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Entry version 165 (13 Feb 2019)
Sequence version 1 (01 May 1992)
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Protein

Tumor necrosis factor receptor superfamily member 1B

Gene

Tnfrsf1b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-5668541 TNFR2 non-canonical NF-kB pathway
R-MMU-5669034 TNFs bind their physiological receptors
R-MMU-6798695 Neutrophil degranulation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tumor necrosis factor receptor superfamily member 1B
Alternative name(s):
Tumor necrosis factor receptor 2
Short name:
TNF-R2
Tumor necrosis factor receptor type II
Short name:
TNF-RII
Short name:
TNFR-II
p75
p80 TNF-alpha receptor
CD_antigen: CD120b
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tnfrsf1b
Synonyms:Tnfr-2, Tnfr2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1314883 Tnfrsf1b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini23 – 258ExtracellularSequence analysisAdd BLAST236
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei259 – 288HelicalSequence analysisAdd BLAST30
Topological domaini289 – 474CytoplasmicSequence analysisAdd BLAST186

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Add BLAST22
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000003455023 – 474Tumor necrosis factor receptor superfamily member 1BAdd BLAST452

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi30O-linked (GalNAc...) threonineBy similarity1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi40 ↔ 54PROSITE-ProRule annotation
Disulfide bondi55 ↔ 68PROSITE-ProRule annotation
Disulfide bondi58 ↔ 76PROSITE-ProRule annotation
Glycosylationi69N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi79 ↔ 94PROSITE-ProRule annotation
Disulfide bondi97 ↔ 111PROSITE-ProRule annotation
Disulfide bondi101 ↔ 119PROSITE-ProRule annotation
Disulfide bondi121 ↔ 127PROSITE-ProRule annotation
Disulfide bondi136 ↔ 145PROSITE-ProRule annotation
Disulfide bondi139 ↔ 163PROSITE-ProRule annotation
Disulfide bondi166 ↔ 181PROSITE-ProRule annotation
Glycosylationi195N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi208O-linked (GalNAc...) threonineBy similarity1
Glycosylationi224O-linked (GalNAc...) threonineBy similarity1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei331PhosphoserineBy similarity1

Keywords - PTMi

Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P25119

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P25119

PeptideAtlas

More...
PeptideAtlasi
P25119

PRoteomics IDEntifications database

More...
PRIDEi
P25119

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P25119

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
P25119

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000028599 Expressed in 172 organ(s), highest expression level in bone marrow macrophage

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P25119 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P25119 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to TRAF2. Interacts with BMX. Interacts (activated form) with XPNPEP3.By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
204250, 4 interactors

Database of interacting proteins

More...
DIPi
DIP-60902N

Protein interaction database and analysis system

More...
IntActi
P25119, 4 interactors

Molecular INTeraction database

More...
MINTi
P25119

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000030336

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P25119

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P25119

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati39 – 77TNFR-Cys 1Add BLAST39
Repeati78 – 119TNFR-Cys 2Add BLAST42
Repeati120 – 164TNFR-Cys 3Add BLAST45
Repeati165 – 203TNFR-Cys 4Add BLAST39

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IJ06 Eukaryota
ENOG410YPQW LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161800

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000132845

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG054237

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P25119

KEGG Orthology (KO)

More...
KOi
K05141

Identification of Orthologs from Complete Genome Data

More...
OMAi
CRPHRIC

Database of Orthologous Groups

More...
OrthoDBi
559890at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P25119

TreeFam database of animal gene trees

More...
TreeFami
TF331157

Family and domain databases

Conserved Domains Database

More...
CDDi
cd10577 TNFRSF1B, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR020411 TNFR_1B
IPR033996 TNFRSF1B_N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00020 TNFR_c6, 2 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01919 TNFACTORR1B

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00208 TNFR, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00652 TNFR_NGFR_1, 2 hits
PS50050 TNFR_NGFR_2, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

P25119-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPAALWVAL VFELQLWATG HTVPAQVVLT PYKPEPGYEC QISQEYYDRK
60 70 80 90 100
AQMCCAKCPP GQYVKHFCNK TSDTVCADCE ASMYTQVWNQ FRTCLSCSSS
110 120 130 140 150
CTTDQVEIRA CTKQQNRVCA CEAGRYCALK THSGSCRQCM RLSKCGPGFG
160 170 180 190 200
VASSRAPNGN VLCKACAPGT FSDTTSSTDV CRPHRICSIL AIPGNASTDA
210 220 230 240 250
VCAPESPTLS AIPRTLYVSQ PEPTRSQPLD QEPGPSQTPS ILTSLGSTPI
260 270 280 290 300
IEQSTKGGIS LPIGLIVGVT SLGLLMLGLV NCIILVQRKK KPSCLQRDAK
310 320 330 340 350
VPHVPDEKSQ DAVGLEQQHL LTTAPSSSSS SLESSASAGD RRAPPGGHPQ
360 370 380 390 400
ARVMAEAQGF QEARASSRIS DSSHGSHGTH VNVTCIVNVC SSSDHSSQCS
410 420 430 440 450
SQASATVGDP DAKPSASPKD EQVPFSQEEC PSQSPCETTE TLQSHEKPLP
460 470
LGVPDMGMKP SQAGWFDQIA VKVA
Length:474
Mass (Da):50,320
Last modified:May 1, 1992 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i462EAE398C4D6563
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
D6RG55D6RG55_MOUSE
Tumor necrosis factor receptor supe...
Tnfrsf1b
55Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti78D → DSDTVCAD in CAA74969 (PubMed:9740674).Curated1
Sequence conflicti102T → S in CAA74969 (PubMed:9740674).Curated1
Sequence conflicti108I → T in CAA74969 (PubMed:9740674).Curated1
Sequence conflicti283I → F in CAA74969 (PubMed:9740674).Curated1
Sequence conflicti331S → SS in CAA74969 (PubMed:9740674).Curated1
Sequence conflicti360F → S in CAA74969 (PubMed:9740674).Curated1
Sequence conflicti436C → Y in CAA74969 (PubMed:9740674).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M60469 mRNA Translation: AAA39752.1
M59378 mRNA Translation: AAA40463.1
Y14619
, Y14620, Y14621, Y14622, Y14679, Y14623 Genomic DNA Translation: CAA74969.1
U39488 Genomic DNA Translation: AAA85021.1
X87128 Genomic DNA Translation: CAA60618.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS18914.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B38634

NCBI Reference Sequences

More...
RefSeqi
NP_035740.2, NM_011610.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.235328

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000030336; ENSMUSP00000030336; ENSMUSG00000028599

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
21938

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:21938

UCSC genome browser

More...
UCSCi
uc008vrt.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M60469 mRNA Translation: AAA39752.1
M59378 mRNA Translation: AAA40463.1
Y14619
, Y14620, Y14621, Y14622, Y14679, Y14623 Genomic DNA Translation: CAA74969.1
U39488 Genomic DNA Translation: AAA85021.1
X87128 Genomic DNA Translation: CAA60618.1
CCDSiCCDS18914.1
PIRiB38634
RefSeqiNP_035740.2, NM_011610.3
UniGeneiMm.235328

3D structure databases

ProteinModelPortaliP25119
SMRiP25119
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi204250, 4 interactors
DIPiDIP-60902N
IntActiP25119, 4 interactors
MINTiP25119
STRINGi10090.ENSMUSP00000030336

PTM databases

PhosphoSitePlusiP25119
SwissPalmiP25119

Proteomic databases

EPDiP25119
PaxDbiP25119
PeptideAtlasiP25119
PRIDEiP25119

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030336; ENSMUSP00000030336; ENSMUSG00000028599
GeneIDi21938
KEGGimmu:21938
UCSCiuc008vrt.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7133
MGIiMGI:1314883 Tnfrsf1b

Phylogenomic databases

eggNOGiENOG410IJ06 Eukaryota
ENOG410YPQW LUCA
GeneTreeiENSGT00940000161800
HOGENOMiHOG000132845
HOVERGENiHBG054237
InParanoidiP25119
KOiK05141
OMAiCRPHRIC
OrthoDBi559890at2759
PhylomeDBiP25119
TreeFamiTF331157

Enzyme and pathway databases

ReactomeiR-MMU-5668541 TNFR2 non-canonical NF-kB pathway
R-MMU-5669034 TNFs bind their physiological receptors
R-MMU-6798695 Neutrophil degranulation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Tnfrsf1b mouse

Protein Ontology

More...
PROi
PR:P25119

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000028599 Expressed in 172 organ(s), highest expression level in bone marrow macrophage
ExpressionAtlasiP25119 baseline and differential
GenevisibleiP25119 MM

Family and domain databases

CDDicd10577 TNFRSF1B, 1 hit
InterProiView protein in InterPro
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR020411 TNFR_1B
IPR033996 TNFRSF1B_N
PfamiView protein in Pfam
PF00020 TNFR_c6, 2 hits
PRINTSiPR01919 TNFACTORR1B
SMARTiView protein in SMART
SM00208 TNFR, 4 hits
PROSITEiView protein in PROSITE
PS00652 TNFR_NGFR_1, 2 hits
PS50050 TNFR_NGFR_2, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTNR1B_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P25119
Secondary accession number(s): O88734, P97893
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 1992
Last sequence update: May 1, 1992
Last modified: February 13, 2019
This is version 165 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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