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UniProtKB - P23262 (NHG1_PSEPU)
Protein
Salicylate hydroxylase
Gene
nahG
Organism
Pseudomonas putida (Arthrobacter siderocapsulatus)
Status
Functioni
Catalytic activityi
- EC:1.14.13.1
Cofactori
: naphthalene degradation Pathwayi
This protein is involved in the pathway naphthalene degradation, which is part of Aromatic compound metabolism.View all proteins of this organism that are known to be involved in the pathway naphthalene degradation and in Aromatic compound metabolism.
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 9 – 38 | FADSequence analysisAdd BLAST | 30 |
GO - Molecular functioni
- FAD binding Source: InterPro
- salicylate 1-monooxygenase activity Source: UniProtKB-EC
GO - Biological processi
- aromatic compound catabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Monooxygenase, Oxidoreductase |
Biological process | Aromatic hydrocarbons catabolism |
Ligand | FAD, Flavoprotein, NAD |
Enzyme and pathway databases
UniPathwayi | UPA00082 |
Names & Taxonomyi
Protein namesi | Recommended name: Salicylate hydroxylase (EC:1.14.13.1)Alternative name(s): Salicylate 1-monooxygenase |
Gene namesi | Name:nahG |
Encoded oni | Plasmid NAH7 |
Organismi | Pseudomonas putida (Arthrobacter siderocapsulatus) |
Taxonomic identifieri | 303 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Initiator methioninei | Removed2 Publications | |||
ChainiPRO_0000096803 | 2 – 434 | Salicylate hydroxylaseAdd BLAST | 433 |
Interactioni
Subunit structurei
Monomer.
1 PublicationStructurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | P23262 |
SMRi | P23262 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Family and domain databases
Gene3Di | 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR002938, FAD-bd IPR036188, FAD/NAD-bd_sf IPR017631, Salicylate_mOase |
Pfami | View protein in Pfam PF01494, FAD_binding_3, 2 hits |
SUPFAMi | SSF51905, SSF51905, 1 hit |
TIGRFAMsi | TIGR03219, salicylate_mono, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P23262-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKNNKLGLRI GIVGGGISGV ALALELCRYS HIQVQLFEAA PAFGEVGAGV
60 70 80 90 100
SFGPNAVRAI VGLGLGEAYL QVADRTSEPW EDVWFEWRRG SDASYLGATI
110 120 130 140 150
APGVGQSSVH RADFIDALVT HLPEGIAQFG KRATQVEQQG GEVQVLFTDG
160 170 180 190 200
TEYRCDLLIG ADGIKSALRS HVLEGQGLAP QVPRFSGTCA YRGMVDSLHL
210 220 230 240 250
REAYRAHGID EHLVDVPQMY LGLDGHILTF PVRNGGIINV VAFISDRSEP
260 270 280 290 300
KPTWPADAPW VREASQREML DAFAGWGDAA RALLECIPAP TLWALHDLAE
310 320 330 340 350
LPGYVHGRVV LIGDAAHAML PHQGAGAGQG LEDAYFLARL LGDTQADAGN
360 370 380 390 400
LAELLEAYDD LRRPRACRVQ QTSWETGELY ELRDPVVGAN EQLLGENLAT
410 420 430
RFDWLWNHDL DTDLAEARAR LGWEHGGGGA LRQG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M60055 Genomic DNA Translation: AAA25897.1 |
PIRi | A39181 |
RefSeqi | WP_011475386.1, NC_007926.1 YP_534831.1, NC_007926.1 |
Genome annotation databases
KEGGi | ag:AAA25897 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M60055 Genomic DNA Translation: AAA25897.1 |
PIRi | A39181 |
RefSeqi | WP_011475386.1, NC_007926.1 YP_534831.1, NC_007926.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
6BZ5 | X-ray | 2.01 | A/B | 1-434 | [»] | |
AlphaFoldDBi | P23262 | |||||
SMRi | P23262 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Genome annotation databases
KEGGi | ag:AAA25897 |
Enzyme and pathway databases
UniPathwayi | UPA00082 |
Family and domain databases
Gene3Di | 3.50.50.60, 1 hit |
InterProi | View protein in InterPro IPR002938, FAD-bd IPR036188, FAD/NAD-bd_sf IPR017631, Salicylate_mOase |
Pfami | View protein in Pfam PF01494, FAD_binding_3, 2 hits |
SUPFAMi | SSF51905, SSF51905, 1 hit |
TIGRFAMsi | TIGR03219, salicylate_mono, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | NHG1_PSEPU | |
Accessioni | P23262Primary (citable) accession number: P23262 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1991 |
Last sequence update: | January 23, 2007 | |
Last modified: | May 25, 2022 | |
This is version 98 of the entry and version 4 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, PlasmidDocuments
- PATHWAY comments
Index of metabolic and biosynthesis pathways - PDB cross-references
Index of Protein Data Bank (PDB) cross-references