UniProtKB - P25743 (YCHE_ECOLI)
Protein
UPF0056 membrane protein YhcE
Gene
ychE
Organism
Escherichia coli (strain K12)
Status
Functioni
Enzyme and pathway databases
BioCyci | EcoCyc:EG11342-MONOMER |
Protein family/group databases
TCDBi | 2.A.95.1.7, the 6 tms neutral amino acid transporter (naat) family |
Names & Taxonomyi
Protein namesi | Recommended name: UPF0056 membrane protein YhcE |
Gene namesi | Name:ychE Ordered Locus Names:b1242, JW1229 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane Curated; Multi-pass membrane protein Curated
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
- plasma membrane Source: EcoCyc
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 14 – 34 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 54 – 74 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 81 – 101 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 120 – 140 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 147 – 167 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 189 – 209 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000156901 | 1 – 215 | UPF0056 membrane protein YhcEAdd BLAST | 215 |
Proteomic databases
PaxDbi | P25743 |
PRIDEi | P25743 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 4263225, 10 interactors |
STRINGi | 511145.b1242 |
Family & Domainsi
Sequence similaritiesi
Belongs to the UPF0056 (MarC) family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG2095, Bacteria |
HOGENOMi | CLU_079909_2_1_6 |
InParanoidi | P25743 |
PhylomeDBi | P25743 |
Family and domain databases
InterProi | View protein in InterPro IPR002771, Multi_antbiot-R_MarC |
PANTHERi | PTHR33508, PTHR33508, 1 hit |
Pfami | View protein in Pfam PF01914, MarC, 1 hit |
TIGRFAMsi | TIGR00427, TIGR00427, 1 hit |
i Sequence
Sequence statusi: Complete.
P25743-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIQTFFDFPV YFKFFIGLFA LVNPVGIIPV FISMTSYQTA AARNKTNLTA
60 70 80 90 100
NLSVAIILWI SLFLGDTILQ LFGISIDSFR IAGGILVVTI AMSMISGKLG
110 120 130 140 150
EDKQNKQEKS ETAVRESIGV VPLALPLMAG PGAISSTIVW GTRYHSISYL
160 170 180 190 200
FGFFVAIALF ALCCWGLFRM APWLVRVLRQ TGINVITRIM GLLLMALGIE
210
FIVTGIKGIF PGLLN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X59501 Genomic DNA Translation: CAA42090.1 U00096 Genomic DNA Translation: AAC74324.1 AP009048 Genomic DNA Translation: BAA36122.2 |
PIRi | E64871 |
RefSeqi | NP_415758.1, NC_000913.3 WP_000616554.1, NZ_SSZK01000031.1 |
Genome annotation databases
EnsemblBacteriai | AAC74324; AAC74324; b1242 BAA36122; BAA36122; BAA36122 |
GeneIDi | 57732007 945836 |
KEGGi | ecj:JW1229 eco:b1242 |
PATRICi | fig|1411691.4.peg.1042 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X59501 Genomic DNA Translation: CAA42090.1 U00096 Genomic DNA Translation: AAC74324.1 AP009048 Genomic DNA Translation: BAA36122.2 |
PIRi | E64871 |
RefSeqi | NP_415758.1, NC_000913.3 WP_000616554.1, NZ_SSZK01000031.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 4263225, 10 interactors |
STRINGi | 511145.b1242 |
Protein family/group databases
TCDBi | 2.A.95.1.7, the 6 tms neutral amino acid transporter (naat) family |
Proteomic databases
PaxDbi | P25743 |
PRIDEi | P25743 |
Genome annotation databases
EnsemblBacteriai | AAC74324; AAC74324; b1242 BAA36122; BAA36122; BAA36122 |
GeneIDi | 57732007 945836 |
KEGGi | ecj:JW1229 eco:b1242 |
PATRICi | fig|1411691.4.peg.1042 |
Organism-specific databases
EchoBASEi | EB1318 |
Phylogenomic databases
eggNOGi | COG2095, Bacteria |
HOGENOMi | CLU_079909_2_1_6 |
InParanoidi | P25743 |
PhylomeDBi | P25743 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11342-MONOMER |
Miscellaneous databases
PROi | PR:P25743 |
Family and domain databases
InterProi | View protein in InterPro IPR002771, Multi_antbiot-R_MarC |
PANTHERi | PTHR33508, PTHR33508, 1 hit |
Pfami | View protein in Pfam PF01914, MarC, 1 hit |
TIGRFAMsi | TIGR00427, TIGR00427, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YCHE_ECOLI | |
Accessioni | P25743Primary (citable) accession number: P25743 Secondary accession number(s): P76025, Q9R7N0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1992 |
Last sequence update: | November 1, 1997 | |
Last modified: | February 10, 2021 | |
This is version 140 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - SIMILARITY comments
Index of protein domains and families