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Protein

Heterocyst differentiation ATP-binding protein HepA

Gene

hepA

Organism
Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Acts early in the process of morphological differentiation of heterocysts.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi397 – 404ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Heterocyst differentiation ATP-binding protein HepA
Gene namesi
Name:hepA
Synonyms:hetA
Ordered Locus Names:alr2835
OrganismiNostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)
Taxonomic identifieri103690 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000002483 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei33 – 53HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei77 – 97HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei163 – 182HelicalPROSITE-ProRule annotationAdd BLAST20
Transmembranei186 – 208HelicalPROSITE-ProRule annotationAdd BLAST23
Transmembranei290 – 310HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000923391 – 607Heterocyst differentiation ATP-binding protein HepAAdd BLAST607

Expressioni

Inductioni

By deprivation of nitrate.

Keywords - Developmental stagei

Heterocyst

Interactioni

Protein-protein interaction databases

STRINGi103690.alr2835

Structurei

3D structure databases

ProteinModelPortaliP22638
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 330ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST299
Domaini364 – 598ABC transporterPROSITE-ProRule annotationAdd BLAST235

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105BZ1 Bacteria
COG1132 LUCA
KOiK06147
OMAiTRAHGDL
OrthoDBiPOG091H00DB

Family and domain databases

Gene3Di1.20.1560.10, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 1 hit
PF00005 ABC_tran, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
SSF90123 SSF90123, 1 hit
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 1 hit
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 1 hit

Sequencei

Sequence statusi: Complete.

P22638-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPKSPHKLFK ANSFWKENNL ILREIKHFRK IAILAVIFSF LAASFEGVSI
60 70 80 90 100
GFLLSFLQKL TSPNDPIQTG ISWVDMILAA DAWPIPPIYR ISLLILLSTW
110 120 130 140 150
MRATFNYFGG VYTESAQLNL ADRLHKQIFE QLQALRLSYF AQTRSGELIN
160 170 180 190 200
TITTEIERIK QGFSGLAFVL TRIMTVCVYF VVMFSISWQL SIISVLIFLL
210 220 230 240 250
LAVGLSTLNK RVRETSFGIS HANAQFTAVA VEFINGIRTI QAFGTQEFER
260 270 280 290 300
QRFYKASTNQ LNAAIKVVLA WTLVKPIAEG IATTVLISLI VISFATFTLP
310 320 330 340 350
VASLLTFFFV LVRVIPNIQD INGTVAFLST LQGSSENIKN ILQTNNKPYL
360 370 380 390 400
KNGKLHFQGL KRSIDLVSVD FGYTADNLVL NNITLTIERG KTTALVGASG
410 420 430 440 450
AGKTTLADLI PRFYDPTEGQ ILVDGLDVQY FEINSLRRKM AVVSQDTFIF
460 470 480 490 500
NTSIRDNIAY GTSGASEAEI REVARLANAL QFIEEMPEGF DTKLGDRGVR
510 520 530 540 550
LSGGQRQRIA IARALLRDPE ILILDEATSA LDSVSERLIQ ESIEKLSVGR
560 570 580 590 600
TVIAIAHRLS TIAKADKVVV MEQGRIVEQG NYQELLEQRG KLWKYHQMQH

ESGQTNS
Length:607
Mass (Da):67,790
Last modified:January 23, 2002 - v3
Checksum:iB47970D4758F564F
GO

Sequence cautioni

The sequence AAC32400 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF031959 Genomic DNA Translation: AAC32400.1 Different initiation.
BA000019 Genomic DNA Translation: BAB74534.1
PIRiAD2160
RefSeqiWP_010996986.1, NC_003272.1

Genome annotation databases

EnsemblBacteriaiBAB74534; BAB74534; BAB74534
KEGGiana:alr2835

Similar proteinsi

Entry informationi

Entry nameiHEPA_NOSS1
AccessioniPrimary (citable) accession number: P22638
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: January 23, 2002
Last modified: March 28, 2018
This is version 121 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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