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Entry version 127 (18 Sep 2019)
Sequence version 3 (15 Jul 1998)
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Protein

Light-sensor Protein kinase

Gene

PHY1

Organism
Ceratodon purpureus (Fire moss) (Dicranum purpureum)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei320Phytochromobilin chromophore (covalent; via 1 link)By similarity1
Binding sitei1031ATPPROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei1127By similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi1010 – 1018ATPPROSITE-ProRule annotation9

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinase, Photoreceptor protein, Receptor, Serine/threonine-protein kinase, Transferase
Biological processSensory transduction, Transcription, Transcription regulation
LigandATP-binding, Chromophore, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Light-sensor Protein kinase
Including the following 2 domains:
Phytochrome
Protein kinase (EC:2.7.11.1)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PHY1
Synonyms:PHY
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCeratodon purpureus (Fire moss) (Dicranum purpureum)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3225 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaBryophytaBryophytinaBryopsidaDicranidaePseudoditrichalesDitrichaceaeCeratodon

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001719701 – 1307Light-sensor Protein kinaseAdd BLAST1307

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Contains one covalently linked phytochromobilin chromophore.By similarity

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
P25848

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P25848

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini215 – 394GAFAdd BLAST180
Domaini609 – 680PASPROSITE-ProRule annotationAdd BLAST72
Domaini683 – 739PACPROSITE-ProRule annotationAdd BLAST57
Domaini1004 – 1307Protein kinasePROSITE-ProRule annotationAdd BLAST304

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni779 – 1003HingeAdd BLAST225

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the N-terminal section; belongs to the phytochrome family.Curated
In the C-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.Curated

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.450.40, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003018 GAF
IPR029016 GAF-like_dom_sf
IPR011009 Kinase-like_dom_sf
IPR000014 PAS
IPR000700 PAS-assoc_C
IPR035965 PAS-like_dom_sf
IPR013654 PAS_2
IPR013767 PAS_fold
IPR016132 Phyto_chromo_attachment
IPR013516 Phyto_chromo_BS
IPR001294 Phytochrome
IPR013515 Phytochrome_cen-reg
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008271 Ser/Thr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01590 GAF, 1 hit
PF00989 PAS, 1 hit
PF08446 PAS_2, 1 hit
PF00360 PHY, 1 hit
PF07714 Pkinase_Tyr, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01033 PHYTOCHROME

