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Entry version 152 (22 Apr 2020)
Sequence version 2 (19 Jul 2004)
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Protein

Putative helicase MOV-10

Gene

Mov10

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC (By similarity). In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2 (By similarity). Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1. Facilitates LINE-1 uridylation by TUT4 and TUT7 (By similarity). Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (PubMed:28662698). May function as a messenger ribonucleoprotein (mRNP) clearance factor (By similarity).By similarity1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi525 – 532ATPBy similarity8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicase, Hydrolase, RNA-binding
Biological processRNA-mediated gene silencing
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative helicase MOV-10 (EC:3.6.4.13)
Alternative name(s):
Moloney leukemia virus 10 protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Mov10
Synonyms:Gb110
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:97054 Mov10

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Knockout leads to early embryonic lethality.1 Publication

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi531K → A: Abolishes inhibition of retrotransposition. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000807051 – 1004Putative helicase MOV-10Add BLAST1004

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei148N6-acetyllysineBy similarity1
Modified residuei254PhosphothreonineBy similarity1
Modified residuei433PhosphoserineBy similarity1
Modified residuei970PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
P23249

MaxQB - The MaxQuant DataBase

More...
MaxQBi
P23249

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
P23249

PRoteomics IDEntifications database

More...
PRIDEi
P23249

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
P23249

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
P23249

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

As early as embryonic day 18, there is a higher level of expression in the whole brain compared to adults. Expression continues to rise at birth (P0) and remains elevated over adult levels until P10-P14, when it begins to decline (PubMed:28662698). Highly expressed throughout the P1 brain, including the cortex, hippocampus, cerebellum, midbrain, and hindbrain, there is very little expression in the adult brain except in the hippocampus (PubMed:28662698).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000002227 Expressed in epithelium of small intestine and 181 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
P23249 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
P23249 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with DICER1, AGO2, TARBP2, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC).

Interacts with APOBEC3G in an RNA-dependent manner.

Interacts with TRIM71 (via NHL repeats) in an RNA-dependent manner (PubMed:28662698) (By similarity).

Interacts with both protein products of LIRE1, ORF1p and ORF2p (PubMed:28662698).

Interacts with TUT4 and, to a lesser extent, TUT7; the interactions are RNA-dependent.

Interacts with AGO2, TNRC6B and UPF1; the interactions are direct and RNA-dependent.

Interacts with FMR1; this interaction is direct, occurs in an RNA-dependent manner on polysomes and induces association of MOV10 with RNAs (By similarity).

Interacts with SHFL; the interaction increases in presence of RNA (By similarity).

By similarity1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
201471, 6 interactors

Database of interacting proteins

More...
DIPi
DIP-48575N

Protein interaction database and analysis system

More...
IntActi
P23249, 4 interactors

Molecular INTeraction database

More...
MINTi
P23249

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000126897

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
P23249 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni922 – 966Interaction with AGO2 and APOBEC3GBy similarityAdd BLAST45

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi646 – 649DEAG box4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1804 Eukaryota
COG1112 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156024

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
P23249

KEGG Orthology (KO)

More...
KOi
K18422

Identification of Orthologs from Complete Genome Data

More...
OMAi
PLNPHIN

Database of Orthologous Groups

More...
OrthoDBi
286011at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR041679 DNA2/NAM7-like_AAA
IPR026122 MOV-10
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR10887:SF419 PTHR10887:SF419, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13087 AAA_12, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

P23249-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPSKFSCRKL RETGQRFESF LAERGLDLET DRERLRTIYN HDFKPSYGTP
60 70 80 90 100
APGFSSMLYG MKIANLAFVT KTRVRFFKLD RWADVQLPEK RRIKPGSNIS
110 120 130 140 150
KQHRSLLARI FHDRAEYLHG KHGVDVEVQG PHEARDGQLL IHLDLNRKEV
160 170 180 190 200
LTLRLRNGGS KPVTLTHLFP LCWTPQFVFY HGEQDLPCPL GPGESYELHI
210 220 230 240 250
YCKTSIVGYF PATVLWELLG PGESGAEGAE TFYIARFLAA VAHSPLAAQL
260 270 280 290 300
KPTTPFKRPP RLTRNSVLTN RIEEGERPDR AKGYELELSL ALGTYYPPIL
310 320 330 340 350
LRQLLPTLLQ GPSIFTAPKE VAEIKAQLET TLKSRNYEVK LRLLLHLEEL
360 370 380 390 400
QMEHDIRHYD LDSVPMTWDP VDQNPRLLTL EVPGVAESRP SVLRGDHLFA
410 420 430 440 450
LLSSETQQDD PVTYKGFVHK VELDRVKLSF STSLLSRFVD GLTFKVNFTF
460 470 480 490 500
NRQPLRVQHR ALELTGRWVL WPMLFPVASR GVSLLPSDVK FKLYDRSLES
510 520 530 540 550
NPEQLQAMKH IVRGTTRPAP YIIFGPPGTG KTVTLVEAIK QVVKHLPKAH
560 570 580 590 600
ILACAPSNSG ADLLCQRLRV HLPSSIYRLL APSRDIRMVP EDIKTCCNWD
610 620 630 640 650
AKKGEYVYPA KKHLQQYRVL ITTLITASRL VSAQFPIDHF THIFIDEAGH
660 670 680 690 700
CMEPESLVAI AGLMDVKETG NPGGQLVLAG DPRQLGPVLR SPLALKHGLG
710 720 730 740 750
YSLLERLLAY NSLYKKGPNG YDPQFITKLL RNYRSHPTIL DIPNQLYYDG
760 770 780 790 800
ELQACADVVD RERFCRWEGL PQQGFPIIFH GVMGKDEREG NSPSFFNPEE
810 820 830 840 850
AATVTSYLKQ LLAPSSKKGK ARLSPRNVGV ISPYRKQVEK IRYCITKLDR
860 870 880 890 900
ELRGLDDIKD LKVGSVEEFQ GQERSVILIS TVRSSQSFVQ LDLDFNLGFL
910 920 930 940 950
KNPKRFNVAV TRAKALLIVV GNPLLLGHDP DWKTFLEFCK ENGGYTGCPF
960 970 980 990 1000
PAKLDLQQGQ DLLQGLSKLS PSTSGPRRHQ NLPQEREGEG GLPLQVEPEW

RNEL
Length:1,004
Mass (Da):113,583
Last modified:July 19, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8B2522AAB35B6F2B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PW39E9PW39_MOUSE
Putative helicase MOV-10
Mov10
1,077Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YVL0D3YVL0_MOUSE
Putative helicase MOV-10
Mov10
1,077Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3Z3E8D3Z3E8_MOUSE
Putative helicase MOV-10
Mov10
1,004Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YYR1D3YYR1_MOUSE
Putative helicase MOV-10
Mov10
145Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YVL1D3YVL1_MOUSE
Putative helicase MOV-10
Mov10
57Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti142H → R in CAA36803 (PubMed:1899287).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X52574 mRNA Translation: CAA36803.1
AK004542 mRNA Translation: BAB23358.1
BC053743 mRNA Translation: AAH53743.1
X75819 Genomic DNA Translation: CAA53453.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS38579.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A39611

NCBI Reference Sequences

More...
RefSeqi
NP_001156912.1, NM_001163440.1
NP_001156913.1, NM_001163441.1
NP_032645.2, NM_008619.2
XP_006501163.1, XM_006501100.1
XP_006501164.1, XM_006501101.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000168015; ENSMUSP00000128246; ENSMUSG00000002227

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
17454

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:17454

UCSC genome browser

More...
UCSCi
uc008qum.3 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52574 mRNA Translation: CAA36803.1
AK004542 mRNA Translation: BAB23358.1
BC053743 mRNA Translation: AAH53743.1
X75819 Genomic DNA Translation: CAA53453.1
CCDSiCCDS38579.1
PIRiA39611
RefSeqiNP_001156912.1, NM_001163440.1
NP_001156913.1, NM_001163441.1
NP_032645.2, NM_008619.2
XP_006501163.1, XM_006501100.1
XP_006501164.1, XM_006501101.3

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi201471, 6 interactors
DIPiDIP-48575N
IntActiP23249, 4 interactors
MINTiP23249
STRINGi10090.ENSMUSP00000126897

PTM databases

iPTMnetiP23249
PhosphoSitePlusiP23249

Proteomic databases

EPDiP23249
MaxQBiP23249
PaxDbiP23249
PRIDEiP23249

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
20136 158 antibodies

Genome annotation databases

EnsembliENSMUST00000168015; ENSMUSP00000128246; ENSMUSG00000002227
GeneIDi17454
KEGGimmu:17454
UCSCiuc008qum.3 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4343
MGIiMGI:97054 Mov10

Phylogenomic databases

eggNOGiKOG1804 Eukaryota
COG1112 LUCA
GeneTreeiENSGT00940000156024
InParanoidiP23249
KOiK18422
OMAiPLNPHIN
OrthoDBi286011at2759

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Mov10 mouse

Protein Ontology

More...
PROi
PR:P23249
RNActiP23249 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000002227 Expressed in epithelium of small intestine and 181 other tissues
ExpressionAtlasiP23249 baseline and differential
GenevisibleiP23249 MM

Family and domain databases

InterProiView protein in InterPro
IPR041679 DNA2/NAM7-like_AAA
IPR026122 MOV-10
IPR027417 P-loop_NTPase
PANTHERiPTHR10887:SF419 PTHR10887:SF419, 1 hit
PfamiView protein in Pfam
PF13087 AAA_12, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMOV10_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P23249
Secondary accession number(s): Q9DC64
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: July 19, 2004
Last modified: April 22, 2020
This is version 152 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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