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Entry version 150 (31 Jul 2019)
Sequence version 2 (01 Jul 1993)
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Protein

Membrane protein insertase YidC

Gene

yidC

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Inner membrane protein required for the insertion and/or proper folding and/or complex formation of integral inner membrane proteins. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex, as well as at least 2 lipoproteins. Its own insertion requires SRP and is Sec translocase-dependent. Essential for the integration of Sec-dependent subunit a of the F0ATP synthase, FtsQ and SecE proteins and for Sec-independent subunit c of the F0ATP synthase, M13 phage procoat and the N-terminus of leader peptidase Lep. Probably interacts directly with Sec-independent substrates. Sec-dependent protein FtsQ interacts first with SecY then subsequently with YidC. Sec-dependent LacY and MalF require YidC to acquire tertiary structure and stability, a chaperone-like function, but not for membrane insertion. Stable maltose transport copmplex formation (MalFGK2) also requires YidC. Partially complements a Streptococcus mutans yidC2 disruption mutant.8 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperone
Biological processProtein transport, Translocation, Transport

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:YIDC
ECOL316407:JW3683-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.9.3.1 the membrane protein insertase (yidc/alb3/oxa1) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Membrane protein insertase YidC
Alternative name(s):
Foldase YidC
Inner membrane protein YidC
Membrane integrase YidC
Oxa1Ec
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:yidC
Ordered Locus Names:b3705, JW3683
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

Escherichia coli strain K12 genome database

More...
EcoGenei
EG11197 yidC

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 5CytoplasmicCurated5
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei6 – 23HelicalCuratedAdd BLAST18
Topological domaini24 – 342PeriplasmicAdd BLAST319
Transmembranei343 – 370HelicalCuratedAdd BLAST28
Topological domaini371 – 416CytoplasmicAdd BLAST46
Transmembranei417 – 446HelicalCuratedAdd BLAST30
Topological domaini447 – 463PeriplasmicAdd BLAST17
Transmembranei464 – 481HelicalCuratedAdd BLAST18
Topological domaini482 – 493CytoplasmicAdd BLAST12
Transmembranei494 – 509HelicalCuratedAdd BLAST16
Topological domaini510 – 512Periplasmic3
Transmembranei513 – 535HelicalCuratedAdd BLAST23
Topological domaini536 – 548CytoplasmicAdd BLAST13

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Lethality. Upon depletion experiments insertion of Sec translocase-independent integral membrane proteins ceases. Translocation of Sec-dependent protein decreases to a lesser extent. Also leads to decreased targeting and/or translocation of Lpp and BRP lipoproteins. Both spoIIIJ and yqjG of B.subtilis functionally complement yidC depletion, whereas Streptococcus mutans yidC1 and yidC2 only partially complement depletion.4 Publications

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi24 – 27EQDK → IEGR: Cold-sensitive at 30 degrees Celsius; when associated with 334-W--G-338. Protein accumulates stably. 4
Mutagenesisi334 – 338WFISQ → LEVLFQG: Cold-sensitive at 30 degrees Celsius; when associated with 24-I--R-27. Protein accumulates stably. 1 Publication5
Mutagenesisi361I → S: Loss of function. 1 Publication1
Mutagenesisi436L → S: Loss of function. 1 Publication1
Mutagenesisi483 – 487PTTVT → LVPRGS: Temperature-sensitive at 42 degrees Celsius; when associated with 512-ENLYFQG. Protein is not stable. 1 Publication5
Mutagenesisi512G → ENLYFQG: Temperature-sensitive at 42 degrees Celsius; when associated with 483-L--S-487. Protein is not stable. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001247121 – 548Membrane protein insertase YidCAdd BLAST548

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
P25714

jPOST - Japan Proteome Standard Repository/Database

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jPOSTi
P25714

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P25714

PRoteomics IDEntifications database

More...
PRIDEi
P25714

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

At mid-exponential phase in strain MC4100 there are about 2500 copies per cell (at protein level).

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with SecD and SecF.

Component of the SecDF-YajC complex, a heterotetrameric translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL) (PubMed:27435098). The stoichiometry of the super complex may be SecYEG:YidC:SecDF 4:3:1, YajC is in the reconstituted complex (with SecDF) but as no antibody is available it could not be quantified (PubMed:27435098). Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.

