UniProtKB - P23269 (O1496_RAT)
Protein
Olfactory receptor 1496
Gene
Olr1496
Organism
Rattus norvegicus (Rat)
Status
Functioni
Odorant receptor.Curated
GO - Molecular functioni
- G protein-coupled receptor activity Source: UniProtKB-KW
- olfactory receptor activity Source: GO_Central
GO - Biological processi
- G protein-coupled receptor signaling pathway Source: GO_Central
Keywordsi
Molecular function | G-protein coupled receptor, Receptor, Transducer |
Biological process | Olfaction, Sensory transduction |
Enzyme and pathway databases
Reactomei | R-RNO-381753 Olfactory Signaling Pathway |
Names & Taxonomyi
Protein namesi | Recommended name: Olfactory receptor 1496Alternative name(s): Olfactory receptor-like protein I3 |
Gene namesi | Name:Olr1496 |
Organismi | Rattus norvegicus (Rat) |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1332757 Olr1496 |
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 23 | ExtracellularSequence analysisAdd BLAST | 23 | |
Transmembranei | 24 – 48 | Helical; Name=1Sequence analysisAdd BLAST | 25 | |
Topological domaini | 49 – 55 | CytoplasmicSequence analysis | 7 | |
Transmembranei | 56 – 77 | Helical; Name=2Sequence analysisAdd BLAST | 22 | |
Topological domaini | 78 – 98 | ExtracellularSequence analysisAdd BLAST | 21 | |
Transmembranei | 99 – 118 | Helical; Name=3Sequence analysisAdd BLAST | 20 | |
Topological domaini | 119 – 137 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 138 – 156 | Helical; Name=4Sequence analysisAdd BLAST | 19 | |
Topological domaini | 157 – 194 | ExtracellularSequence analysisAdd BLAST | 38 | |
Transmembranei | 195 – 217 | Helical; Name=5Sequence analysisAdd BLAST | 23 | |
Topological domaini | 218 – 234 | CytoplasmicSequence analysisAdd BLAST | 17 | |
Transmembranei | 235 – 258 | Helical; Name=6Sequence analysisAdd BLAST | 24 | |
Topological domaini | 259 – 270 | ExtracellularSequence analysisAdd BLAST | 12 | |
Transmembranei | 271 – 290 | Helical; Name=7Sequence analysisAdd BLAST | 20 | |
Topological domaini | 291 – 310 | CytoplasmicSequence analysisAdd BLAST | 20 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000150875 | 1 – 310 | Olfactory receptor 1496Add BLAST | 310 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 3 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 95 ↔ 187 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bond, GlycoproteinProteomic databases
PaxDbi | P23269 |
PRIDEi | P23269 |
Expressioni
Tissue specificityi
Olfactory epithelium.
Family & Domainsi
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG410JDAH Eukaryota ENOG410YB92 LUCA |
HOGENOMi | HOG000041362 |
InParanoidi | P23269 |
PhylomeDBi | P23269 |
Family and domain databases
InterProi | View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000725 Olfact_rcpt |
Pfami | View protein in Pfam PF13853 7tm_4, 1 hit |
PRINTSi | PR00237 GPCRRHODOPSN PR00245 OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
P23269-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNNQTFITQF LLLGLPIPEE HQHLFYALFL VMYLTTILGN LLIIVLVQLD
60 70 80 90 100
SQLHTPMYLF LSNLSFSDLC FSSVTMPKLL QNMRSQDTSI PYGGCLAQTY
110 120 130 140 150
FFMVFGDMES FLLVAMAYDR YVAICFPLHY TSIMSPKLCT CLVLLLWMLT
160 170 180 190 200
TSHAMMHTLL AARLSFCENN VVLNFFCDLF VLLKLACSDT YINELMIFIM
210 220 230 240 250
STLLIIIPFF LIVMSYARII SSILKVPSTQ GICKVFSTCG SHLSVVSLFY
260 270 280 290 300
GTIIGLYLCP AGNNSTVKEM VMAMMYTVVT PMLNPFIYSL RNRDMKRALI
310
RVICSMKITL
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketM0RBK2 | M0RBK2_RAT | Olfactory receptor | LOC100909578 Olr1496, rCG_35398 | 310 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M64385 mRNA Translation: AAA41748.1 |
PIRi | E23701 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M64385 mRNA Translation: AAA41748.1 |
PIRi | E23701 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
GPCRDBi | Search... |
Proteomic databases
PaxDbi | P23269 |
PRIDEi | P23269 |
Organism-specific databases
RGDi | 1332757 Olr1496 |
Phylogenomic databases
eggNOGi | ENOG410JDAH Eukaryota ENOG410YB92 LUCA |
HOGENOMi | HOG000041362 |
InParanoidi | P23269 |
PhylomeDBi | P23269 |
Enzyme and pathway databases
Reactomei | R-RNO-381753 Olfactory Signaling Pathway |
Miscellaneous databases
PROi | PR:P23269 |
Family and domain databases
InterProi | View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000725 Olfact_rcpt |
Pfami | View protein in Pfam PF13853 7tm_4, 1 hit |
PRINTSi | PR00237 GPCRRHODOPSN PR00245 OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | O1496_RAT | |
Accessioni | P23269Primary (citable) accession number: P23269 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1991 |
Last sequence update: | November 1, 1991 | |
Last modified: | October 16, 2019 | |
This is version 113 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- 7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries - SIMILARITY comments
Index of protein domains and families