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UniProtKB - P22452 (RL39_HALMA)

Entry version 141 (25 May 2022)
Sequence version 2 (23 Jan 2007)
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Protein

50S ribosomal protein L39e

Gene

rpl39e

Organism
Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binds to the 23S rRNA. Forms part of the polypeptide exit tunnel.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
50S ribosomal protein L39e
Alternative name(s):
Hl39e
Hl46e
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rpl39e
Ordered Locus Names:rrnAC3112
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHaloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri272569 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaea › Euryarchaeota › Stenosarchaea group › Halobacteria › Halobacteriales › Haloarculaceae › Haloarcula ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001169 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemoved1 Publication
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001270472 – 5050S ribosomal protein L39eAdd BLAST49

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of the 50S ribosomal subunit.

Interacts weakly with protein L23.

2 Publications

Protein-protein interaction databases

Protein interaction database and analysis system

More...IntActi		P22452, 2 interactors

STRING: functional protein association networks

More...STRINGi		272569.rrnAC3112

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

150
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

AlphaFold Protein Structure Database

More...AlphaFoldDBi		P22452

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		P22452

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		P22452

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eL39 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		arCOG04177, Archaea

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_181948_4_0_2

Identification of Orthologs from Complete Genome Data

More...OMAi		PAWVIMK

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1620.10, 1 hit

HAMAP database of protein families

More...HAMAPi		MF_00629, Ribosomal_L39e, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000077, Ribosomal_L39
IPR020083, Ribosomal_L39_CS
IPR023626, Ribosomal_L39e_dom_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00832, Ribosomal_L39, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48662, SSF48662, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00051, RIBOSOMAL_L39E, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

P22452-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGKKSKATKK RLAKLDNQNS RVPAWVMLKT DREVQRNHKR RHWRRNDTDE
Length:50
Mass (Da):6,115
Last modified:January 23, 2007 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4999D410AB7B331A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
X55007 Genomic DNA Translation: CAA38750.1
AY596297 Genomic DNA Translation: AAV47823.1

Protein sequence database of the Protein Information Resource

More...PIRi		S13066, R6HS39

NCBI Reference Sequences

More...RefSeqi		WP_004518346.1, NZ_CP039138.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...EnsemblBacteriai		AAV47823; AAV47823; rrnAC3112

Database of genes from NCBI RefSeq genomes

More...GeneIDi		40153923
64823662

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hma:rrnAC3112

Pathosystems Resource Integration Center (PATRIC)

More...PATRICi		fig|272569.17.peg.3654

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X55007 Genomic DNA Translation: CAA38750.1
AY596297 Genomic DNA Translation: AAV47823.1
PIRiS13066, R6HS39
RefSeqiWP_004518346.1, NZ_CP039138.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1FFKX-ray2.40Y2-50[»]
1JJ2X-ray2.4012-49[»]
1K73X-ray3.0132-49[»]
1K8AX-ray3.0032-49[»]
1K9MX-ray3.0032-49[»]
1KC8X-ray3.0132-49[»]
1KD1X-ray3.0032-49[»]
1KQSX-ray3.1012-49[»]
1M1KX-ray3.2032-49[»]
1M90X-ray2.8032-49[»]
1N8RX-ray3.0032-49[»]
1NJIX-ray3.0032-49[»]
1Q7YX-ray3.2032-49[»]
1Q81X-ray2.9532-49[»]
1Q82X-ray2.9832-49[»]
1Q86X-ray3.0032-49[»]
1QVFX-ray3.1012-49[»]
1QVGX-ray2.9012-49[»]
1S72X-ray2.4021-50[»]
1VQ4X-ray2.7021-50[»]
1VQ5X-ray2.6021-50[»]
1VQ6X-ray2.7021-50[»]
1VQ7X-ray2.5021-50[»]
1VQ8X-ray2.2021-50[»]
1VQ9X-ray2.4021-50[»]
1VQKX-ray2.3021-50[»]
1VQLX-ray2.3021-50[»]
1VQMX-ray2.3021-50[»]
1VQNX-ray2.4021-50[»]
1VQOX-ray2.2021-50[»]
1VQPX-ray2.2521-50[»]
1W2BX-ray3.5012-49[»]
1YHQX-ray2.4021-50[»]
1YI2X-ray2.6521-50[»]
1YIJX-ray2.6021-50[»]
1YITX-ray2.8021-50[»]
1YJ9X-ray2.9021-50[»]
1YJNX-ray3.0021-50[»]
1YJWX-ray2.9021-50[»]
2OTJX-ray2.9021-50[»]
2OTLX-ray2.7021-50[»]
2QA4X-ray3.0021-50[»]
2QEXX-ray2.9021-50[»]
3CC2X-ray2.4021-50[»]
3CC4X-ray2.7021-50[»]
3CC7X-ray2.7021-50[»]
3CCEX-ray2.7521-50[»]
3CCJX-ray2.7021-50[»]
3CCLX-ray2.9021-50[»]
3CCMX-ray2.5521-50[»]
3CCQX-ray2.9021-50[»]
3CCRX-ray3.0021-50[»]
3CCSX-ray2.9521-50[»]
3CCUX-ray2.8021-50[»]
3CCVX-ray2.9021-50[»]
3CD6X-ray2.7521-50[»]
3CMAX-ray2.8021-50[»]
3CMEX-ray2.9521-50[»]
3CPWX-ray2.7011-50[»]
3CXCX-ray3.0012-50[»]
3G4SX-ray3.2021-50[»]
3G6EX-ray2.7021-50[»]
3G71X-ray2.8521-50[»]
3I55X-ray3.1121-50[»]
3I56X-ray2.9021-50[»]
3OW2X-ray2.7012-50[»]
4ADXelectron microscopy6.6021-50[»]
4V9FX-ray2.4021-50[»]
AlphaFoldDBiP22452
SMRiP22452
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

IntActiP22452, 2 interactors
STRINGi272569.rrnAC3112

Genome annotation databases

EnsemblBacteriaiAAV47823; AAV47823; rrnAC3112
GeneIDi40153923
64823662
KEGGihma:rrnAC3112
PATRICifig|272569.17.peg.3654

Phylogenomic databases

eggNOGiarCOG04177, Archaea
HOGENOMiCLU_181948_4_0_2
OMAiPAWVIMK

Miscellaneous databases

EvolutionaryTraceiP22452

Family and domain databases

Gene3Di1.10.1620.10, 1 hit
HAMAPiMF_00629, Ribosomal_L39e, 1 hit
InterProiView protein in InterPro
IPR000077, Ribosomal_L39
IPR020083, Ribosomal_L39_CS
IPR023626, Ribosomal_L39e_dom_sf
PfamiView protein in Pfam
PF00832, Ribosomal_L39, 1 hit
SUPFAMiSSF48662, SSF48662, 1 hit
PROSITEiView protein in PROSITE
PS00051, RIBOSOMAL_L39E, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiRL39_HALMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: P22452
Secondary accession number(s): Q5UY30
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: January 23, 2007
Last modified: May 25, 2022
This is version 141 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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