UniProtKB - P23006 (DHMH_PARVE)
Protein
Methylamine dehydrogenase heavy chain
Gene
mauB
Organism
Paracoccus versutus (Thiobacillus versutus)
Status
Functioni
Methylamine dehydrogenase carries out the oxidation of methylamine. Electrons are passed from methylamine dehydrogenase to amicyanin.
Catalytic activityi
- EC:1.4.9.1
GO - Molecular functioni
- amine dehydrogenase activity Source: UniProtKB-EC
- methylamine dehydrogenase (amicyanin) activity Source: UniProtKB-EC
GO - Biological processi
- methylamine metabolic process Source: InterPro
Keywordsi
Molecular function | Oxidoreductase |
Biological process | Electron transport, Transport |
Enzyme and pathway databases
BioCyci | MetaCyc:MONOMER-3901 |
Names & Taxonomyi
Protein namesi | Recommended name: Methylamine dehydrogenase heavy chain (EC:1.4.9.1)Short name: MADH Alternative name(s): Methylamine dehydrogenase (amicyanin) |
Gene namesi | Name:mauB Synonyms:madA |
Organismi | Paracoccus versutus (Thiobacillus versutus) |
Taxonomic identifieri | 34007 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhodobacterales › Rhodobacteraceae › Paracoccus |
Subcellular locationi
GO - Cellular componenti
- periplasmic space Source: UniProtKB-SubCell
Keywords - Cellular componenti
PeriplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 31 | Sequence analysisAdd BLAST | 31 | |
ChainiPRO_0000025581 | 32 – 426 | Methylamine dehydrogenase heavy chainAdd BLAST | 395 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 221 ↔ 236 |
Keywords - PTMi
Disulfide bondInteractioni
Subunit structurei
Tetramer of two light and two heavy chains.
Protein-protein interaction databases
STRINGi | 34007.IT40_03135 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | P23006 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | P23006 |
Family & Domainsi
Sequence similaritiesi
Belongs to the aromatic amine dehydrogenase heavy chain family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | COG3391, Bacteria |
OrthoDBi | 302683at2 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR013476, MeN_DH_Hvc IPR009451, Metamine_DH_Hvc IPR011044, Quino_amine_DH_bsu IPR015943, WD40/YVTN_repeat-like_dom_sf |
Pfami | View protein in Pfam PF06433, Me-amine-dh_H, 1 hit |
SUPFAMi | SSF50969, SSF50969, 1 hit |
TIGRFAMsi | TIGR02658, TTQ_MADH_Hv, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
P23006-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASARESTPR YLTLIGATLA CSALALGAAQ AQTEPAEPEA PAETAAADAA
60 70 80 90 100
GQTEGQRGAA EAAAALAAGE ADEPVILEAP APDARRVYIQ DPAHFAAITQ
110 120 130 140 150
QFVIDGSTGR ILGMTDGGFL PHPVAAEDGS FFAQASTVFE RIARGKRTDY
160 170 180 190 200
VEVFDPVTFL PIADIELPDA PRFLVGTYQW MNALTPDNKN LLFYQFSPAP
210 220 230 240 250
AVGVVDLEGK TFDRMLDVPD CYHIFPASPT VFYMNCRDGS LARVDFADGE
260 270 280 290 300
TKVTNTEVFH TEDELLINHP AFSLRSGRLV WPTYTGKIFQ ADLTAEGATF
310 320 330 340 350
RAPIEALTEA ERADDWRPGG WQQTAYHRQS DRIYLLVDQR DEWKHKAASR
360 370 380 390 400
FVVVLNAETG ERINKIELGH EIDSINVSQD AEPLLYALSA GTQTLHIYDA
410 420
ATGEELRSVD QLGRGPQIIT THDMDS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L08575 Genomic DNA Translation: AAA72335.1 |
PIRi | A36934 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | L08575 Genomic DNA Translation: AAA72335.1 |
PIRi | A36934 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1MAE | X-ray | 2.80 | H | 59-400 | [»] | |
1MAF | X-ray | 2.60 | H | 59-400 | [»] | |
2MAD | X-ray | 2.25 | H | 59-400 | [»] | |
3C75 | X-ray | 2.50 | H/J | 1-426 | [»] | |
SMRi | P23006 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 34007.IT40_03135 |
Phylogenomic databases
eggNOGi | COG3391, Bacteria |
OrthoDBi | 302683at2 |
Enzyme and pathway databases
BioCyci | MetaCyc:MONOMER-3901 |
Miscellaneous databases
EvolutionaryTracei | P23006 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR013476, MeN_DH_Hvc IPR009451, Metamine_DH_Hvc IPR011044, Quino_amine_DH_bsu IPR015943, WD40/YVTN_repeat-like_dom_sf |
Pfami | View protein in Pfam PF06433, Me-amine-dh_H, 1 hit |
SUPFAMi | SSF50969, SSF50969, 1 hit |
TIGRFAMsi | TIGR02658, TTQ_MADH_Hv, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DHMH_PARVE | |
Accessioni | P23006Primary (citable) accession number: P23006 Secondary accession number(s): Q60052 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 1, 1991 |
Last sequence update: | November 1, 1997 | |
Last modified: | August 12, 2020 | |
This is version 108 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families