UniProtKB - P25490 (TYY1_HUMAN)
Transcriptional repressor protein YY1
YY1
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 298 | Zinc 1 | 1 | |
Metal bindingi | 303 | Zinc 1 | 1 | |
Metal bindingi | 316 | Zinc 1 | 1 | |
Metal bindingi | 320 | Zinc 1 | 1 | |
Metal bindingi | 327 | Zinc 2 | 1 | |
Metal bindingi | 330 | Zinc 2 | 1 | |
Metal bindingi | 343 | Zinc 2 | 1 | |
Metal bindingi | 347 | Zinc 2 | 1 | |
Metal bindingi | 355 | Zinc 3 | 1 | |
Metal bindingi | 360 | Zinc 3 | 1 | |
Metal bindingi | 373 | Zinc 3 | 1 | |
Metal bindingi | 377 | Zinc 3 | 1 | |
Metal bindingi | 385 | Zinc 4 | 1 | |
Metal bindingi | 390 | Zinc 4 | 1 | |
Metal bindingi | 403 | Zinc 4 | 1 | |
Metal bindingi | 407 | Zinc 4 | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 296 – 320 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 325 – 347 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 353 – 377 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 383 – 407 | C2H2-type 4PROSITE-ProRule annotationAdd BLAST | 25 |
GO - Molecular functioni
- cis-regulatory region sequence-specific DNA binding Source: UniProtKB
- DNA binding Source: MGI
- DNA-binding transcription repressor activity Source: GO_Central
- DNA-binding transcription repressor activity, RNA polymerase II-specific Source: GO_Central
- four-way junction DNA binding Source: UniProtKB
- metal ion binding Source: UniProtKB-KW
- RNA binding Source: MGI
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: GO_Central
- sequence-specific double-stranded DNA binding Source: ARUK-UCL
- SMAD binding Source: AgBase
- transcription regulatory region sequence-specific DNA binding Source: MGI
GO - Biological processi
- anterior/posterior pattern specification Source: Ensembl
- camera-type eye morphogenesis Source: Ensembl
- cell differentiation Source: UniProtKB-KW
- cellular response to DNA damage stimulus Source: UniProtKB
- cellular response to interleukin-1 Source: Ensembl
- cellular response to UV Source: UniProtKB
- chromosome organization Source: Ensembl
- double-strand break repair via homologous recombination Source: UniProtKB
- negative regulation of cell growth involved in cardiac muscle cell development Source: Ensembl
- negative regulation of gene expression Source: CACAO
- negative regulation of interferon-beta production Source: UniProtKB
- negative regulation of pri-miRNA transcription by RNA polymerase II Source: Ensembl
- negative regulation of transcription by RNA polymerase II Source: UniProtKB
- positive regulation of transcription by RNA polymerase II Source: Ensembl
- protein deubiquitination Source: Reactome
- regulation of transcription by RNA polymerase II Source: Reactome
- response to prostaglandin F Source: Ensembl
- response to UV-C Source: UniProtKB
- RNA localization Source: Ensembl
- spermatogenesis Source: UniProtKB-KW
Keywordsi
Molecular function | Activator, DNA-binding, Repressor |
Biological process | Differentiation, DNA damage, DNA recombination, DNA repair, Spermatogenesis, Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
PathwayCommonsi | P25490 |
Reactomei | R-HSA-5617472, Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5689603, UCH proteinases R-HSA-5696394, DNA Damage Recognition in GG-NER R-HSA-8866910, TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-9018519, Estrogen-dependent gene expression |
SignaLinki | P25490 |
SIGNORi | P25490 |
Names & Taxonomyi
Protein namesi | Recommended name: Transcriptional repressor protein YY1Alternative name(s): Delta transcription factor INO80 complex subunit S NF-E1 Yin and yang 1 Short name: YY-1 |
Gene namesi | Name:YY1 Synonyms:INO80S |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000100811.10 |
HGNCi | HGNC:12856, YY1 |
MIMi | 600013, gene |
neXtProti | NX_P25490 |
Subcellular locationi
Nucleus
- Nucleus matrix 3 Publications
Note: Associated with the nuclear matrix.
Nucleus
- Ino80 complex Source: UniProtKB
- nuclear chromatin Source: GO_Central
- nuclear matrix Source: UniProtKB-SubCell
- nucleoplasm Source: Reactome
- nucleus Source: UniProtKB
- PcG protein complex Source: GO_Central
Other locations
- cytoplasm Source: Ensembl
- transcription regulator complex Source: GO_Central
Keywords - Cellular componenti
NucleusPathology & Biotechi
Involvement in diseasei
Gabriele-de Vries syndrome (GADEVS)2 Publications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_079202 | 179 – 414 | Missing in GADEVS. 1 PublicationAdd BLAST | 236 | |
Natural variantiVAR_079203 | 320 | H → Y in GADEVS; unknown pathological significance. 1 Publication | 1 | |
Natural variantiVAR_079204 | 339 | K → Q in GADEVS; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1555370868EnsemblClinVar. | 1 | |
Natural variantiVAR_079205 | 344 – 414 | Missing in GADEVS. 1 PublicationAdd BLAST | 71 | |
Natural variantiVAR_079206 | 366 | L → P in GADEVS; reduced DNA-binding; reduced transcription regulator activity. 1 PublicationCorresponds to variant dbSNP:rs1131692163EnsemblClinVar. | 1 | |
Natural variantiVAR_079207 | 366 | L → V in GADEVS; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1131692044EnsemblClinVar. | 1 | |
Natural variantiVAR_065086 | 380 | D → Y in GADEVS; reduced DNA-binding; reduced transcription regulator activity. 2 PublicationsCorresponds to variant dbSNP:rs1131692043EnsemblClinVar. | 1 | |
Natural variantiVAR_079208 | 393 | Missing in GADEVS; unknown pathological significance. 1 Publication | 1 |
Keywords - Diseasei
Disease mutation, Mental retardationOrganism-specific databases
DisGeNETi | 7528 |
MalaCardsi | YY1 |
MIMi | 617557, phenotype |
OpenTargetsi | ENSG00000100811 |
Orphaneti | 506358, Gabriele-de Vries syndrome |
PharmGKBi | PA37445 |
Miscellaneous databases
Pharosi | P25490, Tbio |
Polymorphism and mutation databases
BioMutai | YY1 |
DMDMi | 3915889 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000047190 | 1 – 414 | Transcriptional repressor protein YY1Add BLAST | 414 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 118 | PhosphoserineCombined sources | 1 | |
Cross-linki | 182 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Cross-linki | 183 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 187 | PhosphoserineCombined sources | 1 | |
Cross-linki | 208 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Cross-linki | 230 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 247 | PhosphoserineCombined sources | 1 | |
Cross-linki | 286 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Cross-linki | 288 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 378 | PhosphothreonineCombined sources | 1 | |
Cross-linki | 409 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Cross-linki | 411 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources |
Post-translational modificationi
Keywords - PTMi
ADP-ribosylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | P25490 |
jPOSTi | P25490 |
MassIVEi | P25490 |
MaxQBi | P25490 |
PaxDbi | P25490 |
PeptideAtlasi | P25490 |
PRIDEi | P25490 |
ProteomicsDBi | 54279 |
PTM databases
iPTMneti | P25490 |
PhosphoSitePlusi | P25490 |
Expressioni
Gene expression databases
Bgeei | ENSG00000100811, Expressed in amniotic fluid and 252 other tissues |
ExpressionAtlasi | P25490, baseline and differential |
Genevisiblei | P25490, HS |
Organism-specific databases
HPAi | ENSG00000100811, Low tissue specificity |
Interactioni
Subunit structurei
Interacts with YAF2 through the region encompassing the first and second zinc fingers (PubMed:9016636).
Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80 (PubMed:17721549, PubMed:18026119, PubMed:18922472, PubMed:21303910).
Interacts with EED and EZH2; the interactions are indicative for an association with the PRC2/EED-EZH2 complex (PubMed:11158321).
Interacts with SFMBT2 (PubMed:23385818).
Found in a complex with SMAD1 and SMAD4 (PubMed:15329343).
Found in a complex with YY1, SIN3A and HDAC1 (By similarity).
By similarity8 PublicationsBinary interactionsi
Hide detailsP25490
GO - Molecular functioni
- SMAD binding Source: AgBase
Protein-protein interaction databases
BioGRIDi | 113360, 176 interactors |
ComplexPortali | CPX-846, INO80 chromatin remodeling complex |
CORUMi | P25490 |
DIPi | DIP-150N |
IntActi | P25490, 108 interactors |
MINTi | P25490 |
STRINGi | 9606.ENSP00000262238 |
Miscellaneous databases
RNActi | P25490, protein |
Structurei
Secondary structure
3D structure databases
SMRi | P25490 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P25490 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 170 | Interaction with the SMAD1/SMAD4 complexAdd BLAST | 170 | |
Regioni | 257 – 341 | Involved in nuclear matrix associationAdd BLAST | 85 | |
Regioni | 295 – 414 | Binding to DNAAdd BLAST | 120 | |
Regioni | 333 – 371 | Involved in repression of activated transcriptionAdd BLAST | 39 | |
Regioni | 371 – 397 | Involved in masking transactivation domainAdd BLAST | 27 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 43 – 53 | Asp/Glu-rich (acidic)Add BLAST | 11 | |
Compositional biasi | 54 – 69 | Gly-richAdd BLAST | 16 | |
Compositional biasi | 70 – 80 | Poly-HisAdd BLAST | 11 | |
Compositional biasi | 159 – 170 | Gly/Ser-richAdd BLAST | 12 |
Sequence similaritiesi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 296 – 320 | C2H2-type 1PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 325 – 347 | C2H2-type 2PROSITE-ProRule annotationAdd BLAST | 23 | |
Zinc fingeri | 353 – 377 | C2H2-type 3PROSITE-ProRule annotationAdd BLAST | 25 | |
Zinc fingeri | 383 – 407 | C2H2-type 4PROSITE-ProRule annotationAdd BLAST | 25 |
Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000154763 |
InParanoidi | P25490 |
OMAi | MWASDDN |
OrthoDBi | 1318335at2759 |
PhylomeDBi | P25490 |
TreeFami | TF106493 |
Family and domain databases
IDEALi | IID00234 |
InterProi | View protein in InterPro IPR017114, YY1-like IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
PIRSFi | PIRSF037113, TF_Yin_yang, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 4 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 4 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
10 20 30 40 50
MASGDTLYIA TDGSEMPAEI VELHEIEVET IPVETIETTV VGEEEEEDDD
60 70 80 90 100
DEDGGGGDHG GGGGHGHAGH HHHHHHHHHH PPMIALQPLV TDDPTQVHHH
110 120 130 140 150
QEVILVQTRE EVVGGDDSDG LRAEDGFEDQ ILIPVPAPAG GDDDYIEQTL
160 170 180 190 200
VTVAAAGKSG GGGSSSSGGG RVKKGGGKKS GKKSYLSGGA GAAGGGGADP
210 220 230 240 250
GNKKWEQKQV QIKTLEGEFS VTMWSSDEKK DIDHETVVEE QIIGENSPPD
260 270 280 290 300
YSEYMTGKKL PPGGIPGIDL SDPKQLAEFA RMKPRKIKED DAPRTIACPH
310 320 330 340 350
KGCTKMFRDN SAMRKHLHTH GPRVHVCAEC GKAFVESSKL KRHQLVHTGE
360 370 380 390 400
KPFQCTFEGC GKRFSLDFNL RTHVRIHTGD RPYVCPFDGC NKKFAQSTNL
410
KSHILTHAKA KNNQ
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketH0YJV7 | H0YJV7_HUMAN | Transcriptional repressor protein Y... | YY1 | 190 | Annotation score: | ||
H0YJU4 | H0YJU4_HUMAN | Transcriptional repressor protein Y... | YY1 | 123 | Annotation score: | ||
A0A494C032 | A0A494C032_HUMAN | Transcriptional repressor protein Y... | YY1 | 117 | Annotation score: | ||
G3V3M8 | G3V3M8_HUMAN | Transcriptional repressor protein Y... | YY1 | 34 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 65 | H → R in AAA59926 (PubMed:1946405).Curated | 1 | |
Sequence conflicti | 196 | G → R in AAA59467 (PubMed:1655281).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_079202 | 179 – 414 | Missing in GADEVS. 1 PublicationAdd BLAST | 236 | |
Natural variantiVAR_079203 | 320 | H → Y in GADEVS; unknown pathological significance. 1 Publication | 1 | |
Natural variantiVAR_079204 | 339 | K → Q in GADEVS; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1555370868EnsemblClinVar. | 1 | |
Natural variantiVAR_079205 | 344 – 414 | Missing in GADEVS. 1 PublicationAdd BLAST | 71 | |
Natural variantiVAR_079206 | 366 | L → P in GADEVS; reduced DNA-binding; reduced transcription regulator activity. 1 PublicationCorresponds to variant dbSNP:rs1131692163EnsemblClinVar. | 1 | |
Natural variantiVAR_079207 | 366 | L → V in GADEVS; unknown pathological significance. 1 PublicationCorresponds to variant dbSNP:rs1131692044EnsemblClinVar. | 1 | |
Natural variantiVAR_074172 | 372 | T → R Found in patients with late onset insulinomas; alters DNA-binding motif; increases transactivation activity; produces a constitutive activation of cAMP and Ca2+ signaling pathways involved in insulin secretion. 2 PublicationsCorresponds to variant dbSNP:rs386834266EnsemblClinVar. | 1 | |
Natural variantiVAR_065086 | 380 | D → Y in GADEVS; reduced DNA-binding; reduced transcription regulator activity. 2 PublicationsCorresponds to variant dbSNP:rs1131692043EnsemblClinVar. | 1 | |
Natural variantiVAR_079208 | 393 | Missing in GADEVS; unknown pathological significance. 1 Publication | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M77698 mRNA Translation: AAA59467.1 M76541 mRNA Translation: AAA59926.1 Z14077 mRNA Translation: CAA78455.1 BC037308 mRNA Translation: AAH37308.1 BC065366 mRNA Translation: AAH65366.1 |
CCDSi | CCDS9957.1 |
PIRi | A40350 |
RefSeqi | NP_003394.1, NM_003403.4 |
Genome annotation databases
Ensembli | ENST00000262238; ENSP00000262238; ENSG00000100811 |
GeneIDi | 7528 |
KEGGi | hsa:7528 |
UCSCi | uc001ygy.3, human |
Keywords - Coding sequence diversityi
PolymorphismSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M77698 mRNA Translation: AAA59467.1 M76541 mRNA Translation: AAA59926.1 Z14077 mRNA Translation: CAA78455.1 BC037308 mRNA Translation: AAH37308.1 BC065366 mRNA Translation: AAH65366.1 |
CCDSi | CCDS9957.1 |
PIRi | A40350 |
RefSeqi | NP_003394.1, NM_003403.4 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1UBD | X-ray | 2.50 | C | 291-414 | [»] | |
1ZNM | NMR | - | A | 352-379 | [»] | |
4C5I | X-ray | 2.59 | C | 199-228 | [»] | |
SMRi | P25490 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 113360, 176 interactors |
ComplexPortali | CPX-846, INO80 chromatin remodeling complex |
CORUMi | P25490 |
DIPi | DIP-150N |
IntActi | P25490, 108 interactors |
MINTi | P25490 |
STRINGi | 9606.ENSP00000262238 |
PTM databases
iPTMneti | P25490 |
PhosphoSitePlusi | P25490 |
Polymorphism and mutation databases
BioMutai | YY1 |
DMDMi | 3915889 |
Proteomic databases
EPDi | P25490 |
jPOSTi | P25490 |
MassIVEi | P25490 |
MaxQBi | P25490 |
PaxDbi | P25490 |
PeptideAtlasi | P25490 |
PRIDEi | P25490 |
ProteomicsDBi | 54279 |
Protocols and materials databases
Antibodypediai | 9, 571 antibodies |
DNASUi | 7528 |
Genome annotation databases
Ensembli | ENST00000262238; ENSP00000262238; ENSG00000100811 |
GeneIDi | 7528 |
KEGGi | hsa:7528 |
UCSCi | uc001ygy.3, human |
Organism-specific databases
CTDi | 7528 |
DisGeNETi | 7528 |
EuPathDBi | HostDB:ENSG00000100811.10 |
GeneCardsi | YY1 |
HGNCi | HGNC:12856, YY1 |
HPAi | ENSG00000100811, Low tissue specificity |
MalaCardsi | YY1 |
MIMi | 600013, gene 617557, phenotype |
neXtProti | NX_P25490 |
OpenTargetsi | ENSG00000100811 |
Orphaneti | 506358, Gabriele-de Vries syndrome |
PharmGKBi | PA37445 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000154763 |
InParanoidi | P25490 |
OMAi | MWASDDN |
OrthoDBi | 1318335at2759 |
PhylomeDBi | P25490 |
TreeFami | TF106493 |
Enzyme and pathway databases
PathwayCommonsi | P25490 |
Reactomei | R-HSA-5617472, Activation of anterior HOX genes in hindbrain development during early embryogenesis R-HSA-5689603, UCH proteinases R-HSA-5696394, DNA Damage Recognition in GG-NER R-HSA-8866910, TFAP2 (AP-2) family regulates transcription of growth factors and their receptors R-HSA-9018519, Estrogen-dependent gene expression |
SignaLinki | P25490 |
SIGNORi | P25490 |
Miscellaneous databases
BioGRID-ORCSi | 7528, 580 hits in 879 CRISPR screens |
ChiTaRSi | YY1, human |
EvolutionaryTracei | P25490 |
GeneWikii | YY1 |
GenomeRNAii | 7528 |
Pharosi | P25490, Tbio |
PROi | PR:P25490 |
RNActi | P25490, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000100811, Expressed in amniotic fluid and 252 other tissues |
ExpressionAtlasi | P25490, baseline and differential |
Genevisiblei | P25490, HS |
Family and domain databases
IDEALi | IID00234 |
InterProi | View protein in InterPro IPR017114, YY1-like IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF00096, zf-C2H2, 3 hits |
PIRSFi | PIRSF037113, TF_Yin_yang, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 4 hits |
SUPFAMi | SSF57667, SSF57667, 3 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 4 hits PS50157, ZINC_FINGER_C2H2_2, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TYY1_HUMAN | |
Accessioni | P25490Primary (citable) accession number: P25490 Secondary accession number(s): Q14935 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1992 |
Last sequence update: | December 15, 1998 | |
Last modified: | December 2, 2020 | |
This is version 229 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families - Human chromosome 14
Human chromosome 14: entries, gene names and cross-references to MIM - Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations