Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - P22523 (MUKB_ECOLI)

Entry version 184 (13 Nov 2019)
Sequence version 2 (15 Jul 1998)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Chromosome partition protein MukB

Gene

mukB

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organizes and compacts chromosomes. May achieve or facilitate chromosome segregation by condensation of DNA from both sides of a centrally located replisome during cell division. Stimulates both DNA relaxation and to a lesser extent decatenation activity of topoisomerase IV.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes a region in the protein which binds nucleotide phosphates. It always involves more than one amino acid and includes all residues involved in nucleotide-binding.<p><a href='/help/np_bind' target='_top'>More...</a></p>Nucleotide bindingi34 – 41ATPSequence analysis8

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-binding
Biological processCell cycle, Cell division, Chromosome partition, DNA condensation
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...BioCyci		EcoCyc:EG10618-MONOMER
ECOL316407:JW0907-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chromosome partition protein MukB
Alternative name(s):
Structural maintenance of chromosome-related protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mukB
Ordered Locus Names:b0924, JW0907
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coli (strain K12)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri83333 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Escherichia ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000318 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Complete GO annotation on QuickGO ...

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi33S → F in mukB106; no effect. 1 Publication1
Mutagenesisi40K → L: No effect. 1 Publication1
Mutagenesisi688E → A: Does not rescue a ts-mutant of MukB. 1 Publication1
Mutagenesisi692D → A: Does not rescue a ts-mutant of MukB; less binding of ParC. 1 Publication1
Mutagenesisi1201D → N in mukB33; no effect. 1 Publication1
Mutagenesisi1381V → L: Abolishes DNA-binding, but remains associated with MukE and MukF. 1 Publication1
Mutagenesisi1403L → P: Abolishes association with MukE and MukF, but still binds DNA. 1 Publication1
Mutagenesisi1404F → L: No effect. 1 Publication1
Mutagenesisi1406D → N: No effect. 1 Publication1
Mutagenesisi1428M → L: No effect. 1 Publication1
Mutagenesisi1429Q → R: Abolishes association with MukE and MukF, but still binds DNA. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000682141 – 1486Chromosome partition protein MukBAdd BLAST1486

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		P22523

jPOST - Japan Proteome Standard Repository/Database

More...jPOSTi		P22523

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		P22523

PRoteomics IDEntifications database

More...PRIDEi		P22523

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimerization via its hinge domain. Binds to DNA via its C-terminal region.

Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium.

Interacts with tubulin-related protein FtsZ.

Identified in a complex with SpoT; IscS and ACP.

Interacts with the ParC subunit of topoisomerase IV.

5 Publications

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

WithEntry#Exp.IntActNotes
P0AFI211EBI-542943,EBI-878544

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		4261687, 403 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...ComplexPortali		CPX-1090 MukBEF condensin complex

Database of interacting proteins

More...DIPi		DIP-10273N

Protein interaction database and analysis system

More...IntActi		P22523, 58 interactors

Molecular INTeraction database

More...MINTi		P22523

STRING: functional protein association networks

More...STRINGi		511145.b0924

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11486
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P22523

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P22523

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni645 – 804Sufficient for ParC bindingAdd BLAST160
Regioni666 – 783Flexible hingeAdd BLAST118

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili326 – 418Sequence analysisAdd BLAST93
Coiled coili444 – 480Sequence analysisAdd BLAST37
Coiled coili509 – 603Sequence analysisAdd BLAST95
Coiled coili835 – 923Sequence analysisAdd BLAST89
Coiled coili977 – 1115Sequence analysisAdd BLAST139
Coiled coili1209 – 1266Sequence analysisAdd BLAST58

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer. The N- and C-terminus together form the head domain.

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SMC family. MukB subfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG4105DUC Bacteria
COG3096 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000278243

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		P22523

KEGG Orthology (KO)

More...KOi		K03632

Database for complete collections of gene phylogenies

More...PhylomeDBi		P22523

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.20.1060.30, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_01800 MukB, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR012090 MukB
IPR032520 MukB_hinge
IPR042501 MukB_hinge_sf
IPR007406 MukB_N_dom
IPR027417 P-loop_NTPase

Pfam protein domain database

More...Pfami		View protein in Pfam
PF04310 MukB, 1 hit
PF16330 MukB_hinge, 1 hit

PIRSF; a whole-protein classification database

More...PIRSFi		PIRSF005246 MukB, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540 SSF52540, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

