UniProtKB - P23030 (XYNB_CELJU)
Protein
Endo-1,4-beta-xylanase B
Gene
xynB
Organism
Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa)
Status
Functioni
Xylanase B contributes to hydrolyze hemicellulose, the major component of plant cell-walls.
Catalytic activityi
- Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. EC:3.2.1.8
: hemicellulose degradation Pathwayi
This protein is involved in the pathway hemicellulose degradation, which is part of Glycan metabolism.View all proteins of this organism that are known to be involved in the pathway hemicellulose degradation and in Glycan metabolism.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 431 | Proton donorBy similarity | 1 | |
Active sitei | 530 | NucleophilePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- endo-1,4-beta-xylanase activity Source: UniProtKB-EC
- polysaccharide binding Source: InterPro
GO - Biological processi
- cellulose catabolic process Source: UniProtKB-KW
- xylan catabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | Glycosidase, Hydrolase |
Biological process | Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation, Xylan degradation |
Enzyme and pathway databases
BioCyci | CJAP498211:G1GB3-3269-MONOMER |
UniPathwayi | UPA00697 |
Protein family/group databases
CAZyi | CBM2, Carbohydrate-Binding Module Family 2 CBM35, Carbohydrate-Binding Module Family 35 GH10, Glycoside Hydrolase Family 10 |
Names & Taxonomyi
Protein namesi | Recommended name: Endo-1,4-beta-xylanase B (EC:3.2.1.8)Short name: Xylanase B Alternative name(s): 1,4-beta-D-xylan xylanohydrolase B |
Gene namesi | Name:xynB Synonyms:xyn10B Ordered Locus Names:CJA_3280 |
Organismi | Cellvibrio japonicus (strain Ueda107) (Pseudomonas fluorescens subsp. cellulosa) |
Taxonomic identifieri | 498211 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Cellvibrionales › Cellvibrionaceae › Cellvibrio › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 37 | 1 PublicationAdd BLAST | 37 | |
ChainiPRO_0000007978 | 38 – 599 | Endo-1,4-beta-xylanase BAdd BLAST | 562 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 39 ↔ 133 | By similarity |
Keywords - PTMi
Disulfide bondProteomic databases
PRIDEi | P23030 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 38 – 136 | CBM2PROSITE-ProRule annotationAdd BLAST | 99 | |
Domaini | 163 – 289 | CBM6PROSITE-ProRule annotationAdd BLAST | 127 | |
Domaini | 315 – 595 | GH10PROSITE-ProRule annotationAdd BLAST | 281 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 135 – 162 | Ser-rich (linker)Add BLAST | 28 | |
Compositional biasi | 300 – 320 | Ser-rich (linker)Add BLAST | 21 |
Sequence similaritiesi
Belongs to the glycosyl hydrolase 10 (cellulase F) family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG3693, Bacteria |
HOGENOMi | CLU_029617_0_0_6 |
OrthoDBi | 593041at2 |
Family and domain databases
Gene3Di | 2.60.120.260, 1 hit 2.60.40.290, 1 hit |
InterProi | View protein in InterPro IPR001919, CBD2 IPR008965, CBM2/CBM3_carb-bd_dom_sf IPR012291, CBM2_carb-bd_dom_sf IPR018366, CBM2_CS IPR005084, CMB_fam6 IPR008979, Galactose-bd-like_sf IPR001000, GH10 IPR031158, GH10_AS IPR017853, Glycoside_hydrolase_SF |
Pfami | View protein in Pfam PF00553, CBM_2, 1 hit PF03422, CBM_6, 1 hit PF00331, Glyco_hydro_10, 1 hit |
PRINTSi | PR00134, GLHYDRLASE10 |
SMARTi | View protein in SMART SM00637, CBD_II, 1 hit SM00633, Glyco_10, 1 hit |
SUPFAMi | SSF49384, SSF49384, 1 hit SSF49785, SSF49785, 1 hit SSF51445, SSF51445, 1 hit |
PROSITEi | View protein in PROSITE PS51173, CBM2, 1 hit PS00561, CBM2_A, 1 hit PS51175, CBM6, 1 hit PS00591, GH10_1, 1 hit PS51760, GH10_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P23030-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTISASDYRH PGNFLKRTTA LLCVGTALTA LAFNASAACT YTIDSEWSTG
60 70 80 90 100
FTANITLKND TGAAINNWNV NWQYSSNRMT SGWNANFSGT NPYNATNMSW
110 120 130 140 150
NGSIAPGQSI SFGLQGEKNG STAERPTVTG AACNSATTSS VASSSSTPTT
160 170 180 190 200
SSSSASSVAS ALLLQEAQAG FCRVDGTIDN NHTGFTGSGF ANTNNAQGAA
210 220 230 240 250
VVWAIDATSS GRRTLTIRYA NGGTANRNGS LVINGGSNGN YTVSLPTTGA
260 270 280 290 300
WTTWQTATID VDLVQGNNIV QLSATTAEGL PNIDSLSVVG GTVRAGNCGS
310 320 330 340 350
VSSSSSVQSS SSSSSSSAAS AKKFIGNITT SGAVRSDFTR YWNQITPENE
360 370 380 390 400
SKWGSVEGTR NVYNWAPLDR IYAYARQNNI PVKAHTFVWG AQSPSWLNNL
410 420 430 440 450
SGPEVAVEIE QWIRDYCARY PDTAMIDVVN EAVPGHQPAG YAQRAFGNNW
460 470 480 490 500
IQRVFQLARQ YCPNSILILN DYNNIRWQHN EFIALAKAQG NYIDAVGLQA
510 520 530 540 550
HELKGMTAAQ VKTAIDNIWN QVGKPIYISE YDIGDTNDQV QLQNFQAHFP
560 570 580 590
VFYNHPHVHG ITLWGYVVGR TWIEGSGLIQ DNGTPRPAMT WLINNYLNQ
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 563 – 598 | LWGYV…NNYLN → SGICGGQDLDRRLRFDPGQW HTAPGNDVVD in CAA38389 (PubMed:2125205).CuratedAdd BLAST | 36 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X54523 Genomic DNA Translation: CAA38389.1 CP000934 Genomic DNA Translation: ACE84499.1 |
RefSeqi | WP_012488856.1, NC_010995.1 |
Genome annotation databases
EnsemblBacteriai | ACE84499; ACE84499; CJA_3280 |
KEGGi | cja:CJA_3280 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X54523 Genomic DNA Translation: CAA38389.1 CP000934 Genomic DNA Translation: ACE84499.1 |
RefSeqi | WP_012488856.1, NC_010995.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 498211.CJA_3280 |
Protein family/group databases
CAZyi | CBM2, Carbohydrate-Binding Module Family 2 CBM35, Carbohydrate-Binding Module Family 35 GH10, Glycoside Hydrolase Family 10 |
Proteomic databases
PRIDEi | P23030 |
Genome annotation databases
EnsemblBacteriai | ACE84499; ACE84499; CJA_3280 |
KEGGi | cja:CJA_3280 |
Phylogenomic databases
eggNOGi | COG3693, Bacteria |
HOGENOMi | CLU_029617_0_0_6 |
OrthoDBi | 593041at2 |
Enzyme and pathway databases
UniPathwayi | UPA00697 |
BioCyci | CJAP498211:G1GB3-3269-MONOMER |
Family and domain databases
Gene3Di | 2.60.120.260, 1 hit 2.60.40.290, 1 hit |
InterProi | View protein in InterPro IPR001919, CBD2 IPR008965, CBM2/CBM3_carb-bd_dom_sf IPR012291, CBM2_carb-bd_dom_sf IPR018366, CBM2_CS IPR005084, CMB_fam6 IPR008979, Galactose-bd-like_sf IPR001000, GH10 IPR031158, GH10_AS IPR017853, Glycoside_hydrolase_SF |
Pfami | View protein in Pfam PF00553, CBM_2, 1 hit PF03422, CBM_6, 1 hit PF00331, Glyco_hydro_10, 1 hit |
PRINTSi | PR00134, GLHYDRLASE10 |
SMARTi | View protein in SMART SM00637, CBD_II, 1 hit SM00633, Glyco_10, 1 hit |
SUPFAMi | SSF49384, SSF49384, 1 hit SSF49785, SSF49785, 1 hit SSF51445, SSF51445, 1 hit |
PROSITEi | View protein in PROSITE PS51173, CBM2, 1 hit PS00561, CBM2_A, 1 hit PS51175, CBM6, 1 hit PS00591, GH10_1, 1 hit PS51760, GH10_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | XYNB_CELJU | |
Accessioni | P23030Primary (citable) accession number: P23030 Secondary accession number(s): B3PEH8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1991 |
Last sequence update: | April 20, 2010 | |
Last modified: | December 2, 2020 | |
This is version 129 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Direct protein sequencing, Reference proteomeDocuments
- Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries - PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families