Found in 3 different complexes in inner membrane preparations (PubMed:16079137). Can be cross-linked to FtsH, in the larger FtsH/HflKC complex.

6 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
VIIIP036235EBI-6400779,EBI-8482910From Pseudomonas phage Pf3.

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
4261511, 290 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1095 Holo-translocon SecYEG-SecDF-YajC-YidC complex

Database of interacting proteins

More...
DIPi
DIP-12442N

Protein interaction database and analysis system

More...
IntActi
P25714, 31 interactors

Molecular INTeraction database

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MINTi
P25714

STRING: functional protein association networks

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STRINGi
511145.b3705

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1548
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P25714

Database of comparative protein structure models

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ModBasei
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

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EvolutionaryTracei
P25714

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni24 – 264Can be removed without causing lethality, dispensible for M13 procoat processingAdd BLAST241
Regioni215 – 265Interaction with SecF; not required for insertion of a number of Sec-dependent or Sec-independent substratesAdd BLAST51
Regioni265 – 346Required for Sec-dependent and Sec-independent protein insertionAdd BLAST82
Regioni527 – 548Can be removed without causing lethality, dispensible for M13 procoat processingAdd BLAST22

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Most of the large periplasmic domain (residues 24-264) is not required for either Sec-dependent or Sec-independent protein insertion. However, residues 265-346, the C-terminal part of the large periplasmic domain, are required for both Sec-dependent and Sec-independent protein insertion.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105DHW Bacteria
COG0706 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000101822

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
P25714

KEGG Orthology (KO)

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KOi
K03217

Database for complete collections of gene phylogenies

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PhylomeDBi
P25714

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
2.70.98.90, 1 hit

HAMAP database of protein families

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HAMAPi
MF_01810 YidC_type1, 1 hit

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR019998 Membr_insert_YidC
IPR028055 Membr_insert_YidC/Oxa1_C
IPR028053 Membr_insert_YidC_N
IPR001708 YidC/ALB3/OXA1/COX18
IPR038210 YidC_periplasmic
IPR038221 YidC_periplasmic_sf

The PANTHER Classification System

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PANTHERi
PTHR12428 PTHR12428, 1 hit

Pfam protein domain database

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Pfami
View protein in Pfam
PF02096 60KD_IMP, 1 hit
PF14849 YidC_periplas, 1 hit

Protein Motif fingerprint database; a protein domain database

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PRINTSi
PR00701 60KDINNERMP
PR01900 YIDCPROTEIN

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03593 yidC_nterm, 1 hit
TIGR03592 yidC_oxa1_cterm, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P25714-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDSQRNLLVI ALLFVSFMIW QAWEQDKNPQ PQAQQTTQTT TTAAGSAADQ
60 70 80 90 100
GVPASGQGKL ISVKTDVLDL TINTRGGDVE QALLPAYPKE LNSTQPFQLL
110 120 130 140 150
ETSPQFIYQA QSGLTGRDGP DNPANGPRPL YNVEKDAYVL AEGQNELQVP
160 170 180 190 200
MTYTDAAGNT FTKTFVLKRG DYAVNVNYNV QNAGEKPLEI SSFGQLKQSI
210 220 230 240 250
TLPPHLDTGS SNFALHTFRG AAYSTPDEKY EKYKFDTIAD NENLNISSKG
260 270 280 290 300
GWVAMLQQYF ATAWIPHNDG TNNFYTANLG NGIAAIGYKS QPVLVQPGQT
310 320 330 340 350
GAMNSTLWVG PEIQDKMAAV APHLDLTVDY GWLWFISQPL FKLLKWIHSF
360 370 380 390 400
VGNWGFSIII ITFIVRGIMY PLTKAQYTSM AKMRMLQPKI QAMRERLGDD
410 420 430 440 450
KQRISQEMMA LYKAEKVNPL GGCFPLLIQM PIFLALYYML MGSVELRQAP
460 470 480 490 500
FALWIHDLSA QDPYYILPIL MGVTMFFIQK MSPTTVTDPM QQKIMTFMPV
510 520 530 540
IFTVFFLWFP SGLVLYYIVS NLVTIIQQQL IYRGLEKRGL HSREKKKS
Length:548
Mass (Da):61,526
Last modified:July 1, 1993 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i95EBC5DAB4F2FCFB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
L10328 Genomic DNA Translation: AAA62056.1
U00096 Genomic DNA Translation: AAC76728.1
AP009048 Genomic DNA Translation: BAE77588.1
M11056 Genomic DNA No translation available.

Protein sequence database of the Protein Information Resource

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PIRi
B65173

NCBI Reference Sequences

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RefSeqi
NP_418161.1, NC_000913.3
WP_000378250.1, NZ_SSZK01000035.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

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EnsemblBacteriai
AAC76728; AAC76728; b3705
BAE77588; BAE77588; BAE77588

Database of genes from NCBI RefSeq genomes

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GeneIDi
948214

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ecj:JW3683
eco:b3705

Pathosystems Resource Integration Center (PATRIC)

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PATRICi
fig|1411691.4.peg.2998

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10328 Genomic DNA Translation: AAA62056.1
U00096 Genomic DNA Translation: AAC76728.1
AP009048 Genomic DNA Translation: BAE77588.1
M11056 Genomic DNA No translation available.
PIRiB65173
RefSeqiNP_418161.1, NC_000913.3
WP_000378250.1, NZ_SSZK01000035.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

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RCSB PDBi

Protein Data Bank Japan

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PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3BLCX-ray2.50A/B26-340[»]
3BS6X-ray1.80A/B56-329[»]
4UTQelectron microscopy8.00A1-548[»]
5M5Helectron microscopy4.50A1-540[»]
5MG3electron microscopy14.00C2-548[»]
6AL2X-ray2.80A/B1-540[»]
SMRiP25714
ModBaseiSearch...

Protein-protein interaction databases

BioGridi4261511, 290 interactors
ComplexPortaliCPX-1095 Holo-translocon SecYEG-SecDF-YajC-YidC complex
DIPiDIP-12442N
IntActiP25714, 31 interactors
MINTiP25714
STRINGi511145.b3705

Protein family/group databases

TCDBi2.A.9.3.1 the membrane protein insertase (yidc/alb3/oxa1) family

Proteomic databases

EPDiP25714
jPOSTiP25714
PaxDbiP25714
PRIDEiP25714

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
948214
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76728; AAC76728; b3705
BAE77588; BAE77588; BAE77588
GeneIDi948214
KEGGiecj:JW3683
eco:b3705
PATRICifig|1411691.4.peg.2998

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB1183
EcoGeneiEG11197 yidC

Phylogenomic databases

eggNOGiENOG4105DHW Bacteria
COG0706 LUCA
HOGENOMiHOG000101822
InParanoidiP25714
KOiK03217
PhylomeDBiP25714

Enzyme and pathway databases

BioCyciEcoCyc:YIDC
ECOL316407:JW3683-MONOMER

Miscellaneous databases

EvolutionaryTraceiP25714

Protein Ontology

More...
PROi
PR:P25714

Family and domain databases

Gene3Di2.70.98.90, 1 hit
HAMAPiMF_01810 YidC_type1, 1 hit
InterProiView protein in InterPro
IPR019998 Membr_insert_YidC
IPR028055 Membr_insert_YidC/Oxa1_C
IPR028053 Membr_insert_YidC_N
IPR001708 YidC/ALB3/OXA1/COX18
IPR038210 YidC_periplasmic
IPR038221 YidC_periplasmic_sf
PANTHERiPTHR12428 PTHR12428, 1 hit
PfamiView protein in Pfam
PF02096 60KD_IMP, 1 hit
PF14849 YidC_periplas, 1 hit
PRINTSiPR00701 60KDINNERMP
PR01900 YIDCPROTEIN
TIGRFAMsiTIGR03593 yidC_nterm, 1 hit
TIGR03592 yidC_oxa1_cterm, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiYIDC_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P25714
Secondary accession number(s): Q2M818
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: July 1, 1993
Last modified: July 31, 2019
This is version 150 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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