P22523-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIERGKFRSL TLINWNGFFA RTFDLDELVT TLSGGNGAGK STTMAAFVTA 
        60         70         80         90        100
LIPDLTLLHF RNTTEAGATS GSRDKGLHGK LKAGVCYSML DTINSRHQRV 
       110        120        130        140        150
VVGVRLQQVA GRDRKVDIKP FAIQGLPMSV QPTQLVTETL NERQARVLPL 
       160        170        180        190        200
NELKDKLEAM EGVQFKQFNS ITDYHSLMFD LGIIARRLRS ASDRSKFYRL 
       210        220        230        240        250
IEASLYGGIS SAITRSLRDY LLPENSGVRK AFQDMEAALR ENRMTLEAIR 
       260        270        280        290        300
VTQSDRDLFK HLISEATNYV AADYMRHANE RRVHLDKALE FRRELHTSRQ 
       310        320        330        340        350
QLAAEQYKHV DMARELAEHN GAEGDLEADY QAASDHLNLV QTALRQQEKI 
       360        370        380        390        400
ERYEADLDEL QIRLEEQNEV VAEAIERQQE NEARAEAAEL EVDELKSQLA 
       410        420        430        440        450
DYQQALDVQQ TRAIQYNQAI AALNRAKELC HLPDLTADCA AEWLETFQAK 
       460        470        480        490        500
ELEATEKMLS LEQKMSMAQT AHSQFEQAYQ LVVAINGPLA RNEAWDVARE 
       510        520        530        540        550
LLREGVDQRH LAEQVQPLRM RLSELEQRLR EQQEAERLLA DFCKRQGKNF 
       560        570        580        590        600
DIDELEALHQ ELEARIASLS DSVSNAREER MALRQEQEQL QSRIQSLMQR 
       610        620        630        640        650
APVWLAAQNS LNQLSEQCGE EFTSSQDVTE YLQQLLERER EAIVERDEVG 
       660        670        680        690        700
ARKNAVDEEI ERLSQPGGSE DQRLNALAER FGGVLLSEIY DDVSLEDAPY 
       710        720        730        740        750
FSALYGPSRH AIVVPDLSQV TEHLEGLTDC PEDLYLIEGD PQSFDDSVFS 
       760        770        780        790        800
VDELEKAVVV KIADRQWRYS RFPEVPLFGR AARESRIESL HAEREVLSER 
       810        820        830        840        850
FATLSFDVQK TQRLHQAFSR FIGSHLAVAF ESDPEAEIRQ LNSRRVELER 
       860        870        880        890        900
ALSNHENDNQ QQRIQFEQAK EGVTALNRIL PRLNLLADDS LADRVDEIRE 
       910        920        930        940        950
RLDEAQEAAR FVQQFGNQLA KLEPIVSVLQ SDPEQFEQLK EDYAYSQQMQ 
       960        970        980        990       1000
RDARQQAFAL TEVVQRRAHF SYSDSAEMLS GNSDLNEKLR ERLEQAEAER 
      1010       1020       1030       1040       1050
TRAREALRGH AAQLSQYNQV LASLKSSYDT KKELLNDLQR ELQDIGVRAD 
      1060       1070       1080       1090       1100
SGAEERARIR RDELHAQLSN NRSRRNQLEK ALTFCEAEMD NLTRKLRKLE 
      1110       1120       1130       1140       1150
RDYFEMREQV VTAKAGWCAV MRMVKDNGVE RRLHRRELAY LSADDLRSMS 
      1160       1170       1180       1190       1200
DKALGALRLA VADNEHLRDV LRMSEDPKRP ERKIQFFVAV YQHLRERIRQ 
      1210       1220       1230       1240       1250
DIIRTDDPVE AIEQMEIELS RLTEELTSRE QKLAISSRSV ANIIRKTIQR 
      1260       1270       1280       1290       1300
EQNRIRMLNQ GLQNVSFGQV NSVRLNVNVR ETHAMLLDVL SEQHEQHQDL 
      1310       1320       1330       1340       1350
FNSNRLTFSE ALAKLYQRLN PQIDMGQRTP QTIGEELLDY RNYLEMEVEV 
      1360       1370       1380       1390       1400
NRGSDGWLRA ESGALSTGEA IGTGMSILVM VVQSWEDESR RLRGKDISPC 
      1410       1420       1430       1440       1450
RLLFLDEAAR LDARSIATLF ELCERLQMQL IIAAPENISP EKGTTYKLVR 
      1460       1470       1480 
KVFQNTEHVH VVGLRGFAPQ LPETLPGTDE APSQAS
Length:1,486
Mass (Da):170,230
Last modified:July 15, 1998 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i38C7874BEB78D6D6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti266A → R in CAA40776 (PubMed:1989883).Curated1
Sequence conflicti266A → R in BAA06510 (PubMed:7988894).Curated1
Sequence conflicti318 – 319EH → DD in CAA40776 (PubMed:1989883).Curated2
Sequence conflicti1134H → D in CAA40776 (PubMed:1989883).Curated1
Sequence conflicti1174 – 1175SE → VQ in CAA40776 (PubMed:1989883).Curated2
Sequence conflicti1276 – 1277Missing in CAA40776 (PubMed:1989883).Curated2
Sequence conflicti1276 – 1277Missing in BAA06510 (PubMed:7988894).Curated2
Sequence conflicti1357 – 1380WLRAE…SILVM → CCAQSLVHCRPVRRWYRYVD SGV in CAA40776 (PubMed:1989883).CuratedAdd BLAST24
Sequence conflicti1390 – 1486RRLRG…PSQAS → AACAVKISLLAACCSSMKQR DWMLVLSPRCLNCVSVCKCN SSSQRRKISARRKAPPINWC VKSSRIPNTFMSSACEDLRR NSLKRFQELTKRLLRRVKIK QQCRLFFFRKLRFCTKKVAH YGALFFKLLYIRLCKNVRRL YTEDKPDE in CAA40776 (PubMed:1989883).CuratedAdd BLAST97