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00065 GAF, 1 hit
SM00091 PAS, 1 hit
SM00220 S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55785 SSF55785, 2 hits
SSF56112 SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50113 PAC, 1 hit
PS50112 PAS, 1 hit
PS00245 PHYTOCHROME_1, 1 hit
PS50046 PHYTOCHROME_2, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P25848-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSATKKTYSS TTSAKSKHSV RVAQTTADAA LEAVYEMSGD SGDSFDYSKS
60 70 80 90 100
VGQSAESVPA GAVTAYLQRM QREGLIQNFG CMVAVEEPNF CVIAYSENAS
110 120 130 140 150
EFLDLIPQAV PSMGEMDVLG IGTDIRTLFT PSSSAALEKA AATQDISLLN
160 170 180 190 200
PITVHCRRSG KPLYAIAHRI DIGIVIDFEA VKMIDVPVSA AAGALQSHKL
210 220 230 240 250
AARAITRLQA LPGGDIELLC DTIVEEVREL TGYDRVMAFK FHEDEHGEVV
260 270 280 290 300
AEIRRMDLEP YMGLHYPATD IPQASRFLLM KNRVRLIADC YASPVKLIQD
310 320 330 340 350
PDIRQPVSLA GSTLRAPHGC HAQYMGNMGS IASLVMAVII NDNEEYSRGA
360 370 380 390 400
IQRGRKLWGL VVCQHTSPRT VPFPLRSVCE FLMQVFGMQL NLHVELAAQL
410 420 430 440 450
REKHILRTQT LLCDMLLRDA PIGIVSQTPN IMDLVKCDGA ALYYGKRVWL
460 470 480 490 500
LGTTPTENQI KEIADWLLEH HNDSTGLSTD SLADANYPGA HLLGDAVCGM
510 520 530 540 550
AAAKITAKDF LFWFRSHTAT EVKWGGAKHD PDEKDDGRKM HPRSSFKAFL
560 570 580 590 600
EVVNKRSPPW EDVEMDAIHS LQLILRGSFR DIADSDTKTM IHARLNDLKL
610 620 630 640 650
QGVEERNALA NEMSRVLETA AAPILAVDSR GMINAWNAKI AQVTGLPVEE
660 670 680 690 700
AMHCSLTKDL VLDESVVVVE RLLSLALQGE EEQNVEIKLK TFGTQTTERA
710 720 730 740 750
VILIVNACCS RDASDFVVGV FFVGQDVTEQ RMFMDRFTRI QGGEKTTVQD
760 770 780 790 800
PHPLMRPSFD GDEFGRTFKR NSALGGLKDH ATGSVERLDL YLRRAEECME
810 820 830 840 850
VMETIPSPKF NNKQCQYLAG KLKAVLQSAS LFLRISHHEH HELGASIDMG
860 870 880 890 900
RHVEIFKLLL ALAKEIESFI QGCCKDEWIK AAMTLTNVSE YVSSMGFNLE
910 920 930 940 950
LCKIAFCKSC AASGSLTLDQ IEVICKDEAE VVKRNASIDV DTLFAKVIYD
960 970 980 990 1000
LTEKTLSSDQ NDLAIYLLQR LKRAKPILPS FSSRPSWWNF YDDWSFSEKF
1010 1020 1030 1040 1050
FQWIQITGSL GSGSSATVEK AVWLGTPVAK KTFYGRNNED FKREVEILAE
1060 1070 1080 1090 1100
LCHPNITSMF CSPLYRRKCS IIMELMDGDL LALMQRRLDR NEDHDSPPFS
1110 1120 1130 1140 1150
ILEVVDIILQ TSEGMNYLHE KGIIHRDLKS MNILVKSVKV TKSEIGYVHV
1160 1170 1180 1190 1200
KVADFGLSKT KDSSTRYSNQ TWNRGTNRWM APEVINLGYE STEGEISFDG
1210 1220 1230 1240 1250
KVPKYPLKSD VYSFGMVCYE VLTGDVPFPE EKNPNNVKRM VLEGVRPDLP
1260 1270 1280 1290 1300
AHCPIELKAL ITDCWNQDPL KRPSFAVICQ KLKYLKYLLM TGFSSYQDSY

PSTEEPS
Length:1,307
Mass (Da):145,844
Last modified:July 15, 1998 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE5E77A9FEF301A5C
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti513W → L in CAA34936 (PubMed:2261981).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U87632 Genomic DNA Translation: AAB47762.1
X17084 Genomic DNA Translation: CAA34936.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S27396

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U87632 Genomic DNA Translation: AAB47762.1
X17084 Genomic DNA Translation: CAA34936.1
PIRiS27396

3D structure databases

SMRiP25848
ModBaseiSearch...

Proteomic databases

PRIDEiP25848

Family and domain databases

Gene3Di3.30.450.40, 1 hit
InterProiView protein in InterPro
IPR003018 GAF
IPR029016 GAF-like_dom_sf
IPR011009 Kinase-like_dom_sf
IPR000014 PAS
IPR000700 PAS-assoc_C
IPR035965 PAS-like_dom_sf
IPR013654 PAS_2
IPR013767 PAS_fold
IPR016132 Phyto_chromo_attachment
IPR013516 Phyto_chromo_BS
IPR001294 Phytochrome
IPR013515 Phytochrome_cen-reg
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR001245 Ser-Thr/Tyr_kinase_cat_dom
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF01590 GAF, 1 hit
PF00989 PAS, 1 hit
PF08446 PAS_2, 1 hit
PF00360 PHY, 1 hit
PF07714 Pkinase_Tyr, 1 hit
PRINTSiPR01033 PHYTOCHROME
SMARTiView protein in SMART
SM00065 GAF, 1 hit
SM00091 PAS, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF55785 SSF55785, 2 hits
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50113 PAC, 1 hit
PS50112 PAS, 1 hit
PS00245 PHYTOCHROME_1, 1 hit
PS50046 PHYTOCHROME_2, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPHY1_CERPU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P25848
Secondary accession number(s): P93100
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: July 15, 1998
Last modified: September 18, 2019
This is version 127 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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