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Entry version 138 (07 Apr 2021)
Sequence version 1 (01 Nov 1991)
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Protein

Flagellar motor switch protein FliM

Gene

fliM

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processChemotaxis, Flagellar rotation

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
BSUB:BSU16310-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Flagellar motor switch protein FliM
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:fliM
Ordered Locus Names:BSU16310
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBacillus subtilis (strain 168)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri224308 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001570 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Bacterial flagellum, Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001809221 – 332Flagellar motor switch protein FliMAdd BLAST332

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P23453

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
224308.BSU16310

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
P23453

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FliM family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG1868, Bacteria

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P23453

Identification of Orthologs from Complete Genome Data

More...
OMAi
NPQFTQI

Database for complete collections of gene phylogenies

More...
PhylomeDBi
P23453

Family and domain databases

Conserved Domains Database

More...
CDDi
cd17908, FliM, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.330.10, 1 hit
3.40.1550.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028976, CheC-like_sf
IPR001689, Flag_FliM
IPR001543, SpoA
IPR036429, SpoA-like_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02154, FliM, 1 hit
PF01052, FliMN_C, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002888, FliM, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00955, FLGMOTORFLIM

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101801, SSF101801, 1 hit
SSF103039, SSF103039, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01397, fliM_switch, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P23453-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGEVLSQNE IDALLSAIST GEMDAEELKK EEKEKKVKVY DFKRALRFSK
60 70 80 90 100
DQIRSLTRIH DNFARLLTTH FSAQLRTYIH ISVSSVDQVP YEEFIRSIPN
110 120 130 140 150
MTILNLFDVH PMEGRIMMEV NPTIAYTMMD RVMGGIGISH NKVDSLTEIE
160 170 180 190 200
TKIISNLFEN ALGNYKEAWQ SIADIEPEMT EFEVNPQFVQ MVSPNETVVV
210 220 230 240 250
ISLNTQIGEI SGVINLCIPH IVLEPLIPKL SVHYWMQSDR NEPKPEETKS
260 270 280 290 300
LEKRIMTAQI PVVAELGTSE LTIEEFLSLE VGDCITLDKS VTDPLTVLVG
310 320 330
DKPKFLGQAG RVNRKQAVQI LDHDIRGEQD GE
Length:332
Mass (Da):37,529
Last modified:November 1, 1991 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5078D0B54E8D08E5
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence CAA39530 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
M37691 Genomic DNA Translation: AAA22446.1
AL009126 Genomic DNA Translation: CAB13504.1
X56049 Genomic DNA Translation: CAA39530.1 Different initiation.
M86738 Genomic DNA Translation: AAA22448.1

Protein sequence database of the Protein Information Resource

More...
PIRi
B39136

NCBI Reference Sequences

More...
RefSeqi
NP_389513.1, NC_000964.3
WP_003220879.1, NZ_JNCM01000035.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
CAB13504; CAB13504; BSU_16310

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
939518

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bsu:BSU16310

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|224308.179.peg.1772

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37691 Genomic DNA Translation: AAA22446.1
AL009126 Genomic DNA Translation: CAB13504.1
X56049 Genomic DNA Translation: CAA39530.1 Different initiation.
M86738 Genomic DNA Translation: AAA22448.1
PIRiB39136
RefSeqiNP_389513.1, NC_000964.3
WP_003220879.1, NZ_JNCM01000035.1

3D structure databases

SMRiP23453
ModBaseiSearch...

Protein-protein interaction databases

STRINGi224308.BSU16310

Proteomic databases

PaxDbiP23453

Genome annotation databases

EnsemblBacteriaiCAB13504; CAB13504; BSU_16310
GeneIDi939518
KEGGibsu:BSU16310
PATRICifig|224308.179.peg.1772

Phylogenomic databases

eggNOGiCOG1868, Bacteria
InParanoidiP23453
OMAiNPQFTQI
PhylomeDBiP23453

Enzyme and pathway databases

BioCyciBSUB:BSU16310-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:P23453

Family and domain databases

CDDicd17908, FliM, 1 hit
Gene3Di2.30.330.10, 1 hit
3.40.1550.10, 1 hit
InterProiView protein in InterPro
IPR028976, CheC-like_sf
IPR001689, Flag_FliM
IPR001543, SpoA
IPR036429, SpoA-like_sf
PfamiView protein in Pfam
PF02154, FliM, 1 hit
PF01052, FliMN_C, 1 hit
PIRSFiPIRSF002888, FliM, 1 hit
PRINTSiPR00955, FLGMOTORFLIM
SUPFAMiSSF101801, SSF101801, 1 hit
SSF103039, SSF103039, 1 hit
TIGRFAMsiTIGR01397, fliM_switch, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiFLIM_BACSU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P23453
Secondary accession number(s): Q57518
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: April 7, 2021
This is version 138 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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