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X57550 Genomic DNA Translation: CAA40776.1
D31701 Genomic DNA Translation: BAA06510.1
U00096 Genomic DNA Translation: AAC74010.1
AP009048 Genomic DNA Translation: BAA35670.1
D26440 Genomic DNA Translation: BAA05459.1

Protein sequence database of the Protein Information Resource

More...PIRi		C64832
JH0228

NCBI Reference Sequences

More...RefSeqi		NP_415444.1, NC_000913.3
WP_000572698.1, NZ_LN832404.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAC74010; AAC74010; b0924
BAA35670; BAA35670; BAA35670

Database of genes from NCBI RefSeq genomes

More...GeneIDi		945549

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		ecj:JW0907
eco:b0924

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|1411691.4.peg.1352

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X57550 Genomic DNA Translation: CAA40776.1
D31701 Genomic DNA Translation: BAA06510.1
U00096 Genomic DNA Translation: AAC74010.1
AP009048 Genomic DNA Translation: BAA35670.1
D26440 Genomic DNA Translation: BAA05459.1
PIRiC64832
JH0228
RefSeqiNP_415444.1, NC_000913.3
WP_000572698.1, NZ_LN832404.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1QHLX-ray2.20A1-227[»]
2WMMX-ray2.30A/B645-804[»]
3IBPX-ray3.10A566-863[»]
4MN4X-ray2.30C/D645-804[»]
6H2XX-ray2.60A333-526[»]
A893-1053[»]
SMRiP22523
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi4261687, 403 interactors
ComplexPortaliCPX-1090 MukBEF condensin complex
DIPiDIP-10273N
IntActiP22523, 58 interactors
MINTiP22523
STRINGi511145.b0924

Proteomic databases

EPDiP22523
jPOSTiP22523
PaxDbiP22523
PRIDEiP22523

Genome annotation databases

EnsemblBacteriaiAAC74010; AAC74010; b0924
BAA35670; BAA35670; BAA35670
GeneIDi945549
KEGGiecj:JW0907
eco:b0924
PATRICifig|1411691.4.peg.1352

Organism-specific databases

EchoBASE - an integrated post-genomic database for E. coli

More...EchoBASEi		EB0613

Phylogenomic databases

eggNOGiENOG4105DUC Bacteria
COG3096 LUCA
HOGENOMiHOG000278243
InParanoidiP22523
KOiK03632
PhylomeDBiP22523

Enzyme and pathway databases

BioCyciEcoCyc:EG10618-MONOMER
ECOL316407:JW0907-MONOMER

Miscellaneous databases

EvolutionaryTraceiP22523

Protein Ontology

More...PROi		PR:P22523

Family and domain databases

Gene3Di1.20.1060.30, 1 hit
HAMAPiMF_01800 MukB, 1 hit
InterProiView protein in InterPro
IPR012090 MukB
IPR032520 MukB_hinge
IPR042501 MukB_hinge_sf
IPR007406 MukB_N_dom
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF04310 MukB, 1 hit
PF16330 MukB_hinge, 1 hit
PIRSFiPIRSF005246 MukB, 1 hit
SUPFAMiSSF52540 SSF52540, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMUKB_ECOLI
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P22523
Secondary accession number(s): P71227, P77164, Q47398
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: July 15, 1998
Last modified: November 13, 2019
This is version 184 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  3. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again