UniProtKB - P24468 (COT2_HUMAN)
COUP transcription factor 2
NR2F2
Functioni
Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A. May be required to establish ovary identity during early gonad development (PubMed:29478779).
4 PublicationsRegions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 76 – 151 | Nuclear receptorPROSITE-ProRule annotationAdd BLAST | 76 | |
Zinc fingeri | 79 – 99 | NR C4-typePROSITE-ProRule annotationAdd BLAST | 21 | |
Zinc fingeri | 115 – 139 | NR C4-typePROSITE-ProRule annotationAdd BLAST | 25 |
GO - Molecular functioni
- DNA-binding transcription factor activity Source: UniProtKB
- nuclear receptor activity Source: UniProtKB
- protein homodimerization activity Source: UniProtKB
- retinoic acid binding Source: UniProtKB
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: UniProtKB
- zinc ion binding Source: InterPro
GO - Biological processi
- anatomical structure development Source: GO_Central
- anterior/posterior pattern specification Source: Ensembl
- blood vessel morphogenesis Source: Ensembl
- cell differentiation Source: GO_Central
- female gonad development Source: UniProtKB
- fertilization Source: Ensembl
- forebrain development Source: Ensembl
- limb development Source: Ensembl
- lymphatic endothelial cell fate commitment Source: BHF-UCL
- maternal placenta development Source: Ensembl
- negative regulation of cyclin-dependent protein serine/threonine kinase activity Source: BHF-UCL
- negative regulation of endothelial cell migration Source: BHF-UCL
- negative regulation of endothelial cell proliferation Source: BHF-UCL
- negative regulation of transcription, DNA-templated Source: BHF-UCL
- negative regulation of transcription by RNA polymerase II Source: UniProtKB
- neuron migration Source: Ensembl
- placenta blood vessel development Source: Ensembl
- positive regulation of systemic arterial blood pressure Source: Ensembl
- positive regulation of transcription, DNA-templated Source: UniProtKB
- positive regulation of transcription by RNA polymerase II Source: BHF-UCL
- radial pattern formation Source: Ensembl
- regulation of transcription by RNA polymerase II Source: GO_Central
- response to estradiol Source: Ensembl
- skeletal muscle tissue development Source: Ensembl
- trophoblast giant cell differentiation Source: Ensembl
Keywordsi
Molecular function | Activator, DNA-binding, Receptor |
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
PathwayCommonsi | P24468 |
Reactomei | R-HSA-381340, Transcriptional regulation of white adipocyte differentiation |
SignaLinki | P24468 |
SIGNORi | P24468 |
Names & Taxonomyi
Protein namesi | Recommended name: COUP transcription factor 2Short name: COUP-TF2 Alternative name(s): Apolipoprotein A-I regulatory protein 1 Short name: ARP-1 COUP transcription factor II Short name: COUP-TF II Nuclear receptor subfamily 2 group F member 2 |
Gene namesi | Name:NR2F2 Synonyms:ARP1, TFCOUP2 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:7976, NR2F2 |
MIMi | 107773, gene |
neXtProti | NX_P24468 |
VEuPathDBi | HostDB:ENSG00000185551 |
Subcellular locationi
Nucleus
Cytosol
- cytosol Source: HPA
Nucleus
- nucleoplasm Source: HPA
- nucleus Source: BHF-UCL
Keywords - Cellular componenti
NucleusPathology & Biotechi
Involvement in diseasei
Congenital heart defects, multiple types, 4 (CHTD4)1 Publication
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_071766 | 75 | Q → QQ in CHTD4; the mutation results in reduced transcription activation of the EGR1 promoter; does not affect transcription activation of the APOB FT promoter. 1 Publication | 1 | |
Natural variantiVAR_071767 | 170 | D → V in CHTD4. 1 Publication | 1 | |
Natural variantiVAR_071768 | 205 | N → I in CHTD4; the mutation results in increased transcription activation of the EGR1 promoter; transcription activation of the APOB promoter is decreased. 1 PublicationCorresponds to variant dbSNP:rs587777372EnsemblClinVar. | 1 | |
Natural variantiVAR_071769 | 251 | E → D in CHTD4. 1 Publication | 1 | |
Natural variantiVAR_071770 | 341 | S → Y in CHTD4; the mutation results in reduced transcriptional activity. 1 PublicationCorresponds to variant dbSNP:rs587777371EnsemblClinVar. | 1 | |
Natural variantiVAR_071771 | 412 | A → S in CHTD4. 1 PublicationCorresponds to variant dbSNP:rs201527820Ensembl. | 1 |
46,XX sex reversal 5 (SRXX5)1 Publication
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 228 | R → E: Reduces transcription activation by 40%; when associated with R-398. 1 Publication | 1 | |
Mutagenesisi | 249 | W → A: Reduces transcription activation by 50%; when associated with A-250. 1 Publication | 1 | |
Mutagenesisi | 250 | S → A: Reduces transcription activation by 50%; when associated with A-249. 1 Publication | 1 | |
Mutagenesisi | 250 | S → W: Reduces transcription activation by 50%. 1 Publication | 1 | |
Mutagenesisi | 253 – 254 | FV → AA: Reduces transcription activation by 50%. 1 Publication | 2 | |
Mutagenesisi | 269 – 270 | LL → AA: Reduces transcription activation by 50%. | 2 | |
Mutagenesisi | 364 – 365 | LL → AA: Reduces transcription activation by 80%. 1 Publication | 2 | |
Mutagenesisi | 398 | D → R: Reduces transcription activation by 40%; when associated with E-228. 1 Publication | 1 |
Keywords - Diseasei
Disease variantOrganism-specific databases
DisGeNETi | 7026 |
MalaCardsi | NR2F2 |
MIMi | 615779, phenotype 618901, phenotype |
OpenTargetsi | ENSG00000185551 |
Orphaneti | 99067, Complete atrioventricular septal defect with ventricular hypoplasia 99068, Complete atrioventricular septal defect-tetralogy of Fallot 1330, Partial atrioventricular septal defect |
PharmGKBi | PA31759 |
Miscellaneous databases
Pharosi | P24468, Tbio |
Chemistry databases
ChEMBLi | CHEMBL1961790 |
Genetic variation databases
BioMutai | NR2F2 |
DMDMi | 114203 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000053606 | 1 – 414 | COUP transcription factor 2Add BLAST | 414 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 51 | PhosphothreonineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | P24468 |
jPOSTi | P24468 |
MassIVEi | P24468 |
MaxQBi | P24468 |
PaxDbi | P24468 |
PeptideAtlasi | P24468 |
PRIDEi | P24468 |
ProteomicsDBi | 54206 [P24468-1] 54207 [P24468-2] 54208 [P24468-3] |
PTM databases
iPTMneti | P24468 |
PhosphoSitePlusi | P24468 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000185551, Expressed in female gonad and 256 other tissues |
ExpressionAtlasi | P24468, baseline and differential |
Genevisiblei | P24468, HS |
Organism-specific databases
HPAi | ENSG00000185551, Tissue enhanced (ovary) |
Interactioni
Subunit structurei
Interacts with SQSTM1 (By similarity). Binds DNA as a dimer; homodimer or heterodimer with NR2F6.
Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A.
Interacts with ZFPM2 (By similarity).
By similarityBinary interactionsi
P24468
With | #Exp. | IntAct |
---|---|---|
SMAD4 [Q13485] | 4 | EBI-2795198,EBI-347263 |
GO - Molecular functioni
- protein homodimerization activity Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 112884, 117 interactors |
CORUMi | P24468 |
DIPi | DIP-29713N |
IntActi | P24468, 53 interactors |
MINTi | P24468 |
STRINGi | 9606.ENSP00000377721 |
Chemistry databases
BindingDBi | P24468 |
Miscellaneous databases
RNActi | P24468, protein |
Structurei
Secondary structure
3D structure databases
SMRi | P24468 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P24468 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 177 – 403 | NR LBDPROSITE-ProRule annotationAdd BLAST | 227 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 72 | DisorderedSequence analysisAdd BLAST | 72 | |
Regioni | 117 – 414 | Interaction with ZFPM2By similarityAdd BLAST | 298 | |
Regioni | 337 – 414 | Important for dimerizationAdd BLAST | 78 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 26 – 41 | Pro residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 43 – 57 | Polar residuesSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 79 – 99 | NR C4-typePROSITE-ProRule annotationAdd BLAST | 21 | |
Zinc fingeri | 115 – 139 | NR C4-typePROSITE-ProRule annotationAdd BLAST | 25 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | KOG3575, Eukaryota |
GeneTreei | ENSGT00940000157540 |
HOGENOMi | CLU_007368_20_1_1 |
InParanoidi | P24468 |
OMAi | FATVNWA |
OrthoDBi | 666130at2759 |
PhylomeDBi | P24468 |
TreeFami | TF352097 |
Family and domain databases
Gene3Di | 1.10.565.10, 1 hit 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR035500, NHR-like_dom_sf IPR000536, Nucl_hrmn_rcpt_lig-bd IPR001723, Nuclear_hrmn_rcpt IPR001628, Znf_hrmn_rcpt IPR013088, Znf_NHR/GATA |
Pfami | View protein in Pfam PF00104, Hormone_recep, 1 hit PF00105, zf-C4, 1 hit |
PRINTSi | PR00398, STRDHORMONER PR00047, STROIDFINGER |
SMARTi | View protein in SMART SM00430, HOLI, 1 hit SM00399, ZnF_C4, 1 hit |
SUPFAMi | SSF48508, SSF48508, 1 hit |
PROSITEi | View protein in PROSITE PS51843, NR_LBD, 1 hit PS00031, NUCLEAR_REC_DBD_1, 1 hit PS51030, NUCLEAR_REC_DBD_2, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MAMVVSTWRD PQDEVPGSQG SQASQAPPVP GPPPGAPHTP QTPGQGGPAS
60 70 80 90 100
TPAQTAAGGQ GGPGGPGSDK QQQQQHIECV VCGDKSSGKH YGQFTCEGCK
110 120 130 140 150
SFFKRSVRRN LSYTCRANRN CPIDQHHRNQ CQYCRLKKCL KVGMRREAVQ
160 170 180 190 200
RGRMPPTQPT HGQFALTNGD PLNCHSYLSG YISLLLRAEP YPTSRFGSQC
210 220 230 240 250
MQPNNIMGIE NICELAARML FSAVEWARNI PFFPDLQITD QVALLRLTWS
260 270 280 290 300
ELFVLNAAQC SMPLHVAPLL AAAGLHASPM SADRVVAFMD HIRIFQEQVE
310 320 330 340 350
KLKALHVDSA EYSCLKAIVL FTSDACGLSD VAHVESLQEK SQCALEEYVR
360 370 380 390 400
SQYPNQPTRF GKLLLRLPSL RTVSSSVIEQ LFFVRLVGKT PIETLIRDML
410
LSGSSFNWPY MAIQ
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketH3BTC2 | H3BTC2_HUMAN | COUP transcription factor 2 | NR2F2 | 93 | Annotation score: |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_071766 | 75 | Q → QQ in CHTD4; the mutation results in reduced transcription activation of the EGR1 promoter; does not affect transcription activation of the APOB FT promoter. 1 Publication | 1 | |
Natural variantiVAR_071767 | 170 | D → V in CHTD4. 1 Publication | 1 | |
Natural variantiVAR_071768 | 205 | N → I in CHTD4; the mutation results in increased transcription activation of the EGR1 promoter; transcription activation of the APOB promoter is decreased. 1 PublicationCorresponds to variant dbSNP:rs587777372EnsemblClinVar. | 1 | |
Natural variantiVAR_071769 | 251 | E → D in CHTD4. 1 Publication | 1 | |
Natural variantiVAR_071770 | 341 | S → Y in CHTD4; the mutation results in reduced transcriptional activity. 1 PublicationCorresponds to variant dbSNP:rs587777371EnsemblClinVar. | 1 | |
Natural variantiVAR_071771 | 412 | A → S in CHTD4. 1 PublicationCorresponds to variant dbSNP:rs201527820Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_043897 | 1 – 153 | Missing in isoform 3. 2 PublicationsAdd BLAST | 153 | |
Alternative sequenceiVSP_042630 | 1 – 147 | MAMVV…GMRRE → MQAVWDLEQGKYGF in isoform 2. 4 PublicationsAdd BLAST | 147 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M64497 mRNA Translation: AAA86429.1 U60477 Genomic DNA Translation: AAB09475.1 AB307711 mRNA Translation: BAH02302.1 FM208183 mRNA Translation: CAR63888.1 AK298824 mRNA Translation: BAG60954.1 AK301595 mRNA Translation: BAG63083.1 AK316086 mRNA Translation: BAH14457.1 HQ692849 mRNA Translation: ADZ17360.1 HQ692850 mRNA Translation: ADZ17361.1 AC016251 Genomic DNA No translation available. CH471101 Genomic DNA Translation: EAX02195.1 CH471101 Genomic DNA Translation: EAX02196.1 CH471101 Genomic DNA Translation: EAX02197.1 BC014664 mRNA Translation: AAH14664.1 BC042897 mRNA Translation: AAH42897.1 BC106083 mRNA Translation: AAI06084.1 M62760 mRNA Translation: AAA21479.1 |
CCDSi | CCDS10375.1 [P24468-1] CCDS45358.1 [P24468-2] CCDS45359.1 [P24468-3] |
PIRi | A37133 |
RefSeqi | NP_001138627.1, NM_001145155.1 [P24468-2] NP_001138628.1, NM_001145156.1 [P24468-3] NP_001138629.1, NM_001145157.1 [P24468-3] NP_066285.1, NM_021005.3 [P24468-1] |
Genome annotation databases
Ensembli | ENST00000394166; ENSP00000377721; ENSG00000185551 ENST00000394171; ENSP00000377726; ENSG00000185551 [P24468-3] ENST00000421109; ENSP00000401674; ENSG00000185551 [P24468-2] ENST00000453270; ENSP00000389853; ENSG00000185551 [P24468-3] |
GeneIDi | 7026 |
KEGGi | hsa:7026 |
MANE-Selecti | ENST00000394166.8; ENSP00000377721.3; NM_021005.4; NP_066285.1 |
UCSCi | uc002btp.4, human [P24468-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M64497 mRNA Translation: AAA86429.1 U60477 Genomic DNA Translation: AAB09475.1 AB307711 mRNA Translation: BAH02302.1 FM208183 mRNA Translation: CAR63888.1 AK298824 mRNA Translation: BAG60954.1 AK301595 mRNA Translation: BAG63083.1 AK316086 mRNA Translation: BAH14457.1 HQ692849 mRNA Translation: ADZ17360.1 HQ692850 mRNA Translation: ADZ17361.1 AC016251 Genomic DNA No translation available. CH471101 Genomic DNA Translation: EAX02195.1 CH471101 Genomic DNA Translation: EAX02196.1 CH471101 Genomic DNA Translation: EAX02197.1 BC014664 mRNA Translation: AAH14664.1 BC042897 mRNA Translation: AAH42897.1 BC106083 mRNA Translation: AAI06084.1 M62760 mRNA Translation: AAA21479.1 |
CCDSi | CCDS10375.1 [P24468-1] CCDS45358.1 [P24468-2] CCDS45359.1 [P24468-3] |
PIRi | A37133 |
RefSeqi | NP_001138627.1, NM_001145155.1 [P24468-2] NP_001138628.1, NM_001145156.1 [P24468-3] NP_001138629.1, NM_001145157.1 [P24468-3] NP_066285.1, NM_021005.3 [P24468-1] |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
3CJW | X-ray | 1.48 | A | 175-414 | [»] | |
SMRi | P24468 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 112884, 117 interactors |
CORUMi | P24468 |
DIPi | DIP-29713N |
IntActi | P24468, 53 interactors |
MINTi | P24468 |
STRINGi | 9606.ENSP00000377721 |
Chemistry databases
BindingDBi | P24468 |
ChEMBLi | CHEMBL1961790 |
PTM databases
iPTMneti | P24468 |
PhosphoSitePlusi | P24468 |
Genetic variation databases
BioMutai | NR2F2 |
DMDMi | 114203 |
Proteomic databases
EPDi | P24468 |
jPOSTi | P24468 |
MassIVEi | P24468 |
MaxQBi | P24468 |
PaxDbi | P24468 |
PeptideAtlasi | P24468 |
PRIDEi | P24468 |
ProteomicsDBi | 54206 [P24468-1] 54207 [P24468-2] 54208 [P24468-3] |
Protocols and materials databases
Antibodypediai | 16260, 329 antibodies from 34 providers |
DNASUi | 7026 |
Genome annotation databases
Ensembli | ENST00000394166; ENSP00000377721; ENSG00000185551 ENST00000394171; ENSP00000377726; ENSG00000185551 [P24468-3] ENST00000421109; ENSP00000401674; ENSG00000185551 [P24468-2] ENST00000453270; ENSP00000389853; ENSG00000185551 [P24468-3] |
GeneIDi | 7026 |
KEGGi | hsa:7026 |
MANE-Selecti | ENST00000394166.8; ENSP00000377721.3; NM_021005.4; NP_066285.1 |
UCSCi | uc002btp.4, human [P24468-1] |
Organism-specific databases
CTDi | 7026 |
DisGeNETi | 7026 |
GeneCardsi | NR2F2 |
HGNCi | HGNC:7976, NR2F2 |
HPAi | ENSG00000185551, Tissue enhanced (ovary) |
MalaCardsi | NR2F2 |
MIMi | 107773, gene 615779, phenotype 618901, phenotype |
neXtProti | NX_P24468 |
OpenTargetsi | ENSG00000185551 |
Orphaneti | 99067, Complete atrioventricular septal defect with ventricular hypoplasia 99068, Complete atrioventricular septal defect-tetralogy of Fallot 1330, Partial atrioventricular septal defect |
PharmGKBi | PA31759 |
VEuPathDBi | HostDB:ENSG00000185551 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG3575, Eukaryota |
GeneTreei | ENSGT00940000157540 |
HOGENOMi | CLU_007368_20_1_1 |
InParanoidi | P24468 |
OMAi | FATVNWA |
OrthoDBi | 666130at2759 |
PhylomeDBi | P24468 |
TreeFami | TF352097 |
Enzyme and pathway databases
PathwayCommonsi | P24468 |
Reactomei | R-HSA-381340, Transcriptional regulation of white adipocyte differentiation |
SignaLinki | P24468 |
SIGNORi | P24468 |
Miscellaneous databases
BioGRID-ORCSi | 7026, 32 hits in 1070 CRISPR screens |
ChiTaRSi | NR2F2, human |
EvolutionaryTracei | P24468 |
GeneWikii | COUP-TFII |
GenomeRNAii | 7026 |
Pharosi | P24468, Tbio |
PROi | PR:P24468 |
RNActi | P24468, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000185551, Expressed in female gonad and 256 other tissues |
ExpressionAtlasi | P24468, baseline and differential |
Genevisiblei | P24468, HS |
Family and domain databases
Gene3Di | 1.10.565.10, 1 hit 3.30.50.10, 1 hit |
InterProi | View protein in InterPro IPR035500, NHR-like_dom_sf IPR000536, Nucl_hrmn_rcpt_lig-bd IPR001723, Nuclear_hrmn_rcpt IPR001628, Znf_hrmn_rcpt IPR013088, Znf_NHR/GATA |
Pfami | View protein in Pfam PF00104, Hormone_recep, 1 hit PF00105, zf-C4, 1 hit |
PRINTSi | PR00398, STRDHORMONER PR00047, STROIDFINGER |
SMARTi | View protein in SMART SM00430, HOLI, 1 hit SM00399, ZnF_C4, 1 hit |
SUPFAMi | SSF48508, SSF48508, 1 hit |
PROSITEi | View protein in PROSITE PS51843, NR_LBD, 1 hit PS00031, NUCLEAR_REC_DBD_1, 1 hit PS51030, NUCLEAR_REC_DBD_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | COT2_HUMAN | |
Accessioni | P24468Primary (citable) accession number: P24468 Secondary accession number(s): B4DQJ2 Q3KQR7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 1, 1992 |
Last sequence update: | March 1, 1992 | |
Last modified: | February 23, 2022 | |
This is version 208 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 15
Human chromosome 15: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families