensembl
Keywordsi
Molecular function | Host cell receptor for virus entry, Integrin, Receptor |
Biological process | Cell adhesion |
Ligand | Magnesium, Metal-binding |
Enzyme and pathway databases
PathwayCommonsi | P26010 |
Reactomei | R-HSA-198933, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-216083, Integrin cell surface interactions |
SignaLinki | P26010 |
SIGNORi | P26010 |
Names & Taxonomyi
Protein namesi | Recommended name: Integrin beta-7Alternative name(s): Gut homing receptor beta subunit |
Gene namesi | Name:ITGB7 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000139626.15 |
HGNCi | HGNC:6162, ITGB7 |
MIMi | 147559, gene |
neXtProti | NX_P26010 |
Subcellular locationi
Other locations
Extracellular region or secreted
- extracellular exosome Source: UniProtKB
Plasma Membrane
- integrin alpha4-beta7 complex Source: UniProtKB
- integrin complex Source: ProtInc
- plasma membrane Source: Reactome
Other locations
- cell surface Source: UniProtKB
- focal adhesion Source: GO_Central
- membrane Source: UniProtKB
- receptor complex Source: MGI
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 20 – 723 | ExtracellularSequence analysisAdd BLAST | 704 | |
Transmembranei | 724 – 746 | HelicalSequence analysisAdd BLAST | 23 | |
Topological domaini | 747 – 798 | CytoplasmicSequence analysisAdd BLAST | 52 |
Keywords - Cellular componenti
MembranePathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 159 | D → A: Loss of integrin alpha-E/beta-7 binding to E-cadherin and of integrin alpha-4/beta-7 binding to MADCAM1. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 3695 |
OpenTargetsi | ENSG00000139626 |
PharmGKBi | PA29961 |
Miscellaneous databases
Pharosi | P26010, Tclin |
Chemistry databases
ChEMBLi | CHEMBL2979 |
DrugBanki | DB05122, R1295 DB09033, Vedolizumab |
DrugCentrali | P26010 |
GuidetoPHARMACOLOGYi | 2461 |
Polymorphism and mutation databases
BioMutai | ITGB7 |
DMDMi | 124973 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | 2 PublicationsAdd BLAST | 19 | |
ChainiPRO_0000016352 | 20 – 798 | Integrin beta-7Add BLAST | 779 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 45 ↔ 476 | By similarity | ||
Disulfide bondi | 51 ↔ 61 | By similarity | ||
Disulfide bondi | 54 ↔ 91 | By similarity | ||
Disulfide bondi | 64 ↔ 80 | By similarity | ||
Glycosylationi | 68 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 216 ↔ 223 | By similarity | ||
Disulfide bondi | 271 ↔ 311 | By similarity | ||
Glycosylationi | 279 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 412 ↔ 428 | By similarity | ||
Glycosylationi | 434 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 448 ↔ 688 | By similarity | ||
Disulfide bondi | 474 ↔ 478 | By similarity | ||
Glycosylationi | 477 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 488 ↔ 500 | By similarity | ||
Disulfide bondi | 497 ↔ 537 | By similarity | ||
Disulfide bondi | 502 ↔ 511 | By similarity | ||
Disulfide bondi | 513 ↔ 527 | By similarity | ||
