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UniProtKB - P25794 (PIP2_PEA)
Protein
Probable aquaporin PIP-type 7a
Gene
TRG-31
Organism
Pisum sativum (Garden pea)
Status
Functioni
Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
By similarityGO - Molecular functioni
- channel activity Source: InterPro
Keywordsi
Biological process | Stress response, Transport |
Protein family/group databases
TCDBi | 1.A.8.11.1, the major intrinsic protein (mip) family |
Names & Taxonomyi
Protein namesi | Recommended name: Probable aquaporin PIP-type 7aAlternative name(s): Turgor-responsive protein 31 Turgor-responsive protein 7a |
Gene namesi | Name:TRG-31 |
Organismi | Pisum sativum (Garden pea) |
Taxonomic identifieri | 3888 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › fabids › Fabales › Fabaceae › Papilionoideae › 50 kb inversion clade › NPAAA clade › Hologalegina › IRL clade › Fabeae › Pisum |
Subcellular locationi
Plasma membrane
- Cell membrane By similarity; Multi-pass membrane protein By similarity
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 57 | CytoplasmicSequence analysisAdd BLAST | 57 | |
Transmembranei | 58 – 78 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 79 – 91 | ExtracellularSequence analysisAdd BLAST | 13 | |
Transmembranei | 92 – 112 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 113 – 135 | CytoplasmicSequence analysisAdd BLAST | 23 | |
Transmembranei | 136 – 156 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 157 – 178 | ExtracellularSequence analysisAdd BLAST | 22 | |
Transmembranei | 179 – 199 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 200 – 212 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 213 – 233 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 234 – 260 | ExtracellularSequence analysisAdd BLAST | 27 | |
Transmembranei | 261 – 281 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 282 – 289 | CytoplasmicSequence analysis | 8 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000064060 | 1 – 289 | Probable aquaporin PIP-type 7aAdd BLAST | 289 |
Expressioni
Inductioni
By water stress, heat shock and to a small extent by abscisic acid (ABA). Induced within 30 min after the loss of leaf turgor.
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 39 | DisorderedSequence analysisAdd BLAST | 39 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 117 – 119 | NPA 1 | 3 | |
Motifi | 239 – 241 | NPA 2 | 3 |
Domaini
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Sequence similaritiesi
Belongs to the MIP/aquaporin (TC 1.A.8) family. PIP (TC 1.A.8.11) subfamily. [View classification]Curated
Keywords - Domaini
Repeat, Transmembrane, Transmembrane helixFamily and domain databases
CDDi | cd00333, MIP, 1 hit |
Gene3Di | 1.20.1080.10, 1 hit |
InterProi | View protein in InterPro IPR023271, Aquaporin-like IPR034294, Aquaporin_transptr IPR000425, MIP IPR022357, MIP_CS |
PANTHERi | PTHR45687, PTHR45687, 1 hit |
Pfami | View protein in Pfam PF00230, MIP, 1 hit |
PRINTSi | PR00783, MINTRINSICP |
SUPFAMi | SSF81338, SSF81338, 1 hit |
TIGRFAMsi | TIGR00861, MIP, 1 hit |
PROSITEi | View protein in PROSITE PS00221, MIP, 1 hit |
i Sequence
Sequence statusi: Complete.
P25794-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEAKEQDVSL GANKFPERQP LGIAAQSQDE PKDYQEPPPA PLFEPSELTS
60 70 80 90 100
WSFYRAGIAE FIATFLFLYI TVLTVMGVVR ESSKCKTVGI QGIAWAFGGM
110 120 130 140 150
IFALVYCTAG ISGGHINPAV TFGLFLARKL SLTRAIFYMV MQVLGAICGA
160 170 180 190 200
GVVKGFEGKQ RFGDLNGGAN FVAPGYTKGD GLGAEIVGTF ILVYTVFSAT
210 220 230 240 250
DAKRSARDSH VPILAPLPIG FAVFLVHLAT IPITGTGINP ARSLGAAIVF
260 270 280
NKKIGWNDHW IFWVGPFIGA ALAALYHQVV IRAIPFKSK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X54357 mRNA Translation: CAA38241.1 Z18288 Genomic DNA Translation: CAA79159.1 |
PIRi | S33617 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X54357 mRNA Translation: CAA38241.1 Z18288 Genomic DNA Translation: CAA79159.1 |
PIRi | S33617 |
3D structure databases
SMRi | P25794 |
ModBasei | Search... |
Protein family/group databases
TCDBi | 1.A.8.11.1, the major intrinsic protein (mip) family |
Family and domain databases
CDDi | cd00333, MIP, 1 hit |
Gene3Di | 1.20.1080.10, 1 hit |
InterProi | View protein in InterPro IPR023271, Aquaporin-like IPR034294, Aquaporin_transptr IPR000425, MIP IPR022357, MIP_CS |
PANTHERi | PTHR45687, PTHR45687, 1 hit |
Pfami | View protein in Pfam PF00230, MIP, 1 hit |
PRINTSi | PR00783, MINTRINSICP |
SUPFAMi | SSF81338, SSF81338, 1 hit |
TIGRFAMsi | TIGR00861, MIP, 1 hit |
PROSITEi | View protein in PROSITE PS00221, MIP, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | PIP2_PEA | |
Accessioni | P25794Primary (citable) accession number: P25794 Secondary accession number(s): Q41006 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1992 |
Last sequence update: | July 1, 1993 | |
Last modified: | June 2, 2021 | |
This is version 104 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |