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Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi614 – 621ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • adenine/cytosine mispair binding Source: EcoliWiki
  • ADP binding Source: EcoliWiki
  • ATPase activity Source: EcoliWiki
  • ATP binding Source: EcoliWiki
  • damaged DNA binding Source: GO_Central
  • DNA binding, bending Source: EcoliWiki
  • DNA-dependent ATPase activity Source: GO_Central
  • identical protein binding Source: IntAct
  • mismatched DNA binding Source: EcoliWiki

GO - Biological processi

  • cellular response to DNA damage stimulus Source: EcoliWiki
  • mismatch repair Source: EcoliWiki
  • regulation of DNA recombination Source: EcoliWiki

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processDNA damage, DNA repair
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
EcoCyc:EG10625-MONOMER
MetaCyc:EG10625-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA mismatch repair protein MutS
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mutS
Synonyms:fdv
Ordered Locus Names:b2733, JW2703
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

Escherichia coli strain K12 genome database

More...
EcoGenei
EG10625 mutS

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

  • cytosol Source: EcoCyc
  • mismatch repair complex Source: EcoliWiki

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001150941 – 853DNA mismatch repair protein MutSAdd BLAST853

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P23909

PRoteomics IDEntifications database

More...
PRIDEi
P23909

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...
SWISS-2DPAGEi
P23909

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
4261421, 143 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-93 DNA mismatch repair MutS complex

Database of interacting proteins

More...
DIPi
DIP-10287N

Protein interaction database and analysis system

More...
IntActi
P23909, 10 interactors

Molecular INTeraction database

More...
MINTi
P23909

STRING: functional protein association networks

More...
STRINGi
316385.ECDH10B_2901

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1853
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P23909

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P23909

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
P23909

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA mismatch repair MutS family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105D86 Bacteria
COG0249 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000221407

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P23909

KEGG Orthology (KO)

More...
KOi
K03555

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P23909

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.420.110, 1 hit
3.40.1170.10, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00096 MutS, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005748 DNA_mismatch_repair_MutS
IPR007695 DNA_mismatch_repair_MutS-lik_N
IPR017261 DNA_mismatch_repair_MutS/MSH
IPR000432 DNA_mismatch_repair_MutS_C
IPR007861 DNA_mismatch_repair_MutS_clamp
IPR007696 DNA_mismatch_repair_MutS_core
IPR016151 DNA_mismatch_repair_MutS_N
IPR036187 DNA_mismatch_repair_MutS_sf
IPR007860 DNA_mmatch_repair_MutS_con_dom
IPR036678 MutS_con_dom_sf
IPR027417 P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01624 MutS_I, 1 hit
PF05188 MutS_II, 1 hit
PF05192 MutS_III, 1 hit
PF05190 MutS_IV, 1 hit
PF00488 MutS_V, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF037677 DNA_mis_repair_Msh6, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00534 MUTSac, 1 hit
SM00533 MUTSd, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48334 SSF48334, 1 hit
SSF52540 SSF52540, 1 hit
SSF53150 SSF53150, 1 hit
SSF55271 SSF55271, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01070 mutS1, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00486 DNA_MISMATCH_REPAIR_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P23909-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSAIENFDAH TPMMQQYLRL KAQHPEILLF YRMGDFYELF YDDAKRASQL
60 70 80 90 100
LDISLTKRGA SAGEPIPMAG IPYHAVENYL AKLVNQGESV AICEQIGDPA
110 120 130 140 150
TSKGPVERKV VRIVTPGTIS DEALLQERQD NLLAAIWQDS KGFGYATLDI
160 170 180 190 200
SSGRFRLSEP ADRETMAAEL QRTNPAELLY AEDFAEMSLI EGRRGLRRRP
210 220 230 240 250
LWEFEIDTAR QQLNLQFGTR DLVGFGVENA PRGLCAAGCL LQYAKDTQRT
260 270 280 290 300
TLPHIRSITM EREQDSIIMD AATRRNLEIT QNLAGGAENT LASVLDCTVT
310 320 330 340 350
PMGSRMLKRW LHMPVRDTRV LLERQQTIGA LQDFTAGLQP VLRQVGDLER
360 370 380 390 400
ILARLALRTA RPRDLARMRH AFQQLPELRA QLETVDSAPV QALREKMGEF
410 420 430 440 450
AELRDLLERA IIDTPPVLVR DGGVIASGYN EELDEWRALA DGATDYLERL
460 470 480 490 500
EVRERERTGL DTLKVGFNAV HGYYIQISRG QSHLAPINYM RRQTLKNAER
510 520 530 540 550
YIIPELKEYE DKVLTSKGKA LALEKQLYEE LFDLLLPHLE ALQQSASALA
560 570 580 590 600
ELDVLVNLAE RAYTLNYTCP TFIDKPGIRI TEGRHPVVEQ VLNEPFIANP
610 620 630 640 650
LNLSPQRRML IITGPNMGGK STYMRQTALI ALMAYIGSYV PAQKVEIGPI
660 670 680 690 700
DRIFTRVGAA DDLASGRSTF MVEMTETANI LHNATEYSLV LMDEIGRGTS
710 720 730 740 750
TYDGLSLAWA CAENLANKIK ALTLFATHYF ELTQLPEKME GVANVHLDAL
760 770 780 790 800
EHGDTIAFMH SVQDGAASKS YGLAVAALAG VPKEVIKRAR QKLRELESIS
810 820 830 840 850
PNAAATQVDG TQMSLLSVPE ETSPAVEALE NLDPDSLTPR QALEWIYRLK

SLV
Length:853
Mass (Da):95,247
Last modified:March 1, 1992 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5A1F295362671D55
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M64730 Genomic DNA Translation: AAA24188.1
U29579 Genomic DNA Translation: AAA69243.1
U00096 Genomic DNA Translation: AAC75775.1
AP009048 Genomic DNA Translation: BAE76810.1
AF004287 Genomic DNA Translation: AAD01197.1
AF001987 Genomic DNA Translation: AAD00921.1
AF001988 Genomic DNA Translation: AAD00922.1
AF001989 Genomic DNA Translation: AAD00923.1
AF001990 Genomic DNA Translation: AAD00924.1
AF001991 Genomic DNA Translation: AAD00925.1
AF001992 Genomic DNA Translation: AAD00926.1
AF001993 Genomic DNA Translation: AAD00927.1
AF001994 Genomic DNA Translation: AAD00928.1
AF001995 Genomic DNA Translation: AAD00929.1
AF001996 Genomic DNA Translation: AAD00930.1
AF001997 Genomic DNA Translation: AAD00931.1
AF001998 Genomic DNA Translation: AAD00932.1
AF001999 Genomic DNA Translation: AAD00933.1
AF002000 Genomic DNA Translation: AAD00934.1
AF002001 Genomic DNA Translation: AAD00935.1
AF002002 Genomic DNA Translation: AAD00936.1
AF002003 Genomic DNA Translation: AAD00937.1
AF002004 Genomic DNA Translation: AAD00938.1
AF002005 Genomic DNA Translation: AAD00939.1
AF002006 Genomic DNA Translation: AAD00940.1
AF002007 Genomic DNA Translation: AAD00941.1
AF002008 Genomic DNA Translation: AAD00942.1
AF002009 Genomic DNA Translation: AAD00943.1
AF002010 Genomic DNA Translation: AAD00944.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I54964

NCBI Reference Sequences

More...
RefSeqi
NP_417213.1, NC_000913.3
WP_001272928.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAC75775; AAC75775; b2733
BAE76810; BAE76810; BAE76810

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
947206

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ecj:JW2703
eco:b2733

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|1411691.4.peg.4007

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64730 Genomic DNA Translation: AAA24188.1
U29579 Genomic DNA Translation: AAA69243.1
U00096 Genomic DNA Translation: AAC75775.1
AP009048 Genomic DNA Translation: BAE76810.1
AF004287 Genomic DNA Translation: AAD01197.1
AF001987 Genomic DNA Translation: AAD00921.1
AF001988 Genomic DNA Translation: AAD00922.1
AF001989 Genomic DNA Translation: AAD00923.1
AF001990 Genomic DNA Translation: AAD00924.1
AF001991 Genomic DNA Translation: AAD00925.1
AF001992 Genomic DNA Translation: AAD00926.1
AF001993 Genomic DNA Translation: AAD00927.1
AF001994 Genomic DNA Translation: AAD00928.1
AF001995 Genomic DNA Translation: AAD00929.1
AF001996 Genomic DNA Translation: AAD00930.1
AF001997 Genomic DNA Translation: AAD00931.1
AF001998 Genomic DNA Translation: AAD00932.1
AF001999 Genomic DNA Translation: AAD00933.1
AF002000 Genomic DNA Translation: AAD00934.1
AF002001 Genomic DNA Translation: AAD00935.1
AF002002 Genomic DNA Translation: AAD00936.1
AF002003 Genomic DNA Translation: AAD00937.1
AF002004 Genomic DNA Translation: AAD00938.1
AF002005 Genomic DNA Translation: AAD00939.1
AF002006 Genomic DNA Translation: AAD00940.1
AF002007 Genomic DNA Translation: AAD00941.1
AF002008 Genomic DNA Translation: AAD00942.1
AF002009 Genomic DNA Translation: AAD00943.1
AF002010 Genomic DNA Translation: AAD00944.1
PIRiI54964
RefSeqiNP_417213.1, NC_000913.3
WP_001272928.1, NZ_LN832404.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1E3MX-ray2.20A/B1-800[»]
1NG9X-ray2.60A/B1-800[»]
1OH5X-ray2.90A/B1-800[»]
1OH6X-ray2.40A/B1-800[»]
1OH7X-ray2.50A/B1-800[»]
1OH8X-ray2.90A/B1-800[»]
1W7AX-ray2.27A/B1-800[»]
1WB9X-ray2.10A/B1-800[»]
1WBBX-ray2.50A/B1-800[»]
1WBDX-ray2.40A/B1-800[»]
2OK2X-ray2.00A/B820-853[»]
2WTUX-ray3.40A/B1-800[»]
3K0SX-ray2.20A/B2-800[»]
3ZLJX-ray3.10A/B1-800[»]
C/D801-853[»]
5AKBX-ray4.71A/B/E1-800[»]
5AKCX-ray6.60A/B/E/F/I/J1-800[»]
5AKDX-ray7.60A/B/E/F/I/J1-800[»]
ProteinModelPortaliP23909
SMRiP23909
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261421, 143 interactors
ComplexPortaliCPX-93 DNA mismatch repair MutS complex
DIPiDIP-10287N
IntActiP23909, 10 interactors
MINTiP23909
STRINGi316385.ECDH10B_2901

2D gel databases

SWISS-2DPAGEiP23909

Proteomic databases

PaxDbiP23909
PRIDEiP23909

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75775; AAC75775; b2733
BAE76810; BAE76810; BAE76810
GeneIDi947206
KEGGiecj:JW2703
eco:b2733
PATRICifig|1411691.4.peg.4007

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...
EchoBASEi
EB0620
EcoGeneiEG10625 mutS

Phylogenomic databases

eggNOGiENOG4105D86 Bacteria
COG0249 LUCA
HOGENOMiHOG000221407
InParanoidiP23909
KOiK03555
PhylomeDBiP23909

Enzyme and pathway databases

BioCyciEcoCyc:EG10625-MONOMER
MetaCyc:EG10625-MONOMER

Miscellaneous databases

EvolutionaryTraceiP23909

Protein Ontology

More...
PROi
PR:P23909

Family and domain databases

Gene3Di3.30.420.110, 1 hit
3.40.1170.10, 1 hit
HAMAPiMF_00096 MutS, 1 hit
InterProiView protein in InterPro
IPR005748 DNA_mismatch_repair_MutS
IPR007695 DNA_mismatch_repair_MutS-lik_N
IPR017261 DNA_mismatch_repair_MutS/MSH
IPR000432 DNA_mismatch_repair_MutS_C
IPR007861 DNA_mismatch_repair_MutS_clamp
IPR007696 DNA_mismatch_repair_MutS_core
IPR016151 DNA_mismatch_repair_MutS_N
IPR036187 DNA_mismatch_repair_MutS_sf
IPR007860 DNA_mmatch_repair_MutS_con_dom
IPR036678 MutS_con_dom_sf
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF01624 MutS_I, 1 hit
PF05188 MutS_II, 1 hit
PF05192 MutS_III, 1 hit
PF05190 MutS_IV, 1 hit
PF00488 MutS_V, 1 hit
PIRSFiPIRSF037677 DNA_mis_repair_Msh6, 1 hit
SMARTiView protein in SMART
SM00534 MUTSac, 1 hit
SM00533 MUTSd, 1 hit
SUPFAMiSSF48334 SSF48334, 1 hit
SSF52540 SSF52540, 1 hit
SSF53150 SSF53150, 1 hit
SSF55271 SSF55271, 1 hit
TIGRFAMsiTIGR01070 mutS1, 1 hit
PROSITEiView protein in PROSITE
PS00486 DNA_MISMATCH_REPAIR_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMUTS_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P23909
Secondary accession number(s): P71279, Q2MA96
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: November 7, 2018
This is version 161 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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