Glycosylationi | 531 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 543 ↔ 548 | By similarity | ||
Disulfide bondi | 545 ↔ 574 | By similarity | ||
Disulfide bondi | 550 ↔ 559 | By similarity | ||
Disulfide bondi | 561 ↔ 566 | By similarity | ||
Disulfide bondi | 580 ↔ 585 | By similarity | ||
Disulfide bondi | 582 ↔ 613 | By similarity | ||
Disulfide bondi | 587 ↔ 596 | By similarity | ||
Glycosylationi | 590 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 598 ↔ 605 | By similarity | ||
Disulfide bondi | 619 ↔ 624 | By similarity | ||
Disulfide bondi | 621 ↔ 666 | By similarity | ||
Disulfide bondi | 626 ↔ 635 | By similarity | ||
Disulfide bondi | 638 ↔ 641 | By similarity | ||
Disulfide bondi | 645 ↔ 654 | By similarity | ||
Glycosylationi | 665 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 674 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 778 | Phosphotyrosine; by Tyr-kinasesBy similarity | 1 |
Keywords - PTMi
Disulfide bond, Glycoprotein, PhosphoproteinProteomic databases
jPOSTi | P26010 |
MassIVEi | P26010 |
MaxQBi | P26010 |
PaxDbi | P26010 |
PeptideAtlasi | P26010 |
PRIDEi | P26010 |
ProteomicsDBi | 54307 [P26010-1] 54308 [P26010-2] |
PTM databases
GlyGeni | P26010, 8 sites |
iPTMneti | P26010 |
PhosphoSitePlusi | P26010 |
Expressioni
Tissue specificityi
Inductioni
Gene expression databases
Bgeei | ENSG00000139626, Expressed in granulocyte and 197 other tissues |
ExpressionAtlasi | P26010, baseline and differential |
Genevisiblei | P26010, HS |
Organism-specific databases
HPAi | ENSG00000139626, Tissue enhanced (blood, lymphoid tissue) |
Interactioni
Subunit structurei
Heterodimer of an alpha and a beta subunit. Beta-7 associates with either alpha-4 or alpha-E. Integrin alpha-4/beta-7 interacts with MADCAM1, VCAM1, fibronectin, and may also interact with HIV-1 gp120.
Interacts with FLNA (via filamin repeats 4, 9, 12, 17, 19, 21, and 23) (PubMed:19828450).
3 PublicationsBinary interactionsi
Hide detailsP26010
With | #Exp. | IntAct |
---|---|---|
FLNA [P21333] | 6 | EBI-702932,EBI-350432 |
ITGA4 [P13612] | 6 | EBI-702932,EBI-703044 |
Isoform Long [P26010-1]
With | #Exp. | IntAct |
---|---|---|
FLNA [P21333] | 2 | EBI-15944630,EBI-350432 |
GO - Molecular functioni
- cell adhesion molecule binding Source: UniProtKB
- integrin binding Source: GO_Central
Protein-protein interaction databases
BioGRIDi | 109901, 13 interactors |
ComplexPortali | CPX-1823, Integrin alpha4-beta7 complex CPX-1824, Integrin alphaE-beta7 complex |
CORUMi | P26010 |
DIPi | DIP-34970N |
ELMi | P26010 |
IntActi | P26010, 3 interactors |
MINTi | P26010 |
STRINGi | 9606.ENSP00000267082 |
Chemistry databases
BindingDBi | P26010 |
Miscellaneous databases
RNActi | P26010, protein |
Structurei
Secondary structure
3D structure databases
BMRBi | P26010 |
SMRi | P26010 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P26010 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 150 – 389 | VWFAAdd BLAST | 240 | |
Repeati | 478 – 526 | IAdd BLAST | 49 | |
Repeati | 527 – 565 | IIAdd BLAST | 39 | |
Repeati | 566 – 604 | IIIAdd BLAST | 39 | |
Repeati | 605 – 640 | IVAdd BLAST | 36 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 478 – 640 | Cysteine-rich tandem repeatsAdd BLAST | 163 |
Domaini
Sequence similaritiesi
Keywords - Domaini
Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1226, Eukaryota |
GeneTreei | ENSGT01010000222340 |
HOGENOMi | CLU_011772_2_1_1 |
InParanoidi | P26010 |
OMAi | PLAANCS |
OrthoDBi | 473040at2759 |
PhylomeDBi | P26010 |
TreeFami | TF105392 |
Family and domain databases
Gene3Di | 3.40.50.410, 1 hit |
IDEALi | IID00616 |
InterProi | View protein in InterPro IPR013111, EGF_extracell IPR033760, Integrin_beta_N IPR015812, Integrin_bsu IPR015437, Integrin_bsu-7 IPR014836, Integrin_bsu_cyt_dom IPR012896, Integrin_bsu_tail IPR036349, Integrin_bsu_tail_dom_sf IPR002369, Integrin_bsu_VWA IPR032695, Integrin_dom_sf IPR016201, PSI IPR036465, vWFA_dom_sf |
PANTHERi | PTHR10082, PTHR10082, 1 hit PTHR10082:SF36, PTHR10082:SF36, 1 hit |
Pfami | View protein in Pfam PF07974, EGF_2, 1 hit PF08725, Integrin_b_cyt, 1 hit PF00362, Integrin_beta, 1 hit PF17205, PSI_integrin, 1 hit |
PIRSFi | PIRSF002512, Integrin_B, 1 hit |
PRINTSi | PR01186, INTEGRINB |
SMARTi | View protein in SMART SM00187, INB, 1 hit SM01241, Integrin_b_cyt, 1 hit SM01242, Integrin_B_tail, 1 hit SM00423, PSI, 1 hit |
SUPFAMi | SSF53300, SSF53300, 1 hit SSF69179, SSF69179, 1 hit SSF69687, SSF69687, 1 hit |
PROSITEi | View protein in PROSITE PS00022, EGF_1, 4 hits PS01186, EGF_2, 1 hit PS00243, INTEGRIN_BETA, 3 hits |
s (2+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 5 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MVALPMVLVL LLVLSRGESE LDAKIPSTGD ATEWRNPHLS MLGSCQPAPS
60 70 80 90 100
CQKCILSHPS CAWCKQLNFT ASGEAEARRC ARREELLARG CPLEELEEPR
110 120 130 140 150
GQQEVLQDQP LSQGARGEGA TQLAPQRVRV TLRPGEPQQL QVRFLRAEGY
160 170 180 190 200
PVDLYYLMDL SYSMKDDLER VRQLGHALLV RLQEVTHSVR IGFGSFVDKT
210 220 230 240 250
VLPFVSTVPS KLRHPCPTRL ERCQSPFSFH HVLSLTGDAQ AFEREVGRQS
260 270 280 290 300
VSGNLDSPEG GFDAILQAAL CQEQIGWRNV SRLLVFTSDD TFHTAGDGKL
310 320 330 340 350
GGIFMPSDGH CHLDSNGLYS RSTEFDYPSV GQVAQALSAA NIQPIFAVTS
360 370 380 390 400
AALPVYQELS KLIPKSAVGE LSEDSSNVVQ LIMDAYNSLS STVTLEHSSL
410 420 430 440 450
PPGVHISYES QCEGPEKREG KAEDRGQCNH VRINQTVTFW VSLQATHCLP
460 470 480 490 500
EPHLLRLRAL GFSEELIVEL HTLCDCNCSD TQPQAPHCSD GQGHLQCGVC
510 520 530 540 550
SCAPGRLGRL CECSVAELSS PDLESGCRAP NGTGPLCSGK GHCQCGRCSC
560 570 580 590 600
SGQSSGHLCE CDDASCERHE GILCGGFGRC QCGVCHCHAN RTGRACECSG
610 620 630 640 650
DMDSCISPEG GLCSGHGRCK CNRCQCLDGY YGALCDQCPG CKTPCERHRD
660 670 680 690 700
CAECGAFRTG PLATNCSTAC AHTNVTLALA PILDDGWCKE RTLDNQLFFF
710 720 730 740 750
LVEDDARGTV VLRVRPQEKG ADHTQAIVLG CVGGIVAVGL GLVLAYRLSV
760 770 780 790
EIYDRREYSR FEKEQQQLNW KQDSNPLYKS AITTTINPRF QEADSPTL
The sequence of this isoform differs from the canonical sequence as follows:
501-648: Missing.
Computationally mapped potential isoform sequencesi
There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF5H6T4 | F5H6T4_HUMAN | Integrin beta | ITGB7 | 471 | Annotation score: | ||
F8VNX4 | F8VNX4_HUMAN | Integrin beta-7 | ITGB7 | 158 | Annotation score: | ||
H3BRM2 | H3BRM2_HUMAN | Integrin beta-7 | ITGB7 | 93 | Annotation score: | ||
F8W186 | F8W186_HUMAN | Integrin beta-7 | ITGB7 | 88 | Annotation score: | ||
H3BRX4 | H3BRX4_HUMAN | Integrin beta-7 | ITGB7 | 117 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 34 | W → A AA sequence (PubMed:1750505).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_049637 | 672 | H → Y. Corresponds to variant dbSNP:rs11539433EnsemblClinVar. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_002753 | 501 – 648 | Missing in isoform Short. 1 PublicationAdd BLAST | 148 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M68892 mRNA Translation: AAA59184.1 S80335 mRNA Translation: AAB21332.1 M62880 mRNA Translation: AAA59185.1 L23823 , L23810, L23811, L23812, L23813, L23814, L23815, L23816, L23817, L23818, L23819, L23820, L23821, L23822 Genomic DNA Translation: AAA36118.1 S49378 , S49364, S49365, S49366, S49367, S49368, S49369, S49370, S49371, S49373, S49374, S49375, S49376, S49377 Genomic DNA Translation: AAB23688.1 BC015916 mRNA Translation: AAH15916.1 |
CCDSi | CCDS8849.1 [P26010-1] |
PIRi | A40526 |
RefSeqi | NP_000880.1, NM_000889.2 [P26010-1] XP_005268908.1, XM_005268851.3 [P26010-1] XP_005268909.1, XM_005268852.4 [P26010-1] |
Genome annotation databases
Ensembli | ENST00000267082; ENSP00000267082; ENSG00000139626 [P26010-1] ENST00000422257; ENSP00000408741; ENSG00000139626 [P26010-1] ENST00000550743; ENSP00000455374; ENSG00000139626 [P26010-2] |
GeneIDi | 3695 |
KEGGi | hsa:3695 |
UCSCi | uc001scc.4, human [P26010-1] |
Keywords - Coding sequence diversityi
Alternative splicing, PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M68892 mRNA Translation: AAA59184.1 S80335 mRNA Translation: AAB21332.1 M62880 mRNA Translation: AAA59185.1 L23823 , L23810, L23811, L23812, L23813, L23814, L23815, L23816, L23817, L23818, L23819, L23820, L23821, L23822 Genomic DNA Translation: AAA36118.1 S49378 , S49364, S49365, S49366, S49367, S49368, S49369, S49370, S49371, S49373, S49374, S49375, S49376, S49377 Genomic DNA Translation: AAB23688.1 BC015916 mRNA Translation: AAH15916.1 |
CCDSi | CCDS8849.1 [P26010-1] |
PIRi | A40526 |
RefSeqi | NP_000880.1, NM_000889.2 [P26010-1] XP_005268908.1, XM_005268851.3 [P26010-1] XP_005268909.1, XM_005268852.4 [P26010-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2BRQ | X-ray | 2.10 | C/D | 768-798 | [»] | |
3V4P | X-ray | 3.15 | B/D | 20-512 | [»] | |
3V4V | X-ray | 3.10 | B/D | 20-512 | [»] | |
BMRBi | P26010 | |||||
SMRi | P26010 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 109901, 13 interactors |
ComplexPortali | CPX-1823, Integrin alpha4-beta7 complex CPX-1824, Integrin alphaE-beta7 complex |
CORUMi | P26010 |
DIPi | DIP-34970N |
ELMi | P26010 |
IntActi | P26010, 3 interactors |
MINTi | P26010 |
STRINGi | 9606.ENSP00000267082 |
Chemistry databases
BindingDBi | P26010 |
ChEMBLi | CHEMBL2979 |
DrugBanki | DB05122, R1295 DB09033, Vedolizumab |
DrugCentrali | P26010 |
GuidetoPHARMACOLOGYi | 2461 |
PTM databases
GlyGeni | P26010, 8 sites |
iPTMneti | P26010 |
PhosphoSitePlusi | P26010 |
Polymorphism and mutation databases
BioMutai | ITGB7 |
DMDMi | 124973 |
Proteomic databases
jPOSTi | P26010 |
MassIVEi | P26010 |
MaxQBi | P26010 |
PaxDbi | P26010 |
PeptideAtlasi | P26010 |
PRIDEi | P26010 |
ProteomicsDBi | 54307 [P26010-1] 54308 [P26010-2] |
Protocols and materials databases
ABCDi | P26010, 4 sequenced antibodies |
Antibodypediai | 26942, 511 antibodies |
DNASUi | 3695 |
Genome annotation databases
Ensembli | ENST00000267082; ENSP00000267082; ENSG00000139626 [P26010-1] ENST00000422257; ENSP00000408741; ENSG00000139626 [P26010-1] ENST00000550743; ENSP00000455374; ENSG00000139626 [P26010-2] |
GeneIDi | 3695 |
KEGGi | hsa:3695 |
UCSCi | uc001scc.4, human [P26010-1] |
Organism-specific databases
CTDi | 3695 |
DisGeNETi | 3695 |
EuPathDBi | HostDB:ENSG00000139626.15 |
GeneCardsi | ITGB7 |
HGNCi | HGNC:6162, ITGB7 |
HPAi | ENSG00000139626, Tissue enhanced (blood, lymphoid tissue) |
MIMi | 147559, gene |
neXtProti | NX_P26010 |
OpenTargetsi | ENSG00000139626 |
PharmGKBi | PA29961 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1226, Eukaryota |
GeneTreei | ENSGT01010000222340 |
HOGENOMi | CLU_011772_2_1_1 |
InParanoidi | P26010 |
OMAi | PLAANCS |
OrthoDBi | 473040at2759 |
PhylomeDBi | P26010 |
TreeFami | TF105392 |
Enzyme and pathway databases
PathwayCommonsi | P26010 |
Reactomei | R-HSA-198933, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell R-HSA-216083, Integrin cell surface interactions |
SignaLinki | P26010 |
SIGNORi | P26010 |
Miscellaneous databases
BioGRID-ORCSi | 3695, 213 hits in 844 CRISPR screens |
ChiTaRSi | ITGB7, human |
EvolutionaryTracei | P26010 |
GeneWikii | ITGB7 |
GenomeRNAii | 3695 |
Pharosi | P26010, Tclin |
PROi | PR:P26010 |
RNActi | P26010, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000139626, Expressed in granulocyte and 197 other tissues |
ExpressionAtlasi | P26010, baseline and differential |
Genevisiblei | P26010, HS |
Family and domain databases
Gene3Di | 3.40.50.410, 1 hit |
IDEALi | IID00616 |
InterProi | View protein in InterPro IPR013111, EGF_extracell IPR033760, Integrin_beta_N IPR015812, Integrin_bsu IPR015437, Integrin_bsu-7 IPR014836, Integrin_bsu_cyt_dom IPR012896, Integrin_bsu_tail IPR036349, Integrin_bsu_tail_dom_sf IPR002369, Integrin_bsu_VWA IPR032695, Integrin_dom_sf IPR016201, PSI IPR036465, vWFA_dom_sf |
PANTHERi | PTHR10082, PTHR10082, 1 hit PTHR10082:SF36, PTHR10082:SF36, 1 hit |
Pfami | View protein in Pfam PF07974, EGF_2, 1 hit PF08725, Integrin_b_cyt, 1 hit PF00362, Integrin_beta, 1 hit PF17205, PSI_integrin, 1 hit |
PIRSFi | PIRSF002512, Integrin_B, 1 hit |
PRINTSi | PR01186, INTEGRINB |
SMARTi | View protein in SMART SM00187, INB, 1 hit SM01241, Integrin_b_cyt, 1 hit SM01242, Integrin_B_tail, 1 hit SM00423, PSI, 1 hit |
SUPFAMi | SSF53300, SSF53300, 1 hit SSF69179, SSF69179, 1 hit SSF69687, SSF69687, 1 hit |
PROSITEi | View protein in PROSITE PS00022, EGF_1, 4 hits PS01186, EGF_2, 1 hit PS00243, INTEGRIN_BETA, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | ITB7_HUMAN | |
Accessioni | P26010Primary (citable) accession number: P26010 Secondary accession number(s): Q9UCP7, Q9UCS7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1992 |
Last sequence update: | May 1, 1992 | |
Last modified: | December 2, 2020 | |
This is version 206 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 12
Human chromosome 12: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations