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UniProtKB - P25351 (YCR3_YEAST)
Protein
Uncharacterized membrane protein YCR023C
Gene
YCR023C
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Functioni
GO - Molecular functioni
- transmembrane transporter activity Source: InterPro
Keywordsi
Biological process | Transport |
Names & Taxonomyi
Protein namesi | Recommended name: Uncharacterized membrane protein YCR023C |
Gene namesi | Ordered Locus Names:YCR023C ORF Names:YCR23C, YCR241 |
Organismi | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
Taxonomic identifieri | 559292 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces › |
Proteomesi |
|
Organism-specific databases
SGDi | S000000617, YCR023C |
VEuPathDBi | FungiDB:YCR023C |
Subcellular locationi
Other locations
Vacuole
- fungal-type vacuole membrane Source: SGD
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 89 | ExtracellularSequence analysisAdd BLAST | 89 | |
Transmembranei | 90 – 110 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 111 – 152 | CytoplasmicSequence analysisAdd BLAST | 42 | |
Transmembranei | 153 – 173 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 174 – 199 | ExtracellularSequence analysisAdd BLAST | 26 | |
Transmembranei | 200 – 220 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 221 – 353 | CytoplasmicSequence analysisAdd BLAST | 133 | |
Transmembranei | 354 – 372 | HelicalSequence analysisAdd BLAST | 19 | |
Topological domaini | 373 – 413 | ExtracellularSequence analysisAdd BLAST | 41 | |
Transmembranei | 414 – 434 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 435 – 442 | CytoplasmicSequence analysis | 8 | |
Transmembranei | 443 – 463 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 464 – 542 | ExtracellularSequence analysisAdd BLAST | 79 | |
Transmembranei | 543 – 563 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 564 – 611 | CytoplasmicSequence analysisAdd BLAST | 48 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000173425 | 1 – 611 | Uncharacterized membrane protein YCR023CAdd BLAST | 611 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 313 | PhosphoserineCombined sources | 1 | |
Modified residuei | 603 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
PaxDbi | P25351 |
PRIDEi | P25351 |
PTM databases
iPTMneti | P25351 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 31005, 59 interactors |
DIPi | DIP-1960N |
STRINGi | 4932.YCR023C |
Miscellaneous databases
RNActi | P25351, protein |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 261 – 301 | DisorderedSequence analysisAdd BLAST | 41 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 261 – 284 | Basic and acidic residuesSequence analysisAdd BLAST | 24 | |
Compositional biasi | 285 – 301 | Polar residuesSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Belongs to the major facilitator superfamily.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2615, Eukaryota |
HOGENOMi | CLU_001265_54_5_1 |
InParanoidi | P25351 |
OMAi | LAWWACG |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
i Sequence
Sequence statusi: Complete.
P25351-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MARQKLTFKE QMDGFPWVQL VVVSLVRFSE PIAFSSLFPY VYFMVRDFNI
60 70 80 90 100
APNDAQVSKY SGYLSSSFAL CQVISAYHWG RFSEKHGRKI TLTCGLIGTS
110 120 130 140 150
VSLLILGFSR NFYQALVARS LMGLLNGNVG VIRTIIGEIA TERKHQALAF
160 170 180 190 200
STMPLLFQFG AVVGPMIGGF LVFRDGTMNE VPLWFPHFAK RIIRSYPYAL
210 220 230 240 250
PNVVVCMFLM FGLTNATLFL EETHPAFKDR RDYGLEVGDF IKKNIFGIQP
260 270 280 290 300
KRRPWQKRIQ DDSENIHHRN ENVNSIRGQD SEEDENSPLV NTTNDDDTES
310 320 330 340 350
IQSIDPILTR RQSVGLIRTY SLHEPTDAVH ANIDTAPDGC KESSIFHHVF
360 370 380 390 400
HTKVFYPISV NFIMALHLIV YNEFLPVFLA YDLAVDPENP KKLASKFPWK
410 420 430 440 450
ISGGIGYEPE QTGTLLSTTG IFGCFVVIFI FPIVDRNFDC LTIFRTLVKL
460 470 480 490 500
YPIMYVMVPY VVFLQNERIP SWYTVVYLYI ITGIKTFCGA LTSPQIMLLI
510 520 530 540 550
HNSSPLSCRS VINGATISIS ASARFIGPLV WGYIMSWSQQ NDVAWVSWWS
560 570 580 590 600
LSLFCMVALY QSYKIAPIDD NENELHGQGS EDAYNSQSQS SDLRMAHRSS
610
LSSLSNQRCT T
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X59720 Genomic DNA Translation: CAC42975.1 BK006937 Genomic DNA Translation: DAA07501.1 |
PIRi | S19434 |
RefSeqi | NP_009952.2, NM_001178737.1 |
Genome annotation databases
EnsemblFungii | YCR023C_mRNA; YCR023C; YCR023C |
GeneIDi | 850387 |
KEGGi | sce:YCR023C |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X59720 Genomic DNA Translation: CAC42975.1 BK006937 Genomic DNA Translation: DAA07501.1 |
PIRi | S19434 |
RefSeqi | NP_009952.2, NM_001178737.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 31005, 59 interactors |
DIPi | DIP-1960N |
STRINGi | 4932.YCR023C |
PTM databases
iPTMneti | P25351 |
Proteomic databases
PaxDbi | P25351 |
PRIDEi | P25351 |
Genome annotation databases
EnsemblFungii | YCR023C_mRNA; YCR023C; YCR023C |
GeneIDi | 850387 |
KEGGi | sce:YCR023C |
Organism-specific databases
SGDi | S000000617, YCR023C |
VEuPathDBi | FungiDB:YCR023C |
Phylogenomic databases
eggNOGi | KOG2615, Eukaryota |
HOGENOMi | CLU_001265_54_5_1 |
InParanoidi | P25351 |
OMAi | LAWWACG |
Miscellaneous databases
PROi | PR:P25351 |
RNActi | P25351, protein |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR011701, MFS IPR020846, MFS_dom IPR036259, MFS_trans_sf |
Pfami | View protein in Pfam PF07690, MFS_1, 1 hit |
SUPFAMi | SSF103473, SSF103473, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YCR3_YEAST | |
Accessioni | P25351Primary (citable) accession number: P25351 Secondary accession number(s): D6VR32, Q8NKJ7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 1, 1992 |
Last sequence update: | May 16, 2003 | |
Last modified: | February 23, 2022 | |
This is version 162 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Yeast
Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD - Yeast chromosome III
Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names - SIMILARITY comments
Index of protein domains and families