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UniProtKB - P25868 (UBC7_WHEAT)
Protein
Ubiquitin-conjugating enzyme E2 7
Gene
UBC7
Organism
Triticum aestivum (Wheat)
Status
Functioni
Catalyzes the covalent attachment of ubiquitin to other proteins so as to signal them for selective protein degradation. Involved in the formation of multiubiquitin chains.
PROSITE-ProRule annotation1 PublicationCatalytic activityi
- S-ubiquitinyl-[E1 ubiquitin-activating enzyme]-L-cysteine + [E2 ubiquitin-conjugating enzyme]-L-cysteine = [E1 ubiquitin-activating enzyme]-L-cysteine + S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine.PROSITE-ProRule annotation EC:2.3.2.23
: protein ubiquitination Pathwayi
This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.PROSITE-ProRule annotationView all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 92 | Glycyl thioester intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- ubiquitin conjugating enzyme activity Source: GO_Central
GO - Biological processi
- protein polyubiquitination Source: GO_Central
- ubiquitin-dependent protein catabolic process Source: GO_Central
Keywordsi
Molecular function | Transferase |
Biological process | Ubl conjugation pathway |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
UniPathwayi | UPA00143 |
Names & Taxonomyi
Protein namesi | Recommended name: Ubiquitin-conjugating enzyme E2 7 (EC:2.3.2.23)Alternative name(s): E2 ubiquitin-conjugating enzyme 7 Ubiquitin carrier protein 7 Ubiquitin-protein ligase 7 |
Gene namesi | Name:UBC7 |
Organismi | Triticum aestivum (Wheat) |
Taxonomic identifieri | 4565 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › Liliopsida › Poales › Poaceae › BOP clade › Pooideae › Triticodae › Triticeae › Triticinae › Triticum |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000082585 | 1 – 168 | Ubiquitin-conjugating enzyme E2 7Add BLAST | 168 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 166 | UBC corePROSITE-ProRule annotationAdd BLAST | 161 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 21 | DisorderedSequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the ubiquitin-conjugating enzyme family.PROSITE-ProRule annotation
Phylogenomic databases
eggNOGi | KOG0425, Eukaryota |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBC_1, 1 hit PS50127, UBC_2, 1 hit |
i Sequence
Sequence statusi: Complete.
P25868-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATAPARRAS SSRSSSEISR TTPSMGFQLG FVDDSNVFEW QVTIIGPPET
60 70 80 90 100
LYDGGYFNAI MSFPQNYPNS PPTVRFTSEM WHPNVYPDGR VCISIHPPGD
110 120 130 140 150
DPNGYELASE RWTPVHTVES IVLSIISMLS SPNDESPANI EAAKDWREKQ
160
DEFKKKVRRA VRKSQEML
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M74077 mRNA No translation available. |
PIRi | A41547 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M74077 mRNA No translation available. |
PIRi | A41547 |
3D structure databases
AlphaFoldDBi | P25868 |
SMRi | P25868 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 4565.Traes_3B_6707B51E1.1 |
Phylogenomic databases
eggNOGi | KOG0425, Eukaryota |
Enzyme and pathway databases
UniPathwayi | UPA00143 |
Gene expression databases
ExpressionAtlasi | P25868, baseline |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBC_1, 1 hit PS50127, UBC_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | UBC7_WHEAT | |
Accessioni | P25868Primary (citable) accession number: P25868 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1992 |
Last sequence update: | May 1, 1992 | |
Last modified: | May 25, 2022 | |
This is version 101 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families