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Entry version 194 (02 Jun 2021)
Sequence version 3 (05 Oct 2010)
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Protein

General negative regulator of transcription subunit 1

Gene

CDC39

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. The NOT protein subcomplex negatively regulates the basal and activated transcription of many genes. Preferentially affects TC-type TATA element-dependent transcription. Could directly or indirectly inhibit component(s) of the general transcription machinery.

1 Publication

Miscellaneous

Present with 4300 molecules/cell in log phase SD medium.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Repressor
Biological processTranscription, Transcription regulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
General negative regulator of transcription subunit 1
Alternative name(s):
Cell division cycle protein 39
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDC39
Synonyms:NOT1, ROS1
Ordered Locus Names:YCR093W
ORF Names:YCR1151, YCR93W
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri559292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002311 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

Saccharomyces Genome Database

More...
SGDi
S000000689, CDC39

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:YCR093W

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000969551 – 2108General negative regulator of transcription subunit 1Add BLAST2108

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2102PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P25655

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P25655

PRoteomics IDEntifications database

More...
PRIDEi
P25655

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P25655

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Forms a NOT protein complex that comprises NOT1, NOT2, NOT3, NOT4 and NOT5. Subunit of the 1.0 MDa CCR4-NOT core complex that contains CCR4, CAF1, NOT1, NOT2, NOT3, NOT4, NOT5, CAF40 and CAF130. In the complex interacts with CCR4, POP2, NOT2, NOT4 and NOT5. The core complex probably is part of a less characterized 1.9 MDa CCR4-NOT complex.

3 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Hide details

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
31065, 357 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-1800, CCR4-NOT mRNA deadenylase complex

Database of interacting proteins

More...
DIPi
DIP-1202N

Protein interaction database and analysis system

More...
IntActi
P25655, 44 interactors

Molecular INTeraction database

More...
MINTi
P25655

STRING: functional protein association networks

More...
STRINGi
4932.YCR093W

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P25655, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

12108
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P25655

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1323 – 1352DisorderedSequence analysisAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili795 – 813Sequence analysisAdd BLAST19
Coiled coili1021 – 1046Sequence analysisAdd BLAST26

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CNOT1 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1831, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014869

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000286_3_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P25655

Identification of Orthologs from Complete Genome Data

More...
OMAi
WESCNQP

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.180, 1 hit
1.25.40.840, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007196, CCR4-Not_Not1_C
IPR024557, CCR4-Not_Not1su_DUF3819
IPR040398, CNOT1
IPR032191, CNOT1_CAF1_bind
IPR032194, CNOT1_HEAT
IPR032195, CNOT1_HEAT_N
IPR032193, CNOT1_TTP_bind
IPR038535, CNOT1_TTP_bind_sf
IPR016021, MIF4-like_sf

The PANTHER Classification System

More...
PANTHERi
PTHR13162, PTHR13162, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16415, CNOT1_CAF1_bind, 1 hit
PF16418, CNOT1_HEAT, 1 hit
PF16419, CNOT1_HEAT_N, 1 hit
PF16417, CNOT1_TTP_bind, 1 hit
PF12842, DUF3819, 1 hit
PF04054, Not1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P25655-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLSATYRDLN TASNLETSKE KQAAQIVIAQ ISLLFTTLNN DNFESVEREI
60 70 80 90 100
RHILDRSSVD IYIKVWERLL TLSSRDILQA GKFLLQENLL HRLLLEFAKD
110 120 130 140 150
LPKKSTDLIE LLKERTFNNQ EFQKQTGITL SLFIDLFDKS ANKDIIESLD
160 170 180 190 200
RSSQINDFKT IKMNHTNYLR NFFLQTTPET LESNLRDLLH SLEGESLNDL
210 220 230 240 250
LALLLSEILS PGSQNLQNDP TRSWLTPPMV LDATNRGNVI ARSISSLQAN
260 270 280 290 300
QINWNRVFNL MSTKYFLSAP LMPTTASLSC LFAALHDGPV IDEFFSCDWK
310 320 330 340 350
VIFKLDLAIQ LHKWSVQNGC FDLLNAEGTR KVSETIPNTK QSLLYLLSIA
360 370 380 390 400
SLNLELFLQR EELSDGPMLA YFQECFFEDF NYAPEYLILA LVKEMKRFVL
410 420 430 440 450
LIENRTVIDE ILITLLIQVH NKSPSSFKDV ISTITDDSKI VDAAKIIINS
460 470 480 490 500
DDAPIANFLK SLLDTGRLDT VINKLPFNEA FKILPCARQI GWEGFDTFLK
510 520 530 540 550
TKVSPSNVDV VLESLEVQTK MTDTNTPFRS LKTFDLFAFH SLIEVLNKCP
560 570 580 590 600
LDVLQLQRFE SLEFSLLIAF PRLINFGFGH DEAILANGDI AGINNDIEKE
610 620 630 640 650
MQNYLQKMYS GELAIKDVIE LLRRLRDSDL PRDQEVFTCI THAVIAESTF
660 670 680 690 700
FQDYPLDALA TTSVLFGSMI LFQLLRGFVL DVAFRIIMRF AKEPPESKMF
710 720 730 740 750
KFAVQAIYAF RIRLAEYPQY CKDLLRDVPA LKSQAQVYQS IVEAATLANA
760 770 780 790 800
PKERSRPVQE MIPLKFFAVD EVSCQINQEG APKDVVEKVL FVLNNVTLAN
810 820 830 840 850
LNNKVDELKK SLTPNYFSWF STYLVTQRAK TEPNYHDLYS KVIVAMGSGL
860 870 880 890 900
LHQFMVNVTL RQLFVLLSTK DEQAIDKKHL KNLASWLGCI TLALNKPIKH
910 920 930 940 950
KNIAFREMLI EAYKENRLEI VVPFVTKILQ RASESKIFKP PNPWTVGILK
960 970 980 990 1000
LLIELNEKAN WKLSLTFEVE VLLKSFNLTT KSLKPSNFIN TPEVIETLSG
1010 1020 1030 1040 1050
ALGSITLEQQ QTEQQRQIIL MQQHQQQMLI YQQRQQQQQQ RQQQQQHHIS
1060 1070 1080 1090 1100
ANTIADQQAA FGGEGSISHD NPFNNLLGST IFVTHPDLKR VFQMALAKSV
1110 1120 1130 1140 1150
REILLEVVEK SSGIAVVTTT KIILKDFATE VDESKLKTAA IIMVRHLAQS
1160 1170 1180 1190 1200
LARATSIEPL KEGIRSTMQS LAPNLMSLSS SPAEELDTAI NENIGIALVL
1210 1220 1230 1240 1250
IEKASMDKST QDLADQLMQA IAIRRYHKER RADQPFITQN TNPYSLSLPE
1260 1270 1280 1290 1300
PLGLKNTGVT PQQFRVYEEF GKNIPNLDVI PFAGLPAHAP PMTQNVGLTQ
1310 1320 1330 1340 1350
PQQQQAQMPT QILTSEQIRA QQQQQQLQKS RLNQPSQSAQ PPGVNVPNPQ
1360 1370 1380 1390 1400
GGIAAVQSDL EQNQRVLVHL MDILVSQIKE NATKNNLAEL GDQNQIKTII
1410 1420 1430 1440 1450
FQILTFIAKS AQKDQLALKV SQAVVNSLFA TSESPLCREV LSLLLEKLCS
1460 1470 1480 1490 1500
LSLVARKDVV WWLVYALDSR KFNVPVIRSL LEVNLIDATE LDNVLVTAMK
1510 1520 1530 1540 1550
NKMENSTEFA MKLIQNTVLS DDPILMRMDF IKTLEHLASS EDENVKKFIK
1560 1570 1580 1590 1600
EFEDTKIMPV RKGTKTTRTE KLYLVFTEWV KLLQRVENND VITTVFIKQL
1610 1620 1630 1640 1650
VEKGVISDTD NLLTFVKSSL ELSVSSFKES DPTDEVFIAI DALGSLIIKL
1660 1670 1680 1690 1700
LILQGFKDDT RRDYINAIFS VIVLVFAKDH SQEGTTFNER PYFRLFSNIL
1710 1720 1730 1740 1750
YEWATIRTHN FVRISDSSTR QELIEFDSVF YNTFSGYLHA LQPFAFPGFS
1760 1770 1780 1790 1800
FAWVTLLSHR MLLPIMLRLP NKIGWEKLML LIIDLFKFLD QYTSKHAVSD
1810 1820 1830 1840 1850
AVSVVYKGTL RVILGISNDM PSFLIENHYE LMNNLPPTYF QLKNVILSAI
1860 1870 1880 1890 1900
PKNMTVPNPY DVDLNMEDIP ACKELPEVFF DPVIDLHSLK KPVDNYLRIP
1910 1920 1930 1940 1950
SNSLLRTILS AIYKDTYDIK KGVGYDFLSV DSKLIRAIVL HVGIEAGIEY
1960 1970 1980 1990 2000
KRTSSNAVFN TKSSYYTLLF NLIQNGSIEM KYQIILSIVE QLRYPNIHTY
2010 2020 2030 2040 2050
WFSFVLMNMF KSDEWNDQKL EVQEIILRNF LKRIIVNKPH TWGVSVFFTQ
2060 2070 2080 2090 2100
LINNNDINLL DLPFVQSVPE IKLILQQLVK YSKKYTTSEQ DDQSATINRR

QTPLQSNA
Length:2,108
Mass (Da):240,279
Last modified:October 5, 2010 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5B2AE15BCF95E009
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti526T → A in CAA49721 (PubMed:8428577).Curated1
Sequence conflicti569A → R in CAA49721 (PubMed:8428577).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X70151 Genomic DNA Translation: CAA49721.1
X59720 Genomic DNA Translation: CAA42248.2
BK006937 Genomic DNA Translation: DAA07562.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S28417

NCBI Reference Sequences

More...
RefSeqi
NP_010017.2, NM_001178799.1

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
YCR093W_mRNA; YCR093W; YCR093W

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
850455

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
sce:YCR093W

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X70151 Genomic DNA Translation: CAA49721.1
X59720 Genomic DNA Translation: CAA42248.2
BK006937 Genomic DNA Translation: DAA07562.1
PIRiS28417
RefSeqiNP_010017.2, NM_001178799.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4B89X-ray1.50A755-1000[»]
4B8AX-ray2.40A755-1000[»]
4B8BX-ray2.80A/B151-753[»]
4B8CX-ray3.41B/G/H/I755-1000[»]
4BY6X-ray2.80A/D1541-2093[»]
4CV5X-ray3.81A/C1071-1282[»]
5AJDX-ray3.62A/C/E/G/I/K1541-2093[»]
SMRiP25655
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi31065, 357 interactors
ComplexPortaliCPX-1800, CCR4-NOT mRNA deadenylase complex
DIPiDIP-1202N
IntActiP25655, 44 interactors
MINTiP25655
STRINGi4932.YCR093W

PTM databases

iPTMnetiP25655

Proteomic databases

MaxQBiP25655
PaxDbiP25655
PRIDEiP25655

Genome annotation databases

EnsemblFungiiYCR093W_mRNA; YCR093W; YCR093W
GeneIDi850455
KEGGisce:YCR093W

Organism-specific databases

SGDiS000000689, CDC39
VEuPathDBiFungiDB:YCR093W

Phylogenomic databases

eggNOGiKOG1831, Eukaryota
GeneTreeiENSGT00390000014869
HOGENOMiCLU_000286_3_1_1
InParanoidiP25655
OMAiWESCNQP

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P25655
RNActiP25655, protein

Family and domain databases

Gene3Di1.25.40.180, 1 hit
1.25.40.840, 1 hit
InterProiView protein in InterPro
IPR007196, CCR4-Not_Not1_C
IPR024557, CCR4-Not_Not1su_DUF3819
IPR040398, CNOT1
IPR032191, CNOT1_CAF1_bind
IPR032194, CNOT1_HEAT
IPR032195, CNOT1_HEAT_N
IPR032193, CNOT1_TTP_bind
IPR038535, CNOT1_TTP_bind_sf
IPR016021, MIF4-like_sf
PANTHERiPTHR13162, PTHR13162, 1 hit
PfamiView protein in Pfam
PF16415, CNOT1_CAF1_bind, 1 hit
PF16418, CNOT1_HEAT, 1 hit
PF16419, CNOT1_HEAT_N, 1 hit
PF16417, CNOT1_TTP_bind, 1 hit
PF12842, DUF3819, 1 hit
PF04054, Not1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNOT1_YEAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P25655
Secondary accession number(s): D6VR93
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: October 5, 2010
Last modified: June 2, 2021
This is version 194 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  4. SIMILARITY comments
    Index of protein domains and families
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