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Protein

Oligodendrocyte-myelin glycoprotein

Gene

OMG

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.

Caution

Do not confuse oligodendrocyte-myelin glycoprotein (OMG) with myelin-oligodendrocyte glycoprotein (MOG).Curated

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

  • cell adhesion Source: UniProtKB-KW
  • negative regulation of axonogenesis Source: Reactome
  • neuron projection regeneration Source: GO_Central

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-HSA-193634 Axonal growth inhibition (RHOA activation)

SIGNOR Signaling Network Open Resource

More...
SIGNORi
P23515

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Oligodendrocyte-myelin glycoprotein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:OMG
Synonyms:OMGP
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000126861.4

Human Gene Nomenclature Database

More...
HGNCi
HGNC:8135 OMG

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
164345 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_P23515

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
4974

Open Targets

More...
OpenTargetsi
ENSG00000126861

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA31922

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
OMG

Domain mapping of disease mutations (DMDM)

More...
DMDMi
129122

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 241 PublicationAdd BLAST24
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000002188825 – 417Oligodendrocyte-myelin glycoproteinAdd BLAST393
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_0000021889418 – 440Removed in mature formSequence analysisAdd BLAST23

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi45N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi61N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi103N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi152N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi176N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi189N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi192N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi234N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi364N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi389N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi417GPI-anchor amidated serineSequence analysis1
Glycosylationi425N-linked (GlcNAc...) asparagineSequence analysis1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

O-glycosylated in its Ser/Thr-rich repeat domain.Curated

Keywords - PTMi

Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P23515

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P23515

PeptideAtlas

More...
PeptideAtlasi
P23515

PRoteomics IDEntifications database

More...
PRIDEi
P23515

ProteomicsDB human proteome resource

More...
ProteomicsDBi
54125

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
P23515

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P23515

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P23515

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Oligodendrocytes and myelin of the central nervous system.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000126861 Expressed in 142 organ(s), highest expression level in bronchial epithelial cell

CleanEx database of gene expression profiles

More...
CleanExi
HS_OMG

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P23515 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA008206
HPA012693

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to RTN4R.1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
111022, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000247271

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
P23515

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
P23515

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini25 – 55LRRNTAdd BLAST31
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati56 – 77LRR 1Add BLAST22
Repeati79 – 100LRR 2Add BLAST22
Repeati101 – 121LRR 3Add BLAST21
Repeati124 – 145LRR 4Add BLAST22
Repeati147 – 168LRR 5Add BLAST22
Repeati169 – 189LRR 6Add BLAST21
Repeati192 – 213LRR 7Add BLAST22
Repeati216 – 239LRR 8Add BLAST24
Repeati229 – 270Ser/Thr-richAdd BLAST42
Repeati271 – 292Ser/Thr-richAdd BLAST22
Repeati293 – 335Ser/Thr-richAdd BLAST43
Repeati336 – 377Ser/Thr-richAdd BLAST42
Repeati378 – 416Ser/Thr-richAdd BLAST39

Keywords - Domaini

Leucine-rich repeat, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0619 Eukaryota
COG4886 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160802

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000115267

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG007868

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P23515

KEGG Orthology (KO)

More...
KOi
K16666

Identification of Orthologs from Complete Genome Data

More...
OMAi
KEHNIYP

Database of Orthologous Groups

More...
OrthoDBi
EOG091G08JZ

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P23515

TreeFam database of animal gene trees

More...
TreeFami
TF335688

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.80.10.10, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR000372 LRRNT

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00560 LRR_1, 1 hit
PF13855 LRR_8, 1 hit
PF01462 LRRNT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00369 LRR_TYP, 5 hits
SM00013 LRRNT, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51450 LRR, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P23515-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEYQILKMSL CLFILLFLTP GILCICPLQC ICTERHRHVD CSGRNLSTLP
60 70 80 90 100
SGLQENIIHL NLSYNHFTDL HNQLTQYTNL RTLDISNNRL ESLPAHLPRS
110 120 130 140 150
LWNMSAANNN IKLLDKSDTA YQWNLKYLDV SKNMLEKVVL IKNTLRSLEV
160 170 180 190 200
LNLSSNKLWT VPTNMPSKLH IVDLSNNSLT QILPGTLINL TNLTHLYLHN
210 220 230 240 250
NKFTFIPDQS FDQLFQLQEI TLYNNRWSCD HKQNITYLLK WMMETKAHVI
260 270 280 290 300
GTPCSTQISS LKEHNMYPTP SGFTSSLFTV SGMQTVDTIN SLSVVTQPKV
310 320 330 340 350
TKIPKQYRTK ETTFGATLSK DTTFTSTDKA FVPYPEDTST ETINSHEAAA
360 370 380 390 400
ATLTIHLQDG MVTNTSLTSS TKSSPTPMTL SITSGMPNNF SEMPQQSTTL
410 420 430 440
NLWREETTTN VKTPLPSVAN AWKVNASFLL LLNVVVMLAV
Length:440
Mass (Da):49,608
Last modified:May 1, 1992 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i762FD0E8905EA050
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05125221G → D. Corresponds to variant dbSNP:rs11080149Ensembl.1
Natural variantiVAR_051253435V → A. Corresponds to variant dbSNP:rs16972169EnsemblClinVar.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M63623 mRNA Translation: AAA59970.1 Sequence problems.
X57436 Genomic DNA Translation: CAA40684.1
X51694 mRNA Translation: CAA35991.1 Sequence problems.
CH471147 Genomic DNA Translation: EAW80279.1
CH471147 Genomic DNA Translation: EAW80280.1
BC018050 mRNA Translation: AAH18050.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS11265.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A36688 A39613

NCBI Reference Sequences

More...
RefSeqi
NP_002535.3, NM_002544.4

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.113874

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000247271; ENSP00000247271; ENSG00000126861

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
4974

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:4974

UCSC genome browser

More...
UCSCi
uc002hgj.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63623 mRNA Translation: AAA59970.1 Sequence problems.
X57436 Genomic DNA Translation: CAA40684.1
X51694 mRNA Translation: CAA35991.1 Sequence problems.
CH471147 Genomic DNA Translation: EAW80279.1
CH471147 Genomic DNA Translation: EAW80280.1
BC018050 mRNA Translation: AAH18050.1
CCDSiCCDS11265.1
PIRiA36688 A39613
RefSeqiNP_002535.3, NM_002544.4
UniGeneiHs.113874

3D structure databases

ProteinModelPortaliP23515
SMRiP23515
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi111022, 1 interactor
STRINGi9606.ENSP00000247271

PTM databases

iPTMnetiP23515
PhosphoSitePlusiP23515

Polymorphism and mutation databases

BioMutaiOMG
DMDMi129122

Proteomic databases

MaxQBiP23515
PaxDbiP23515
PeptideAtlasiP23515
PRIDEiP23515
ProteomicsDBi54125
TopDownProteomicsiP23515

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
4974
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000247271; ENSP00000247271; ENSG00000126861
GeneIDi4974
KEGGihsa:4974
UCSCiuc002hgj.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4974
DisGeNETi4974
EuPathDBiHostDB:ENSG00000126861.4

GeneCards: human genes, protein and diseases

More...
GeneCardsi
OMG
HGNCiHGNC:8135 OMG
HPAiHPA008206
HPA012693
MIMi164345 gene
neXtProtiNX_P23515
OpenTargetsiENSG00000126861
PharmGKBiPA31922

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG0619 Eukaryota
COG4886 LUCA
GeneTreeiENSGT00940000160802
HOGENOMiHOG000115267
HOVERGENiHBG007868
InParanoidiP23515
KOiK16666
OMAiKEHNIYP
OrthoDBiEOG091G08JZ
PhylomeDBiP23515
TreeFamiTF335688

Enzyme and pathway databases

ReactomeiR-HSA-193634 Axonal growth inhibition (RHOA activation)
SIGNORiP23515

Miscellaneous databases

The Gene Wiki collection of pages on human genes and proteins

More...
GeneWikii
OMG_(gene)

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
4974

Protein Ontology

More...
PROi
PR:P23515

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000126861 Expressed in 142 organ(s), highest expression level in bronchial epithelial cell
CleanExiHS_OMG
GenevisibleiP23515 HS

Family and domain databases

Gene3Di3.80.10.10, 3 hits
InterProiView protein in InterPro
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR000372 LRRNT
PfamiView protein in Pfam
PF00560 LRR_1, 1 hit
PF13855 LRR_8, 1 hit
PF01462 LRRNT, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 5 hits
SM00013 LRRNT, 1 hit
PROSITEiView protein in PROSITE
PS51450 LRR, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOMGP_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P23515
Secondary accession number(s): E1P659
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: May 1, 1992
Last modified: December 5, 2018
This is version 173 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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