UniProtKB - P25531 (YICR_ECOLI)
Protein
UPF0758 protein YicR
Gene
yicR
Organism
Escherichia coli (strain K12)
Status
Functioni
Caution
Was originally thought to be the site of the radC102 mutation, but it was subsequently shown that radC102 is an allele of RecG.1 Publication
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 171 | Zinc; catalyticPROSITE-ProRule annotation | 1 | |
Metal bindingi | 173 | Zinc; catalyticPROSITE-ProRule annotation | 1 | |
Metal bindingi | 184 | Zinc; catalyticPROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- metallopeptidase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Hydrolase, Metalloprotease, Protease |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11312-MONOMER ECOL316407:JW5643-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: UPF0758 protein YicR |
Gene namesi | Name:yicR Ordered Locus Names:b3638, JW5643 |
Organismi | Escherichia coli (strain K12) |
Taxonomic identifieri | 83333 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000190694 | 1 – 222 | UPF0758 protein YicRAdd BLAST | 222 |
Proteomic databases
PaxDbi | P25531 |
PRIDEi | P25531 |
Interactioni
Protein-protein interaction databases
BioGridi | 4261656, 200 interactors |
DIPi | DIP-10636N |
IntActi | P25531, 2 interactors |
STRINGi | 511145.b3638 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 100 – 222 | MPNPROSITE-ProRule annotationAdd BLAST | 123 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 171 – 184 | JAMM motifPROSITE-ProRule annotationAdd BLAST | 14 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG4105W5Q Bacteria COG2003 LUCA |
HOGENOMi | HOG000273376 |
InParanoidi | P25531 |
KOi | K03630 |
PhylomeDBi | P25531 |
Family and domain databases
CDDi | cd08071 MPN_DUF2466, 1 hit |
HAMAPi | MF_00018 UPF0758_YicR, 1 hit |
InterProi | View protein in InterPro IPR037518 MPN IPR025657 RadC_JAB IPR010994 RuvA_2-like IPR001405 UPF0758 IPR020891 UPF0758_CS IPR022820 UPF0758_YicR |
PANTHERi | PTHR30471 PTHR30471, 1 hit |
Pfami | View protein in Pfam PF04002 RadC, 1 hit |
SUPFAMi | SSF47781 SSF47781, 1 hit |
TIGRFAMsi | TIGR00608 radc, 1 hit |
PROSITEi | View protein in PROSITE PS50249 MPN, 1 hit PS01302 UPF0758, 1 hit |
i Sequence
Sequence statusi: Complete.
P25531-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKNNSQLLMP REKMLKFGIS ALTDVELLAL FLRTGTRGKD VLTLAKEMLE
60 70 80 90 100
NFGSLYGLLT SEYEQFSGVH GIGVAKFAQL KGIAELARRY YNVRMREESP
110 120 130 140 150
LLSPEMTREF LQSQLTGEER EIFMVIFLDS QHRVITHRRL FSGTLNHVEV
160 170 180 190 200
HPREIIREAI KINASALILA HNHPSGCAEP SKADKLITER IIKSCQFMDL
210 220
RVLDHIVIGR GEYVSFAERG WI
Sequence cautioni
The sequence AAA61991 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA61991.1 Different initiation. U00096 Genomic DNA Translation: AAC76662.2 AP009048 Genomic DNA Translation: BAE77654.1 X63366 Genomic DNA Translation: CAA44966.1 X63367 Genomic DNA Translation: CAA44967.1 |
PIRi | H65164 |
RefSeqi | NP_418095.4, NC_000913.3 WP_001350561.1, NZ_LN832404.1 |
Genome annotation databases
EnsemblBacteriai | AAC76662; AAC76662; b3638 BAE77654; BAE77654; BAE77654 |
GeneIDi | 948968 |
KEGGi | ecj:JW5643 eco:b3638 |
PATRICi | fig|511145.12.peg.3758 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L10328 Genomic DNA Translation: AAA61991.1 Different initiation. U00096 Genomic DNA Translation: AAC76662.2 AP009048 Genomic DNA Translation: BAE77654.1 X63366 Genomic DNA Translation: CAA44966.1 X63367 Genomic DNA Translation: CAA44967.1 |
PIRi | H65164 |
RefSeqi | NP_418095.4, NC_000913.3 WP_001350561.1, NZ_LN832404.1 |
3D structure databases
SMRi | P25531 |
ModBasei | Search... |
Protein-protein interaction databases
BioGridi | 4261656, 200 interactors |
DIPi | DIP-10636N |
IntActi | P25531, 2 interactors |
STRINGi | 511145.b3638 |
Proteomic databases
PaxDbi | P25531 |
PRIDEi | P25531 |
Genome annotation databases
EnsemblBacteriai | AAC76662; AAC76662; b3638 BAE77654; BAE77654; BAE77654 |
GeneIDi | 948968 |
KEGGi | ecj:JW5643 eco:b3638 |
PATRICi | fig|511145.12.peg.3758 |
Organism-specific databases
EchoBASEi | EB1288 |
Phylogenomic databases
eggNOGi | ENOG4105W5Q Bacteria COG2003 LUCA |
HOGENOMi | HOG000273376 |
InParanoidi | P25531 |
KOi | K03630 |
PhylomeDBi | P25531 |
Enzyme and pathway databases
BioCyci | EcoCyc:EG11312-MONOMER ECOL316407:JW5643-MONOMER |
Miscellaneous databases
PROi | PR:P25531 |
Family and domain databases
CDDi | cd08071 MPN_DUF2466, 1 hit |
HAMAPi | MF_00018 UPF0758_YicR, 1 hit |
InterProi | View protein in InterPro IPR037518 MPN IPR025657 RadC_JAB IPR010994 RuvA_2-like IPR001405 UPF0758 IPR020891 UPF0758_CS IPR022820 UPF0758_YicR |
PANTHERi | PTHR30471 PTHR30471, 1 hit |
Pfami | View protein in Pfam PF04002 RadC, 1 hit |
SUPFAMi | SSF47781 SSF47781, 1 hit |
TIGRFAMsi | TIGR00608 radc, 1 hit |
PROSITEi | View protein in PROSITE PS50249 MPN, 1 hit PS01302 UPF0758, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | YICR_ECOLI | |
Accessioni | P25531Primary (citable) accession number: P25531 Secondary accession number(s): Q2M7V2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1992 |
Last sequence update: | May 30, 2000 | |
Last modified: | November 13, 2019 | |
This is version 148 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- Uncharacterized protein families (UPF)
List of uncharacterized protein family (UPF) entries - SIMILARITY comments
Index of protein domains and families - Escherichia coli
Escherichia coli (strain K12): entries and cross-references to EcoGene